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Author: Sudha Seshadri

Rankings

  • All-time downloads: 50,130 (rank: 4,786 )
  • Categories:
    • bioinformatics: 813 (rank: 22,509 (tie) )
    • epidemiology: 2,554 (rank: 6,428 )
    • genetic and genomic medicine: 5,879 (rank: 372 (tie) )
    • genetics: 16,960 (rank: 958 )
    • genomics: 9,713 (rank: 2,391 )
    • hematology: 1,077 (rank: 399 (tie) )
    • neurology: 6,824 (rank: 233 )
    • neuroscience: 3,439 (rank: 8,397 )

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Preprints

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

genomics more details view paper
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    • Site-wide: 1,443
    • In genomics: 92
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    • Site-wide: 12,466
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    • Site-wide: 18,430

The genetic architecture of the human cerebral cortex

genetics more details view paper
  • Downloaded 8,426 times
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    • Site-wide: 1,582
    • In genetics: 35
  • Year to date:
    • Site-wide: 24,318
  • Since beginning of last month:
    • Site-wide: 29,667

New insights on the genetic etiology of Alzheimer and related dementia

neurology more details view paper
  • Downloaded 7,159 times
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    • Site-wide: 1,940
    • In neurology: 7
  • Year to date:
    • Site-wide: 1,301
  • Since beginning of last month:
    • Site-wide: 4,205

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

genetics more details view paper
  • Downloaded 3,455 times
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    • Site-wide: 5,310
    • In genetics: 172
  • Year to date:
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Common variants in Alzheimer's disease: Novel association of six genetic variants with AD and risk stratification by polygenic risk scores

genetic and genomic medicine more details view paper
  • Downloaded 3,102 times
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    • Site-wide: 6,217
    • In genetic and genomic medicine: 28
  • Year to date:
    • Site-wide: 29,401
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    • Site-wide: 37,975

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimers Disease

genetic and genomic medicine more details view paper
  • Downloaded 2,454 times
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    • Site-wide: 8,746
    • In genetic and genomic medicine: 45
  • Year to date:
    • Site-wide: 3,302
  • Since beginning of last month:
    • Site-wide: 8,024

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

neuroscience more details view paper
  • Downloaded 2,035 times
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    • Site-wide: 11,590
    • In neuroscience: 1,084
  • Year to date:
    • Site-wide: 89,532
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    • Site-wide: 66,592

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

genetics more details view paper
  • Downloaded 1,861 times
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    • Site-wide: 13,190
    • In genetics: 498
  • Year to date:
    • Site-wide: 125,439
  • Since beginning of last month:
    • Site-wide: 117,114

Clonal hematopoiesis is associated with protection from Alzheimer's disease

hematology more details view paper
  • Downloaded 1,521 times
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    • Site-wide: 17,916
    • In hematology: 24
  • Year to date:
    • Site-wide: 1,832
  • Since beginning of last month:
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Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design

epidemiology more details view paper
  • Downloaded 1,481 times
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    • Site-wide: 18,610
    • In epidemiology: 1,350
  • Year to date:
    • Site-wide: 9,822
  • Since beginning of last month:
    • Site-wide: 8,566

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants

genetics more details view paper
  • Downloaded 1,005 times
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    • Site-wide: 33,780
    • In genetics: 1,428
  • Year to date:
    • Site-wide: 65,847
  • Since beginning of last month:
    • Site-wide: 26,339

Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer's Disease Sequencing Project

genetics more details view paper
  • Downloaded 970 times
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    • Site-wide: 35,576
    • In genetics: 1,400
  • Year to date:
    • Site-wide: 183,533
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    • Site-wide: 178,480

Planar cell polarity pathway and development of the human visual cortex

neuroscience more details view paper
  • Downloaded 952 times
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    • Site-wide: 36,625
    • In neuroscience: 4,615
  • Year to date:
    • Site-wide: 76,854
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    • Site-wide: 51,505

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

genetics more details view paper
  • Downloaded 916 times
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    • Site-wide: 38,791
    • In genetics: 1,539
  • Year to date:
    • Site-wide: 137,048
  • Since beginning of last month:
    • Site-wide: 119,604

Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

bioinformatics more details view paper
  • Downloaded 841 times
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    • Site-wide: 44,021
    • In bioinformatics: 4,362
  • Year to date:
    • Site-wide: 114,467
  • Since beginning of last month:
    • Site-wide: 71,972

Genome-Wide Meta-Analysis of Late-Onset Alzheimer's Disease Using Rare Variant Imputation in 324,809 Subjects Identifies Novel Rare Variant Locus NCK2: The International Genomics of Alzheimer's Project (IGAP)

genetic and genomic medicine more details view paper
  • Downloaded 791 times
  • Download rankings, all-time:
    • Site-wide: 48,179
    • In genetic and genomic medicine: 295
  • Year to date:
    • Site-wide: 19,072
  • Since beginning of last month:
    • Site-wide: 15,427

Genetic variants for head size share genes and pathways with cancer

genomics more details view paper
  • Downloaded 676 times
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    • Site-wide: 60,197
    • In genomics: 4,449
  • Year to date:
    • Site-wide: 49,222
  • Since beginning of last month:
    • Site-wide: 54,215

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

genetics more details view paper
  • Downloaded 639 times
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    • Site-wide: 64,767
    • In genetics: 2,500
  • Year to date:
    • Site-wide: 147,681
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    • Site-wide: 104,036

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

epidemiology more details view paper
  • Downloaded 569 times
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    • Site-wide: 75,019
    • In epidemiology: 3,187
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    • Site-wide: 166,995
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    • Site-wide: 176,578

Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensities

neuroscience more details view paper
  • Downloaded 539 times
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    • Site-wide: 80,214
    • In neuroscience: 10,841
  • Year to date:
    • Site-wide: 169,042
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    • Site-wide: 173,106

Association of mitochondrial DNA copy number with cardiometabolic diseases in a large cross-sectional study of multiple ancestries

epidemiology more details view paper
  • Downloaded 475 times
  • Download rankings, all-time:
    • Site-wide: 92,898
    • In epidemiology: 3,923
  • Year to date:
    • Site-wide: 98,340
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    • Site-wide: 96,404

Immune system and blood-brain barrier-wide biomarker analyses provide causal evidence for autoimmunity in dementia

epidemiology more details view paper
  • Downloaded 456 times
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    • Site-wide: 97,195
    • In epidemiology: 5,802
  • Year to date:
    • Site-wide: 5,747
  • Since beginning of last month:
    • Site-wide: 28,118

Circulating interleukin-6 levels and incident ischemic stroke: a systematic review and meta-analysis of population-based cohort studies

neurology more details view paper
  • Downloaded 292 times
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    • Site-wide: 140,657
    • In neurology: 853
  • Year to date:
    • Site-wide: 43,589
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    • Site-wide: 23,947

RNA-sequencing of human post-mortem hypothalamus and nucleus accumbens identifies expression profiles associated with obesity.

genomics more details view paper
  • Downloaded 278 times
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    • Site-wide: 144,763
    • In genomics: 7,708
  • Year to date:
    • Site-wide: 12,165
  • Since beginning of last month:
    • Site-wide: 70,138

Polygenic resilience scores capture protective genetic effects for Alzheimers disease

genetic and genomic medicine more details view paper
  • Downloaded 199 times
  • Download rankings, all-time:
    • Site-wide: 167,149
    • In genetic and genomic medicine: None
  • Year to date:
    • Site-wide: 19,858
  • Since beginning of last month:
    • Site-wide: 2,762

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