Author: Olav B. Smeland

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Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

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  • Site-wide: 1,549
  • In genetics: 41
• Year to date:
  • Site-wide: 31,086
• Since beginning of last month:
  • Site-wide: 115,891

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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  • Site-wide: 2,354
  • In genetics: 70
• Year to date:
  • Site-wide: 22,774
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  • Site-wide: 31,171

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

• Downloaded 3,282 times
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  • Site-wide: 4,825
  • In genomics: 477
• Year to date:
  • Site-wide: 42,984
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  • Site-wide: 60,361

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

• Downloaded 3,121 times
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  • Site-wide: 5,180
  • In psychiatry and clinical psychology: 20
• Year to date:
  • Site-wide: 2,173
• Since beginning of last month:
  • Site-wide: 8,531

Genetics of brain age suggest an overlap with common brain disorders

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  • Site-wide: 5,666
  • In neuroscience: 481
• Year to date:
  • Site-wide: 42,993
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  • Site-wide: 49,499

Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness

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  • Site-wide: 8,519
  • In genomics: 851
• Year to date:
  • Site-wide: 15,739
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  • Site-wide: 59,490

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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  • Site-wide: 11,660
  • In genetics: 493
• Year to date:
  • Site-wide: 4,327
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  • Site-wide: 4,107

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 15,279
  • In genomics: 1,494
• Year to date:
  • Site-wide: 128,997
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  • Site-wide: 140,001

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

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  • Site-wide: 18,943
  • In genetics: 845
• Year to date:
  • Site-wide: 125,224
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  • Site-wide: 137,373

Phenotypically independent mental health symptom profiles are genetically related

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  • Site-wide: 30,428
  • In psychiatry and clinical psychology: 117
• Year to date:
  • Site-wide: 28,266
• Since beginning of last month:
  • Site-wide: 78,033

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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  • Site-wide: 32,085
  • In genetics: 1,407
• Year to date:
  • Site-wide: 106,280
• Since beginning of last month:
  • Site-wide: 95,038

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

• Downloaded 820 times
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  • Site-wide: 38,132
  • In genetic and genomic medicine: 179
• Year to date:
  • Site-wide: 15,128
• Since beginning of last month:
  • Site-wide: 23,098

Making the MOSTest of imaging genetics

• Downloaded 751 times
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  • Site-wide: 43,269
  • In neuroscience: 5,900
• Year to date:
  • Site-wide: 118,291
• Since beginning of last month:
  • Site-wide: 137,760

Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits

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  • Site-wide: 47,123
  • In neuroscience: 6,516
• Year to date:
  • Site-wide: 132,640
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  • Site-wide: 106,271

Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

• Downloaded 627 times
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  • Site-wide: 55,394
  • In genetics: 2,350
• Year to date:
  • Site-wide: 29,799
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  • Site-wide: 57,286

The dark side of the mean: brain structural heterogeneity in schizophrenia and its polygenic risk.

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  • Site-wide: 60,695
  • In neuroscience: 8,708
• Year to date:
  • Site-wide: 135,252
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  • Site-wide: 101,749

Genetic control of variability in subcortical and intracranial volumes

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  • Site-wide: 63,299
  • In neuroscience: 9,116
• Year to date:
  • Site-wide: 143,977
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  • Site-wide: 154,494

Improved prediction of schizophrenia by leveraging genetic overlap with brain morphology

• Downloaded 535 times
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  • Site-wide: 67,605
  • In psychiatry and clinical psychology: 264
• Year to date:
  • Site-wide: 39,386
• Since beginning of last month:
  • Site-wide: 30,042

Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

• Downloaded 471 times
• Download rankings, all-time:
  • Site-wide: 77,994
  • In genetics: 3,308
• Year to date:
  • Site-wide: 105,937
• Since beginning of last month:
  • Site-wide: 74,388

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

• Downloaded 441 times
• Download rankings, all-time:
  • Site-wide: 83,782
  • In genetics: 3,517
• Year to date:
  • Site-wide: 164,559
• Since beginning of last month:
  • Site-wide: 163,959

Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank

• Downloaded 425 times
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  • Site-wide: 86,927
  • In genetic and genomic medicine: 431
• Year to date:
  • Site-wide: 49,200
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  • Site-wide: 74,544

Population-based body-brain mapping links brain morphology and body composition

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  • Site-wide: 101,588
  • In neuroscience: 15,161
• Year to date:
  • Site-wide: 107,414
• Since beginning of last month:
  • Site-wide: 79,633

Characterization of Age and Polarity at Onset in Bipolar Disorder

• Downloaded 343 times
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  • Site-wide: 105,420
  • In psychiatry and clinical psychology: 467
• Year to date:
  • Site-wide: 28,176
• Since beginning of last month:
  • Site-wide: 39,850

A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia

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  • Site-wide: 105,629
  • In neuroscience: 15,800
• Year to date:
  • Site-wide: 48,343
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  • Site-wide: 71,699

Genetic overlap between Alzheimer's disease and depression mapped onto the brain

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  • Site-wide: 115,685
  • In genetic and genomic medicine: 653
• Year to date:
  • Site-wide: 33,874
• Since beginning of last month:
  • Site-wide: 84,909

Genome-wide association analysis reveals extensive genetic overlap between mood instability and psychiatric disorders but divergent patterns of genetic effects

• Downloaded 143 times
• Download rankings, all-time:
  • Site-wide: 154,042
  • In psychiatry and clinical psychology: 947
• Year to date:
  • Site-wide: 83,517
• Since beginning of last month:
  • Site-wide: 99,611