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Author: Michael J. Owen

  • ORCiD: http://orcid.org/0000-0003-4798-0862
  • Most recently observed institution: MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University

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    • genomics: 10,682 (rank: 1,489 out of 44,673)
    • neuroscience: 3,103 (rank: 5,363 (tie) out of 72,420)

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Preprints

Developmental profile of psychiatric risk associated with voltage-gated cation channel activity

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Genomewide association study identifies 30 loci associated with bipolar disorder

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Genetic Identification Of Brain Cell Types Underlying Schizophrenia

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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

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Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

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Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

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Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank

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Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

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Rare schizophrenia risk variants are enriched in genes shared with neurodevelopmental disorders

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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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Genetic association study of psychotic experiences in UK Biobank

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Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

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Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

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Different complement immune pathways mediate innate and learned aversion

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Analyses of rare and common alleles in parent-proband trios implicate rare missense variants in SLC6A1 in schizophrenia and confirm the involvement of loss of function intolerant and neurodevelopmental disorder genes.

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Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders

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Dynamic expression of risk genes for schizophrenia and bipolar disorder across development

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Haploinsufficiency of the psychiatric risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms

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Genetic association of FMRP targets with psychiatric disorders

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Cyfip1 haploinsufficiency is associated with white matter changes, myelin thinning, reduction of mature oligodendrocytes and behavioural inflexibility

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The role of rare copy number variants in depression

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Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

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Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

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Meta-analysis of Scandinavian Schizophrenia Exomes

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Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

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Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

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The rate of de novo CNVs in healthy controls

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Electrophysiological network alterations in adults with copy number variants associated with high neurodevelopmental risk

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Effects of pathogenic CNVs on biochemical markers: a study on the UK Biobank

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Coordination difficulties, IQ and psychopathology in children with high-risk Copy Number Variants

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Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

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