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Author: Hongyu Zhao

Rankings

  • All-time downloads: 54,693 (rank: 3,621 )
  • Categories:
    • bioinformatics: 8,192 (rank: 1,441 )
    • cancer biology: 390 (rank: 28,443 (tie) )
    • cardiovascular medicine: 199 (rank: 3,730 (tie) )
    • cell biology: 5,246 (rank: 969 (tie) )
    • epidemiology: 641 (rank: 17,221 (tie) )
    • genetic and genomic medicine: 4,311 (rank: 925 )
    • genetics: 19,636 (rank: 772 )
    • genomics: 6,500 (rank: 3,804 )
    • immunology: 3,710 (rank: 3,336 (tie) )
    • infectious diseases: 4,661 (rank: 11,039 (tie) )
    • neuroscience: 1,207 (rank: 25,189 (tie) )

Downloads per author, site-wide

Preprints

Network Assisted Analysis of De Novo Variants Using Protein-Protein Interaction Information Identified 46 Candidate Genes for Congenital Heart Disease

genetic and genomic medicine more details view paper

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Androgen regulates SARS-CoV-2 receptor levels and is associated with severe COVID-19 symptoms in men

cell biology more details view paper
  • Downloaded 5,246 times
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    • Site-wide: 2,486
    • In cell biology: 37
  • Year to date:
    • Site-wide: 5,401
  • Since beginning of last month:
    • Site-wide: 8,531

Single-Cell Omics Reveals Dyssynchrony of the Innate and Adaptive Immune System in Progressive COVID-19

infectious diseases more details view paper
  • Downloaded 4,661 times
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    • Site-wide: 2,940
    • In infectious diseases: 688
  • Year to date:
    • Site-wide: 3,662
  • Since beginning of last month:
    • Site-wide: 6,688

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

genomics more details view paper
  • Downloaded 3,235 times
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    • Site-wide: 4,927
    • In genomics: 486
  • Year to date:
    • Site-wide: 11,786
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    • Site-wide: 35,110

A statistical framework for cross-tissue transcriptome-wide association analysis

genetics more details view paper
  • Downloaded 2,922 times
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    • Site-wide: 5,722
    • In genetics: 229
  • Year to date:
    • Site-wide: 57,349
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    • Site-wide: 52,723

AC-PCA: simultaneous dimension reduction and adjustment for confounding variation

bioinformatics more details view paper
  • Downloaded 2,647 times
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    • Site-wide: 6,578
    • In bioinformatics: 672
  • Year to date:
    • Site-wide: 81,052
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    • Site-wide: 82,432

A reservoir of stem-like CD8 T cells in the tumor-draining lymph node maintains the ongoing anti-tumor immune response

immunology more details view paper
  • Downloaded 2,171 times
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    • Site-wide: 8,840
    • In immunology: 317
  • Year to date:
    • Site-wide: 1,767
  • Since beginning of last month:
    • Site-wide: 2,673

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

genetics more details view paper
  • Downloaded 1,971 times
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    • Site-wide: 10,207
    • In genetics: 418
  • Year to date:
    • Site-wide: 96,006
  • Since beginning of last month:
    • Site-wide: 96,901

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

genetics more details view paper
  • Downloaded 1,960 times
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    • Site-wide: 10,279
    • In genetics: 424
  • Year to date:
    • Site-wide: 25,028
  • Since beginning of last month:
    • Site-wide: 37,605

Local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits

genetics more details view paper
  • Downloaded 1,807 times
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    • Site-wide: 11,632
    • In genetics: 489
  • Year to date:
    • Site-wide: 10,682
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    • Site-wide: 24,887

A powerful approach to estimating annotation-stratified genetic covariance using GWAS summary statistics

genetics more details view paper
  • Downloaded 1,704 times
  • Download rankings, all-time:
    • Site-wide: 12,672
    • In genetics: 546
  • Year to date:
    • Site-wide: 85,260
  • Since beginning of last month:
    • Site-wide: 91,732

Neoantigen-driven B cell and CD4+ T follicular helper cell collaboration promotes robust anti-tumor CD8+ T cell responses

immunology more details view paper
  • Downloaded 1,539 times
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    • Site-wide: 14,789
    • In immunology: 514
  • Year to date:
    • Site-wide: 4,880
  • Since beginning of last month:
    • Site-wide: 12,296

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

genetic and genomic medicine more details view paper
  • Downloaded 1,413 times
  • Download rankings, all-time:
    • Site-wide: 16,947
    • In genetic and genomic medicine: 82
  • Year to date:
    • Site-wide: 6,067
  • Since beginning of last month:
    • Site-wide: 8,972

Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer's disease

genetics more details view paper
  • Downloaded 1,346 times
  • Download rankings, all-time:
    • Site-wide: 18,216
    • In genetics: 811
  • Year to date:
    • Site-wide: 152,125
  • Since beginning of last month:
    • Site-wide: 142,959

Genomic Characterization of Posttraumatic Stress Disorder in a Large US Military Veteran Sample

genetics more details view paper
  • Downloaded 1,327 times
  • Download rankings, all-time:
    • Site-wide: 18,604
    • In genetics: 832
  • Year to date:
    • Site-wide: 18,276
  • Since beginning of last month:
    • Site-wide: 53,585

SCRIBE: a new approach to dropout imputation and batch effects correction for single-cell RNA-seq data

bioinformatics more details view paper
  • Downloaded 1,222 times
  • Download rankings, all-time:
    • Site-wide: 21,085
    • In bioinformatics: 2,387
  • Year to date:
    • Site-wide: 62,142
  • Since beginning of last month:
    • Site-wide: 75,911

Measuring genetic variation in the multi-ethnic Million Veteran Program (MVP)

genetics more details view paper
  • Downloaded 1,124 times
  • Download rankings, all-time:
    • Site-wide: 23,954
    • In genetics: 1,045
  • Year to date:
    • Site-wide: 29,792
  • Since beginning of last month:
    • Site-wide: 39,886

Mediated pleiotropy between psychiatric disorders and autoimmune disorders revealed by integrative analysis of multiple GWAS

genomics more details view paper
  • Downloaded 1,033 times
  • Download rankings, all-time:
    • Site-wide: 27,241
    • In genomics: 2,428
  • Year to date:
    • Site-wide: 115,387
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    • Site-wide: 102,732

Leveraging functional annotation to identify genes associated with complex diseases

genetics more details view paper
  • Downloaded 1,020 times
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    • Site-wide: 27,734
    • In genetics: 1,218
  • Year to date:
    • Site-wide: 119,582
  • Since beginning of last month:
    • Site-wide: 138,148

Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424)

genetics more details view paper
  • Downloaded 966 times
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    • Site-wide: 30,050
    • In genetics: 1,321
  • Year to date:
    • Site-wide: 80,244
  • Since beginning of last month:
    • Site-wide: 120,903

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

genetic and genomic medicine more details view paper
  • Downloaded 911 times
  • Download rankings, all-time:
    • Site-wide: 32,721
    • In genetic and genomic medicine: 153
  • Year to date:
    • Site-wide: 6,224
  • Since beginning of last month:
    • Site-wide: 870

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

genetics more details view paper
  • Downloaded 865 times
  • Download rankings, all-time:
    • Site-wide: 35,282
    • In genetics: 1,547
  • Year to date:
    • Site-wide: 32,051
  • Since beginning of last month:
    • Site-wide: 41,252

Comparison of methods for estimating genetic correlation between complex traits using GWAS summary statistics

genetics more details view paper
  • Downloaded 840 times
  • Download rankings, all-time:
    • Site-wide: 36,819
    • In genetics: 1,609
  • Year to date:
    • Site-wide: 16,955
  • Since beginning of last month:
    • Site-wide: 31,253

Transcriptomic Organization of Human Posttraumatic Stress Disorder

genomics more details view paper
  • Downloaded 810 times
  • Download rankings, all-time:
    • Site-wide: 38,833
    • In genomics: 3,140
  • Year to date:
    • Site-wide: 64,440
  • Since beginning of last month:
    • Site-wide: 100,028

Leveraging Functional Annotations in Genetic Risk Prediction for Human Complex Diseases

bioinformatics more details view paper
  • Downloaded 782 times
  • Download rankings, all-time:
    • Site-wide: 40,781
    • In bioinformatics: 4,298
  • Year to date:
    • Site-wide: 149,596
  • Since beginning of last month:
    • Site-wide: 159,050

A fast and robust Bayesian nonparametric method for prediction of complex traits using summary statistics

bioinformatics more details view paper
  • Downloaded 739 times
  • Download rankings, all-time:
    • Site-wide: 44,267
    • In bioinformatics: 4,627
  • Year to date:
    • Site-wide: 13,405
  • Since beginning of last month:
    • Site-wide: 40,515

Influence of blood pressure on pneumonia risk: Epidemiological association and Mendelian randomisation in the UK Biobank

genetic and genomic medicine more details view paper
  • Downloaded 736 times
  • Download rankings, all-time:
    • Site-wide: 44,501
    • In genetic and genomic medicine: 208
  • Year to date:
    • Site-wide: 60,313
  • Since beginning of last month:
    • Site-wide: 56,326

Three distinct velocities of elongating RNA polymerase define exons and introns

genomics more details view paper
  • Downloaded 678 times
  • Download rankings, all-time:
    • Site-wide: 49,872
    • In genomics: 3,789
  • Year to date:
    • Site-wide: 129,433
  • Since beginning of last month:
    • Site-wide: 122,443

Application of a Novel Machine Learning Method to Big Data Infers a Relationship Between Asthma and the Development of Neoplasia

epidemiology more details view paper
  • Downloaded 641 times
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    • Site-wide: 53,822
    • In epidemiology: 2,560
  • Year to date:
    • Site-wide: 42,792
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    • Site-wide: 86,710

Identifying Combinations of Cancer Drivers in Individual Patients

bioinformatics more details view paper
  • Downloaded 636 times
  • Download rankings, all-time:
    • Site-wide: 54,413
    • In bioinformatics: 5,424
  • Year to date:
    • Site-wide: 109,174
  • Since beginning of last month:
    • Site-wide: 75,020

Genetic Association of Arterial Stiffness Index with Blood Pressure and Coronary Artery Disease

bioinformatics more details view paper
  • Downloaded 581 times
  • Download rankings, all-time:
    • Site-wide: 61,113
    • In bioinformatics: 5,966
  • Year to date:
    • Site-wide: 125,825
  • Since beginning of last month:
    • Site-wide: 145,944

Circadian Rhythm Analysis Using Wearable Device Data: A Novel Penalized Machine Learning Approach

neuroscience more details view paper
  • Downloaded 514 times
  • Download rankings, all-time:
    • Site-wide: 70,791
    • In neuroscience: 10,291
  • Year to date:
    • Site-wide: 47,293
  • Since beginning of last month:
    • Site-wide: 43,936

MR-APSS: a unified approach to Mendelian Randomization accounting for pleiotropy and sample structure using genome-wide summary statistics

genetics more details view paper
  • Downloaded 502 times
  • Download rankings, all-time:
    • Site-wide: 72,781
    • In genetics: 3,085
  • Year to date:
    • Site-wide: 15,826
  • Since beginning of last month:
    • Site-wide: 14,916

A Markov Random Field Model for Network-based Differential Expression Analysis of Single-cell RNA-seq Data

bioinformatics more details view paper
  • Downloaded 466 times
  • Download rankings, all-time:
    • Site-wide: 78,998
    • In bioinformatics: 7,204
  • Year to date:
    • Site-wide: 36,466
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    • Site-wide: 71,941

microRNA seedless sites attenuate strong-seed-site-mediated target repression

bioinformatics more details view paper
  • Downloaded 440 times
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    • Site-wide: 84,160
    • In bioinformatics: 7,561
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    • Site-wide: 93,504
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    • Site-wide: 65,460

Genomic Influences on Self-Reported Childhood Maltreatment

genomics more details view paper
  • Downloaded 406 times
  • Download rankings, all-time:
    • Site-wide: 91,071
    • In genomics: 5,730
  • Year to date:
    • Site-wide: 159,451
  • Since beginning of last month:
    • Site-wide: 159,121

A Statistical Framework to Identify Cell Types Whose Genetically Regulated Proportions are Associated with Complex Diseases

genetic and genomic medicine more details view paper
  • Downloaded 401 times
  • Download rankings, all-time:
    • Site-wide: 91,999
    • In genetic and genomic medicine: 475
  • Year to date:
    • Site-wide: 22,407
  • Since beginning of last month:
    • Site-wide: 35,990

Non-linear Archetypal Analysis of Single-cell RNA-seq Data by Deep Autoencoders

bioinformatics more details view paper
  • Downloaded 391 times
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    • Site-wide: 94,382
    • In bioinformatics: 8,236
  • Year to date:
    • Site-wide: 23,344
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    • Site-wide: 15,363

Identifying Modules of Cooperating Cancer Drivers

cancer biology more details view paper
  • Downloaded 390 times
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    • Site-wide: 94,563
    • In cancer biology: 2,830
  • Year to date:
    • Site-wide: 76,569
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    • Site-wide: 58,948

Motor nuclei innervating eye muscles spared in mouse model of SOD1-linked ALS

neuroscience more details view paper
  • Downloaded 368 times
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    • Site-wide: 99,574
    • In neuroscience: 14,821
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    • Site-wide: 119,209
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    • Site-wide: 92,241

Retrospective Association Analysis of Longitudinal Binary Traits Identifies Important Loci and Pathways in Cocaine Use

genetics more details view paper
  • Downloaded 368 times
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    • Site-wide: 99,582
    • In genetics: 4,117
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    • Site-wide: 145,547
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    • Site-wide: 152,746

Comprehensive Analysis of Ubiquitously Expressed Genes in Human, From a Data-Driven Perspective

genomics more details view paper
  • Downloaded 338 times
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    • Site-wide: 106,748
    • In genomics: 6,303
  • Year to date:
    • Site-wide: 28,912
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    • Site-wide: 5,569

TP53-mediated clonal hematopoiesis confers increased risk for incident peripheral artery disease

genetic and genomic medicine more details view paper
  • Downloaded 326 times
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    • Site-wide: 109,771
    • In genetic and genomic medicine: 599
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    • Site-wide: 30,522
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    • Site-wide: 22,862

TRPV5, TRPV6, TRPM6, and TRPM7 do not contribute to hair-cell mechanotransduction

neuroscience more details view paper
  • Downloaded 325 times
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    • Site-wide: 110,189
    • In neuroscience: 16,493
  • Year to date:
    • Site-wide: 133,830
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    • Site-wide: 127,702

Inferring time-lagged causality using the derivative of single-cell expression

bioinformatics more details view paper
  • Downloaded 288 times
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    • Site-wide: 119,732
    • In bioinformatics: 9,762
  • Year to date:
    • Site-wide: 36,319
  • Since beginning of last month:
    • Site-wide: 77,015

Quantifying concordant genetic effects of de novo mutations on multiple disorders

genetics more details view paper
  • Downloaded 280 times
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    • Site-wide: 121,813
    • In genetics: 4,936
  • Year to date:
    • Site-wide: 37,684
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    • Site-wide: 21,523

Integrative Analyses Reveal Novel Disease-associated Loci and Genes for Idiopathic Pulmonary Fibrosis

genetic and genomic medicine more details view paper
  • Downloaded 266 times
  • Download rankings, all-time:
    • Site-wide: 125,482
    • In genetic and genomic medicine: 724
  • Year to date:
    • Site-wide: 40,449
  • Since beginning of last month:
    • Site-wide: 32,771

M-DATA: A Statistical Approach to Jointly Analyzing De Novo Mutations for Multiple Traits

genetic and genomic medicine more details view paper
  • Downloaded 258 times
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    • Site-wide: 127,676
    • In genetic and genomic medicine: 735
  • Year to date:
    • Site-wide: 42,234
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    • Site-wide: 27,911

Correcting statistical bias in correlation-based kinship estimators

genetics more details view paper
  • Downloaded 247 times
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    • Site-wide: 130,524
    • In genetics: 5,238
  • Year to date:
    • Site-wide: 44,647
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    • Site-wide: 54,354

Automated Feature Extraction from Population Wearable Device Data Identified Novel Loci Associated with Sleep and Circadian Rhythms

genetics more details view paper
  • Downloaded 232 times
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    • Site-wide: 134,349
    • In genetics: 5,368
  • Year to date:
    • Site-wide: 136,468
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    • Site-wide: 158,296

Hemodynamic Differences Between Women and Men with Elevated Blood Pressure in China

cardiovascular medicine more details view paper
  • Downloaded 199 times
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    • Site-wide: 142,647
    • In cardiovascular medicine: 444
  • Year to date:
    • Site-wide: 58,563
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    • Site-wide: 57,682

Estimating genetic correlation jointly using individual-level and summary-level GWAS data

genetics more details view paper
  • Downloaded 155 times
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    • Site-wide: 152,107
    • In genetics: 5,912
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    • Site-wide: 77,347
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    • Site-wide: 63,828

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