Author: Lu Lu

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Preprints

Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications

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  • Site-wide: 32
  • In infectious diseases: 14
• Year to date:
  • Site-wide: 147
• Since beginning of last month:
  • Site-wide: 147

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

• Downloaded 15,691 times
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  • Site-wide: 413
  • In microbiology: 47
• Year to date:
  • Site-wide: 10,037
• Since beginning of last month:
  • Site-wide: 10,037

Inhibition of SARS-CoV-2 infection (previously 2019-nCoV) by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

• Downloaded 5,842 times
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  • Site-wide: 1,495
  • In microbiology: 125
• Year to date:
  • Site-wide: 12,338
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  • Site-wide: 12,338

Antibody-dependent enhancement (ADE) of SARS-CoV-2 infection in recovered COVID-19 patients: studies based on cellular and structural biology analysis

• Downloaded 5,363 times
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  • Site-wide: 1,681
  • In infectious diseases: 404
• Year to date:
  • Site-wide: 338
• Since beginning of last month:
  • Site-wide: 338

Fully human single-domain antibodies against SARS-CoV-2

• Downloaded 4,717 times
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  • Site-wide: 2,008
  • In microbiology: 152
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: None

Segmentation and shielding of the most vulnerable members of the population as elements of an exit strategy from COVID-19 lockdown

• Downloaded 1,515 times
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  • Site-wide: 10,522
  • In epidemiology: 743
• Year to date:
  • Site-wide: 9,185
• Since beginning of last month:
  • Site-wide: 9,185

Monitoring SARS-CoV-2 circulation and diversity through community wastewater sequencing

• Downloaded 1,487 times
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  • Site-wide: 10,787
  • In public and global health: 222
• Year to date:
  • Site-wide: 1,695
• Since beginning of last month:
  • Site-wide: 1,695

Systems biology informed deep learning for inferring parameters and hidden dynamics

• Downloaded 1,357 times
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  • Site-wide: 12,368
  • In bioinformatics: 1,530
• Year to date:
  • Site-wide: 14,591
• Since beginning of last month:
  • Site-wide: 14,591

Interactions between strains govern the eco-evolutionary dynamics of microbial communities

• Downloaded 1,033 times
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  • Site-wide: 18,699
  • In microbiology: 1,037
• Year to date:
  • Site-wide: 450
• Since beginning of last month:
  • Site-wide: 450

The Molecular Landscape of the Aging Mouse Liver

• Downloaded 906 times
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  • Site-wide: 22,515
  • In systems biology: 481
• Year to date:
  • Site-wide: 17,890
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  • Site-wide: 17,890

The expanded BXD family of mice: A cohort for experimental systems genetics and precision medicine

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  • Site-wide: 24,618
  • In genomics: 2,375
• Year to date:
  • Site-wide: 20,061
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  • Site-wide: 20,061

Engineered Trimeric ACE2 Binds and Locks “Three-up” Spike Protein to Potently Inhibit SARS-CoVs and Mutants

• Downloaded 713 times
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  • Site-wide: 31,581
  • In bioengineering: 557
• Year to date:
  • Site-wide: 19,713
• Since beginning of last month:
  • Site-wide: 19,713

Gene-by-environmental modulation of longevity and weight gain in the murine BXD family

• Downloaded 622 times
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  • Site-wide: 37,864
  • In genetics: 1,851
• Year to date:
  • Site-wide: 33,113
• Since beginning of last month:
  • Site-wide: 33,113

Identification of a functional non-coding variant in the GABAA receptor α2 subunit of the C57BL/6J mouse reference genome: Major implications for neuroscience research

• Downloaded 492 times
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  • Site-wide: 50,341
  • In genetics: 2,407
• Year to date:
  • Site-wide: 53,252
• Since beginning of last month:
  • Site-wide: 53,252

Evolutionary origins of epidemic potential among human RNA viruses

• Downloaded 450 times
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  • Site-wide: 55,618
  • In evolutionary biology: 3,094
• Year to date:
  • Site-wide: 53,624
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  • Site-wide: 53,624

Epidemic waves of COVID-19 in Scotland: a genomic perspective on the impact of the introduction and relaxation of lockdown on SARS-CoV-2

• Downloaded 442 times
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  • Site-wide: 56,598
  • In epidemiology: 2,411
• Year to date:
  • Site-wide: 1,365
• Since beginning of last month:
  • Site-wide: 1,365

Computational approaches towards reducing contamination in single-cell RNA-seq data

• Downloaded 382 times
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  • Site-wide: 65,438
  • In bioinformatics: 6,387
• Year to date:
  • Site-wide: 48,808
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  • Site-wide: 48,808

Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

• Downloaded 374 times
• Download rankings, all-time:
  • Site-wide: 66,899
  • In microbiology: 4,528
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: None

Small-scale soil microbial community heterogeneity linked to landforms on King George Island, maritime Antarctica

• Downloaded 368 times
• Download rankings, all-time:
  • Site-wide: 67,815
  • In microbiology: 4,600
• Year to date:
  • Site-wide: 90,598
• Since beginning of last month:
  • Site-wide: 90,598

Two key events associated with a transposable element burst occurred during rice domestication

• Downloaded 339 times
• Download rankings, all-time:
  • Site-wide: 72,705
  • In genomics: 4,994
• Year to date:
  • Site-wide: 111,845
• Since beginning of last month:
  • Site-wide: 111,845

Public good exploitation in natural bacterioplankton communities

• Downloaded 317 times
• Download rankings, all-time:
  • Site-wide: 76,742
  • In microbiology: 5,335
• Year to date:
  • Site-wide: 14,612
• Since beginning of last month:
  • Site-wide: 14,612

Genetic dissection of femoral and tibial microarchitecture

• Downloaded 272 times
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  • Site-wide: 85,871
  • In genetics: 3,948
• Year to date:
  • Site-wide: 115,544
• Since beginning of last month:
  • Site-wide: 115,544

High-Resolution Maps of Mouse Reference Populations

• Downloaded 255 times
• Download rankings, all-time:
  • Site-wide: 89,534
  • In genetics: 4,101
• Year to date:
  • Site-wide: 88,590
• Since beginning of last month:
  • Site-wide: 88,590

Association of maternal hepatitis B virus infection with adverse pregnancy outcomes and prenatal screening result of second-trimester: a retrospective cohort study

• Downloaded 244 times
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  • Site-wide: 91,872
  • In obstetrics and gynecology: 61
• Year to date:
  • Site-wide: 91,437
• Since beginning of last month:
  • Site-wide: 91,437

Genome-wide discovery of hidden genes mediating known drug-disease association

• Downloaded 218 times
• Download rankings, all-time:
  • Site-wide: 97,535
  • In bioinformatics: 8,430
• Year to date:
  • Site-wide: 109,810
• Since beginning of last month:
  • Site-wide: 109,810

Genomic diversity generated by a transposable element burst in a rice recombinant inbred population

• Downloaded 160 times
• Download rankings, all-time:
  • Site-wide: 109,558
  • In genetics: 4,850
• Year to date:
  • Site-wide: 93,603
• Since beginning of last month:
  • Site-wide: 93,603

Tripterygium glycosides as a potential treatment for CAR-T induced cytokine release syndrome: implication of monocyte depletion

• Downloaded 154 times
• Download rankings, all-time:
  • Site-wide: 110,911
  • In hematology: 69
• Year to date:
  • Site-wide: 14,457
• Since beginning of last month:
  • Site-wide: 14,457

Plant endophytic bacteria: a potential resource pool of electroactive microorganisms

• Downloaded 72 times
• Download rankings, all-time:
  • Site-wide: 124,838
  • In microbiology: 9,697
• Year to date:
  • Site-wide: 73,218
• Since beginning of last month:
  • Site-wide: 73,218