Author: Roy H Perlis

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Preprints

Single cell profiling of Hofbauer cells and fetal brain microglia reveals shared programs and functions

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Genomewide association study identifies 30 loci associated with bipolar disorder

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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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Minimal phenotyping yields GWAS hits of reduced specificity for major depression

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Identifying common pharmacotherapies associated with reduced COVID-19 morbidity using electronic health records

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Increased microglial synapse elimination in patient-specific models of schizophrenia

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Impact of COVID-19 on psychiatric assessment in emergency and outpatient settings measured using electronic health records

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Persistence of symptoms up to 10 months following acute COVID-19 illness

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Laboratory findings associated with mechanical ventilation requirement and mortality among hospitalized individuals with Covid-19 in Eastern Massachusetts

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Estimated regional white matter hyperintensity burden, resting state functional connectivity, and cognitive functions in older adults

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New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

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Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

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Frequency and profile of objective cognitive deficits in hospitalized patients recovering from COVID-19

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Comparison of post-COVID depression and major depressive disorder

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Umbilical cord blood derived microglia-like cells to model COVID-19 exposure

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SARS-CoV-2 Neurotropism and Single Cell Responses in Brain Organoids Containing Innately Developing Microglia

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N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells

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Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records

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Generating interpretable predictions about antidepressant treatment stability using supervised topic models

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Novel polygenic risk score links depression-related cortical transcriptomic changes to brain morphology and symptom severity

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Case-control study of neuropsychiatric symptoms following COVID-19 hospitalization in 2 academic health systems

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Persistence of neuropsychiatric symptoms associated with SARS-CoV-2 positivity among a cohort of children and adolescents

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Consistency of performance of adverse outcome prediction models for hospitalized COVID-19 patients

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Cerebrospinal fluid concentration of complement component 4A is increased in first-episode schizophrenia

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Association between social media use and self-reported symptoms of depression in US adults

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