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Author: Xin Chen

Rankings

  • All-time downloads: 71,425 (rank: 3,163 )
  • Categories:
    • biochemistry: 981 (rank: 7,854 (tie) )
    • bioinformatics: 3,906 (rank: 4,244 (tie) )
    • biophysics: 2,084 (rank: 3,001 (tie) )
    • cancer biology: 2,556 (rank: 3,100 (tie) )
    • dentistry and oral medicine: 334 (rank: 478 (tie) )
    • developmental biology: 4,747 (rank: 561 )
    • ecology: 706 (rank: 8,422 (tie) )
    • emergency medicine: 3,021 (rank: 66 (tie) )
    • epidemiology: 391 (rank: 26,095 (tie) )
    • evolutionary biology: 602 (rank: 15,041 (tie) )
    • genetics: 841 (rank: 21,394 (tie) )
    • genomics: 4,300 (rank: 6,954 )
    • immunology: 3,500 (rank: 4,142 (tie) )
    • infectious diseases: 1,673 (rank: 24,482 (tie) )
    • microbiology: 1,117 (rank: 18,208 (tie) )
    • molecular biology: 356 (rank: 23,972 (tie) )
    • neuroscience: 1,132 (rank: 28,819 (tie) )
    • ophthalmology: 1,152 (rank: 112 (tie) )
    • pathology: 1,250 (rank: 1,361 )
    • physiology: 1,263 (rank: 934 (tie) )
    • public and global health: 27,248 (rank: 294 )
    • radiology and imaging: 685 (rank: 975 (tie) )
    • scientific communication and education: 1,411 (rank: 707 (tie) )
    • synthetic biology: 1,160 (rank: 2,435 (tie) )
    • systems biology: 482 (rank: 11,113 (tie) )

Downloads per author, site-wide

Preprints

Rab7/Retromer-based endolysosomal trafficking facilitates effector secretion and host invasion in rice blast

plant biology more details view paper

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Yeast U6 snRNA made by RNA polymerase II is less stable but functional

molecular biology more details view paper

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Immunogenicity and Safety of a SARS-CoV-2 Inactivated Vaccine in Healthy Adults Aged 18-59 years: Report of the Randomized, Double-blind, and Placebo-controlled Phase 2 Clinical Trial

public and global health more details view paper
  • Downloaded 27,557 times
  • Download rankings, all-time:
    • Site-wide: 367
    • In public and global health: 17
  • Year to date:
    • Site-wide: 2,171
  • Since beginning of last month:
    • Site-wide: 4,185

Fate mapping via Ms4a3 expression history traces monocyte-derived cells

immunology more details view paper
  • Downloaded 3,562 times
  • Download rankings, all-time:
    • Site-wide: 5,076
    • In immunology: 182
  • Year to date:
    • Site-wide: 46,402
  • Since beginning of last month:
    • Site-wide: 47,183

A Novel Triage Tool of Artificial Intelligence Assisted Diagnosis Aid System for Suspected COVID-19 pneumonia In Fever Clinics

emergency medicine more details view paper
  • Downloaded 3,099 times
  • Download rankings, all-time:
    • Site-wide: 6,243
    • In emergency medicine: 8
  • Year to date:
    • Site-wide: 30,888
  • Since beginning of last month:
    • Site-wide: 49,305

Unidirectional fork movement coupled with strand-specific histone incorporation ensures asymmetric histone inheritance

developmental biology more details view paper
  • Downloaded 2,379 times
  • Download rankings, all-time:
    • Site-wide: 9,181
    • In developmental biology: 99
  • Year to date:
    • Site-wide: 115,347
  • Since beginning of last month:
    • Site-wide: 125,301

Personalized deep learning of individual immunopeptidomes to identify neoantigens for cancer vaccines

bioinformatics more details view paper
  • Downloaded 2,137 times
  • Download rankings, all-time:
    • Site-wide: 10,741
    • In bioinformatics: 1,164
  • Year to date:
    • Site-wide: 25,119
  • Since beginning of last month:
    • Site-wide: 33,459

Allocation of COVID-19 Vaccines Under Limited Supply

infectious diseases more details view paper
  • Downloaded 1,748 times
  • Download rankings, all-time:
    • Site-wide: 14,516
    • In infectious diseases: 1,870
  • Year to date:
    • Site-wide: 37,320
  • Since beginning of last month:
    • Site-wide: 50,214

A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples

genomics more details view paper
  • Downloaded 1,617 times
  • Download rankings, all-time:
    • Site-wide: 16,274
    • In genomics: 1,461
  • Year to date:
    • Site-wide: 94,859
  • Since beginning of last month:
    • Site-wide: 94,710

The Big Five, Self-efficacy, and Self-control in Boxers

scientific communication and education more details view paper
  • Downloaded 1,547 times
  • Download rankings, all-time:
    • Site-wide: 17,487
    • In scientific communication and education: 137
  • Year to date:
    • Site-wide: 25,143
  • Since beginning of last month:
    • Site-wide: 22,360

A Comprehensive Multi-Center Cross-platform Benchmarking Study of Single-cell RNA Sequencing Using Reference Samples

genomics more details view paper
  • Downloaded 1,462 times
  • Download rankings, all-time:
    • Site-wide: 19,032
    • In genomics: 1,699
  • Year to date:
    • Site-wide: 71,947
  • Since beginning of last month:
    • Site-wide: 70,731

ŌvSim: a Simulation of the Population Dynamics of Mammalian Ovarian Follicles

physiology more details view paper
  • Downloaded 1,278 times
  • Download rankings, all-time:
    • Site-wide: 23,485
    • In physiology: 62
  • Year to date:
    • Site-wide: 150,399
  • Since beginning of last month:
    • Site-wide: 138,943

Low-Bias Amplification for Robust DNA Data Readout

synthetic biology more details view paper
  • Downloaded 1,215 times
  • Download rankings, all-time:
    • Site-wide: 25,428
    • In synthetic biology: 314
  • Year to date:
    • Site-wide: 70,343
  • Since beginning of last month:
    • Site-wide: 59,374

A Pairwise Distance Distribution Correction (DDC) algorithm to eliminate blinking-caused artifacts in super-resolution microscopy

biophysics more details view paper
  • Downloaded 1,152 times
  • Download rankings, all-time:
    • Site-wide: 27,575
    • In biophysics: 736
  • Year to date:
    • Site-wide: 59,840
  • Since beginning of last month:
    • Site-wide: 78,295

Stem cell mitotic drive ensures asymmetric epigenetic inheritance

developmental biology more details view paper
  • Downloaded 1,137 times
  • Download rankings, all-time:
    • Site-wide: 28,167
    • In developmental biology: 477
  • Year to date:
    • Site-wide: 105,776
  • Since beginning of last month:
    • Site-wide: 113,336

Identifying strategies to target the metabolic flexibility of tumours

cancer biology more details view paper
  • Downloaded 1,126 times
  • Download rankings, all-time:
    • Site-wide: 28,527
    • In cancer biology: 669
  • Year to date:
    • Site-wide: 114,128
  • Since beginning of last month:
    • Site-wide: 82,181

Single-cell transcriptome analysis reveals estrogen signaling augments the mitochondrial folate pathway to coordinately fuel purine and polyamine synthesis in breast cancer cells

genomics more details view paper
  • Downloaded 1,124 times
  • Download rankings, all-time:
    • Site-wide: 28,620
    • In genomics: 2,346
  • Year to date:
    • Site-wide: 164,928
  • Since beginning of last month:
    • Site-wide: 112,125

Knowledge about benefits and risks of undergoing cataract surgery among cataract patients in Southern China

ophthalmology more details view paper
  • Downloaded 919 times
  • Download rankings, all-time:
    • Site-wide: 38,709
    • In ophthalmology: 16
  • Year to date:
    • Site-wide: 39,310
  • Since beginning of last month:
    • Site-wide: 31,095

Mapping and Inheritance analysis of a novel dominant rice male sterility mutant, OsDMS-1

genetics more details view paper
  • Downloaded 859 times
  • Download rankings, all-time:
    • Site-wide: 42,642
    • In genetics: 1,678
  • Year to date:
    • Site-wide: 143,931
  • Since beginning of last month:
    • Site-wide: 138,991

Robust retrieval of data stored in DNA by de Bruijn graph-based de novo strand assembly

bioinformatics more details view paper
  • Downloaded 839 times
  • Download rankings, all-time:
    • Site-wide: 44,282
    • In bioinformatics: 5,658
  • Year to date:
    • Site-wide: 17,411
  • Since beginning of last month:
    • Site-wide: 36,965

Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells

biophysics more details view paper
  • Downloaded 835 times
  • Download rankings, all-time:
    • Site-wide: 44,587
    • In biophysics: 1,408
  • Year to date:
    • Site-wide: 75,925
  • Since beginning of last month:
    • Site-wide: 57,592

GeneQC: A quality control tool for gene expression estimation based on RNA-sequencing reads mapping

bioinformatics more details view paper
  • Downloaded 817 times
  • Download rankings, all-time:
    • Site-wide: 45,934
    • In bioinformatics: 4,427
  • Year to date:
    • Site-wide: 139,121
  • Since beginning of last month:
    • Site-wide: 153,688

Instructive starPEG-Heparin biohybrid 3D cultures for modeling human neural stem cell plasticity, neurogenesis, and neurodegeneration

neuroscience more details view paper
  • Downloaded 708 times
  • Download rankings, all-time:
    • Site-wide: 56,434
    • In neuroscience: 7,663
  • Year to date:
    • Site-wide: 92,931
  • Since beginning of last month:
    • Site-wide: 62,436

Chest Computed Tomography for the Diagnosis of Patients with Coronavirus Disease 2019 (COVID-19): A Rapid Review and Meta-Analysis

radiology and imaging more details view paper
  • Downloaded 702 times
  • Download rankings, all-time:
    • Site-wide: 57,141
    • In radiology and imaging: 95
  • Year to date:
    • Site-wide: 107,627
  • Since beginning of last month:
    • Site-wide: 152,528

A human antibody with blocking activity to RBD proteins of multiple SARS-CoV-2 variants including B.1.351 showed potent prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus macaques

microbiology more details view paper
  • Downloaded 673 times
  • Download rankings, all-time:
    • Site-wide: 60,668
    • In microbiology: 4,299
  • Year to date:
    • Site-wide: 36,862
  • Since beginning of last month:
    • Site-wide: 12,648

Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning

pathology more details view paper
  • Downloaded 665 times
  • Download rankings, all-time:
    • Site-wide: 61,678
    • In pathology: 266
  • Year to date:
    • Site-wide: 157,044
  • Since beginning of last month:
    • Site-wide: 184,537

A novel long noncoding RNA LINC00844 regulates prostate cancer cell migration and invasion through androgen receptor signaling

cancer biology more details view paper
  • Downloaded 650 times
  • Download rankings, all-time:
    • Site-wide: 63,471
    • In cancer biology: 1,761
  • Year to date:
    • Site-wide: 90,878
  • Since beginning of last month:
    • Site-wide: 112,813

A tale of winglets: evolution of flight morphology in stick insects

evolutionary biology more details view paper
  • Downloaded 617 times
  • Download rankings, all-time:
    • Site-wide: 68,005
    • In evolutionary biology: 3,006
  • Year to date:
    • Site-wide: 147,414
  • Since beginning of last month:
    • Site-wide: 146,996

Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 602 times
  • Download rankings, all-time:
    • Site-wide: 70,283
    • In microbiology: 4,452
  • Year to date:
    • Site-wide: 71,128
  • Since beginning of last month:
    • Site-wide: 96,979

Asymmetric histone inheritance regulates stem cell fate in Drosophila midgut

developmental biology more details view paper
  • Downloaded 596 times
  • Download rankings, all-time:
    • Site-wide: 71,124
    • In developmental biology: 1,814
  • Year to date:
    • Site-wide: 66,677
  • Since beginning of last month:
    • Site-wide: 79,153

A Genetically Encoded Trimethylsilyl 1D 1H-NMR Probe for Conformation Change in Large Membrane Protein Complexes

biochemistry more details view paper
  • Downloaded 583 times
  • Download rankings, all-time:
    • Site-wide: 73,147
    • In biochemistry: 1,824
  • Year to date:
    • Site-wide: 157,189
  • Since beginning of last month:
    • Site-wide: 151,151

Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

biochemistry more details view paper
  • Downloaded 563 times
  • Download rankings, all-time:
    • Site-wide: 76,245
    • In biochemistry: None
  • Year to date:
    • Site-wide: 4,258
  • Since beginning of last month:
    • Site-wide: 566

Circular RNAs regulate cancer stem cells by FMRP against CCAR1 complex in hepatocellular carcinoma

cancer biology more details view paper
  • Downloaded 552 times
  • Download rankings, all-time:
    • Site-wide: 78,147
    • In cancer biology: 2,110
  • Year to date:
    • Site-wide: 166,209
  • Since beginning of last month:
    • Site-wide: 183,056

A probabilistic model-based bi-clustering method for single-cell transcriptomic data analysis

bioinformatics more details view paper
  • Downloaded 530 times
  • Download rankings, all-time:
    • Site-wide: 82,028
    • In bioinformatics: 7,006
  • Year to date:
    • Site-wide: 181,718
  • Since beginning of last month:
    • Site-wide: 168,536

Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8

biochemistry more details view paper
  • Downloaded 502 times
  • Download rankings, all-time:
    • Site-wide: 87,436
    • In biochemistry: 2,767
  • Year to date:
    • Site-wide: 45,161
  • Since beginning of last month:
    • Site-wide: 14,389

RECTA: Regulon Identification Based on Comparative Genomics and Transcriptomics Analysis

systems biology more details view paper
  • Downloaded 490 times
  • Download rankings, all-time:
    • Site-wide: 89,896
    • In systems biology: 1,805
  • Year to date:
    • Site-wide: 176,474
  • Since beginning of last month:
    • Site-wide: 172,799

Distinct pattern of autofluorescence of the skin and fingernails of acute ischemic stroke patients: A novel diagnostic biomarker for acute ischemic stroke

neuroscience more details view paper
  • Downloaded 476 times
  • Download rankings, all-time:
    • Site-wide: 92,865
    • In neuroscience: 12,730
  • Year to date:
    • Site-wide: 160,144
  • Since beginning of last month:
    • Site-wide: 143,222

Differential condensation of sister chromatids coordinates with Cdc6 to ensure distinct cell cycle progression in Drosophila male germline stem cell lineage

developmental biology more details view paper
  • Downloaded 428 times
  • Download rankings, all-time:
    • Site-wide: 103,904
    • In developmental biology: 2,958
  • Year to date:
    • Site-wide: 58,399
  • Since beginning of last month:
    • Site-wide: 32,975

Characterization of histone inheritance patterns in the Drosophila female germline

developmental biology more details view paper
  • Downloaded 408 times
  • Download rankings, all-time:
    • Site-wide: 108,581
    • In developmental biology: 2,739
  • Year to date:
    • Site-wide: 143,069
  • Since beginning of last month:
    • Site-wide: 131,404

Relationship between ecological stoichiometry and community diversity of plant ecosystems in the upper reaches of the Tarim River, China

ecology more details view paper
  • Downloaded 399 times
  • Download rankings, all-time:
    • Site-wide: 110,890
    • In ecology: 2,916
  • Year to date:
    • Site-wide: 145,189
  • Since beginning of last month:
    • Site-wide: 136,195

Green autofluorescence intensity of skin and fingernails: A novel biomarker for non-invasive evaluation of pathological state of blood vessels

pathology more details view paper
  • Downloaded 376 times
  • Download rankings, all-time:
    • Site-wide: 116,877
    • In pathology: 574
  • Year to date:
    • Site-wide: 170,262
  • Since beginning of last month:
    • Site-wide: 171,666

A Multi-center Cross-platform Single-cell RNA Sequencing Reference Dataset

bioinformatics more details view paper
  • Downloaded 372 times
  • Download rankings, all-time:
    • Site-wide: 117,940
    • In bioinformatics: 9,262
  • Year to date:
    • Site-wide: 156,661
  • Since beginning of last month:
    • Site-wide: 163,782

Mixed Culture of Bacterial Cell for Large Scale DNA Storage

molecular biology more details view paper
  • Downloaded 369 times
  • Download rankings, all-time:
    • Site-wide: 118,730
    • In molecular biology: 3,266
  • Year to date:
    • Site-wide: 173,035
  • Since beginning of last month:
    • Site-wide: 151,593

Prevalence, incidence and risk factors for myopia among urban and rural children in southern China: protocol for a school-based cohort study

ophthalmology more details view paper
  • Downloaded 368 times
  • Download rankings, all-time:
    • Site-wide: 119,153
    • In ophthalmology: 131
  • Year to date:
    • Site-wide: 75,705
  • Since beginning of last month:
    • Site-wide: 38,530

Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition

developmental biology more details view paper
  • Downloaded 357 times
  • Download rankings, all-time:
    • Site-wide: 122,277
    • In developmental biology: None
  • Year to date:
    • Site-wide: 8,488
  • Since beginning of last month:
    • Site-wide: 20,216

Associated habitat and suitability modeling of goldenseal (Hydrastis canadensis L.) in Pennsylvania: explaining and predicting species distribution in a northern edge of range state

ecology more details view paper
  • Downloaded 355 times
  • Download rankings, all-time:
    • Site-wide: 122,699
    • In ecology: 3,512
  • Year to date:
    • Site-wide: 105,904
  • Since beginning of last month:
    • Site-wide: 125,652

Trabeculae microstructure parameters serve as effective predictors for marginal bone loss of dental implant in the mandible

dentistry and oral medicine more details view paper
  • Downloaded 352 times
  • Download rankings, all-time:
    • Site-wide: 123,465
    • In dentistry and oral medicine: 87
  • Year to date:
    • Site-wide: 141,279
  • Since beginning of last month:
    • Site-wide: 130,457

Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development

cancer biology more details view paper
  • Downloaded 323 times
  • Download rankings, all-time:
    • Site-wide: 131,770
    • In cancer biology: 3,717
  • Year to date:
    • Site-wide: 179,403
  • Since beginning of last month:
    • Site-wide: 161,234

The Human walking kinematic model combined with upper and lower limb movement

biophysics more details view paper
  • Downloaded 264 times
  • Download rankings, all-time:
    • Site-wide: 149,447
    • In biophysics: 5,913
  • Year to date:
    • Site-wide: 65,027
  • Since beginning of last month:
    • Site-wide: 22,777

Sleep disturbances and related factors among preschool children in rural areas of China: a cross-sectional study

epidemiology more details view paper
  • Downloaded 262 times
  • Download rankings, all-time:
    • Site-wide: 149,894
    • In epidemiology: 6,108
  • Year to date:
    • Site-wide: 74,553
  • Since beginning of last month:
    • Site-wide: 56,571

RASSF1A independence and early Galectin-1 upregulation in PIK3CA induced hepatocarcinogenesis: new therapeutic venues

pathology more details view paper
  • Downloaded 253 times
  • Download rankings, all-time:
    • Site-wide: 152,563
    • In pathology: 843
  • Year to date:
    • Site-wide: 127,588
  • Since beginning of last month:
    • Site-wide: 104,962

Modulation of glucose metabolism by 2-Deoxy-D-Glucose (2DG) promotes IL-17 producing human T cell subsets

immunology more details view paper
  • Downloaded 249 times
  • Download rankings, all-time:
    • Site-wide: 153,915
    • In immunology: None
  • Year to date:
    • Site-wide: 14,605
  • Since beginning of last month:
    • Site-wide: 31,712

Algorithm optimization for weighted gene co-expression network analysis: accelerating the calculation of Topology Overlap Matrices with OpenMP and SQLite

bioinformatics more details view paper
  • Downloaded 247 times
  • Download rankings, all-time:
    • Site-wide: 154,206
    • In bioinformatics: 11,612
  • Year to date:
    • Site-wide: 96,592
  • Since beginning of last month:
    • Site-wide: 50,137

Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retina

genomics more details view paper
  • Downloaded 204 times
  • Download rankings, all-time:
    • Site-wide: 165,960
    • In genomics: 7,818
  • Year to date:
    • Site-wide: 178,624
  • Since beginning of last month:
    • Site-wide: 160,607

Trends and Patterns of Opioid Epidemic: A Large-Scale Retrospective Study of Hospital Visits with Opioid Poisoning in New York State, 2010-2016

public and global health more details view paper
  • Downloaded 188 times
  • Download rankings, all-time:
    • Site-wide: 170,131
    • In public and global health: 2,282
  • Year to date:
    • Site-wide: 179,485
  • Since beginning of last month:
    • Site-wide: 129,858

Does Obstructive sleep apnea increase the risk of Parkinson Disease? A systematic review and meta-analysis.

epidemiology more details view paper
  • Downloaded 180 times
  • Download rankings, all-time:
    • Site-wide: 171,977
    • In epidemiology: 6,687
  • Year to date:
    • Site-wide: 161,576
  • Since beginning of last month:
    • Site-wide: 117,833

Testing the link between isoaspartate and Alzheimer's disease etiology

neuroscience more details view paper
  • Downloaded 82 times
  • Download rankings, all-time:
    • Site-wide: 187,997
    • In neuroscience: None
  • Year to date:
    • Site-wide: 58,820
  • Since beginning of last month:
    • Site-wide: 13,149

Multifaceted role of RIMBP2 in promoting hearing in murine cochlear hair cells

neuroscience more details view paper
  • Downloaded 71 times
  • Download rankings, all-time:
    • Site-wide: 188,934
    • In neuroscience: None
  • Year to date:
    • Site-wide: 67,174
  • Since beginning of last month:
    • Site-wide: 16,827

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