Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 57,793 bioRxiv papers from 266,023 authors.

Downloads per author, site-wide

Preprints

Meta-analysis of problematic alcohol use in 435,563 individuals identifies 29 risk variants and yields insights into biology, pleiotropy and causality

No bioRxiv download data for this paper yet.

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 8,665 times
• Download rankings, all-time:
  • Site-wide: 133 out of 57,793
  • In genetics: 12 out of 3,318
• Year to date:
  • Site-wide: 1,979 out of 57,793
• Since beginning of last month:
  • Site-wide: 9,624 out of 57,793

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

• Downloaded 3,495 times
• Download rankings, all-time:
  • Site-wide: 756 out of 57,793
  • In genetics: 74 out of 3,318
• Year to date:
  • Site-wide: 377 out of 57,793
• Since beginning of last month:
  • Site-wide: 3,133 out of 57,793

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

• Downloaded 2,247 times
• Download rankings, all-time:
  • Site-wide: 1,687 out of 57,793
  • In genetics: 163 out of 3,318
• Year to date:
  • Site-wide: 20,927 out of 57,793
• Since beginning of last month:
  • Site-wide: 18,187 out of 57,793

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

• Downloaded 1,801 times
• Download rankings, all-time:
  • Site-wide: 2,451 out of 57,793
  • In genetics: 232 out of 3,318
• Year to date:
  • Site-wide: 16,534 out of 57,793
• Since beginning of last month:
  • Site-wide: 19,438 out of 57,793

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

• Downloaded 1,549 times
• Download rankings, all-time:
  • Site-wide: 3,162 out of 57,793
  • In genetics: 284 out of 3,318
• Year to date:
  • Site-wide: 3,318 out of 57,793
• Since beginning of last month:
  • Site-wide: 15,012 out of 57,793

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

• Downloaded 1,278 times
• Download rankings, all-time:
  • Site-wide: 4,360 out of 57,793
  • In genetics: 364 out of 3,318
• Year to date:
  • Site-wide: 6,187 out of 57,793
• Since beginning of last month:
  • Site-wide: 10,966 out of 57,793

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,260 times
• Download rankings, all-time:
  • Site-wide: 4,452 out of 57,793
  • In genomics: 798 out of 4,057
• Year to date:
  • Site-wide: 16,513 out of 57,793
• Since beginning of last month:
  • Site-wide: 33,956 out of 57,793

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

• Downloaded 1,095 times
• Download rankings, all-time:
  • Site-wide: 5,623 out of 57,793
  • In genetics: 463 out of 3,318
• Year to date:
  • Site-wide: 24,666 out of 57,793
• Since beginning of last month:
  • Site-wide: 28,964 out of 57,793

Minimal phenotyping yields GWAS hits of low specificity for major depression

• Downloaded 998 times
• Download rankings, all-time:
  • Site-wide: 6,532 out of 57,793
  • In genetics: 532 out of 3,318
• Year to date:
  • Site-wide: 2,412 out of 57,793
• Since beginning of last month:
  • Site-wide: 636 out of 57,793

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

• Downloaded 836 times
• Download rankings, all-time:
  • Site-wide: 8,654 out of 57,793
  • In genetics: 654 out of 3,318
• Year to date:
  • Site-wide: 3,249 out of 57,793
• Since beginning of last month:
  • Site-wide: 5,099 out of 57,793

The Stratification Of Major Depressive Disorder Into Genetic Subgroups

• Downloaded 798 times
• Download rankings, all-time:
  • Site-wide: 9,320 out of 57,793
  • In genetics: 698 out of 3,318
• Year to date:
  • Site-wide: 23,174 out of 57,793
• Since beginning of last month:
  • Site-wide: 20,750 out of 57,793

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

• Downloaded 690 times
• Download rankings, all-time:
  • Site-wide: 11,461 out of 57,793
  • In genetics: 821 out of 3,318
• Year to date:
  • Site-wide: 33,958 out of 57,793
• Since beginning of last month:
  • Site-wide: 38,792 out of 57,793

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

• Downloaded 606 times
• Download rankings, all-time:
  • Site-wide: 13,682 out of 57,793
  • In genetics: 968 out of 3,318
• Year to date:
  • Site-wide: 40,286 out of 57,793
• Since beginning of last month:
  • Site-wide: 52,901 out of 57,793

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

• Downloaded 603 times
• Download rankings, all-time:
  • Site-wide: 13,781 out of 57,793
  • In genetics: 977 out of 3,318
• Year to date:
  • Site-wide: 48,148 out of 57,793
• Since beginning of last month:
  • Site-wide: 51,920 out of 57,793

Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

• Downloaded 545 times
• Download rankings, all-time:
  • Site-wide: 15,815 out of 57,793
  • In genetics: 1,092 out of 3,318
• Year to date:
  • Site-wide: 15,687 out of 57,793
• Since beginning of last month:
  • Site-wide: 23,164 out of 57,793

Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

• Downloaded 542 times
• Download rankings, all-time:
  • Site-wide: 15,908 out of 57,793
  • In genomics: 2,018 out of 4,057
• Year to date:
  • Site-wide: 56,008 out of 57,793
• Since beginning of last month:
  • Site-wide: 51,389 out of 57,793

A validation of the diathesis-stress model for depression in Generation Scotland.

• Downloaded 406 times
• Download rankings, all-time:
  • Site-wide: 22,364 out of 57,793
  • In genomics: 2,467 out of 4,057
• Year to date:
  • Site-wide: 16,596 out of 57,793
• Since beginning of last month:
  • Site-wide: 24,863 out of 57,793

Accelerated Epigenetic Ageing in Major Depressive Disorder

• Downloaded 384 times
• Download rankings, all-time:
  • Site-wide: 23,765 out of 57,793
  • In genomics: 2,567 out of 4,057
• Year to date:
  • Site-wide: 35,704 out of 57,793
• Since beginning of last month:
  • Site-wide: 48,142 out of 57,793

Dissection of Major Depressive Disorder using polygenic risk scores for Schizophrenia in two independent cohort.

• Downloaded 301 times
• Download rankings, all-time:
  • Site-wide: 29,932 out of 57,793
  • In neuroscience: 5,087 out of 10,199
• Year to date:
  • Site-wide: 55,976 out of 57,793
• Since beginning of last month:
  • Site-wide: 55,365 out of 57,793

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

• Downloaded 301 times
• Download rankings, all-time:
  • Site-wide: 29,957 out of 57,793
  • In genetics: 1,926 out of 3,318
• Year to date:
  • Site-wide: 53,718 out of 57,793
• Since beginning of last month:
  • Site-wide: 55,165 out of 57,793

Response to 'Problems in interpreting and using GWAS of conditional phenotypes illustrated by alcohol GWAS'

• Downloaded 296 times
• Download rankings, all-time:
  • Site-wide: 30,426 out of 57,793
  • In genetics: 1,954 out of 3,318
• Year to date:
  • Site-wide: 42,054 out of 57,793
• Since beginning of last month:
  • Site-wide: 50,361 out of 57,793

A meta-analysis of genome-wide association studies of epigenetic age acceleration

• Downloaded 294 times
• Download rankings, all-time:
  • Site-wide: 30,600 out of 57,793
  • In genetics: 1,967 out of 3,318
• Year to date:
  • Site-wide: 8,725 out of 57,793
• Since beginning of last month:
  • Site-wide: 14,342 out of 57,793

Genome-wide by environment interaction studies (GWEIS) of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

• Downloaded 243 times
• Download rankings, all-time:
  • Site-wide: 35,544 out of 57,793
  • In genetics: 2,224 out of 3,318
• Year to date:
  • Site-wide: 24,031 out of 57,793
• Since beginning of last month:
  • Site-wide: 33,459 out of 57,793

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests its role in anxiety and male alcohol intake.

• Downloaded 230 times
• Download rankings, all-time:
  • Site-wide: 36,946 out of 57,793
  • In genetics: 2,312 out of 3,318
• Year to date:
  • Site-wide: 12,699 out of 57,793
• Since beginning of last month:
  • Site-wide: 41,445 out of 57,793

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

• Downloaded 224 times
• Download rankings, all-time:
  • Site-wide: 37,580 out of 57,793
  • In genetics: 2,333 out of 3,318
• Year to date:
  • Site-wide: 13,191 out of 57,793
• Since beginning of last month:
  • Site-wide: 44,365 out of 57,793

Epigenetic signatures of starting and stopping smoking

• Downloaded 198 times
• Download rankings, all-time:
  • Site-wide: 40,613 out of 57,793
  • In genomics: 3,441 out of 4,057
• Year to date:
  • Site-wide: 55,825 out of 57,793
• Since beginning of last month:
  • Site-wide: 54,979 out of 57,793

Trajectory of brain maturation in young individuals at familial risk of mood disorder

• Downloaded 196 times
• Download rankings, all-time:
  • Site-wide: 40,845 out of 57,793
  • In neuroscience: 7,073 out of 10,199
• Year to date:
  • Site-wide: 15,701 out of 57,793
• Since beginning of last month:
  • Site-wide: 17,987 out of 57,793

Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

• Downloaded 178 times
• Download rankings, all-time:
  • Site-wide: 42,972 out of 57,793
  • In genetics: 2,637 out of 3,318
• Year to date:
  • Site-wide: 52,660 out of 57,793
• Since beginning of last month:
  • Site-wide: 51,818 out of 57,793

Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

• Downloaded 99 times
• Download rankings, all-time:
  • Site-wide: 52,600 out of 57,793
  • In neuroscience: 9,235 out of 10,199
• Year to date:
  • Site-wide: 32,830 out of 57,793
• Since beginning of last month:
  • Site-wide: 38,680 out of 57,793

Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

• Downloaded 97 times
• Download rankings, all-time:
  • Site-wide: 52,784 out of 57,793
  • In bioinformatics: 5,610 out of 5,897
• Year to date:
  • Site-wide: 33,387 out of 57,793
• Since beginning of last month:
  • Site-wide: 32,067 out of 57,793

Educational attainment causally impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study in ~ 780,000 study participants

• Downloaded 42 times
• Download rankings, all-time:
  • Site-wide: 56,368 out of 57,793
  • In epidemiology: 1,554 out of 1,556
• Year to date:
  • Site-wide: 53,465 out of 57,793
• Since beginning of last month:
  • Site-wide: None out of 57,793