Author: Hongyu Zhao
- ORCiD: http://orcid.org/0000-0003-1195-9607
- Most recently observed institution: Department of Genetics, Yale School of Medicine, New Haven, CT, USA; Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA
Rankings
- All-time downloads: 73,046 (rank: 3,327 )
- Categories:
- bioinformatics: 11,492 (rank: 1,099 )
- cancer biology: 475 (rank: 34,237 (tie) )
- cardiovascular medicine: 458 (rank: 3,086 (tie) )
- cell biology: 5,653 (rank: 1,248 (tie) )
- epidemiology: 737 (rank: 20,855 (tie) )
- genetic and genomic medicine: 7,250 (rank: 438 )
- genetics: 24,072 (rank: 512 )
- genomics: 7,330 (rank: 4,173 (tie) )
- immunology: 5,358 (rank: 3,310 (tie) )
- infectious diseases: 5,394 (rank: 12,777 (tie) )
- neuroscience: 3,529 (rank: 10,274 (tie) )
- plant biology: 152 (rank: 27,780 (tie) )
Downloads per author, site-wide
Preprints
Androgen regulates SARS-CoV-2 receptor levels and is associated with severe COVID-19 symptoms in men
cell biology more details view paper- Downloaded 5,659 times
- Download rankings, all-time:
- Site-wide: 2,959
- In cell biology: 45
- Year to date:
- Site-wide: 82,534
- Since beginning of last month:
- Site-wide: 45,440
Single-Cell Omics Reveals Dyssynchrony of the Innate and Adaptive Immune System in Progressive COVID-19
infectious diseases more details view paper- Downloaded 5,420 times
- Download rankings, all-time:
- Site-wide: 3,140
- In infectious diseases: 782
- Year to date:
- Site-wide: 37,048
- Since beginning of last month:
- Site-wide: 22,097
Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes
genomics more details view paper- Downloaded 3,520 times
- Download rankings, all-time:
- Site-wide: 5,781
- In genomics: 538
- Year to date:
- Site-wide: 140,500
- Since beginning of last month:
- Site-wide: 30,209
A statistical framework for cross-tissue transcriptome-wide association analysis
genetics more details view paper- Downloaded 3,087 times
- Download rankings, all-time:
- Site-wide: 7,005
- In genetics: 255
- Year to date:
- Site-wide: 35,419
- Since beginning of last month:
- Site-wide: 90,481
AC-PCA: simultaneous dimension reduction and adjustment for confounding variation
bioinformatics more details view paper- Downloaded 2,793 times
- Download rankings, all-time:
- Site-wide: 8,104
- In bioinformatics: 808
- Year to date:
- Site-wide: 30,003
- Since beginning of last month:
- Site-wide: 90,084
A reservoir of stem-like CD8 T cells in the tumor-draining lymph node maintains the ongoing anti-tumor immune response
immunology more details view paper- Downloaded 2,594 times
- Download rankings, all-time:
- Site-wide: 9,047
- In immunology: 351
- Year to date:
- Site-wide: 14,611
- Since beginning of last month:
- Site-wide: 24,966
Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways
genetics more details view paper- Downloaded 2,273 times
- Download rankings, all-time:
- Site-wide: 11,064
- In genetics: 420
- Year to date:
- Site-wide: 5,652
- Since beginning of last month:
- Site-wide: 13,039
Neoantigen-driven B cell and CD4+ T follicular helper cell collaboration promotes robust anti-tumor CD8+ T cell responses
immunology more details view paper- Downloaded 2,133 times
- Download rankings, all-time:
- Site-wide: 12,196
- In immunology: 467
- Year to date:
- Site-wide: 47,392
- Since beginning of last month:
- Site-wide: 95,326
Single-cell transcriptomic and proteomic analysis of Parkinson's disease Brains
neuroscience more details view paper- Downloaded 2,100 times
- Download rankings, all-time:
- Site-wide: 12,450
- In neuroscience: 1,323
- Year to date:
- Site-wide: 12,388
- Since beginning of last month:
- Site-wide: 4,259
Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
genetics more details view paper- Downloaded 2,085 times
- Download rankings, all-time:
- Site-wide: 12,615
- In genetics: 466
- Year to date:
- Site-wide: 132,539
- Since beginning of last month:
- Site-wide: 141,476
Local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
genetics more details view paper- Downloaded 2,054 times
- Download rankings, all-time:
- Site-wide: 12,884
- In genetics: 490
- Year to date:
- Site-wide: 14,469
- Since beginning of last month:
- Site-wide: 54,742
Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer
genetic and genomic medicine more details view paper- Downloaded 1,913 times
- Download rankings, all-time:
- Site-wide: 14,369
- In genetic and genomic medicine: 89
- Year to date:
- Site-wide: 28,320
- Since beginning of last month:
- Site-wide: 23,634
A powerful approach to estimating annotation-stratified genetic covariance using GWAS summary statistics
genetics more details view paper- Downloaded 1,840 times
- Download rankings, all-time:
- Site-wide: 15,273
- In genetics: 603
- Year to date:
- Site-wide: 118,743
- Since beginning of last month:
- Site-wide: 51,439
A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program
genetic and genomic medicine more details view paper- Downloaded 1,674 times
- Download rankings, all-time:
- Site-wide: 17,699
- In genetic and genomic medicine: 111
- Year to date:
- Site-wide: 27,288
- Since beginning of last month:
- Site-wide: 21,749
Genomic Characterization of Posttraumatic Stress Disorder in a Large US Military Veteran Sample
genetics more details view paper- Downloaded 1,537 times
- Download rankings, all-time:
- Site-wide: 20,229
- In genetics: 837
- Year to date:
- Site-wide: 23,520
- Since beginning of last month:
- Site-wide: 52,743
Mendelian Randomization for causal inference accounting for pleiotropy and sample structure using genome-wide summary statistics
genetics more details view paper- Downloaded 1,424 times
- Download rankings, all-time:
- Site-wide: 22,897
- In genetics: 925
- Year to date:
- Site-wide: 26,518
- Since beginning of last month:
- Site-wide: 36,895
Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer's disease
genetics more details view paper- Downloaded 1,409 times
- Download rankings, all-time:
- Site-wide: 23,303
- In genetics: 923
- Year to date:
- Site-wide: 132,635
- Since beginning of last month:
- Site-wide: 175,222
SCRIBE: a new approach to dropout imputation and batch effects correction for single-cell RNA-seq data
bioinformatics more details view paper- Downloaded 1,386 times
- Download rankings, all-time:
- Site-wide: 23,920
- In bioinformatics: 2,606
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 126,985
Measuring genetic variation in the multi-ethnic Million Veteran Program (MVP)
genetics more details view paper- Downloaded 1,300 times
- Download rankings, all-time:
- Site-wide: 26,524
- In genetics: 1,061
- Year to date:
- Site-wide: 82,622
- Since beginning of last month:
- Site-wide: 131,955
Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies
genetics more details view paper- Downloaded 1,166 times
- Download rankings, all-time:
- Site-wide: 31,482
- In genetics: 1,278
- Year to date:
- Site-wide: 23,248
- Since beginning of last month:
- Site-wide: 42,659
Mediated pleiotropy between psychiatric disorders and autoimmune disorders revealed by integrative analysis of multiple GWAS
genomics more details view paper- Downloaded 1,101 times
- Download rankings, all-time:
- Site-wide: 34,374
- In genomics: 2,791
- Year to date:
- Site-wide: 94,102
- Since beginning of last month:
- Site-wide: 117,063
Leveraging functional annotation to identify genes associated with complex diseases
genetics more details view paper- Downloaded 1,086 times
- Download rankings, all-time:
- Site-wide: 35,077
- In genetics: 1,377
- Year to date:
- Site-wide: 188,861
- Since beginning of last month:
- Site-wide: 154,106
Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424)
genetics more details view paper- Downloaded 1,034 times
- Download rankings, all-time:
- Site-wide: 37,877
- In genetics: 1,508
- Year to date:
- Site-wide: 167,663
- Since beginning of last month:
- Site-wide: 59,370
Comparison of methods for estimating genetic correlation between complex traits using GWAS summary statistics
genetics more details view paper- Downloaded 1,019 times
- Download rankings, all-time:
- Site-wide: 38,746
- In genetics: 1,534
- Year to date:
- Site-wide: 66,235
- Since beginning of last month:
- Site-wide: 162,205
Transcriptomic Organization of Human Posttraumatic Stress Disorder
genomics more details view paper- Downloaded 921 times
- Download rankings, all-time:
- Site-wide: 45,226
- In genomics: 3,427
- Year to date:
- Site-wide: 119,952
- Since beginning of last month:
- Site-wide: 188,185
Influence of blood pressure on pneumonia risk: Epidemiological association and Mendelian randomisation in the UK Biobank
genetic and genomic medicine more details view paper- Downloaded 874 times
- Download rankings, all-time:
- Site-wide: 49,126
- In genetic and genomic medicine: 312
- Year to date:
- Site-wide: 46,914
- Since beginning of last month:
- Site-wide: 66,121
TP53-mediated clonal hematopoiesis confers increased risk for incident peripheral artery disease
genetic and genomic medicine more details view paper- Downloaded 867 times
- Download rankings, all-time:
- Site-wide: 49,702
- In genetic and genomic medicine: 366
- Year to date:
- Site-wide: 1,203
- Since beginning of last month:
- Site-wide: 20,025
Leveraging Functional Annotations in Genetic Risk Prediction for Human Complex Diseases
bioinformatics more details view paper- Downloaded 829 times
- Download rankings, all-time:
- Site-wide: 53,190
- In bioinformatics: 5,242
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 201,506
A fast and robust Bayesian nonparametric method for prediction of complex traits using summary statistics
bioinformatics more details view paper- Downloaded 824 times
- Download rankings, all-time:
- Site-wide: 53,725
- In bioinformatics: 5,310
- Year to date:
- Site-wide: 126,177
- Since beginning of last month:
- Site-wide: 156,892
OTTERS: A powerful TWAS framework leveraging summary-level reference data
genetics more details view paper- Downloaded 821 times
- Download rankings, all-time:
- Site-wide: 53,997
- In genetics: 2,360
- Year to date:
- Site-wide: 2,059
- Since beginning of last month:
- Site-wide: 2,035
ResPAN: a powerful batch correction model forscRNA-seq data through residual adversarialnetworks
bioinformatics more details view paper- Downloaded 763 times
- Download rankings, all-time:
- Site-wide: 60,137
- In bioinformatics: 5,904
- Year to date:
- Site-wide: 109,696
- Since beginning of last month:
- Site-wide: 21,704
Three distinct velocities of elongating RNA polymerase define exons and introns
genomics more details view paper- Downloaded 748 times
- Download rankings, all-time:
- Site-wide: 61,966
- In genomics: 4,288
- Year to date:
- Site-wide: 168,910
- Since beginning of last month:
- Site-wide: 210,412
Application of a Novel Machine Learning Method to Big Data Infers a Relationship Between Asthma and the Development of Neoplasia
epidemiology more details view paper- Downloaded 747 times
- Download rankings, all-time:
- Site-wide: 62,122
- In epidemiology: 2,980
- Year to date:
- Site-wide: 92,297
- Since beginning of last month:
- Site-wide: 90,030
A Markov Random Field Model for Network-based Differential Expression Analysis of Single-cell RNA-seq Data
bioinformatics more details view paper- Downloaded 746 times
- Download rankings, all-time:
- Site-wide: 62,197
- In bioinformatics: 6,062
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 34,237
Benchmarking Automated Cell Type Annotation Tools for Single-cell ATAC-seq Data
bioinformatics more details view paper- Downloaded 731 times
- Download rankings, all-time:
- Site-wide: 64,154
- In bioinformatics: 6,424
- Year to date:
- Site-wide: 98,233
- Since beginning of last month:
- Site-wide: 7,616
Circadian Rhythm Analysis Using Wearable Device Data: A Novel Penalized Machine Learning Approach
neuroscience more details view paper- Downloaded 724 times
- Download rankings, all-time:
- Site-wide: 64,994
- In neuroscience: 9,203
- Year to date:
- Site-wide: 37,070
- Since beginning of last month:
- Site-wide: 65,111
Identifying Combinations of Cancer Drivers in Individual Patients
bioinformatics more details view paper- Downloaded 715 times
- Download rankings, all-time:
- Site-wide: 66,199
- In bioinformatics: 6,280
- Year to date:
- Site-wide: 171,574
- Since beginning of last month:
- Site-wide: 117,660
A Statistical Framework to Identify Cell Types Whose Genetically Regulated Proportions are Associated with Complex Diseases
genetic and genomic medicine more details view paper- Downloaded 686 times
- Download rankings, all-time:
- Site-wide: 70,188
- In genetic and genomic medicine: 451
- Year to date:
- Site-wide: 109,224
- Since beginning of last month:
- Site-wide: 51,063
Simultaneous and sequential multi-species coronavirus vaccination
immunology more details view paper- Downloaded 663 times
- Download rankings, all-time:
- Site-wide: 73,419
- In immunology: 2,411
- Year to date:
- Site-wide: 147,321
- Since beginning of last month:
- Site-wide: 41,825
Genetic Association of Arterial Stiffness Index with Blood Pressure and Coronary Artery Disease
bioinformatics more details view paper- Downloaded 660 times
- Download rankings, all-time:
- Site-wide: 74,010
- In bioinformatics: 6,969
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 210,225
Estimating cell-type-specific gene co-expression networks from bulk gene expression data with an application to Alzheimer's disease
bioinformatics more details view paper- Downloaded 656 times
- Download rankings, all-time:
- Site-wide: 74,589
- In bioinformatics: 7,073
- Year to date:
- Site-wide: 35,237
- Since beginning of last month:
- Site-wide: 28,688
Non-linear Archetypal Analysis of Single-cell RNA-seq Data by Deep Autoencoders
bioinformatics more details view paper- Downloaded 626 times
- Download rankings, all-time:
- Site-wide: 79,247
- In bioinformatics: 7,419
- Year to date:
- Site-wide: 32,888
- Since beginning of last month:
- Site-wide: 37,121
Comprehensive Analysis of Ubiquitously Expressed Genes in Human, From a Data-Driven Perspective
genomics more details view paper- Downloaded 622 times
- Download rankings, all-time:
- Site-wide: 79,819
- In genomics: 5,229
- Year to date:
- Site-wide: 48,302
- Since beginning of last month:
- Site-wide: 26,728
Correcting statistical bias in correlation-based kinship estimators
genetics more details view paper- Downloaded 525 times
- Download rankings, all-time:
- Site-wide: 98,541
- In genetics: 3,770
- Year to date:
- Site-wide: 64,387
- Since beginning of last month:
- Site-wide: 86,374
microRNA seedless sites attenuate strong-seed-site-mediated target repression
bioinformatics more details view paper- Downloaded 515 times
- Download rankings, all-time:
- Site-wide: 100,797
- In bioinformatics: 8,952
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 211,157
Identifying Modules of Cooperating Cancer Drivers
cancer biology more details view paper- Downloaded 479 times
- Download rankings, all-time:
- Site-wide: 109,231
- In cancer biology: 3,303
- Year to date:
- Site-wide: 85,919
- Since beginning of last month:
- Site-wide: 122,795
Hemodynamic Differences Between Women and Men with Elevated Blood Pressure in China: A Non-Invasive Assessment of 45,082 Adults Using Impedance Cardiography
cardiovascular medicine more details view paper- Downloaded 464 times
- Download rankings, all-time:
- Site-wide: 112,906
- In cardiovascular medicine: 292
- Year to date:
- Site-wide: 100,016
- Since beginning of last month:
- Site-wide: 96,687
Integrative Analyses Reveal Novel Disease-associated Loci and Genes for Idiopathic Pulmonary Fibrosis
genetic and genomic medicine more details view paper- Downloaded 452 times
- Download rankings, all-time:
- Site-wide: 115,910
- In genetic and genomic medicine: 770
- Year to date:
- Site-wide: 56,814
- Since beginning of last month:
- Site-wide: 45,133
Genomic Influences on Self-Reported Childhood Maltreatment
genomics more details view paper- Downloaded 450 times
- Download rankings, all-time:
- Site-wide: 116,509
- In genomics: 6,665
- Year to date:
- Site-wide: 193,691
- Since beginning of last month:
- Site-wide: 199,622
Retrospective Association Analysis of Longitudinal Binary Traits Identifies Important Loci and Pathways in Cocaine Use
genetics more details view paper- Downloaded 441 times
- Download rankings, all-time:
- Site-wide: 118,831
- In genetics: 4,469
- Year to date:
- Site-wide: 93,208
- Since beginning of last month:
- Site-wide: 195,741
Motor nuclei innervating eye muscles spared in mouse model of SOD1-linked ALS
neuroscience more details view paper- Downloaded 432 times
- Download rankings, all-time:
- Site-wide: 121,132
- In neuroscience: 17,622
- Year to date:
- Site-wide: 92,173
- Since beginning of last month:
- Site-wide: 149,801
Quantifying concordant genetic effects of de novo mutations on multiple disorders
genetics more details view paper- Downloaded 426 times
- Download rankings, all-time:
- Site-wide: 122,741
- In genetics: 4,606
- Year to date:
- Site-wide: 107,694
- Since beginning of last month:
- Site-wide: 84,720
Estimating genetic correlation jointly using individual-level and summary-level GWAS data
genetics more details view paper- Downloaded 387 times
- Download rankings, all-time:
- Site-wide: 133,900
- In genetics: 5,018
- Year to date:
- Site-wide: 109,735
- Since beginning of last month:
- Site-wide: 49,564
Inferring time-lagged causality using the derivative of single-cell expression
bioinformatics more details view paper- Downloaded 375 times
- Download rankings, all-time:
- Site-wide: 137,379
- In bioinformatics: 10,983
- Year to date:
- Site-wide: 149,711
- Since beginning of last month:
- Site-wide: 135,606
TRPV5, TRPV6, TRPM6, and TRPM7 do not contribute to hair-cell mechanotransduction
neuroscience more details view paper- Downloaded 359 times
- Download rankings, all-time:
- Site-wide: 141,928
- In neuroscience: 20,731
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 196,987
M-DATA: A Statistical Approach to Jointly Analyzing De Novo Mutations for Multiple Traits
genetic and genomic medicine more details view paper- Downloaded 336 times
- Download rankings, all-time:
- Site-wide: 149,148
- In genetic and genomic medicine: 1,052
- Year to date:
- Site-wide: 180,621
- Since beginning of last month:
- Site-wide: 158,627
Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression in the VA Health Care System
genetic and genomic medicine more details view paper- Downloaded 314 times
- Download rankings, all-time:
- Site-wide: 155,704
- In genetic and genomic medicine: 1,120
- Year to date:
- Site-wide: 42,843
- Since beginning of last month:
- Site-wide: 104,786
Automated Feature Extraction from Population Wearable Device Data Identified Novel Loci Associated with Sleep and Circadian Rhythms
genetics more details view paper- Downloaded 312 times
- Download rankings, all-time:
- Site-wide: 156,269
- In genetics: 5,781
- Year to date:
- Site-wide: 89,026
- Since beginning of last month:
- Site-wide: 186,072
Cell-type-specific co-expression inference from single cell RNA-sequencing data
bioinformatics more details view paper- Downloaded 193 times
- Download rankings, all-time:
- Site-wide: 189,064
- In bioinformatics: 15,309
- Year to date:
- Site-wide: 3,547
- Since beginning of last month:
- Site-wide: 1,218
Network Assisted Analysis of De Novo Variants Using Protein-Protein Interaction Information Identified 46 Candidate Genes for Congenital Heart Disease
genetic and genomic medicine more details view paper- Downloaded 163 times
- Download rankings, all-time:
- Site-wide: 195,509
- In genetic and genomic medicine: 1,510
- Year to date:
- Site-wide: 103,120
- Since beginning of last month:
- Site-wide: 137,401
AIM1-dependent high basal SA accumulation modulates stomatal aperture in rice
plant biology more details view paper- Downloaded 162 times
- Download rankings, all-time:
- Site-wide: 195,781
- In plant biology: 5,524
- Year to date:
- Site-wide: 31,227
- Since beginning of last month:
- Site-wide: 28,106
Quantifying constraint in human mitochondrial DNA
genetics more details view paper- Downloaded 147 times
- Download rankings, all-time:
- Site-wide: 198,808
- In genetics: None
- Year to date:
- Site-wide: 2,002
- Since beginning of last month:
- Site-wide: 2,963
Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program
genetics more details view paper- Downloaded 114 times
- Download rankings, all-time:
- Site-wide: 204,915
- In genetics: 7,143
- Year to date:
- Site-wide: 68,007
- Since beginning of last month:
- Site-wide: 41,649
Whole Exome Sequencing Analyses Support a Role of Vitamin D Metabolism in Ischemic Stroke
genetic and genomic medicine more details view paper- Downloaded 103 times
- Download rankings, all-time:
- Site-wide: 206,954
- In genetic and genomic medicine: 1,655
- Year to date:
- Site-wide: 98,981
- Since beginning of last month:
- Site-wide: 69,628
Statistical Assessment of Biomarker Replicability using MAJAR Method
genetic and genomic medicine more details view paper- Downloaded 67 times
- Download rankings, all-time:
- Site-wide: 213,453
- In genetic and genomic medicine: 1,740
- Year to date:
- Site-wide: 31,260
- Since beginning of last month:
- Site-wide: 5,721
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News
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