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Author: Yonatan M Grad

Rankings

  • All-time downloads: 173,946 (rank: 642 )
  • Categories:
    • bioinformatics: 5,961 (rank: 2,358 )
    • epidemiology: 121,872 (rank: 128 )
    • evolutionary biology: 2,104 (rank: 3,154 )
    • genomics: 8,274 (rank: 2,986 )
    • immunology: 665 (rank: 19,431 (tie) )
    • infectious diseases: 27,938 (rank: 2,408 )
    • microbiology: 6,111 (rank: 2,822 (tie) )
    • pharmacology and therapeutics: 1,021 (rank: 368 (tie) )

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Preprints

Prescribing of antibiotics and other drugs to children from birth to age 5 in the United States: an observational study

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Social distancing strategies for curbing the COVID-19 epidemic

epidemiology more details view paper
  • Downloaded 63,749 times
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    • Site-wide: 114
    • In epidemiology: 24
  • Year to date:
    • Site-wide: 1,583
  • Since beginning of last month:
    • Site-wide: 3,325

Projecting the transmission dynamics of SARS-CoV-2 through the post-pandemic period

epidemiology more details view paper
  • Downloaded 39,732 times
  • Download rankings, all-time:
    • Site-wide: 202
    • In epidemiology: 44
  • Year to date:
    • Site-wide: 5,539
  • Since beginning of last month:
    • Site-wide: 14,293

Model-informed COVID-19 vaccine prioritization strategies by age and serostatus

infectious diseases more details view paper
  • Downloaded 11,543 times
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    • Site-wide: 905
    • In infectious diseases: 293
  • Year to date:
    • Site-wide: 594
  • Since beginning of last month:
    • Site-wide: 5,177

Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated individuals

epidemiology more details view paper
  • Downloaded 8,852 times
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    • Site-wide: 1,247
    • In epidemiology: 161
  • Year to date:
    • Site-wide: 344
  • Since beginning of last month:
    • Site-wide: 110

Modeling the Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19

infectious diseases more details view paper
  • Downloaded 7,904 times
  • Download rankings, all-time:
    • Site-wide: 1,454
    • In infectious diseases: 425
  • Year to date:
    • Site-wide: 12,899
  • Since beginning of last month:
    • Site-wide: 24,819

Antimicrobial exposure in sexual networks drives divergent evolution in modern gonococci

genomics more details view paper
  • Downloaded 6,340 times
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    • Site-wide: 1,930
    • In genomics: 152
  • Year to date:
    • Site-wide: 84,053
  • Since beginning of last month:
    • Site-wide: 70,642

Rapid heuristic inference of antibiotic resistance and susceptibility by genomic neighbor typing

bioinformatics more details view paper
  • Downloaded 5,574 times
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    • Site-wide: 2,289
    • In bioinformatics: 165
  • Year to date:
    • Site-wide: 79,052
  • Since beginning of last month:
    • Site-wide: 120,809

Estimating SARS-CoV-2 seroprevalence and epidemiological parameters with uncertainty from serological surveys

infectious diseases more details view paper
  • Downloaded 4,152 times
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    • Site-wide: 3,448
    • In infectious diseases: 758
  • Year to date:
    • Site-wide: 20,243
  • Since beginning of last month:
    • Site-wide: 45,542

Building an International Consortium for Tracking Coronavirus Health Status

infectious diseases more details view paper
  • Downloaded 1,395 times
  • Download rankings, all-time:
    • Site-wide: 17,247
    • In infectious diseases: 1,906
  • Year to date:
    • Site-wide: 64,062
  • Since beginning of last month:
    • Site-wide: 47,656

Potential biases arising from epidemic dynamics in observational seroprotection studies

infectious diseases more details view paper
  • Downloaded 1,313 times
  • Download rankings, all-time:
    • Site-wide: 18,899
    • In infectious diseases: 2,004
  • Year to date:
    • Site-wide: 71,763
  • Since beginning of last month:
    • Site-wide: 128,672

Identification of hidden population structure in time-scaled phylogenies

evolutionary biology more details view paper
  • Downloaded 1,293 times
  • Download rankings, all-time:
    • Site-wide: 19,306
    • In evolutionary biology: 672
  • Year to date:
    • Site-wide: 83,207
  • Since beginning of last month:
    • Site-wide: 108,355

Vaccine waning and mumps re-emergence in the United States

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  • Downloaded 1,246 times
  • Download rankings, all-time:
    • Site-wide: 20,411
    • In epidemiology: 1,295
  • Year to date:
    • Site-wide: 130,848
  • Since beginning of last month:
    • Site-wide: 153,389

Containing Emerging Epidemics: a Quantitative Comparison of Quarantine and Symptom Monitoring

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  • Downloaded 1,200 times
  • Download rankings, all-time:
    • Site-wide: 21,629
    • In epidemiology: 1,349
  • Year to date:
    • Site-wide: 129,697
  • Since beginning of last month:
    • Site-wide: 136,924

Estimating the proportion of bystander selection for antibiotic resistance among potentially pathogenic bacterial flora

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  • Downloaded 1,124 times
  • Download rankings, all-time:
    • Site-wide: 23,898
    • In epidemiology: 1,440
  • Year to date:
    • Site-wide: 129,694
  • Since beginning of last month:
    • Site-wide: 118,321

Optimal design for phase 2 studies of SARS-CoV-2 antiviral drugs

pharmacology and therapeutics more details view paper
  • Downloaded 1,021 times
  • Download rankings, all-time:
    • Site-wide: 27,655
    • In pharmacology and therapeutics: 42
  • Year to date:
    • Site-wide: 5,171
  • Since beginning of last month:
    • Site-wide: 15,353

Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment

microbiology more details view paper
  • Downloaded 1,020 times
  • Download rankings, all-time:
    • Site-wide: 27,695
    • In microbiology: 1,609
  • Year to date:
    • Site-wide: 62,178
  • Since beginning of last month:
    • Site-wide: 126,331

The role of "spillover" in antibiotic resistance

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  • Downloaded 862 times
  • Download rankings, all-time:
    • Site-wide: 35,380
    • In epidemiology: 1,867
  • Year to date:
    • Site-wide: 35,129
  • Since beginning of last month:
    • Site-wide: 70,259

Co-circulating mumps lineages at multiple geographic scales

genomics more details view paper
  • Downloaded 850 times
  • Download rankings, all-time:
    • Site-wide: 36,077
    • In genomics: 2,978
  • Year to date:
    • Site-wide: 131,556
  • Since beginning of last month:
    • Site-wide: 135,132

Increasing Antibiotic Susceptibility In Staphylococcus aureus In Boston, Massachusetts, 2000-2014: An Observational Study

epidemiology more details view paper
  • Downloaded 818 times
  • Download rankings, all-time:
    • Site-wide: 38,205
    • In epidemiology: 1,984
  • Year to date:
    • Site-wide: 142,062
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    • Site-wide: 133,377

Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

evolutionary biology more details view paper
  • Downloaded 811 times
  • Download rankings, all-time:
    • Site-wide: 38,666
    • In evolutionary biology: 1,717
  • Year to date:
    • Site-wide: 157,698
  • Since beginning of last month:
    • Site-wide: 160,213

RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates

microbiology more details view paper
  • Downloaded 692 times
  • Download rankings, all-time:
    • Site-wide: 48,447
    • In microbiology: 2,925
  • Year to date:
    • Site-wide: 107,482
  • Since beginning of last month:
    • Site-wide: 87,764

Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data

microbiology more details view paper
  • Downloaded 678 times
  • Download rankings, all-time:
    • Site-wide: 49,741
    • In microbiology: 3,025
  • Year to date:
    • Site-wide: 152,565
  • Since beginning of last month:
    • Site-wide: 163,030

Jointly modeling prevalence, sensitivity and specificity for optimal sample allocation

immunology more details view paper
  • Downloaded 665 times
  • Download rankings, all-time:
    • Site-wide: 51,078
    • In immunology: 1,598
  • Year to date:
    • Site-wide: 40,463
  • Since beginning of last month:
    • Site-wide: 82,885

Comparative Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus despite strain-dependent differences in essentiality of shared cell envelope genes

microbiology more details view paper
  • Downloaded 657 times
  • Download rankings, all-time:
    • Site-wide: 51,953
    • In microbiology: 3,166
  • Year to date:
    • Site-wide: 109,943
  • Since beginning of last month:
    • Site-wide: 139,499

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch

genomics more details view paper
  • Downloaded 643 times
  • Download rankings, all-time:
    • Site-wide: 53,524
    • In genomics: 4,006
  • Year to date:
    • Site-wide: 36,958
  • Since beginning of last month:
    • Site-wide: 63,971

Impact of rapid susceptibility testing and antibiotic selection strategy on the emergence and spread of antibiotic resistance in gonorrhea

epidemiology more details view paper
  • Downloaded 597 times
  • Download rankings, all-time:
    • Site-wide: 58,948
    • In epidemiology: 2,726
  • Year to date:
    • Site-wide: 163,222
  • Since beginning of last month:
    • Site-wide: 164,210

Modeling the impact of racial and ethnic disparities on COVID-19 epidemic dynamics

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  • Downloaded 560 times
  • Download rankings, all-time:
    • Site-wide: 63,781
    • In epidemiology: 2,899
  • Year to date:
    • Site-wide: 13,318
  • Since beginning of last month:
    • Site-wide: 44,153

The distribution of antibiotic use and its association with antibiotic resistance

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  • Downloaded 540 times
  • Download rankings, all-time:
    • Site-wide: 66,658
    • In epidemiology: 2,999
  • Year to date:
    • Site-wide: 126,015
  • Since beginning of last month:
    • Site-wide: 63,262

Despite egg-adaptive mutations, the 2012-13 H3N2 influenza vaccine induced comparable antibody titers to the intended strain

epidemiology more details view paper
  • Downloaded 536 times
  • Download rankings, all-time:
    • Site-wide: 67,320
    • In epidemiology: 3,018
  • Year to date:
    • Site-wide: 149,539
  • Since beginning of last month:
    • Site-wide: 121,220

Increased power from bacterial genome-wide association conditional on known effects identifies Neisseria gonorrhoeae macrolide resistance mutations in the 50S ribosomal protein L4

microbiology more details view paper
  • Downloaded 528 times
  • Download rankings, all-time:
    • Site-wide: 68,547
    • In microbiology: 4,401
  • Year to date:
    • Site-wide: 113,218
  • Since beginning of last month:
    • Site-wide: 147,620

Azithromycin resistance through interspecific acquisition of an epistasis dependent efflux pump component and transcriptional regulator in Neisseria gonorrhoeae

microbiology more details view paper
  • Downloaded 517 times
  • Download rankings, all-time:
    • Site-wide: 70,171
    • In microbiology: 4,534
  • Year to date:
    • Site-wide: 157,718
  • Since beginning of last month:
    • Site-wide: 162,524

Dissecting the mechanisms of a 5-year decline in antibiotic prescribing

epidemiology more details view paper
  • Downloaded 495 times
  • Download rankings, all-time:
    • Site-wide: 73,864
    • In epidemiology: 3,268
  • Year to date:
    • Site-wide: 97,812
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    • Site-wide: 70,837

Trends in outpatient antibiotic prescribing practice among US older adults, 2011-2015: an observational study

epidemiology more details view paper
  • Downloaded 493 times
  • Download rankings, all-time:
    • Site-wide: 74,159
    • In epidemiology: 3,277
  • Year to date:
    • Site-wide: 149,511
  • Since beginning of last month:
    • Site-wide: 148,102

Photo-inactivation of Neisseria gonorrhoeae: A paradigm changing approach for combating antibiotic-resistant gonococcal infection

microbiology more details view paper
  • Downloaded 459 times
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    • Site-wide: 80,139
    • In microbiology: 5,311
  • Year to date:
    • Site-wide: 136,993
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    • Site-wide: 162,577

Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants

genomics more details view paper
  • Downloaded 441 times
  • Download rankings, all-time:
    • Site-wide: 83,769
    • In genomics: 5,426
  • Year to date:
    • Site-wide: 124,875
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    • Site-wide: 50,623

Potential impact of outpatient stewardship interventions on antibiotic exposures of bacterial pathogens

infectious diseases more details view paper
  • Downloaded 431 times
  • Download rankings, all-time:
    • Site-wide: 85,581
    • In infectious diseases: 4,301
  • Year to date:
    • Site-wide: 69,760
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    • Site-wide: 40,824

A Bayesian model of acquisition and clearance of bacterial colonization incorporating within-host variation

bioinformatics more details view paper
  • Downloaded 387 times
  • Download rankings, all-time:
    • Site-wide: 94,977
    • In bioinformatics: 8,261
  • Year to date:
    • Site-wide: 153,525
  • Since beginning of last month:
    • Site-wide: 117,178

Impact of population structure in the design of RNA-based diagnostics for antibiotic resistance in Neisseria gonorrhoeae

microbiology more details view paper
  • Downloaded 387 times
  • Download rankings, all-time:
    • Site-wide: 95,024
    • In microbiology: 6,510
  • Year to date:
    • Site-wide: 127,938
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    • Site-wide: 106,251

Genomic assessment of within-host population variation in Neisseria gonorrhoeae: Implications for gonorrhoea transmission

infectious diseases more details view paper
  • Downloaded 383 times
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    • Site-wide: 95,908
    • In infectious diseases: 4,572
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    • Site-wide: 48,601
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    • Site-wide: 76,494

High-frequency phase-switching of modB methylase is associated with phenotypic ceftriaxone susceptibility in Neisseria gonorrhoeae

microbiology more details view paper
  • Downloaded 358 times
  • Download rankings, all-time:
    • Site-wide: 101,727
    • In microbiology: 7,049
  • Year to date:
    • Site-wide: 98,222
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    • Site-wide: 82,741

Quantifying the surveillance required to sustain genetic marker-based antibiotic resistance diagnostics

microbiology more details view paper
  • Downloaded 353 times
  • Download rankings, all-time:
    • Site-wide: 103,026
    • In microbiology: 7,149
  • Year to date:
    • Site-wide: 152,377
  • Since beginning of last month:
    • Site-wide: 131,435

The distribution and spread of susceptible and resistant Neisseria gonorrhoeae across demographic groups in a major metropolitan center

infectious diseases more details view paper
  • Downloaded 316 times
  • Download rankings, all-time:
    • Site-wide: 112,182
    • In infectious diseases: 5,011
  • Year to date:
    • Site-wide: 100,049
  • Since beginning of last month:
    • Site-wide: 126,299

Reduction in antibiotic prescribing attainable with a gonococcal vaccine

epidemiology more details view paper
  • Downloaded 262 times
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    • Site-wide: 126,382
    • In epidemiology: 5,333
  • Year to date:
    • Site-wide: 77,419
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    • Site-wide: 72,193

Modeling MRSA decolonization: Interactions between body sites and the impact of site-specific clearance

infectious diseases more details view paper
  • Downloaded 259 times
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    • Site-wide: 127,157
    • In infectious diseases: 5,450
  • Year to date:
    • Site-wide: 49,423
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    • Site-wide: 73,176

The roles of stewardship and socioeconomic status in geographic variation in antibiotic prescribing: an observational study

epidemiology more details view paper
  • Downloaded 254 times
  • Download rankings, all-time:
    • Site-wide: 128,400
    • In epidemiology: 5,398
  • Year to date:
    • Site-wide: 94,956
  • Since beginning of last month:
    • Site-wide: 83,103

Large variation in the association between seasonal antibiotic use and resistance across multiple bacterial species and antibiotic classes

infectious diseases more details view paper
  • Downloaded 242 times
  • Download rankings, all-time:
    • Site-wide: 131,621
    • In infectious diseases: 5,561
  • Year to date:
    • Site-wide: 64,225
  • Since beginning of last month:
    • Site-wide: 56,681

Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae

microbiology more details view paper
  • Downloaded 221 times
  • Download rankings, all-time:
    • Site-wide: 136,838
    • In microbiology: 10,099
  • Year to date:
    • Site-wide: 88,001
  • Since beginning of last month:
    • Site-wide: 76,012

Test negative designs with uncertainty, sensitivity, and specificity

epidemiology more details view paper
  • Downloaded 219 times
  • Download rankings, all-time:
    • Site-wide: 137,414
    • In epidemiology: 5,731
  • Year to date:
    • Site-wide: 51,773
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    • Site-wide: 43,298

Efflux pump antibiotic binding site mutations are associated with azithromycin nonsusceptibility in clinical Neisseria gonorrhoeae isolates

microbiology more details view paper
  • Downloaded 173 times
  • Download rankings, all-time:
    • Site-wide: 148,135
    • In microbiology: 11,137
  • Year to date:
    • Site-wide: 160,426
  • Since beginning of last month:
    • Site-wide: 155,168

Trends in SARS-CoV-2 seroprevalence in Massachusetts estimated from newborn screening specimens

epidemiology more details view paper
  • Downloaded 170 times
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    • Site-wide: 148,832
    • In epidemiology: 6,178
  • Year to date:
    • Site-wide: 69,985
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    • Site-wide: 6,733

The anticipated artificial increase in life expectancy from COVID-19

epidemiology more details view paper
  • Downloaded 163 times
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    • Site-wide: 150,321
    • In epidemiology: 6,221
  • Year to date:
    • Site-wide: 72,853
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    • Site-wide: 123,722

Genome wide association studies define minimal set of loci for prediction of penicillin and tetracycline susceptibility in Neisseria gonorrhoeae

microbiology more details view paper
  • Downloaded 68 times
  • Download rankings, all-time:
    • Site-wide: 162,805
    • In microbiology: 12,554
  • Year to date:
    • Site-wide: 142,473
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    • Site-wide: 130,680

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