Author: Alexis Battle

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Preprints

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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The GTEx Consortium atlas of genetic regulatory effects across human tissues

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  • In genetics: 28
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Co-expression networks reveal the tissue-specific regulation of transcription and splicing

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In vivo CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer

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  • Site-wide: 4,461
  • In immunology: 165
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The impact of rare variation on gene expression across tissues

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  • Site-wide: 5,540
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Distant regulatory effects of genetic variation in multiple human tissues

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  • Site-wide: 6,011
  • In genomics: 586
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Addressing confounding artifacts in reconstruction of gene co-expression networks

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  • Site-wide: 7,595
  • In genomics: 764
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Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed

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  • Site-wide: 9,099
  • In genetics: 368
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Diverse transcriptomic signatures across human tissues identify functional rare genetic variation

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  • In genomics: 987
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ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study

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  • Site-wide: 12,663
  • In genetic and genomic medicine: 62
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Mechanisms of tissue-specific genetic regulation revealed by latent factors across eQTLs

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  • In genomics: 1,433
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  • Site-wide: 128,610
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  • Site-wide: 111,081

The architecture of brain co-expression reveals the brain-wide basis of disease susceptibility

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  • Site-wide: 95,917
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Genome-wide association and multi-omic analyses reveal new mechanisms for Heart Failure

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  • Site-wide: 22,691
  • In genetic and genomic medicine: 109
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GBAT: a gene-based association method for robust trans-gene regulation detection

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  • Site-wide: 24,327
  • In genetics: 1,037
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Single-Cell Sequencing Reveals Lineage-Specific Dynamic Genetic Regulation of Gene Expression During Human Cardiomyocyte Differentiation

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Network reconstruction for trans acting genetic loci using multi-omics data and prior information

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  • Site-wide: 38,187
  • In bioinformatics: 4,048
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Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits

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  • Site-wide: 42,469
  • In genetics: 1,800
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  • Site-wide: 140,033
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  • Site-wide: 97,608

Novel Aggregative trans-eQTL Association Analysis of Known Genetic Variants Detect Trait-specific Target Gene-sets

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  • Site-wide: 47,473
  • In genetic and genomic medicine: 235
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Redefining tissue specificity of genetic regulation of gene expression in the presence of allelic heterogeneity

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  • Site-wide: 51,144
  • In genetic and genomic medicine: 254
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Random Forest Factorization Reveals Latent Structure in Single Cell RNA Sequencing Data

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  • Site-wide: 66,266
  • In bioinformatics: 6,298
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Human embryoid bodies as a novel system for genomic studies of functionally diverse cell types

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  • Site-wide: 74,197
  • In genomics: 5,005
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