Author: Ole Mors

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Preprints

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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  • Site-wide: 669
  • In genetics: 18
• Year to date:
  • Site-wide: 5,861
• Since beginning of last month:
  • Site-wide: 4,938

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

• Downloaded 10,138 times
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  • Site-wide: 746
  • In genetics: 22
• Year to date:
  • Site-wide: 3,908
• Since beginning of last month:
  • Site-wide: 3,746

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,364 times
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  • Site-wide: 822
  • In genetics: 25
• Year to date:
  • Site-wide: 24,034
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  • Site-wide: 27,228

Common risk variants identified in autism spectrum disorder

• Downloaded 7,739 times
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  • Site-wide: 1,053
  • In genetics: 34
• Year to date:
  • Site-wide: 2,050
• Since beginning of last month:
  • Site-wide: 2,076

Genomewide association study identifies 30 loci associated with bipolar disorder

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  • Site-wide: 1,138
  • In genetics: 38
• Year to date:
  • Site-wide: 16,809
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  • Site-wide: 15,045

A Major Role for Common Genetic Variation in Anxiety Disorders

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  • Site-wide: 3,690
  • In genetics: 162
• Year to date:
  • Site-wide: 7,994
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  • Site-wide: 5,861

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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  • Site-wide: 5,249
  • In genetics: 247
• Year to date:
  • Site-wide: 12,572
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  • Site-wide: 16,146

Minimal phenotyping yields GWAS hits of reduced specificity for major depression

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  • Site-wide: 6,954
  • In genetics: 339
• Year to date:
  • Site-wide: 37,563
• Since beginning of last month:
  • Site-wide: 29,606

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 8,331
  • In genetics: 405
• Year to date:
  • Site-wide: 32,065
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  • Site-wide: 27,313

ASD and ADHD have a similar burden of rare protein-truncating variants

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  • Site-wide: 8,698
  • In genetics: 427
• Year to date:
  • Site-wide: 21,632
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  • Site-wide: 15,288

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

• Downloaded 1,664 times
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  • Site-wide: 9,252
  • In genetics: 457
• Year to date:
  • Site-wide: 16,828
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  • Site-wide: 15,110

Genome-wide association study implicates CHRNA2 in cannabis use disorder

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  • Site-wide: 9,401
  • In genomics: 1,054
• Year to date:
  • Site-wide: 20,545
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  • Site-wide: 17,176

Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

• Downloaded 1,557 times
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  • Site-wide: 10,180
  • In psychiatry and clinical psychology: 32
• Year to date:
  • Site-wide: 2,810
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  • Site-wide: 3,605

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 11,327
  • In genomics: 1,259
• Year to date:
  • Site-wide: 61,679
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  • Site-wide: 61,992

Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

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  • Site-wide: 11,877
  • In genetic and genomic medicine: 39
• Year to date:
  • Site-wide: 2,361
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  • Site-wide: 1,262

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

• Downloaded 1,396 times
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  • Site-wide: 11,972
  • In genetics: 605
• Year to date:
  • Site-wide: 42,429
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  • Site-wide: 61,547

Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

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  • Site-wide: 13,730
  • In genetics: 702
• Year to date:
  • Site-wide: 59,151
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  • Site-wide: 43,078

A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

• Downloaded 1,155 times
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  • Site-wide: 15,935
  • In genetics: 805
• Year to date:
  • Site-wide: 75,590
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  • Site-wide: 95,775

Genome-wide association study of school grades identifies a genetic overlap between language ability, psychopathology and creativity

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  • Site-wide: 17,704
  • In genomics: 1,842
• Year to date:
  • Site-wide: 17,605
• Since beginning of last month:
  • Site-wide: 28,646

Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

• Downloaded 1,062 times
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  • Site-wide: 18,036
  • In genomics: 1,870
• Year to date:
  • Site-wide: 46,222
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  • Site-wide: 33,641

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 893 times
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  • Site-wide: 23,246
  • In genetics: 1,151
• Year to date:
  • Site-wide: 3,619
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  • Site-wide: 2,847

Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

• Downloaded 889 times
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  • Site-wide: 23,388
  • In genomics: 2,289
• Year to date:
  • Site-wide: 51,831
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  • Site-wide: 44,405

Pharmacogenetics of antidepressant response: a polygenic approach

• Downloaded 886 times
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  • Site-wide: 23,507
  • In genetics: 1,165
• Year to date:
  • Site-wide: 64,431
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  • Site-wide: 67,421

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 835 times
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  • Site-wide: 25,537
  • In genetics: 1,263
• Year to date:
  • Site-wide: 59,000
• Since beginning of last month:
  • Site-wide: 43,816

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

• Downloaded 770 times
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  • Site-wide: 28,562
  • In genetics: 1,425
• Year to date:
  • Site-wide: 49,771
• Since beginning of last month:
  • Site-wide: 38,622

Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

• Downloaded 741 times
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  • Site-wide: 30,131
  • In genetics: 1,491
• Year to date:
  • Site-wide: 25,862
• Since beginning of last month:
  • Site-wide: None

The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

• Downloaded 660 times
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  • Site-wide: 35,373
  • In neuroscience: 4,983
• Year to date:
  • Site-wide: 40,761
• Since beginning of last month:
  • Site-wide: 24,479

Elevated polygenic burden for autism is associated with differential DNA methylation at birth.

• Downloaded 638 times
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  • Site-wide: 36,888
  • In genetics: 1,802
• Year to date:
  • Site-wide: 86,653
• Since beginning of last month:
  • Site-wide: 81,205

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

• Downloaded 598 times
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  • Site-wide: 40,070
  • In neuroscience: 5,750
• Year to date:
  • Site-wide: 71,433
• Since beginning of last month:
  • Site-wide: 82,306

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 585 times
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  • Site-wide: 41,203
  • In genomics: 3,423
• Year to date:
  • Site-wide: 111,661
• Since beginning of last month:
  • Site-wide: 96,130

Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD

• Downloaded 562 times
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  • Site-wide: 43,329
  • In genomics: 3,554
• Year to date:
  • Site-wide: 39,997
• Since beginning of last month:
  • Site-wide: 43,069

Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

• Downloaded 531 times
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  • Site-wide: 46,400
  • In genetics: 2,229
• Year to date:
  • Site-wide: 87,274
• Since beginning of last month:
  • Site-wide: None

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 519 times
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  • Site-wide: 47,647
  • In genetics: 2,275
• Year to date:
  • Site-wide: 92,385
• Since beginning of last month:
  • Site-wide: 73,522

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

• Downloaded 506 times
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  • Site-wide: 49,117
  • In genetics: 2,347
• Year to date:
  • Site-wide: 108,087
• Since beginning of last month:
  • Site-wide: 99,557

Meta-analysis of Scandinavian Schizophrenia Exomes

• Downloaded 438 times
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  • Site-wide: 57,680
  • In genetics: 2,731
• Year to date:
  • Site-wide: 41,984
• Since beginning of last month:
  • Site-wide: 45,088

Genetic variation in the Major Histocompatibility Complex and association with depression

• Downloaded 422 times
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  • Site-wide: 59,899
  • In genetics: 2,832
• Year to date:
  • Site-wide: 109,387
• Since beginning of last month:
  • Site-wide: 75,701

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

• Downloaded 414 times
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  • Site-wide: 60,959
  • In genetic and genomic medicine: 183
• Year to date:
  • Site-wide: 10,935
• Since beginning of last month:
  • Site-wide: 17,773

Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

• Downloaded 318 times
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  • Site-wide: 77,145
  • In psychiatry and clinical psychology: 239
• Year to date:
  • Site-wide: 5,491
• Since beginning of last month:
  • Site-wide: 6,683

Polygenic prediction of school performance in children with and without psychiatric disorders

• Downloaded 317 times
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  • Site-wide: 77,359
  • In genetics: 3,584
• Year to date:
  • Site-wide: 53,044
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  • Site-wide: 40,301

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

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  • Site-wide: 87,204
  • In bioinformatics: 7,790
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  • Site-wide: None
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Statin treatment and the risk of depression

• Downloaded 267 times
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  • Site-wide: 87,550
  • In epidemiology: 3,567
• Year to date:
  • Site-wide: 67,165
• Since beginning of last month:
  • Site-wide: 37,464

The iPSYCH2015 Case-Cohort sample: updated directions for unravelling genetic and environmental architectures of severe mental disorders

• Downloaded 121 times
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  • Site-wide: 117,650
  • In epidemiology: 4,761
• Year to date:
  • Site-wide: 22,917
• Since beginning of last month:
  • Site-wide: 19,097

Genome-wide association study of febrile seizures identifies seven new loci implicating fever response and neuronal excitability genes

• Downloaded 109 times
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  • Site-wide: 119,908
  • In genetic and genomic medicine: 545
• Year to date:
  • Site-wide: 59,645
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  • Site-wide: 84,917