Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 57,915 bioRxiv papers from 266,490 authors.

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Preprints

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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  • In genetics: 11 out of 3,319
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  • Site-wide: 506 out of 57,915
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  • Site-wide: 1,352 out of 57,915

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 133 out of 57,915
  • In genetics: 12 out of 3,319
• Year to date:
  • Site-wide: 1,963 out of 57,915
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  • Site-wide: 8,360 out of 57,915

Common risk variants identified in autism spectrum disorder

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  • In genetics: 34 out of 3,319
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  • Site-wide: 670 out of 57,915
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  • Site-wide: 2,636 out of 57,915

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

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  • Site-wide: 308 out of 57,915
  • In genetics: 40 out of 3,319
• Year to date:
  • Site-wide: 106 out of 57,915
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  • Site-wide: 233 out of 57,915

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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  • In genetics: 228 out of 3,319
• Year to date:
  • Site-wide: 26,692 out of 57,915
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  • Site-wide: 20,305 out of 57,915

A major role for common genetic variation in anxiety disorders

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  • In genetics: 251 out of 3,319
• Year to date:
  • Site-wide: 1,723 out of 57,915
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  • Site-wide: 2,928 out of 57,915

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 3,045 out of 57,915
  • In genetics: 277 out of 3,319
• Year to date:
  • Site-wide: 41,125 out of 57,915
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  • Site-wide: 32,809 out of 57,915

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • In genomics: 800 out of 4,060
• Year to date:
  • Site-wide: 16,669 out of 57,915
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  • Site-wide: 34,436 out of 57,915

ASD and ADHD have a similar burden of rare protein-truncating variants

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  • In genetics: 448 out of 3,319
• Year to date:
  • Site-wide: 6,976 out of 57,915
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A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

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  • In genetics: 505 out of 3,319
• Year to date:
  • Site-wide: 13,710 out of 57,915
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  • Site-wide: 10,410 out of 57,915

Minimal phenotyping yields GWAS hits of low specificity for major depression

• Downloaded 998 times
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  • Site-wide: 6,566 out of 57,915
  • In genetics: 533 out of 3,319
• Year to date:
  • Site-wide: 2,431 out of 57,915
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  • Site-wide: 670 out of 57,915

Genome-wide association study implicates CHRNA2 in cannabis use disorder

• Downloaded 993 times
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  • Site-wide: 6,621 out of 57,915
  • In genomics: 1,090 out of 4,060
• Year to date:
  • Site-wide: 6,834 out of 57,915
• Since beginning of last month:
  • Site-wide: 8,563 out of 57,915

A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

• Downloaded 989 times
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  • Site-wide: 6,651 out of 57,915
  • In genetics: 536 out of 3,319
• Year to date:
  • Site-wide: 12,413 out of 57,915
• Since beginning of last month:
  • Site-wide: 22,426 out of 57,915

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

• Downloaded 974 times
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  • In genetics: 546 out of 3,319
• Year to date:
  • Site-wide: 1,991 out of 57,915
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  • Site-wide: 2,230 out of 57,915

Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

• Downloaded 936 times
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  • In genetics: 577 out of 3,319
• Year to date:
  • Site-wide: 8,382 out of 57,915
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  • Site-wide: 9,618 out of 57,915

Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

• Downloaded 725 times
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  • Site-wide: 10,694 out of 57,915
  • In genomics: 1,541 out of 4,060
• Year to date:
  • Site-wide: 14,387 out of 57,915
• Since beginning of last month:
  • Site-wide: 14,490 out of 57,915

Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

• Downloaded 667 times
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  • Site-wide: 12,038 out of 57,915
  • In genomics: 1,677 out of 4,060
• Year to date:
  • Site-wide: 25,037 out of 57,915
• Since beginning of last month:
  • Site-wide: 22,336 out of 57,915

Pharmacogenetics of antidepressant response: a polygenic approach

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  • Site-wide: 13,237 out of 57,915
  • In genetics: 945 out of 3,319
• Year to date:
  • Site-wide: 29,313 out of 57,915
• Since beginning of last month:
  • Site-wide: 33,805 out of 57,915

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

• Downloaded 606 times
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  • Site-wide: 13,701 out of 57,915
  • In genetics: 973 out of 3,319
• Year to date:
  • Site-wide: 40,239 out of 57,915
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  • Site-wide: 35,337 out of 57,915

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 477 times
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  • Site-wide: 18,659 out of 57,915
  • In genomics: 2,214 out of 4,060
• Year to date:
  • Site-wide: 43,066 out of 57,915
• Since beginning of last month:
  • Site-wide: 46,741 out of 57,915

Elevated polygenic burden for autism is associated with differential DNA methylation at birth.

• Downloaded 475 times
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  • Site-wide: 18,790 out of 57,915
  • In genetics: 1,286 out of 3,319
• Year to date:
  • Site-wide: 36,609 out of 57,915
• Since beginning of last month:
  • Site-wide: 28,505 out of 57,915

The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

• Downloaded 432 times
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  • Site-wide: 20,968 out of 57,915
  • In neuroscience: 3,501 out of 10,207
• Year to date:
  • Site-wide: 30,960 out of 57,915
• Since beginning of last month:
  • Site-wide: 28,875 out of 57,915

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

• Downloaded 372 times
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  • Site-wide: 24,593 out of 57,915
  • In genetics: 1,623 out of 3,319
• Year to date:
  • Site-wide: 25,496 out of 57,915
• Since beginning of last month:
  • Site-wide: 42,235 out of 57,915

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

• Downloaded 354 times
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  • Site-wide: 25,800 out of 57,915
  • In neuroscience: 4,374 out of 10,207
• Year to date:
  • Site-wide: 20,156 out of 57,915
• Since beginning of last month:
  • Site-wide: 20,523 out of 57,915

Genetic variation in the Major Histocompatibility Complex and association with depression

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  • Site-wide: 32,941 out of 57,915
  • In genetics: 2,101 out of 3,319
• Year to date:
  • Site-wide: 24,345 out of 57,915
• Since beginning of last month:
  • Site-wide: 21,839 out of 57,915

Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

• Downloaded 265 times
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  • Site-wide: 33,368 out of 57,915
  • In genetics: 2,134 out of 3,319
• Year to date:
  • Site-wide: 18,276 out of 57,915
• Since beginning of last month:
  • Site-wide: 18,607 out of 57,915

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 243 times
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  • Site-wide: 35,627 out of 57,915
  • In genetics: 2,234 out of 3,319
• Year to date:
  • Site-wide: 42,257 out of 57,915
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  • Site-wide: 30,986 out of 57,915

Statin treatment and the risk of depression

• Downloaded 147 times
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  • Site-wide: 46,975 out of 57,915
  • In epidemiology: 982 out of 1,556
• Year to date:
  • Site-wide: 37,590 out of 57,915
• Since beginning of last month:
  • Site-wide: 29,929 out of 57,915

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

• Downloaded 95 times
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  • Site-wide: 53,090 out of 57,915
  • In bioinformatics: 5,633 out of 5,899
• Year to date:
  • Site-wide: 34,314 out of 57,915
• Since beginning of last month:
  • Site-wide: 4,703 out of 57,915