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Author: Pak C Sham

Rankings

  • All-time downloads: 17,548 (rank: 18,172 )
  • Categories:
    • bioinformatics: 2,187 (rank: 9,566 (tie) )
    • genetics: 4,989 (rank: 4,815 (tie) )
    • genomics: 7,327 (rank: 3,913 )
    • neuroscience: 564 (rank: 61,650 (tie) )
    • psychiatry and clinical psychology: 1,052 (rank: 2,075 (tie) )
    • systems biology: 750 (rank: 8,562 (tie) )

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Preprints

INSIDER: Interpretable Sparse Matrix Decomposition for Bulk RNA Expression Data Analysis

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Polygenic scores via penalized regression on summary statistics

genomics more details view paper
  • Downloaded 3,723 times
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    • Site-wide: 5,192
    • In genomics: 495
  • Year to date:
    • Site-wide: 9,180
  • Since beginning of last month:
    • Site-wide: 10,840

Polygenic scores for UK Biobank scale data

genomics more details view paper
  • Downloaded 3,121 times
  • Download rankings, all-time:
    • Site-wide: 6,735
    • In genomics: 622
  • Year to date:
    • Site-wide: 50,372
  • Since beginning of last month:
    • Site-wide: 21,266

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

genetics more details view paper
  • Downloaded 2,855 times
  • Download rankings, all-time:
    • Site-wide: 7,615
    • In genetics: 281
  • Year to date:
    • Site-wide: 4,297
  • Since beginning of last month:
    • Site-wide: 22,543

LFMD: detecting low-frequency mutations in high-depth genome sequencing data without molecular tags

bioinformatics more details view paper
  • Downloaded 1,408 times
  • Download rankings, all-time:
    • Site-wide: 22,506
    • In bioinformatics: 2,436
  • Year to date:
    • Site-wide: 50,343
  • Since beginning of last month:
    • Site-wide: 68,389

WITER: A powerful method for the estimation of cancer-driver genes using a weighted iterative regression accurately modelling background mutation rate

bioinformatics more details view paper
  • Downloaded 851 times
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    • Site-wide: 49,139
    • In bioinformatics: 4,855
  • Year to date:
    • Site-wide: 110,536
  • Since beginning of last month:
    • Site-wide: 127,034

The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.

genetics more details view paper
  • Downloaded 823 times
  • Download rankings, all-time:
    • Site-wide: 51,683
    • In genetics: 2,184
  • Year to date:
    • Site-wide: 65,300
  • Since beginning of last month:
    • Site-wide: 43,765

Deviation from baseline mutation burden provides powerful and robust rare-variants association test for complex diseases

genetics more details view paper
  • Downloaded 782 times
  • Download rankings, all-time:
    • Site-wide: 55,790
    • In genetics: 2,144
  • Year to date:
    • Site-wide: 100,740
  • Since beginning of last month:
    • Site-wide: 109,147

DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics

systems biology more details view paper
  • Downloaded 779 times
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    • Site-wide: 56,082
    • In systems biology: 1,120
  • Year to date:
    • Site-wide: 90,073
  • Since beginning of last month:
    • Site-wide: 108,854

Whole genome base-wise aggregation and functional prediction for human non-coding regulatory variants

genomics more details view paper
  • Downloaded 738 times
  • Download rankings, all-time:
    • Site-wide: 60,669
    • In genomics: 4,162
  • Year to date:
    • Site-wide: 143,624
  • Since beginning of last month:
    • Site-wide: 122,381

Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls

psychiatry and clinical psychology more details view paper
  • Downloaded 613 times
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    • Site-wide: 78,188
    • In psychiatry and clinical psychology: 342
  • Year to date:
    • Site-wide: 142,380
  • Since beginning of last month:
    • Site-wide: 150,986

Cannabis-associated symptom profiles in patients with first episode psychosis and population controls

neuroscience more details view paper
  • Downloaded 584 times
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    • Site-wide: 83,188
    • In neuroscience: 11,580
  • Year to date:
    • Site-wide: 149,192
  • Since beginning of last month:
    • Site-wide: 144,169

Use of multiple Polygenic Risk Scores for distinguishing Schizophrenia-spectrum disorder and Affective psychosis categories; the EUGEI study

psychiatry and clinical psychology more details view paper
  • Downloaded 485 times
  • Download rankings, all-time:
    • Site-wide: 103,588
    • In psychiatry and clinical psychology: 513
  • Year to date:
    • Site-wide: 37,196
  • Since beginning of last month:
    • Site-wide: 135,941

Estimating driver-tissues by robust selective expression of genes associated with complex diseases or traits

genetics more details view paper
  • Downloaded 402 times
  • Download rankings, all-time:
    • Site-wide: 124,366
    • In genetics: 4,647
  • Year to date:
    • Site-wide: 135,369
  • Since beginning of last month:
    • Site-wide: 128,039

Trans-ethnic polygenic analysis supports genetic overlaps of lumbar disc degeneration with height, body mass index, and bone mineral density

genetics more details view paper
  • Downloaded 334 times
  • Download rankings, all-time:
    • Site-wide: 144,464
    • In genetics: 5,338
  • Year to date:
    • Site-wide: 188,630
  • Since beginning of last month:
    • Site-wide: 120,684

Cross-phenotype relationship between opioid use disorder and suicide attempts: new evidence from polygenic association and Mendelian randomization analyses

psychiatry and clinical psychology more details view paper
  • Downloaded 50 times
  • Download rankings, all-time:
    • Site-wide: 208,260
    • In psychiatry and clinical psychology: None
  • Year to date:
    • Site-wide: 166,139
  • Since beginning of last month:
    • Site-wide: 15,969

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