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Author: Michael J Owen

  • ORCiD: http://orcid.org/0000-0003-4798-0862
  • Most recently observed institution: Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, GB

Rankings

  • All-time downloads: 55,839 (rank: 2,463 )
  • Categories:
    • genetic and genomic medicine: 5,470 (rank: 114 )
    • genetics: 31,933 (rank: 174 )
    • genomics: 11,042 (rank: 1,629 )
    • neuroscience: 3,816 (rank: 5,191 )
    • pharmacology and therapeutics: 180 (rank: 721 (tie) )
    • psychiatry and clinical psychology: 3,398 (rank: 107 )

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
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    • Site-wide: 868
    • In genetics: 26
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    • Site-wide: 31,048
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Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 7,323 times
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    • Site-wide: 1,202
    • In genetics: 38
  • Year to date:
    • Site-wide: 18,311
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    • Site-wide: 17,741

Genetic Identification Of Brain Cell Types Underlying Schizophrenia

genomics more details view paper
  • Downloaded 3,600 times
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    • Site-wide: 3,188
    • In genomics: 361
  • Year to date:
    • Site-wide: 71,327
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    • Site-wide: 55,249

Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 3,367 times
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    • Site-wide: 3,506
    • In genetic and genomic medicine: 11
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    • Site-wide: 1,001

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
  • Downloaded 2,511 times
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    • Site-wide: 5,331
    • In genomics: 603
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Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

genetics more details view paper
  • Downloaded 2,269 times
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    • Site-wide: 6,212
    • In genetics: 295
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    • Site-wide: 8,319
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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
  • Downloaded 2,120 times
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    • Site-wide: 6,853
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    • Site-wide: 1,372
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,787 times
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    • Site-wide: 8,837
    • In genetics: 417
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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
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    • Site-wide: 11,434
    • In genetics: 550
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,458 times
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    • In genomics: 1,297
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Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

genetics more details view paper
  • Downloaded 1,132 times
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    • In genetics: 852
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    • Site-wide: 50,019
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    • Site-wide: 72,686

Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank

genomics more details view paper
  • Downloaded 1,044 times
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    • Site-wide: 19,717
    • In genomics: 1,987
  • Year to date:
    • Site-wide: 115,477
  • Since beginning of last month:
    • Site-wide: 131,516

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

genomics more details view paper
  • Downloaded 1,023 times
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    • Site-wide: 20,284
    • In genomics: 2,030
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    • Site-wide: 90,487
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Rare schizophrenia risk variants are enriched in genes shared with neurodevelopmental disorders

genetics more details view paper
  • Downloaded 999 times
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    • Site-wide: 20,985
    • In genetics: 1,005
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    • Site-wide: 101,409
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    • Site-wide: 78,614

A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants

psychiatry and clinical psychology more details view paper
  • Downloaded 874 times
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    • Site-wide: 25,487
    • In psychiatry and clinical psychology: 85
  • Year to date:
    • Site-wide: 6,815
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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

genetics more details view paper
  • Downloaded 843 times
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    • Site-wide: 26,768
    • In genetics: 1,293
  • Year to date:
    • Site-wide: 76,905
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    • Site-wide: 73,113

Genetic association study of psychotic experiences in UK Biobank

genetics more details view paper
  • Downloaded 806 times
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    • Site-wide: 28,467
    • In genetics: 1,381
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    • Site-wide: 46,430
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    • Site-wide: 35,808

Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders

genetics more details view paper
  • Downloaded 762 times
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    • Site-wide: 30,867
    • In genetics: 1,492
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    • Site-wide: 9,457
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Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

genetics more details view paper
  • Downloaded 760 times
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    • Site-wide: 54,311
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Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

genetics more details view paper
  • Downloaded 749 times
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    • Site-wide: 31,599
    • In genetics: 1,527
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    • Site-wide: 93,948
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Different complement immune pathways mediate innate and learned aversion

neuroscience more details view paper
  • Downloaded 746 times
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    • In neuroscience: 4,337
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    • Site-wide: 24,872
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    • Site-wide: 29,927

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

genetics more details view paper
  • Downloaded 711 times
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    • Site-wide: 33,855
    • In genetics: 1,640
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    • Site-wide: 79,691
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    • Site-wide: 71,904

A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

genetics more details view paper
  • Downloaded 638 times
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    • Site-wide: 39,159
    • In genetics: 1,864
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    • Site-wide: 88,120
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Analyses of rare and common alleles in parent-proband trios implicate rare missense variants in SLC6A1 in schizophrenia and confirm the involvement of loss of function intolerant and neurodevelopmental disorder genes.

genetics more details view paper
  • Downloaded 586 times
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    • Site-wide: 43,588
    • In genetics: 2,047
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    • Site-wide: 72,663

Genetic association of FMRP targets with psychiatric disorders

neuroscience more details view paper
  • Downloaded 556 times
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    • Site-wide: 46,559
    • In neuroscience: 6,772
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    • Site-wide: 41,591
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    • Site-wide: 50,726

The general impact of haploinsufficiency on brain connectivity underlies the pleiotropic effect of neuropsychiatric CNVs

genetic and genomic medicine more details view paper
  • Downloaded 546 times
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    • Site-wide: 47,548
    • In genetic and genomic medicine: 146
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    • Site-wide: 53,586
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    • Site-wide: 50,700

Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

genetics more details view paper
  • Downloaded 532 times
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    • Site-wide: 49,066
    • In genetics: 2,295
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    • Site-wide: 30,230
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    • Site-wide: 46,315

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

genetic and genomic medicine more details view paper
  • Downloaded 502 times
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    • Site-wide: 52,473
    • In genetic and genomic medicine: 167
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    • Site-wide: 11,112
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    • Site-wide: 10,002

Haploinsufficiency of the psychiatric risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms

neuroscience more details view paper
  • Downloaded 501 times
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    • Site-wide: 52,652
    • In neuroscience: 7,784
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    • Site-wide: 54,066
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Dynamic expression of risk genes for schizophrenia and bipolar disorder across development

neuroscience more details view paper
  • Downloaded 488 times
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    • Site-wide: 54,217
    • In neuroscience: 8,058
  • Year to date:
    • Site-wide: 115,072
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    • Site-wide: 128,276

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

genetics more details view paper
  • Downloaded 466 times
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    • Site-wide: 57,068
    • In genetics: 2,660
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    • Site-wide: 55,268

The role of rare copy number variants in depression

neuroscience more details view paper
  • Downloaded 458 times
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    • Site-wide: 58,119
    • In neuroscience: 8,687
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    • Site-wide: 79,880
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    • Site-wide: 103,942

Meta-analysis of Scandinavian Schizophrenia Exomes

genetics more details view paper
  • Downloaded 447 times
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    • Site-wide: 59,594
    • In genetics: 2,767
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    • Site-wide: 59,804
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    • Site-wide: 81,897

Neuropsychiatric copy number variants exert shared effects on human brain structure

genetic and genomic medicine more details view paper
  • Downloaded 436 times
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    • Site-wide: 61,250
    • In genetic and genomic medicine: 195
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    • Site-wide: 38,353
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    • Site-wide: 43,773

Cyfip1 haploinsufficiency is associated with white matter changes, myelin thinning, reduction of mature oligodendrocytes and behavioural inflexibility

neuroscience more details view paper
  • Downloaded 435 times
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    • Site-wide: 61,354
    • In neuroscience: 9,208
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    • Site-wide: 119,099
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    • Site-wide: 111,972

Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

genomics more details view paper
  • Downloaded 399 times
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    • Site-wide: 66,906
    • In genomics: 4,731
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    • Site-wide: 123,015
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    • Site-wide: 90,679

Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 381 times
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    • Site-wide: 69,792
    • In genetic and genomic medicine: 231
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    • Site-wide: 4,302
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    • Site-wide: 1,215

Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

genomics more details view paper
  • Downloaded 364 times
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    • Site-wide: 72,762
    • In genomics: 5,001
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The rate of de novo CNVs in healthy controls

genomics more details view paper
  • Downloaded 346 times
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Electrophysiological network alterations in adults with copy number variants associated with high neurodevelopmental risk

neuroscience more details view paper
  • Downloaded 312 times
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    • Site-wide: 82,618
    • In neuroscience: 12,700
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Effects of pathogenic CNVs on biochemical markers: a study on the UK Biobank

genomics more details view paper
  • Downloaded 297 times
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    • In genomics: 5,477
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Emotional and behavioural phenotypes in young people with neurodevelopmental CNVs

psychiatry and clinical psychology more details view paper
  • Downloaded 290 times
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    • Site-wide: 87,307
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A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder

genetic and genomic medicine more details view paper
  • Downloaded 238 times
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    • Site-wide: 98,609
    • In genetic and genomic medicine: 389
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Coordination difficulties, IQ and psychopathology in children with high-risk Copy Number Variants

genetics more details view paper
  • Downloaded 234 times
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    • Site-wide: 99,586
    • In genetics: 4,431
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Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

neuroscience more details view paper
  • Downloaded 216 times
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    • Site-wide: 103,402
    • In neuroscience: 16,040
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    • Site-wide: 61,932
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    • Site-wide: 81,399

Clozapine metabolism is associated with Absolute Neutrophil Count in individuals with treatment-resistant schizophrenia

pharmacology and therapeutics more details view paper
  • Downloaded 180 times
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    • Site-wide: 111,482
    • In pharmacology and therapeutics: 96
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    • Site-wide: 12,454
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    • Site-wide: 8,728

Psychopathology in mothers of children with pathogenic Copy Number Variants

psychiatry and clinical psychology more details view paper
  • Downloaded 114 times
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    • Site-wide: 124,796
    • In psychiatry and clinical psychology: 598
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Developmental profile of psychiatric risk associated with voltage-gated cation channel activity

neuroscience more details view paper
  • Downloaded 104 times
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    • Site-wide: 126,605
    • In neuroscience: 19,425
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