Author: Lu Lu

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Preprints

Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications

• Downloaded 127,670 times
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  • Site-wide: 30
  • In infectious diseases: 13
• Year to date:
  • Site-wide: 154
• Since beginning of last month:
  • Site-wide: 181

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

• Downloaded 15,762 times
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  • Site-wide: 443
  • In microbiology: 49
• Year to date:
  • Site-wide: 17,065
• Since beginning of last month:
  • Site-wide: 24,240

Antibody-dependent enhancement (ADE) of SARS-CoV-2 infection in recovered COVID-19 patients: studies based on cellular and structural biology analysis

• Downloaded 6,486 times
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  • Site-wide: 1,429
  • In infectious diseases: 378
• Year to date:
  • Site-wide: 444
• Since beginning of last month:
  • Site-wide: 579

Inhibition of SARS-CoV-2 infection (previously 2019-nCoV) by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

• Downloaded 5,927 times
• Download rankings, all-time:
  • Site-wide: 1,626
  • In microbiology: 137
• Year to date:
  • Site-wide: 17,280
• Since beginning of last month:
  • Site-wide: 28,137

Fully human single-domain antibodies against SARS-CoV-2

• Downloaded 4,898 times
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  • Site-wide: 2,113
  • In microbiology: 168
• Year to date:
  • Site-wide: 16,164
• Since beginning of last month:
  • Site-wide: 18,731

Monitoring SARS-CoV-2 circulation and diversity through community wastewater sequencing

• Downloaded 1,750 times
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  • Site-wide: 9,401
  • In public and global health: 214
• Year to date:
  • Site-wide: 2,729
• Since beginning of last month:
  • Site-wide: 5,210

Segmentation and shielding of the most vulnerable members of the population as elements of an exit strategy from COVID-19 lockdown

• Downloaded 1,691 times
• Download rankings, all-time:
  • Site-wide: 9,906
  • In epidemiology: 725
• Year to date:
  • Site-wide: 8,700
• Since beginning of last month:
  • Site-wide: 12,018

Systems biology informed deep learning for inferring parameters and hidden dynamics

• Downloaded 1,456 times
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  • Site-wide: 12,317
  • In bioinformatics: 1,488
• Year to date:
  • Site-wide: 16,846
• Since beginning of last month:
  • Site-wide: 12,822

Multi-Omic Profiling of the Liver Across Diets and Age in a Diverse Mouse Population

• Downloaded 1,310 times
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  • Site-wide: 14,459
  • In systems biology: 280
• Year to date:
  • Site-wide: 4,267
• Since beginning of last month:
  • Site-wide: 5,157

Interactions between strains govern the eco-evolutionary dynamics of microbial communities

• Downloaded 1,264 times
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  • Site-wide: 15,271
  • In microbiology: 872
• Year to date:
  • Site-wide: 1,050
• Since beginning of last month:
  • Site-wide: 14,778

The expanded BXD family of mice: A cohort for experimental systems genetics and precision medicine

• Downloaded 949 times
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  • Site-wide: 23,267
  • In genomics: 2,246
• Year to date:
  • Site-wide: 19,896
• Since beginning of last month:
  • Site-wide: 21,838

Engineered Trimeric ACE2 Binds and Locks “Three-up” Spike Protein to Potently Inhibit SARS-CoVs and Mutants

• Downloaded 727 times
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  • Site-wide: 33,894
  • In bioengineering: 612
• Year to date:
  • Site-wide: 44,411
• Since beginning of last month:
  • Site-wide: 87,863

Gene-by-environmental modulation of longevity and weight gain in the murine BXD family

• Downloaded 689 times
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  • Site-wide: 36,402
  • In genetics: 1,721
• Year to date:
  • Site-wide: 32,018
• Since beginning of last month:
  • Site-wide: 24,068

Epidemic waves of COVID-19 in Scotland: a genomic perspective on the impact of the introduction and relaxation of lockdown on SARS-CoV-2

• Downloaded 609 times
• Download rankings, all-time:
  • Site-wide: 42,699
  • In epidemiology: 2,026
• Year to date:
  • Site-wide: 2,922
• Since beginning of last month:
  • Site-wide: 8,872

A wild-derived antimutator drives germline mutation spectrum differences in a genetically diverse murine family

• Downloaded 607 times
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  • Site-wide: 42,955
  • In genetics: 2,008
• Year to date:
  • Site-wide: 2,940
• Since beginning of last month:
  • Site-wide: 2,778

Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

• Downloaded 546 times
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  • Site-wide: 48,888
  • In microbiology: 3,071
• Year to date:
  • Site-wide: 17,291
• Since beginning of last month:
  • Site-wide: 34,759

Identification of a functional non-coding variant in the GABAA receptor α2 subunit of the C57BL/6J mouse reference genome: Major implications for neuroscience research

• Downloaded 497 times
• Download rankings, all-time:
  • Site-wide: 54,661
  • In genetics: 2,514
• Year to date:
  • Site-wide: 95,429
• Since beginning of last month:
  • Site-wide: 136,185

Evolutionary origins of epidemic potential among human RNA viruses

• Downloaded 478 times
• Download rankings, all-time:
  • Site-wide: 57,117
  • In evolutionary biology: 3,065
• Year to date:
  • Site-wide: 62,644
• Since beginning of last month:
  • Site-wide: 99,572

Public good exploitation in natural bacterioplankton communities

• Downloaded 437 times
• Download rankings, all-time:
  • Site-wide: 62,594
  • In microbiology: 4,116
• Year to date:
  • Site-wide: 14,648
• Since beginning of last month:
  • Site-wide: None

Computational approaches towards reducing contamination in single-cell RNA-seq data

• Downloaded 405 times
• Download rankings, all-time:
  • Site-wide: 67,663
  • In bioinformatics: 6,518
• Year to date:
  • Site-wide: 64,765
• Since beginning of last month:
  • Site-wide: 59,478

Small-scale soil microbial community heterogeneity linked to landforms on King George Island, maritime Antarctica

• Downloaded 389 times
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  • Site-wide: 70,356
  • In microbiology: 4,731
• Year to date:
  • Site-wide: 86,464
• Since beginning of last month:
  • Site-wide: 64,407

Two key events associated with a transposable element burst occurred during rice domestication

• Downloaded 354 times
• Download rankings, all-time:
  • Site-wide: 76,662
  • In genomics: 5,141
• Year to date:
  • Site-wide: 109,271
• Since beginning of last month:
  • Site-wide: 110,749

Genetic dissection of femoral and tibial microarchitecture

• Downloaded 280 times
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  • Site-wide: 91,632
  • In genetics: 4,103
• Year to date:
  • Site-wide: 129,148
• Since beginning of last month:
  • Site-wide: 118,474

Association of maternal hepatitis B virus infection with adverse pregnancy outcomes and prenatal screening result of second-trimester: a retrospective cohort study

• Downloaded 261 times
• Download rankings, all-time:
  • Site-wide: 95,815
  • In obstetrics and gynecology: 82
• Year to date:
  • Site-wide: 94,745
• Since beginning of last month:
  • Site-wide: 76,161

High-Resolution Maps of Mouse Reference Populations

• Downloaded 260 times
• Download rankings, all-time:
  • Site-wide: 96,183
  • In genetics: 4,271
• Year to date:
  • Site-wide: 122,470
• Since beginning of last month:
  • Site-wide: 135,317

Tripterygium glycosides as a potential treatment for CAR-T induced cytokine release syndrome: implication of monocyte depletion

• Downloaded 245 times
• Download rankings, all-time:
  • Site-wide: 99,281
  • In hematology: 70
• Year to date:
  • Site-wide: 17,971
• Since beginning of last month:
  • Site-wide: 16,639

Genome-wide discovery of hidden genes mediating known drug-disease association using KDDANet

• Downloaded 227 times
• Download rankings, all-time:
  • Site-wide: 103,594
  • In bioinformatics: 8,796
• Year to date:
  • Site-wide: 122,483
• Since beginning of last month:
  • Site-wide: None

Genomic diversity generated by a transposable element burst in a rice recombinant inbred population

• Downloaded 163 times
• Download rankings, all-time:
  • Site-wide: 117,961
  • In genetics: 5,045
• Year to date:
  • Site-wide: 130,037
• Since beginning of last month:
  • Site-wide: 129,952

Apoptotic Extracellular Vesicles (ApoEVs) Safeguard Liver Homeostasis and Regeneration via Assembling an ApoEV-Golgi Organelle

• Downloaded 160 times
• Download rankings, all-time:
  • Site-wide: 118,470
  • In cell biology: 5,478
• Year to date:
  • Site-wide: 19,085
• Since beginning of last month:
  • Site-wide: 27,882

Plant endophytic bacteria: a potential resource pool of electroactive microorganisms

• Downloaded 101 times
• Download rankings, all-time:
  • Site-wide: 130,236
  • In microbiology: 9,977
• Year to date:
  • Site-wide: 68,117
• Since beginning of last month:
  • Site-wide: 129,766