Author: David M Howard

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Preprints

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

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Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

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Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

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Factors associated with sharing email information and mental health survey participation in large population cohorts

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Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

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Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

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A meta-analysis of genome-wide association studies of epigenetic age acceleration

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Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

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Accelerated Epigenetic Ageing in Major Depressive Disorder

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Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

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Using Major Depression Polygenic Risk Scores to Explore the Depressive Symptom Continuum

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Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

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Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

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Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

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