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Author: Nicholas T. Seyfried

Rankings

  • All-time downloads: 18,982 (rank: 12,009 )
  • Categories:
    • biochemistry: 1,878 (rank: 2,829 (tie) )
    • cell biology: 298 (rank: 33,952 (tie) )
    • genetics: 1,258 (rank: 14,575 (tie) )
    • genomics: 2,538 (rank: 10,556 (tie) )
    • neurology: 819 (rank: 1,868 (tie) )
    • neuroscience: 7,181 (rank: 2,635 )
    • systems biology: 5,010 (rank: 754 (tie) )

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Preprints

A Consensus Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

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Integrated Proteomics Reveals Brain-Based Cerebrospinal Fluid Biomarkers in Asymptomatic and Symptomatic Alzheimer’s Disease

systems biology more details view paper
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Multiscale causal network models of Alzheimer's disease identify VGF as a key regulator of disease

genomics more details view paper
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Genetic control of the human brain proteome

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Microglial ERK signaling is a critical regulator of pro-inflammatory immune responses in Alzheimer’s disease

neuroscience more details view paper
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    • In neuroscience: 3,402
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RNA-binding proteins with mixed charge domains self-assemble and aggregate in Alzheimer's Disease

biochemistry more details view paper
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Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer's Disease

neuroscience more details view paper
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Large-Scale Deep Multi-Layer Analysis of Alzheimer's Disease Brain Reveals Strong Proteomic Disease-Related Changes Not Observed at the RNA Level

systems biology more details view paper
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Identification of conserved proteomic networks in neurodegenerative dementia

neuroscience more details view paper
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Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior

neuroscience more details view paper
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    • Site-wide: 138,319

TBK1 interacts with tau and enhances neurodegeneration in tauopathy

neuroscience more details view paper
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Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease

neuroscience more details view paper
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Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease

neuroscience more details view paper
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    • In neuroscience: 8,147
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Integrated analysis of the aging brain transcriptome and proteome in tauopathy

genomics more details view paper
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    • In genomics: 4,328
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Middle-down proteomics reveals dense sites of methylation and phosphorylation in arginine-rich RNA-binding proteins

biochemistry more details view paper
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    • Site-wide: 68,150
    • In biochemistry: 1,828
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Large-scale proteomic analysis of human prefrontal cortex identifies proteins associated with cognitive trajectory in advanced age

neuroscience more details view paper
  • Downloaded 474 times
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    • Site-wide: 71,411
    • In neuroscience: 10,424
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Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus that are Necessary for Synapse Function

neuroscience more details view paper
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    • Site-wide: 73,721
    • In neuroscience: 10,779
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Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calmodulin (CaM) Effector in Mouse Brain

biochemistry more details view paper
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Cerebral atherosclerosis contributes to Alzheimer's dementia independently of its hallmark amyloid and tau pathologies

neuroscience more details view paper
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    • In neuroscience: 12,658
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Broad kinase inhibition mitigates early neuronal dysfunction and cognitive deficits in tauopathy

neuroscience more details view paper
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    • In neuroscience: 13,751
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Failure of the choroid plexus in Alzheimer's disease

neurology more details view paper
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    • Site-wide: 93,649
    • In neurology: 298
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Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

genomics more details view paper
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    • In genomics: 6,311
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Mitochondrial energy dysfunction induces remodeling of the cardiac mitochondrial protein acylome

cell biology more details view paper
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    • In cell biology: 5,030
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A Phase II Study Repurposing Atomoxetine for Neuroprotection in Mild Cognitive Impairment

neurology more details view paper
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    • In neurology: 519
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Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase and ethanolamides metabolism with Alzheimer's disease

neurology more details view paper
  • Downloaded 229 times
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    • In neurology: 527
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Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome.

neuroscience more details view paper
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    • In neuroscience: 19,271
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Cell type-specific biotin labeling in vivo resolves regional neuronal proteomic differences in mouse brain

neuroscience more details view paper
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