Author: Thomas Werge

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Preprints

Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample

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Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

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Common risk variants identified in autism spectrum disorder

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Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

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A Major Role for Common Genetic Variation in Anxiety Disorders

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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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Genome-wide association study identifies 48 common genetic variants associated with handedness

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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

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Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

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Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Genome-wide association study implicates CHRNA2 in cannabis use disorder

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Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

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Genome-wide association study of school grades identifies a genetic overlap between language ability, psychopathology and creativity

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Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

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Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

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The genetic structure of Norway

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The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

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Low frequency and rare coding variation contributes to multiple sclerosis risk

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Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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Impute.me: an open source, non-profit tool for using data from DTC genetic testing to calculate and interpret polygenic risk scores.

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Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD

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Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

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Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

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Gestational-age-dependent development of the neonatal metabolome

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Identification of shared and differentiating genetic risk for autism spectrum disorder, attention deficit hyperactivity disorder and case subgroups.

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Meta-analysis of Scandinavian Schizophrenia Exomes

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Polygenic prediction of school performance in children with and without psychiatric disorders

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Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

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The iPSYCH2015 Case-Cohort sample: updated directions for unravelling genetic and environmental architectures of severe mental disorders

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Accounting for age-of-onset and family history improves power in genome-wide association studies

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AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

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Genome-wide association study of febrile seizures identifies seven new loci implicating fever response and neuronal excitability genes

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A dominant-negative variant in the dopamine transporter PDZ-binding motif is linked to parkinsonism and neuropsychiatric disease

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Elevated DNA Methylation Gestational Age is associated with the Risk of Later Bipolar Disorder and Anorexia Nervosa in Twins

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Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

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Mendelian randomization study of spermine oxidase and cancer risk

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Polygenic heterogeneity across obsessive-compulsive disorder subgroups defined by a comorbid diagnosis

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Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention deficit hyperactivity disorder

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Interplay of ADHD polygenic liability with birth-related, somatic and psychosocial factors in ADHD - a nationwide study

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