Author: Srdjan Djurovic

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Preprints

Common risk variants identified in autism spectrum disorder

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  • Site-wide: 1,503
  • In genetics: 31
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  • Site-wide: 10,221
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  • Site-wide: 20,323

The genetic architecture of the human cerebral cortex

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  • Site-wide: 1,682
  • In genetics: 35
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  • Site-wide: 12,157
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  • Site-wide: 26,283

Genomewide association study identifies 30 loci associated with bipolar disorder

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  • Site-wide: 1,924
  • In genetics: 45
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  • Site-wide: 10,228
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  • Site-wide: 26,424

New insights on the genetic etiology of Alzheimer and related dementia

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  • Site-wide: 1,999
  • In neurology: 6
• Year to date:
  • Site-wide: 7,510
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  • Site-wide: 7,360

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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  • Site-wide: 2,830
  • In genetics: 79
• Year to date:
  • Site-wide: 7,015
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  • Site-wide: 30,041

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

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  • Site-wide: 3,097
  • In genetics: 86
• Year to date:
  • Site-wide: 56,904
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  • Site-wide: 61,564

Largest GWAS (N=1,126,563) of Alzheimer's Disease Implicates Microglia and Immune Cells

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  • Site-wide: 5,093
  • In genetic and genomic medicine: 26
• Year to date:
  • Site-wide: 5,640
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  • Site-wide: 17,486

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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  • Site-wide: 5,354
  • In psychiatry and clinical psychology: 20
• Year to date:
  • Site-wide: 12,402
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  • Site-wide: 19,304

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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  • Site-wide: 5,702
  • In genetics: 185
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  • Site-wide: 19,282
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  • Site-wide: 51,689

Genetics of brain age suggest an overlap with common brain disorders

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  • Site-wide: 6,817
  • In neuroscience: 586
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  • Site-wide: None
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  • Site-wide: 26,347

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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  • Site-wide: 7,455
  • In genetics: 275
• Year to date:
  • Site-wide: 10,332
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  • Site-wide: 8,933

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 13,690
  • In genetics: 525
• Year to date:
  • Site-wide: 57,513
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  • Site-wide: 201,316

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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  • Site-wide: 14,358
  • In genetics: 565
• Year to date:
  • Site-wide: 37,554
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  • Site-wide: 197,932

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 18,595
  • In genomics: 1,676
• Year to date:
  • Site-wide: 135,139
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  • Site-wide: 52,391

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

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  • Site-wide: 23,707
  • In genetics: 946
• Year to date:
  • Site-wide: 138,634
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  • Site-wide: 207,902

Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through cAMP/PKA pathway

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  • Site-wide: 29,088
  • In neuroscience: 3,556
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  • Site-wide: 67,675
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  • Site-wide: 35,413

Genome-wide association study identifies new locus associated with OCD

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  • Site-wide: 34,690
  • In psychiatry and clinical psychology: 149
• Year to date:
  • Site-wide: 17,210
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  • Site-wide: 11,217

Planar cell polarity pathway and development of the human visual cortex

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  • Site-wide: 39,347
  • In neuroscience: 5,184
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  • Site-wide: None
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  • Site-wide: 93,434

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 979 times
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  • Site-wide: 41,327
  • In genetics: 1,628
• Year to date:
  • Site-wide: 166,146
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  • Site-wide: 202,031

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

• Downloaded 938 times
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  • Site-wide: 44,141
  • In genetic and genomic medicine: 273
• Year to date:
  • Site-wide: 95,097
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  • Site-wide: 110,154

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy and improves prediction

• Downloaded 877 times
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  • Site-wide: 48,999
  • In genetics: 1,971
• Year to date:
  • Site-wide: 14,077
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  • Site-wide: 20,923

The genetic architecture of human brainstem structures and their involvement in common brain disorders

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  • Site-wide: 49,189
  • In neuroscience: 6,496
• Year to date:
  • Site-wide: 178,169
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  • Site-wide: 126,875

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

• Downloaded 858 times
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  • Site-wide: 50,597
  • In genetics: 1,961
• Year to date:
  • Site-wide: 135,862
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  • Site-wide: 180,165

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

• Downloaded 803 times
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  • Site-wide: 55,898
  • In genomics: 3,953
• Year to date:
  • Site-wide: 197,002
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  • Site-wide: 178,171

Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes

• Downloaded 794 times
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  • Site-wide: 56,828
  • In genetics: 2,190
• Year to date:
  • Site-wide: 174,335
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  • Site-wide: 151,819

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

• Downloaded 786 times
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  • Site-wide: 57,698
  • In genomics: 4,097
• Year to date:
  • Site-wide: 55,241
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  • Site-wide: 64,706

Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer Disease

• Downloaded 752 times
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  • Site-wide: 61,620
  • In psychiatry and clinical psychology: 276
• Year to date:
  • Site-wide: 131,190
• Since beginning of last month:
  • Site-wide: 98,667

Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers

• Downloaded 747 times
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  • Site-wide: 62,272
  • In neurology: 231
• Year to date:
  • Site-wide: 15,711
• Since beginning of last month:
  • Site-wide: 41,108

Improved prediction of schizophrenia by leveraging genetic overlap with brain morphology

• Downloaded 700 times
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  • Site-wide: 68,309
  • In psychiatry and clinical psychology: 312
• Year to date:
  • Site-wide: 94,522
• Since beginning of last month:
  • Site-wide: 158,454

All-optical electrophysiology in hiPSC-derived neurons with synthetic voltage sensors

• Downloaded 669 times
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  • Site-wide: 72,669
  • In neuroscience: 10,068
• Year to date:
  • Site-wide: 198,903
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  • Site-wide: 170,353

The dark side of the mean: brain structural heterogeneity in schizophrenia and its polygenic risk.

• Downloaded 644 times
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  • Site-wide: 76,611
  • In neuroscience: 10,928
• Year to date:
  • Site-wide: 100,582
• Since beginning of last month:
  • Site-wide: 116,845

Cardiometabolic risk factors associated with brain age and accelerate brain ageing

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  • Site-wide: 79,418
  • In neurology: 315
• Year to date:
  • Site-wide: 120,446
• Since beginning of last month:
  • Site-wide: 135,804

Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer disease: meta-analysis of 11 cohort studies

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  • Site-wide: 81,017
  • In genomics: 5,214
• Year to date:
  • Site-wide: 196,161
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  • Site-wide: 148,749

Genetic control of variability in subcortical and intracranial volumes

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  • Site-wide: 82,342
  • In neuroscience: 11,658
• Year to date:
  • Site-wide: 166,491
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  • Site-wide: 143,952

Characterization of Age and Polarity at Onset in Bipolar Disorder

• Downloaded 587 times
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  • Site-wide: 86,231
  • In psychiatry and clinical psychology: 418
• Year to date:
  • Site-wide: 151,356
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  • Site-wide: 58,246

Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

• Downloaded 561 times
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  • Site-wide: 91,344
  • In genetics: 3,511
• Year to date:
  • Site-wide: 76,833
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  • Site-wide: 188,759

Multimodal monitoring of human cortical organoids implanted in mice using transparent graphene microelectrodes reveal functional connection between organoid and mouse visual cortex

• Downloaded 504 times
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  • Site-wide: 103,677
  • In neuroscience: 17,863
• Year to date:
  • Site-wide: 10,676
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  • Site-wide: 7,709

Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank

• Downloaded 496 times
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  • Site-wide: 105,365
  • In genetic and genomic medicine: 680
• Year to date:
  • Site-wide: 181,274
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  • Site-wide: 187,690

Genome-wide association analysis reveals extensive genetic overlap between mood instability and psychiatric disorders but divergent patterns of genetic effects

• Downloaded 425 times
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  • Site-wide: 123,238
  • In psychiatry and clinical psychology: 704
• Year to date:
  • Site-wide: 85,654
• Since beginning of last month:
  • Site-wide: 28,577

A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia

• Downloaded 395 times
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  • Site-wide: 131,941
  • In neuroscience: 19,292
• Year to date:
  • Site-wide: 128,028
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  • Site-wide: 213,952

Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation

• Downloaded 292 times
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  • Site-wide: 162,851
  • In psychiatry and clinical psychology: 1,001
• Year to date:
  • Site-wide: 199,492
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  • Site-wide: 136,770

Cannabis use is associated with increased levels of soluble gp130 in schizophrenia but not in bipolar disorder

• Downloaded 261 times
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  • Site-wide: 171,953
  • In pharmacology and toxicology: 1,394
• Year to date:
  • Site-wide: 139,420
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  • Site-wide: 188,072

Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings

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  • Site-wide: 184,810
  • In addiction medicine: 132
• Year to date:
  • Site-wide: 84,277
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  • Site-wide: 63,649

Quantifying bone marrow adiposity and its genetic architecture from head MRI scans

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  • Site-wide: 195,040
  • In genetic and genomic medicine: 1,501
• Year to date:
  • Site-wide: 124,950
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  • Site-wide: 45,059

Identification of a sex-specific genetic signature in dementia with Lewy bodies: a meta-analysis of genome-wide association studies

• Downloaded 165 times
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  • Site-wide: 195,511
  • In genetic and genomic medicine: 1,547
• Year to date:
  • Site-wide: 18,773
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  • Site-wide: 12,950

Clustering schizophrenia genes by their temporal expression patterns aids functional interpretation: genetics-based evidence in favor of the two-hit hypothesis

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  • Site-wide: 198,489
  • In psychiatry and clinical psychology: 1,385
• Year to date:
  • Site-wide: 159,175
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  • Site-wide: 84,442

Inflammation and cognition in severe mental illness: Patterns of covariation and subgroups

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  • Site-wide: 209,921
  • In psychiatry and clinical psychology: 1,533
• Year to date:
  • Site-wide: 95,688
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  • Site-wide: 51,374

Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression.

• Downloaded 85 times
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  • Site-wide: 210,603
  • In genetic and genomic medicine: 1,700
• Year to date:
  • Site-wide: 70,565
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  • Site-wide: 74,201

Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study

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  • Site-wide: 213,474
  • In genetics: None
• Year to date:
  • Site-wide: 16,149
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  • Site-wide: 7,069