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Author: Xin Chen

Rankings

  • All-time downloads: 76,706 (rank: 3,087 (tie) )
  • Categories:
    • biochemistry: 1,876 (rank: 3,906 (tie) )
    • bioinformatics: 5,273 (rank: 3,224 (tie) )
    • biophysics: 2,353 (rank: 3,001 (tie) )
    • cancer biology: 2,809 (rank: 3,363 )
    • cell biology: 105 (rank: 54,726 (tie) )
    • dentistry and oral medicine: 356 (rank: 492 (tie) )
    • developmental biology: 5,449 (rank: 510 )
    • ecology: 769 (rank: 8,903 (tie) )
    • emergency medicine: 3,128 (rank: 66 (tie) )
    • epidemiology: 461 (rank: 27,039 (tie) )
    • evolutionary biology: 620 (rank: 16,548 (tie) )
    • genetics: 868 (rank: 22,670 (tie) )
    • genomics: 4,447 (rank: 7,238 )
    • immunology: 3,982 (rank: 4,227 )
    • infectious diseases: 1,783 (rank: 25,769 (tie) )
    • microbiology: 1,451 (rank: 15,997 (tie) )
    • molecular biology: 486 (rank: 21,622 (tie) )
    • neuroscience: 1,409 (rank: 26,623 (tie) )
    • ophthalmology: 1,398 (rank: 102 (tie) )
    • pathology: 1,319 (rank: 1,398 )
    • physiology: 1,287 (rank: 1,206 (tie) )
    • plant biology: 153 (rank: 26,115 (tie) )
    • public and global health: 27,900 (rank: 295 )
    • radiology and imaging: 706 (rank: 1,130 (tie) )
    • scientific communication and education: 1,571 (rank: 697 (tie) )
    • synthetic biology: 1,242 (rank: 2,583 (tie) )
    • systems biology: 498 (rank: 12,005 (tie) )

Downloads per author, site-wide

Preprints

Immunogenicity and Safety of a SARS-CoV-2 Inactivated Vaccine in Healthy Adults Aged 18-59 years: Report of the Randomized, Double-blind, and Placebo-controlled Phase 2 Clinical Trial

public and global health more details view paper
  • Downloaded 27,907 times
  • Download rankings, all-time:
    • Site-wide: 382
    • In public and global health: 17
  • Year to date:
    • Site-wide: 2,493
  • Since beginning of last month:
    • Site-wide: 6,021

Fate mapping via Ms4a3 expression history traces monocyte-derived cells

immunology more details view paper
  • Downloaded 3,636 times
  • Download rankings, all-time:
    • Site-wide: 5,352
    • In immunology: 207
  • Year to date:
    • Site-wide: 53,183
  • Since beginning of last month:
    • Site-wide: 29,622

A Novel Triage Tool of Artificial Intelligence Assisted Diagnosis Aid System for Suspected COVID-19 pneumonia In Fever Clinics

emergency medicine more details view paper
  • Downloaded 3,189 times
  • Download rankings, all-time:
    • Site-wide: 6,527
    • In emergency medicine: 8
  • Year to date:
    • Site-wide: 35,905
  • Since beginning of last month:
    • Site-wide: 34,519

Unidirectional fork movement coupled with strand-specific histone incorporation ensures asymmetric histone inheritance

developmental biology more details view paper
  • Downloaded 2,422 times
  • Download rankings, all-time:
    • Site-wide: 9,743
    • In developmental biology: 104
  • Year to date:
    • Site-wide: 117,651
  • Since beginning of last month:
    • Site-wide: 54,919

Personalized deep learning of individual immunopeptidomes to identify neoantigens for cancer vaccines

bioinformatics more details view paper
  • Downloaded 2,250 times
  • Download rankings, all-time:
    • Site-wide: 10,900
    • In bioinformatics: 1,138
  • Year to date:
    • Site-wide: 27,114
  • Since beginning of last month:
    • Site-wide: 56,952

Allocation of COVID-19 Vaccines Under Limited Supply

infectious diseases more details view paper
  • Downloaded 1,871 times
  • Download rankings, all-time:
    • Site-wide: 14,397
    • In infectious diseases: 1,954
  • Year to date:
    • Site-wide: 33,080
  • Since beginning of last month:
    • Site-wide: 26,879

The Big Five, Self-efficacy, and Self-control in Boxers

scientific communication and education more details view paper
  • Downloaded 1,760 times
  • Download rankings, all-time:
    • Site-wide: 15,831
    • In scientific communication and education: 130
  • Year to date:
    • Site-wide: 16,822
  • Since beginning of last month:
    • Site-wide: 3,629

A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples

genomics more details view paper
  • Downloaded 1,688 times
  • Download rankings, all-time:
    • Site-wide: 16,847
    • In genomics: 1,549
  • Year to date:
    • Site-wide: 81,993
  • Since beginning of last month:
    • Site-wide: 109,959

A Comprehensive Multi-Center Cross-platform Benchmarking Study of Single-cell RNA Sequencing Using Reference Samples

genomics more details view paper
  • Downloaded 1,546 times
  • Download rankings, all-time:
    • Site-wide: 19,380
    • In genomics: 1,750
  • Year to date:
    • Site-wide: 64,483
  • Since beginning of last month:
    • Site-wide: 20,546

ŌvSim: a Simulation of the Population Dynamics of Mammalian Ovarian Follicles

physiology more details view paper
  • Downloaded 1,310 times
  • Download rankings, all-time:
    • Site-wide: 25,231
    • In physiology: 78
  • Year to date:
    • Site-wide: 155,403
  • Since beginning of last month:
    • Site-wide: 105,150

Low-Bias Amplification for Robust DNA Data Readout

synthetic biology more details view paper
  • Downloaded 1,276 times
  • Download rankings, all-time:
    • Site-wide: 26,308
    • In synthetic biology: 323
  • Year to date:
    • Site-wide: 74,716
  • Since beginning of last month:
    • Site-wide: 47,771

A Pairwise Distance Distribution Correction (DDC) algorithm to eliminate blinking-caused artifacts in super-resolution microscopy

biophysics more details view paper
  • Downloaded 1,212 times
  • Download rankings, all-time:
    • Site-wide: 28,500
    • In biophysics: 794
  • Year to date:
    • Site-wide: 68,677
  • Since beginning of last month:
    • Site-wide: 31,720

Identifying strategies to target the metabolic flexibility of tumours

cancer biology more details view paper
  • Downloaded 1,176 times
  • Download rankings, all-time:
    • Site-wide: 29,885
    • In cancer biology: 747
  • Year to date:
    • Site-wide: 108,353
  • Since beginning of last month:
    • Site-wide: 63,676

Stem cell mitotic drive ensures asymmetric epigenetic inheritance

developmental biology more details view paper
  • Downloaded 1,172 times
  • Download rankings, all-time:
    • Site-wide: 30,077
    • In developmental biology: 533
  • Year to date:
    • Site-wide: 121,843
  • Since beginning of last month:
    • Site-wide: 108,443

Single-cell transcriptome analysis reveals estrogen signaling augments the mitochondrial folate pathway to coordinately fuel purine and polyamine synthesis in breast cancer cells

genomics more details view paper
  • Downloaded 1,156 times
  • Download rankings, all-time:
    • Site-wide: 30,701
    • In genomics: 2,512
  • Year to date:
    • Site-wide: 165,270
  • Since beginning of last month:
    • Site-wide: 68,446

Knowledge about benefits and risks of undergoing cataract surgery among cataract patients in Southern China

ophthalmology more details view paper
  • Downloaded 1,027 times
  • Download rankings, all-time:
    • Site-wide: 36,848
    • In ophthalmology: 18
  • Year to date:
    • Site-wide: 37,367
  • Since beginning of last month:
    • Site-wide: 20,438

Robust retrieval of data stored in DNA by de Bruijn graph-based de novo strand assembly

bioinformatics more details view paper
  • Downloaded 940 times
  • Download rankings, all-time:
    • Site-wide: 42,238
    • In bioinformatics: 4,458
  • Year to date:
    • Site-wide: 22,203
  • Since beginning of last month:
    • Site-wide: 40,650

Mapping and Inheritance analysis of a novel dominant rice male sterility mutant, OsDMS-1

genetics more details view paper
  • Downloaded 891 times
  • Download rankings, all-time:
    • Site-wide: 45,760
    • In genetics: 1,785
  • Year to date:
    • Site-wide: 151,983
  • Since beginning of last month:
    • Site-wide: 126,443

Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells

biophysics more details view paper
  • Downloaded 870 times
  • Download rankings, all-time:
    • Site-wide: 47,531
    • In biophysics: 1,445
  • Year to date:
    • Site-wide: 97,519
  • Since beginning of last month:
    • Site-wide: 153,362

GeneQC: A quality control tool for gene expression estimation based on RNA-sequencing reads mapping

bioinformatics more details view paper
  • Downloaded 865 times
  • Download rankings, all-time:
    • Site-wide: 47,975
    • In bioinformatics: 4,854
  • Year to date:
    • Site-wide: 121,605
  • Since beginning of last month:
    • Site-wide: 46,431

A human antibody with blocking activity to RBD proteins of multiple SARS-CoV-2 variants including B.1.351 showed potent prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus macaques

microbiology more details view paper
  • Downloaded 837 times
  • Download rankings, all-time:
    • Site-wide: 50,419
    • In microbiology: 2,984
  • Year to date:
    • Site-wide: 26,152
  • Since beginning of last month:
    • Site-wide: None

Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

biochemistry more details view paper
  • Downloaded 807 times
  • Download rankings, all-time:
    • Site-wide: 53,257
    • In biochemistry: 1,582
  • Year to date:
    • Site-wide: 4,851
  • Since beginning of last month:
    • Site-wide: 12,899

Chest Computed Tomography for the Diagnosis of Patients with Coronavirus Disease 2019 (COVID-19): A Rapid Review and Meta-Analysis

radiology and imaging more details view paper
  • Downloaded 728 times
  • Download rankings, all-time:
    • Site-wide: 61,837
    • In radiology and imaging: 114
  • Year to date:
    • Site-wide: 137,364
  • Since beginning of last month:
    • Site-wide: 184,086

Instructive starPEG-Heparin biohybrid 3D cultures for modeling human neural stem cell plasticity, neurogenesis, and neurodegeneration

neuroscience more details view paper
  • Downloaded 726 times
  • Download rankings, all-time:
    • Site-wide: 62,099
    • In neuroscience: 8,270
  • Year to date:
    • Site-wide: 135,706
  • Since beginning of last month:
    • Site-wide: 193,324

A novel long noncoding RNA LINC00844 regulates prostate cancer cell migration and invasion through androgen receptor signaling

cancer biology more details view paper
  • Downloaded 699 times
  • Download rankings, all-time:
    • Site-wide: 65,530
    • In cancer biology: 1,882
  • Year to date:
    • Site-wide: 96,711
  • Since beginning of last month:
    • Site-wide: 68,381

Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 688 times
  • Download rankings, all-time:
    • Site-wide: 67,056
    • In microbiology: 4,098
  • Year to date:
    • Site-wide: 63,547
  • Since beginning of last month:
    • Site-wide: 74,967

Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning

pathology more details view paper
  • Downloaded 687 times
  • Download rankings, all-time:
    • Site-wide: 67,197
    • In pathology: 295
  • Year to date:
    • Site-wide: 183,985
  • Since beginning of last month:
    • Site-wide: 152,008

A tale of winglets: evolution of flight morphology in stick insects

evolutionary biology more details view paper
  • Downloaded 647 times
  • Download rankings, all-time:
    • Site-wide: 72,967
    • In evolutionary biology: 3,257
  • Year to date:
    • Site-wide: 157,428
  • Since beginning of last month:
    • Site-wide: 81,469

Asymmetric histone inheritance regulates stem cell fate in Drosophila midgut

developmental biology more details view paper
  • Downloaded 640 times
  • Download rankings, all-time:
    • Site-wide: 74,024
    • In developmental biology: 1,785
  • Year to date:
    • Site-wide: 82,871
  • Since beginning of last month:
    • Site-wide: 110,538

Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8

biochemistry more details view paper
  • Downloaded 616 times
  • Download rankings, all-time:
    • Site-wide: 77,774
    • In biochemistry: 2,115
  • Year to date:
    • Site-wide: 39,443
  • Since beginning of last month:
    • Site-wide: 86,294

A Genetically Encoded Trimethylsilyl 1D 1H-NMR Probe for Conformation Change in Large Membrane Protein Complexes

biochemistry more details view paper
  • Downloaded 613 times
  • Download rankings, all-time:
    • Site-wide: 78,228
    • In biochemistry: 2,027
  • Year to date:
    • Site-wide: 163,709
  • Since beginning of last month:
    • Site-wide: 197,918

Circular RNAs regulate cancer stem cells by FMRP against CCAR1 complex in hepatocellular carcinoma

cancer biology more details view paper
  • Downloaded 586 times
  • Download rankings, all-time:
    • Site-wide: 82,858
    • In cancer biology: 2,396
  • Year to date:
    • Site-wide: 160,744
  • Since beginning of last month:
    • Site-wide: 106,396

A probabilistic model-based bi-clustering method for single-cell transcriptomic data analysis

bioinformatics more details view paper
  • Downloaded 555 times
  • Download rankings, all-time:
    • Site-wide: 88,570
    • In bioinformatics: 7,743
  • Year to date:
    • Site-wide: 191,769
  • Since beginning of last month:
    • Site-wide: 123,490

Differential condensation of sister chromatids coordinates with Cdc6 to ensure distinct cell cycle progression in Drosophila male germline stem cell lineage

developmental biology more details view paper
  • Downloaded 543 times
  • Download rankings, all-time:
    • Site-wide: 91,008
    • In developmental biology: 2,285
  • Year to date:
    • Site-wide: 45,937
  • Since beginning of last month:
    • Site-wide: 136,568

RECTA: Regulon Identification Based on Comparative Genomics and Transcriptomics Analysis

systems biology more details view paper
  • Downloaded 526 times
  • Download rankings, all-time:
    • Site-wide: 94,527
    • In systems biology: 1,965
  • Year to date:
    • Site-wide: 161,733
  • Since beginning of last month:
    • Site-wide: 80,157

Algorithm optimization for weighted gene co-expression network analysis: accelerating the calculation of Topology Overlap Matrices with OpenMP and SQLite

bioinformatics more details view paper
  • Downloaded 508 times
  • Download rankings, all-time:
    • Site-wide: 98,372
    • In bioinformatics: 8,537
  • Year to date:
    • Site-wide: 24,107
  • Since beginning of last month:
    • Site-wide: None

Distinct 'pattern of autofluorescence' of acute ischemic stroke patients' skin and fingernails: A novel diagnostic biomarker for acute ischemic stroke

neuroscience more details view paper
  • Downloaded 498 times
  • Download rankings, all-time:
    • Site-wide: 100,554
    • In neuroscience: 13,943
  • Year to date:
    • Site-wide: 185,475
  • Since beginning of last month:
    • Site-wide: None

Prevalence, incidence and risk factors for myopia among urban and rural children in southern China: protocol for a school-based cohort study

ophthalmology more details view paper
  • Downloaded 472 times
  • Download rankings, all-time:
    • Site-wide: 106,720
    • In ophthalmology: 93
  • Year to date:
    • Site-wide: 57,816
  • Since beginning of last month:
    • Site-wide: 175,301

Relationship between ecological stoichiometry and community diversity of plant ecosystems in the upper reaches of the Tarim River, China

ecology more details view paper
  • Downloaded 447 times
  • Download rankings, all-time:
    • Site-wide: 112,547
    • In ecology: 3,174
  • Year to date:
    • Site-wide: 123,835
  • Since beginning of last month:
    • Site-wide: 51,368

Characterization of histone inheritance patterns in the Drosophila female germline

developmental biology more details view paper
  • Downloaded 429 times
  • Download rankings, all-time:
    • Site-wide: 117,219
    • In developmental biology: 2,990
  • Year to date:
    • Site-wide: 176,953
  • Since beginning of last month:
    • Site-wide: 196,188

Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition

developmental biology more details view paper
  • Downloaded 414 times
  • Download rankings, all-time:
    • Site-wide: 121,162
    • In developmental biology: 3,287
  • Year to date:
    • Site-wide: 14,790
  • Since beginning of last month:
    • Site-wide: 42,241

Mixed Culture of Bacterial Cell for Large Scale DNA Storage

molecular biology more details view paper
  • Downloaded 405 times
  • Download rankings, all-time:
    • Site-wide: 123,544
    • In molecular biology: 3,589
  • Year to date:
    • Site-wide: 159,924
  • Since beginning of last month:
    • Site-wide: 150,702

Green autofluorescence intensity of skin and fingernails: A novel biomarker for non-invasive evaluation of pathological state of blood vessels

pathology more details view paper
  • Downloaded 403 times
  • Download rankings, all-time:
    • Site-wide: 124,277
    • In pathology: 640
  • Year to date:
    • Site-wide: 180,791
  • Since beginning of last month:
    • Site-wide: 126,586

Associated habitat and suitability modeling of goldenseal (Hydrastis canadensis L.) in Pennsylvania: explaining and predicting species distribution in a northern edge of range state

ecology more details view paper
  • Downloaded 401 times
  • Download rankings, all-time:
    • Site-wide: 124,759
    • In ecology: 3,669
  • Year to date:
    • Site-wide: 108,553
  • Since beginning of last month:
    • Site-wide: 56,764

A Multi-center Cross-platform Single-cell RNA Sequencing Reference Dataset

bioinformatics more details view paper
  • Downloaded 397 times
  • Download rankings, all-time:
    • Site-wide: 125,770
    • In bioinformatics: 9,918
  • Year to date:
    • Site-wide: 177,160
  • Since beginning of last month:
    • Site-wide: 188,381

Trabeculae microstructure parameters serve as effective predictors for marginal bone loss of dental implant in the mandible

dentistry and oral medicine more details view paper
  • Downloaded 377 times
  • Download rankings, all-time:
    • Site-wide: 131,543
    • In dentistry and oral medicine: 90
  • Year to date:
    • Site-wide: 165,821
  • Since beginning of last month:
    • Site-wide: 155,203

Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development

cancer biology more details view paper
  • Downloaded 374 times
  • Download rankings, all-time:
    • Site-wide: 132,551
    • In cancer biology: 3,911
  • Year to date:
    • Site-wide: 135,196
  • Since beginning of last month:
    • Site-wide: 189,338

The Human walking kinematic model combined with upper and lower limb movement

biophysics more details view paper
  • Downloaded 371 times
  • Download rankings, all-time:
    • Site-wide: 133,294
    • In biophysics: 5,060
  • Year to date:
    • Site-wide: 51,634
  • Since beginning of last month:
    • Site-wide: 140,334

Modulation of glucose metabolism by 2-Deoxy-D-Glucose (2DG) promotes IL-17 producing human T cell subsets

immunology more details view paper
  • Downloaded 362 times
  • Download rankings, all-time:
    • Site-wide: 136,111
    • In immunology: 4,754
  • Year to date:
    • Site-wide: 18,450
  • Since beginning of last month:
    • Site-wide: 20,782

Engineering human Mucosal Associated Invariant T (MAIT) cells with chimeric antigen receptors for cancer immunotherapy

immunology more details view paper
  • Downloaded 326 times
  • Download rankings, all-time:
    • Site-wide: 146,896
    • In immunology: 6,002
  • Year to date:
    • Site-wide: 21,778
  • Since beginning of last month:
    • Site-wide: 8,182

Sleep disturbances and related factors among preschool children in rural areas of China: a cross-sectional study

epidemiology more details view paper
  • Downloaded 302 times
  • Download rankings, all-time:
    • Site-wide: 153,737
    • In epidemiology: 6,313
  • Year to date:
    • Site-wide: 92,418
  • Since beginning of last month:
    • Site-wide: 100,875

RASSF1A independence and early Galectin-1 upregulation in PIK3CA induced hepatocarcinogenesis: new therapeutic venues

pathology more details view paper
  • Downloaded 287 times
  • Download rankings, all-time:
    • Site-wide: 158,237
    • In pathology: 890
  • Year to date:
    • Site-wide: 138,876
  • Since beginning of last month:
    • Site-wide: 159,675

Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retina

genomics more details view paper
  • Downloaded 220 times
  • Download rankings, all-time:
    • Site-wide: 176,947
    • In genomics: 8,400
  • Year to date:
    • Site-wide: 205,201
  • Since beginning of last month:
    • Site-wide: 186,718

In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

cancer biology more details view paper
  • Downloaded 212 times
  • Download rankings, all-time:
    • Site-wide: 179,123
    • In cancer biology: 6,011
  • Year to date:
    • Site-wide: 41,560
  • Since beginning of last month:
    • Site-wide: 11,474

Trends and Patterns of Opioid Epidemic: A Large-Scale Retrospective Study of Hospital Visits with Opioid Poisoning in New York State, 2010-2016

public and global health more details view paper
  • Downloaded 210 times
  • Download rankings, all-time:
    • Site-wide: 179,630
    • In public and global health: 2,562
  • Year to date:
    • Site-wide: 196,166
  • Since beginning of last month:
    • Site-wide: 149,494

Does Obstructive sleep apnea increase the risk of Parkinson Disease? A systematic review and meta-analysis.

epidemiology more details view paper
  • Downloaded 207 times
  • Download rankings, all-time:
    • Site-wide: 180,299
    • In epidemiology: 7,163
  • Year to date:
    • Site-wide: 172,774
  • Since beginning of last month:
    • Site-wide: 176,626

Rab7/Retromer-based endolysosomal trafficking facilitates effector secretion and host invasion in rice blast

plant biology more details view paper
  • Downloaded 199 times
  • Download rankings, all-time:
    • Site-wide: 182,077
    • In plant biology: 5,131
  • Year to date:
    • Site-wide: 45,384
  • Since beginning of last month:
    • Site-wide: 37,734

Equalizing epigenetically imprinted centromeres in early mammalian embryos

developmental biology more details view paper
  • Downloaded 182 times
  • Download rankings, all-time:
    • Site-wide: 185,959
    • In developmental biology: None
  • Year to date:
    • Site-wide: 51,289
  • Since beginning of last month:
    • Site-wide: 2,232

Monoallelically-expressed Noncoding RNAs form nucleolar territories on NOR-containing chromosomes and regulate rRNA expression

cell biology more details view paper
  • Downloaded 166 times
  • Download rankings, all-time:
    • Site-wide: 189,448
    • In cell biology: 8,737
  • Year to date:
    • Site-wide: 57,596
  • Since beginning of last month:
    • Site-wide: 34,049

Testing the link between isoaspartate and Alzheimer's disease etiology

neuroscience more details view paper
  • Downloaded 165 times
  • Download rankings, all-time:
    • Site-wide: 189,663
    • In neuroscience: 27,343
  • Year to date:
    • Site-wide: 58,052
  • Since beginning of last month:
    • Site-wide: 129,306

Yeast U6 snRNA made by RNA polymerase II is less stable but functional

molecular biology more details view paper
  • Downloaded 123 times
  • Download rankings, all-time:
    • Site-wide: 197,301
    • In molecular biology: 5,753
  • Year to date:
    • Site-wide: 78,413
  • Since beginning of last month:
    • Site-wide: 129,850

Roles of the distinct N-terminal amino acid between H3 and H3.3 in Drosophila male germline stem cell lineage

developmental biology more details view paper
  • Downloaded 100 times
  • Download rankings, all-time:
    • Site-wide: 201,085
    • In developmental biology: None
  • Year to date:
    • Site-wide: 94,459
  • Since beginning of last month:
    • Site-wide: 41,839

Multifaceted role of RIMBP2 in promoting hearing in murine cochlear hair cells

neuroscience more details view paper
  • Downloaded 87 times
  • Download rankings, all-time:
    • Site-wide: 203,109
    • In neuroscience: 28,346
  • Year to date:
    • Site-wide: 106,853
  • Since beginning of last month:
    • Site-wide: 203,915

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