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Author: Oleksandr Frei

  • ORCiD: http://orcid.org/0000-0002-6427-2625
  • Most recently observed institution: NORMENT, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo

Rankings

  • All-time downloads: 37,389 (rank: 7,171 (tie) )
  • Categories:
    • addiction medicine: 144 (rank: 869 (tie) )
    • genetic and genomic medicine: 2,676 (rank: 2,209 (tie) )
    • genetics: 10,090 (rank: 2,130 (tie) )
    • genomics: 8,778 (rank: 3,140 )
    • neuroscience: 7,826 (rank: 3,124 )
    • psychiatry and clinical psychology: 5,723 (rank: 151 )

Downloads per author, site-wide

Preprints

A global view of pleiotropy and genetic architecture in complex traits

genetics more details view paper
  • Downloaded 3,815 times
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    • Site-wide: 4,998
    • In genetics: 168
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    • Site-wide: 8,321

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
  • Downloaded 3,654 times
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    • Site-wide: 5,317
    • In psychiatry and clinical psychology: 20
  • Year to date:
    • Site-wide: 11,691
  • Since beginning of last month:
    • Site-wide: 16,792

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

genomics more details view paper
  • Downloaded 3,490 times
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    • Site-wide: 5,696
    • In genomics: 520
  • Year to date:
    • Site-wide: 51,955
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    • Site-wide: 43,534

Genetics of brain age suggest an overlap with common brain disorders

neuroscience more details view paper
  • Downloaded 3,114 times
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    • Site-wide: 6,745
    • In neuroscience: 558
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Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness

genomics more details view paper
  • Downloaded 2,516 times
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    • Site-wide: 9,170
    • In genomics: 865
  • Year to date:
    • Site-wide: 27,053
  • Since beginning of last month:
    • Site-wide: 34,307

Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes

genomics more details view paper
  • Downloaded 1,431 times
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    • Site-wide: 21,840
    • In genomics: 1,908
  • Year to date:
    • Site-wide: 80,333
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    • Site-wide: 53,210

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

genetics more details view paper
  • Downloaded 1,389 times
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    • Site-wide: 22,953
    • In genetics: 915
  • Year to date:
    • Site-wide: 122,662
  • Since beginning of last month:
    • Site-wide: 48,540

Phenotypically independent mental health symptom profiles are genetically related

psychiatry and clinical psychology more details view paper
  • Downloaded 1,182 times
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    • Site-wide: 29,583
    • In psychiatry and clinical psychology: 118
  • Year to date:
    • Site-wide: 40,081
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    • Site-wide: 86,946

A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease

genetics more details view paper
  • Downloaded 1,112 times
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    • Site-wide: 32,562
    • In genetics: 1,313
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The genetic architecture of human cortical folding

genomics more details view paper
  • Downloaded 897 times
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    • Site-wide: 45,171
    • In genomics: 3,339
  • Year to date:
    • Site-wide: 27,192
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    • Site-wide: 174,782

The genetic architecture of human brainstem structures and their involvement in common brain disorders

neuroscience more details view paper
  • Downloaded 864 times
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    • Site-wide: 47,928
    • In neuroscience: 6,181
  • Year to date:
    • Site-wide: 151,944
  • Since beginning of last month:
    • Site-wide: 140,412

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy and improves prediction

genetics more details view paper
  • Downloaded 825 times
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    • Site-wide: 51,452
    • In genetics: 2,373
  • Year to date:
    • Site-wide: 4,618
  • Since beginning of last month:
    • Site-wide: 17,100

Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

genetics more details view paper
  • Downloaded 820 times
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    • Site-wide: 51,860
    • In genetics: 2,060
  • Year to date:
    • Site-wide: 49,372
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    • Site-wide: 88,027

Making the MOSTest of imaging genetics

neuroscience more details view paper
  • Downloaded 801 times
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    • Site-wide: 53,654
    • In neuroscience: 7,009
  • Year to date:
    • Site-wide: 170,943
  • Since beginning of last month:
    • Site-wide: 198,598

Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes

genetics more details view paper
  • Downloaded 787 times
  • Download rankings, all-time:
    • Site-wide: 55,049
    • In genetics: 2,132
  • Year to date:
    • Site-wide: 182,709
  • Since beginning of last month:
    • Site-wide: 88,712

Genome-wide association analysis of the human thalamus identifies novel genomic loci and reveals genetic overlap with distinct cortical regions and ten brain disorders

genetic and genomic medicine more details view paper
  • Downloaded 772 times
  • Download rankings, all-time:
    • Site-wide: 56,658
    • In genetic and genomic medicine: 327
  • Year to date:
    • Site-wide: 113,795
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    • Site-wide: 183,331

FEMA: Fast and efficient mixed-effects algorithm for population-scale whole brain imaging data

neuroscience more details view paper
  • Downloaded 764 times
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    • Site-wide: 57,516
    • In neuroscience: 10,055
  • Year to date:
    • Site-wide: 7,291
  • Since beginning of last month:
    • Site-wide: 9,315

Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits

neuroscience more details view paper
  • Downloaded 749 times
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    • Site-wide: 59,123
    • In neuroscience: 7,933
  • Year to date:
    • Site-wide: 187,050
  • Since beginning of last month:
    • Site-wide: 122,949

Improved prediction of schizophrenia by leveraging genetic overlap with brain morphology

psychiatry and clinical psychology more details view paper
  • Downloaded 688 times
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    • Site-wide: 66,883
    • In psychiatry and clinical psychology: 302
  • Year to date:
    • Site-wide: 72,853
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Genetic overlap between multivariate measures of human functional brain connectivity and psychiatric disorders

genetic and genomic medicine more details view paper
  • Downloaded 644 times
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    • Site-wide: 73,287
    • In genetic and genomic medicine: 461
  • Year to date:
    • Site-wide: 33,318
  • Since beginning of last month:
    • Site-wide: 61,428

Multivariate genome-wide association study on tissue-sensitive diffusion metrics identifies key molecular pathways for axonal growth, synaptogenesis, and astrocyte-mediated neuroinflammation

genetics more details view paper
  • Downloaded 626 times
  • Download rankings, all-time:
    • Site-wide: 76,099
    • In genetics: 2,961
  • Year to date:
    • Site-wide: 27,854
  • Since beginning of last month:
    • Site-wide: 98,533

Genetic control of variability in subcortical and intracranial volumes

neuroscience more details view paper
  • Downloaded 600 times
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    • Site-wide: 80,256
    • In neuroscience: 10,955
  • Year to date:
    • Site-wide: 199,726
  • Since beginning of last month:
    • Site-wide: 169,578

Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

genetics more details view paper
  • Downloaded 549 times
  • Download rankings, all-time:
    • Site-wide: 89,566
    • In genetics: 3,464
  • Year to date:
    • Site-wide: 119,096
  • Since beginning of last month:
    • Site-wide: 85,921

Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank

genetic and genomic medicine more details view paper
  • Downloaded 491 times
  • Download rankings, all-time:
    • Site-wide: 101,996
    • In genetic and genomic medicine: 617
  • Year to date:
    • Site-wide: 137,310
  • Since beginning of last month:
    • Site-wide: 163,284

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

genetics more details view paper
  • Downloaded 481 times
  • Download rankings, all-time:
    • Site-wide: 104,375
    • In genetics: 3,869
  • Year to date:
    • Site-wide: 195,637
  • Since beginning of last month:
    • Site-wide: 196,835

Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

neuroscience more details view paper
  • Downloaded 438 times
  • Download rankings, all-time:
    • Site-wide: 114,646
    • In neuroscience: 16,241
  • Year to date:
    • Site-wide: 204,129
  • Since beginning of last month:
    • Site-wide: 182,709

The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1

genetics more details view paper
  • Downloaded 409 times
  • Download rankings, all-time:
    • Site-wide: 122,108
    • In genetics: 6,457
  • Year to date:
    • Site-wide: 14,895
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    • Site-wide: 6,084

Population-based body-brain mapping links brain morphology and body composition

neuroscience more details view paper
  • Downloaded 401 times
  • Download rankings, all-time:
    • Site-wide: 124,436
    • In neuroscience: 17,310
  • Year to date:
    • Site-wide: 197,720
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Genome-wide association analysis reveals extensive genetic overlap between mood instability and psychiatric disorders but divergent patterns of genetic effects

psychiatry and clinical psychology more details view paper
  • Downloaded 400 times
  • Download rankings, all-time:
    • Site-wide: 124,761
    • In psychiatry and clinical psychology: 741
  • Year to date:
    • Site-wide: 36,737
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Genetic overlap between Alzheimer's disease and depression mapped onto the brain

genetic and genomic medicine more details view paper
  • Downloaded 365 times
  • Download rankings, all-time:
    • Site-wide: 134,822
    • In genetic and genomic medicine: 893
  • Year to date:
    • Site-wide: 149,145
  • Since beginning of last month:
    • Site-wide: 115,901

The role of liver fat in cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition

genomics more details view paper
  • Downloaded 350 times
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    • Site-wide: 139,332
    • In genomics: 7,713
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    • Site-wide: 19,159
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    • Site-wide: 29,248

Generalization of Cortical MOSTest Genome-Wide Associations Within and Across Samples

genomics more details view paper
  • Downloaded 343 times
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    • Site-wide: 141,332
    • In genomics: 7,489
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Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: UK Biobank 18608 example

neuroscience more details view paper
  • Downloaded 293 times
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    • Site-wide: 156,159
    • In neuroscience: 22,406
  • Year to date:
    • Site-wide: 197,100
  • Since beginning of last month:
    • Site-wide: 144,044

Distributed genetic architecture across the hippocampal formation implies common neuropathology across major brain disorders

genetic and genomic medicine more details view paper
  • Downloaded 269 times
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    • Site-wide: 163,329
    • In genetic and genomic medicine: 1,113
  • Year to date:
    • Site-wide: 95,443
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    • Site-wide: 204,486

The Genetic Architecture of Amygdala Nuclei

genetic and genomic medicine more details view paper
  • Downloaded 233 times
  • Download rankings, all-time:
    • Site-wide: 173,273
    • In genetic and genomic medicine: 1,263
  • Year to date:
    • Site-wide: 90,654
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    • Site-wide: 49,447

Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings

addiction medicine more details view paper
  • Downloaded 188 times
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    • Site-wide: 184,283
    • In addiction medicine: 119
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    • Site-wide: 48,507
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    • Site-wide: 39,958

Quantifying bone marrow adiposity and its genetic architecture from head MRI scans

genetic and genomic medicine more details view paper
  • Downloaded 143 times
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    • Site-wide: 193,504
    • In genetic and genomic medicine: None
  • Year to date:
    • Site-wide: 67,058
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    • Site-wide: 59,574

Efficient meta-analysis of multivariate genome-wide association studies with Meta-MOSTest

bioinformatics more details view paper
  • Downloaded 115 times
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    • Site-wide: 198,277
    • In bioinformatics: None
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Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness

neuroscience more details view paper
  • Downloaded 110 times
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    • Site-wide: 199,120
    • In neuroscience: 28,168
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    • Site-wide: 85,880
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    • Site-wide: 95,735

Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank

genetic and genomic medicine more details view paper
  • Downloaded 97 times
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    • Site-wide: 201,142
    • In genetic and genomic medicine: 1,536
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Polygenic architecture of a novel MRI endophenotype: the ''Hemochromatosis Brain''

neurology more details view paper
  • Downloaded 77 times
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    • Site-wide: 204,213
    • In neurology: None
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Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression.

genetic and genomic medicine more details view paper
  • Downloaded 67 times
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    • Site-wide: 205,633
    • In genetic and genomic medicine: None
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    • Site-wide: 30,727

Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

genetics more details view paper
  • Downloaded 30 times
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    • Site-wide: 209,264
    • In genetics: None
  • Year to date:
    • Site-wide: 204,589
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