Author: Chen Wang

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Preprints

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

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  • Site-wide: 465
  • In molecular biology: 5
• Year to date:
  • Site-wide: 1,637
• Since beginning of last month:
  • Site-wide: 6,071

Single-cell profiles of retinal neurons differing in resilience to injury reveal neuroprotective genes

• Downloaded 3,487 times
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  • Site-wide: 4,215
  • In neuroscience: 334
• Year to date:
  • Site-wide: 6,625
• Since beginning of last month:
  • Site-wide: 9,002

PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins

• Downloaded 1,957 times
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  • Site-wide: 9,714
  • In neuroscience: 967
• Year to date:
  • Site-wide: 46,492
• Since beginning of last month:
  • Site-wide: 73,965

Stress induces dynamic, cytotoxicity-antagonizing TDP-43 nuclear bodies via paraspeckle lncRNA NEAT1-mediated liquid-liquid phase separation

• Downloaded 1,874 times
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  • Site-wide: 10,374
  • In neuroscience: 1,051
• Year to date:
  • Site-wide: 9,518
• Since beginning of last month:
  • Site-wide: 21,134

Comprehensive cross-population analysis of high-grade serous ovarian cancer supports no more than three subtypes

• Downloaded 1,480 times
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  • Site-wide: 14,765
  • In cancer biology: 312
• Year to date:
  • Site-wide: 97,447
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  • Site-wide: 148,472

Use of FFPE-Derived DNA in Next Generation Sequencing: DNA extraction methods

• Downloaded 1,131 times
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  • Site-wide: 22,093
  • In molecular biology: 579
• Year to date:
  • Site-wide: 51,246
• Since beginning of last month:
  • Site-wide: 74,165

COVID-19 and climate: global evidence from 117 countries

• Downloaded 1,069 times
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  • Site-wide: 24,008
  • In public and global health: 460
• Year to date:
  • Site-wide: 29,986
• Since beginning of last month:
  • Site-wide: 41,914

An atlas of Caenorhabditis elegans chemoreceptor expression

• Downloaded 957 times
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  • Site-wide: 28,262
  • In genetics: 1,265
• Year to date:
  • Site-wide: 53,160
• Since beginning of last month:
  • Site-wide: 88,560

Individualized ctDNA Fingerprints to Monitor Treatment Response and Recurrence in Multiple Cancer Types

• Downloaded 873 times
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  • Site-wide: 32,247
  • In cancer biology: 853
• Year to date:
  • Site-wide: 46,575
• Since beginning of last month:
  • Site-wide: 36,516

An Array of 60,000 Antibodies for Proteome-Scale Antibody Generation and Target Discovery

• Downloaded 807 times
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  • Site-wide: 35,999
  • In systems biology: 751
• Year to date:
  • Site-wide: 113,556
• Since beginning of last month:
  • Site-wide: 104,249

Pathogenicity, tissue tropism and potential vertical transmission of SARSr-CoV-2 in Malayan pangolins

• Downloaded 755 times
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  • Site-wide: 39,564
  • In microbiology: 2,375
• Year to date:
  • Site-wide: 37,500
• Since beginning of last month:
  • Site-wide: 66,090

Neuronal mitochondria transport Pink1 mRNA via Synaptojanin 2 to support local mitophagy

• Downloaded 737 times
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  • Site-wide: 40,869
  • In neuroscience: 5,533
• Year to date:
  • Site-wide: 6,915
• Since beginning of last month:
  • Site-wide: 19,094

Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

• Downloaded 693 times
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  • Site-wide: 44,449
  • In genomics: 3,503
• Year to date:
  • Site-wide: 99,660
• Since beginning of last month:
  • Site-wide: 87,690

Timing mechanism of sexually dimorphic nervous system differentiation

• Downloaded 535 times
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  • Site-wide: 61,729
  • In neuroscience: 8,914
• Year to date:
  • Site-wide: 138,475
• Since beginning of last month:
  • Site-wide: 112,734

Direct medical costs of hospitalized patients with idiopathic pulmonary fibrosis in China

• Downloaded 509 times
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  • Site-wide: 65,330
  • In health economics: 93
• Year to date:
  • Site-wide: 70,001
• Since beginning of last month:
  • Site-wide: 72,415

Chansu Injection Improves the Respiratory Function of Severe COVID-19 Patients

• Downloaded 460 times
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  • Site-wide: 73,133
  • In infectious diseases: 3,847
• Year to date:
  • Site-wide: 82,172
• Since beginning of last month:
  • Site-wide: 52,874

Hsp70 chaperons TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation

• Downloaded 452 times
• Download rankings, all-time:
  • Site-wide: 74,429
  • In cell biology: 3,360
• Year to date:
  • Site-wide: 19,677
• Since beginning of last month:
  • Site-wide: 34,317

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

• Downloaded 439 times
• Download rankings, all-time:
  • Site-wide: 76,829
  • In genetics: 3,290
• Year to date:
  • Site-wide: 14,979
• Since beginning of last month:
  • Site-wide: 58,032

Transcriptome analysis of potato leaves in response to infection with the necrotrophic pathogen Alternaria solani

• Downloaded 304 times
• Download rankings, all-time:
  • Site-wide: 105,853
  • In plant biology: 2,852
• Year to date:
  • Site-wide: 51,624
• Since beginning of last month:
  • Site-wide: 84,655

Efficient Proximal Gradient Algorithm for Inference of Differential Gene Networks

• Downloaded 302 times
• Download rankings, all-time:
  • Site-wide: 106,328
  • In bioinformatics: 8,970
• Year to date:
  • Site-wide: 158,689
• Since beginning of last month:
  • Site-wide: 154,625

Effects of CXCL12/CXCR4/CXCR7 axis on human sperm motility and chemotaxis

• Downloaded 298 times
• Download rankings, all-time:
  • Site-wide: 107,191
  • In cell biology: 5,000
• Year to date:
  • Site-wide: 107,304
• Since beginning of last month:
  • Site-wide: 69,498

Coverage profile correction of shallow-depth circulating cell free DNA sequencing via multi-distance learning

• Downloaded 294 times
• Download rankings, all-time:
  • Site-wide: 108,192
  • In bioinformatics: 9,093
• Year to date:
  • Site-wide: 146,211
• Since beginning of last month:
  • Site-wide: 113,084

Cerebrospinal fluids from healthy pregnant women does not harbor a detectable microbial community

• Downloaded 254 times
• Download rankings, all-time:
  • Site-wide: 118,501
  • In microbiology: 8,542
• Year to date:
  • Site-wide: 65,677
• Since beginning of last month:
  • Site-wide: 53,162

Volatile molecules secreted by the wheat pathogen Parastagonospora nodorum are involved in development and phytotoxicity

• Downloaded 235 times
• Download rankings, all-time:
  • Site-wide: 123,449
  • In microbiology: 8,988
• Year to date:
  • Site-wide: 155,644
• Since beginning of last month:
  • Site-wide: 153,915

Familial prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM

• Downloaded 209 times
• Download rankings, all-time:
  • Site-wide: 130,260
  • In biochemistry: 3,946
• Year to date:
  • Site-wide: 41,536
• Since beginning of last month:
  • Site-wide: 58,838

Dynamics of glioma-associated microglia and macrophages reveals their divergent roles in the immune response of brain

• Downloaded 196 times
• Download rankings, all-time:
  • Site-wide: 133,578
  • In immunology: 3,986
• Year to date:
  • Site-wide: 44,630
• Since beginning of last month:
  • Site-wide: 54,160

Establishment and characterization of fibroblast cultures derived from a female common hippopotamus (Hippopotamus amphibius) skin biopsy

• Downloaded 187 times
• Download rankings, all-time:
  • Site-wide: 135,656
  • In cell biology: 6,292
• Year to date:
  • Site-wide: 80,376
• Since beginning of last month:
  • Site-wide: 47,043

Powerful gene-based testing by integrating long-range chromatin interactions and knockoff genotypes

• Downloaded 181 times
• Download rankings, all-time:
  • Site-wide: 137,177
  • In genetic and genomic medicine: 778
• Year to date:
  • Site-wide: 49,035
• Since beginning of last month:
  • Site-wide: 29,560

Repetitive and Brief Occlusion of the Majority of the Vena Cava Flow Attenuates Pulmonary Arterial Hypertension and Improves IK+ of the Pulmonary Arterial Smooth Muscle Cells in Rat Models: a novel potential therapeutic strategy for PAH

• Downloaded 132 times
• Download rankings, all-time:
  • Site-wide: 148,071
  • In pathology: 903
• Year to date:
  • Site-wide: 135,632
• Since beginning of last month:
  • Site-wide: 98,893

Glucose Production and Glucose Disposal Integrated by an Intrinsic Inverse Coupling in Vivo: hypothesis of inter-organ reflex on glucose regulation

• Downloaded 125 times
• Download rankings, all-time:
  • Site-wide: 149,407
  • In physiology: 1,803
• Year to date:
  • Site-wide: 154,216
• Since beginning of last month:
  • Site-wide: 133,733

A meta-analysis of Microarray Data is Effective for Identifying Gravity-Sensitive Genes

• Downloaded 98 times
• Download rankings, all-time:
  • Site-wide: 153,821
  • In cell biology: 7,019
• Year to date:
  • Site-wide: 88,981
• Since beginning of last month:
  • Site-wide: 32,438