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Author: Xin Chen

  • ORCiD: http://orcid.org/0000-0002-6990-0926
  • Most recently observed institution: Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, 94117 San Francisco, California

Rankings

  • All-time downloads: 65,110 (rank: 2,914 )
  • Categories:
    • biochemistry: 948 (rank: 7,521 )
    • bioinformatics: 3,769 (rank: 4,220 (tie) )
    • biophysics: 2,015 (rank: 2,702 (tie) )
    • cancer biology: 2,514 (rank: 2,908 (tie) )
    • dentistry and oral medicine: 321 (rank: 457 (tie) )
    • developmental biology: 4,643 (rank: 462 )
    • ecology: 684 (rank: 8,067 (tie) )
    • emergency medicine: 2,921 (rank: 66 (tie) )
    • epidemiology: 337 (rank: 26,256 (tie) )
    • evolutionary biology: 591 (rank: 14,410 (tie) )
    • genetics: 831 (rank: 20,702 (tie) )
    • genomics: 4,236 (rank: 6,659 )
    • immunology: 3,451 (rank: 3,658 (tie) )
    • infectious diseases: 1,598 (rank: 22,551 (tie) )
    • microbiology: 1,062 (rank: 17,869 (tie) )
    • molecular biology: 350 (rank: 22,543 (tie) )
    • neuroscience: 1,101 (rank: 27,637 (tie) )
    • ophthalmology: 1,065 (rank: 122 (tie) )
    • pathology: 1,221 (rank: 1,259 )
    • physiology: 1,239 (rank: 810 (tie) )
    • public and global health: 26,599 (rank: 291 )
    • radiology and imaging: 654 (rank: 935 (tie) )
    • scientific communication and education: 1,369 (rank: 701 (tie) )
    • synthetic biology: 1,120 (rank: 2,349 (tie) )
    • systems biology: 471 (rank: 10,722 (tie) )

Downloads per author, site-wide

Preprints

Immunogenicity and Safety of a SARS-CoV-2 Inactivated Vaccine in Healthy Adults Aged 18-59 years: Report of the Randomized, Double-blind, and Placebo-controlled Phase 2 Clinical Trial

public and global health more details view paper
  • Downloaded 26,428 times
  • Download rankings, all-time:
    • Site-wide: 330
    • In public and global health: 16
  • Year to date:
    • Site-wide: 187
  • Since beginning of last month:
    • Site-wide: 586

Fate mapping via Ms4a3 expression history traces monocyte-derived cells

immunology more details view paper
  • Downloaded 3,451 times
  • Download rankings, all-time:
    • Site-wide: 4,488
    • In immunology: 159
  • Year to date:
    • Site-wide: 21,489
  • Since beginning of last month:
    • Site-wide: 47,516

A Novel Triage Tool of Artificial Intelligence Assisted Diagnosis Aid System for Suspected COVID-19 pneumonia In Fever Clinics

emergency medicine more details view paper
  • Downloaded 2,921 times
  • Download rankings, all-time:
    • Site-wide: 5,727
    • In emergency medicine: 8
  • Year to date:
    • Site-wide: 7,486
  • Since beginning of last month:
    • Site-wide: 7,290

Unidirectional fork movement coupled with strand-specific histone incorporation ensures asymmetric histone inheritance

developmental biology more details view paper
  • Downloaded 2,342 times
  • Download rankings, all-time:
    • Site-wide: 7,902
    • In developmental biology: 93
  • Year to date:
    • Site-wide: 91,914
  • Since beginning of last month:
    • Site-wide: 97,360

Personalized deep learning of individual immunopeptidomes to identify neoantigens for cancer vaccines

bioinformatics more details view paper
  • Downloaded 1,924 times
  • Download rankings, all-time:
    • Site-wide: 10,574
    • In bioinformatics: 1,194
  • Year to date:
    • Site-wide: 23,849
  • Since beginning of last month:
    • Site-wide: 16,228

Allocation of COVID-19 Vaccines Under Limited Supply

infectious diseases more details view paper
  • Downloaded 1,598 times
  • Download rankings, all-time:
    • Site-wide: 13,900
    • In infectious diseases: 1,715
  • Year to date:
    • Site-wide: 10,640
  • Since beginning of last month:
    • Site-wide: 18,350

A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples

genomics more details view paper
  • Downloaded 1,559 times
  • Download rankings, all-time:
    • Site-wide: 14,486
    • In genomics: 1,425
  • Year to date:
    • Site-wide: 3,703
  • Since beginning of last month:
    • Site-wide: 40,336

A Comprehensive Multi-Center Cross-platform Benchmarking Study of Single-cell RNA Sequencing Using Reference Samples

genomics more details view paper
  • Downloaded 1,387 times
  • Download rankings, all-time:
    • Site-wide: 17,454
    • In genomics: 1,667
  • Year to date:
    • Site-wide: 17,728
  • Since beginning of last month:
    • Site-wide: 25,123

The Big Five, Self-efficacy, and Self-control in Boxers

scientific communication and education more details view paper
  • Downloaded 1,369 times
  • Download rankings, all-time:
    • Site-wide: 17,775
    • In scientific communication and education: 136
  • Year to date:
    • Site-wide: 27,517
  • Since beginning of last month:
    • Site-wide: 27,504

ŌvSim: a Simulation of the Population Dynamics of Mammalian Ovarian Follicles

physiology more details view paper
  • Downloaded 1,239 times
  • Download rankings, all-time:
    • Site-wide: 20,630
    • In physiology: 57
  • Year to date:
    • Site-wide: 79,231
  • Since beginning of last month:
    • Site-wide: 92,404

Low-Bias Amplification for Robust DNA Data Readout

synthetic biology more details view paper
  • Downloaded 1,120 times
  • Download rankings, all-time:
    • Site-wide: 24,057
    • In synthetic biology: 305
  • Year to date:
    • Site-wide: 54,729
  • Since beginning of last month:
    • Site-wide: 79,510

Single-cell transcriptome analysis reveals estrogen signaling augments the mitochondrial folate pathway to coordinately fuel purine and polyamine synthesis in breast cancer cells

genomics more details view paper
  • Downloaded 1,104 times
  • Download rankings, all-time:
    • Site-wide: 24,606
    • In genomics: 2,243
  • Year to date:
    • Site-wide: 140,897
  • Since beginning of last month:
    • Site-wide: 138,107

Stem cell mitotic drive ensures asymmetric epigenetic inheritance

developmental biology more details view paper
  • Downloaded 1,095 times
  • Download rankings, all-time:
    • Site-wide: 24,889
    • In developmental biology: 438
  • Year to date:
    • Site-wide: 97,653
  • Since beginning of last month:
    • Site-wide: 93,123

Identifying strategies to target the metabolic flexibility of tumours

cancer biology more details view paper
  • Downloaded 1,082 times
  • Download rankings, all-time:
    • Site-wide: 25,403
    • In cancer biology: 637
  • Year to date:
    • Site-wide: 47,708
  • Since beginning of last month:
    • Site-wide: 50,938

A Pairwise Distance Distribution Correction (DDC) algorithm to eliminate blinking-caused artifacts in super-resolution microscopy

biophysics more details view paper
  • Downloaded 1,061 times
  • Download rankings, all-time:
    • Site-wide: 26,187
    • In biophysics: 725
  • Year to date:
    • Site-wide: 36,142
  • Since beginning of last month:
    • Site-wide: 45,882

Mapping and Inheritance analysis of a novel dominant rice male sterility mutant, OsDMS-1

genetics more details view paper
  • Downloaded 831 times
  • Download rankings, all-time:
    • Site-wide: 37,397
    • In genetics: 1,633
  • Year to date:
    • Site-wide: 86,189
  • Since beginning of last month:
    • Site-wide: 50,526

GeneQC: A quality control tool for gene expression estimation based on RNA-sequencing reads mapping

bioinformatics more details view paper
  • Downloaded 787 times
  • Download rankings, all-time:
    • Site-wide: 40,460
    • In bioinformatics: 4,274
  • Year to date:
    • Site-wide: 116,619
  • Since beginning of last month:
    • Site-wide: 132,125

Knowledge about benefits and risks of undergoing cataract surgery among cataract patients in Southern China

ophthalmology more details view paper
  • Downloaded 767 times
  • Download rankings, all-time:
    • Site-wide: 42,023
    • In ophthalmology: 18
  • Year to date:
    • Site-wide: 24,805
  • Since beginning of last month:
    • Site-wide: 16,870

Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells

biophysics more details view paper
  • Downloaded 765 times
  • Download rankings, all-time:
    • Site-wide: 42,185
    • In biophysics: 1,354
  • Year to date:
    • Site-wide: 16,613
  • Since beginning of last month:
    • Site-wide: 6,556

Chest Computed Tomography for the Diagnosis of Patients with Coronavirus Disease 2019 (COVID-19): A Rapid Review and Meta-Analysis

radiology and imaging more details view paper
  • Downloaded 654 times
  • Download rankings, all-time:
    • Site-wide: 52,427
    • In radiology and imaging: 91
  • Year to date:
    • Site-wide: 121,198
  • Since beginning of last month:
    • Site-wide: 136,796

Instructive starPEG-Heparin biohybrid 3D cultures for modeling human neural stem cell plasticity, neurogenesis, and neurodegeneration

neuroscience more details view paper
  • Downloaded 648 times
  • Download rankings, all-time:
    • Site-wide: 53,013
    • In neuroscience: 7,476
  • Year to date:
    • Site-wide: 90,894
  • Since beginning of last month:
    • Site-wide: 106,834

Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning

pathology more details view paper
  • Downloaded 643 times
  • Download rankings, all-time:
    • Site-wide: 53,597
    • In pathology: 252
  • Year to date:
    • Site-wide: 115,033
  • Since beginning of last month:
    • Site-wide: 143,831

A novel long noncoding RNA LINC00844 regulates prostate cancer cell migration and invasion through androgen receptor signaling

cancer biology more details view paper
  • Downloaded 599 times
  • Download rankings, all-time:
    • Site-wide: 58,828
    • In cancer biology: 1,691
  • Year to date:
    • Site-wide: 133,106
  • Since beginning of last month:
    • Site-wide: 152,384

A tale of winglets: evolution of flight morphology in stick insects

evolutionary biology more details view paper
  • Downloaded 591 times
  • Download rankings, all-time:
    • Site-wide: 59,887
    • In evolutionary biology: 2,929
  • Year to date:
    • Site-wide: 109,786
  • Since beginning of last month:
    • Site-wide: 141,663

A Genetically Encoded Trimethylsilyl 1D 1H-NMR Probe for Conformation Change in Large Membrane Protein Complexes

biochemistry more details view paper
  • Downloaded 558 times
  • Download rankings, all-time:
    • Site-wide: 64,244
    • In biochemistry: 1,711
  • Year to date:
    • Site-wide: 89,524
  • Since beginning of last month:
    • Site-wide: 88,654

A human antibody with blocking activity to RBD proteins of multiple SARS-CoV-2 variants including B.1.351 showed potent prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus macaques

microbiology more details view paper
  • Downloaded 538 times
  • Download rankings, all-time:
    • Site-wide: 67,125
    • In microbiology: 4,304
  • Year to date:
    • Site-wide: 14,223
  • Since beginning of last month:
    • Site-wide: 76,566

Circular RNAs regulate cancer stem cells by FMRP against CCAR1 complex in hepatocellular carcinoma

cancer biology more details view paper
  • Downloaded 528 times
  • Download rankings, all-time:
    • Site-wide: 68,601
    • In cancer biology: 1,974
  • Year to date:
    • Site-wide: 103,319
  • Since beginning of last month:
    • Site-wide: 68,041

Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 524 times
  • Download rankings, all-time:
    • Site-wide: 69,200
    • In microbiology: 4,466
  • Year to date:
    • Site-wide: 14,813
  • Since beginning of last month:
    • Site-wide: 63,137

A probabilistic model-based bi-clustering method for single-cell transcriptomic data analysis

bioinformatics more details view paper
  • Downloaded 515 times
  • Download rankings, all-time:
    • Site-wide: 70,649
    • In bioinformatics: 6,668
  • Year to date:
    • Site-wide: 148,774
  • Since beginning of last month:
    • Site-wide: 117,348

Asymmetric histone inheritance regulates stem cell fate in Drosophila midgut

developmental biology more details view paper
  • Downloaded 505 times
  • Download rankings, all-time:
    • Site-wide: 72,216
    • In developmental biology: 1,823
  • Year to date:
    • Site-wide: 75,307
  • Since beginning of last month:
    • Site-wide: 47,999

RECTA: Regulon Identification Based on Comparative Genomics and Transcriptomics Analysis

systems biology more details view paper
  • Downloaded 471 times
  • Download rankings, all-time:
    • Site-wide: 78,077
    • In systems biology: 1,750
  • Year to date:
    • Site-wide: 144,308
  • Since beginning of last month:
    • Site-wide: 134,136

Distinct pattern of autofluorescence of the skin and fingernails of acute ischemic stroke patients: A novel diagnostic biomarker for acute ischemic stroke

neuroscience more details view paper
  • Downloaded 453 times
  • Download rankings, all-time:
    • Site-wide: 81,485
    • In neuroscience: 12,024
  • Year to date:
    • Site-wide: 119,213
  • Since beginning of last month:
    • Site-wide: 78,520

Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8

biochemistry more details view paper
  • Downloaded 390 times
  • Download rankings, all-time:
    • Site-wide: 94,606
    • In biochemistry: 2,725
  • Year to date:
    • Site-wide: 23,449
  • Since beginning of last month:
    • Site-wide: 46,971

Characterization of histone inheritance patterns in the Drosophila female germline

developmental biology more details view paper
  • Downloaded 381 times
  • Download rankings, all-time:
    • Site-wide: 96,533
    • In developmental biology: 2,611
  • Year to date:
    • Site-wide: 90,294
  • Since beginning of last month:
    • Site-wide: 118,066

Relationship between ecological stoichiometry and community diversity of plant ecosystems in the upper reaches of the Tarim River, China

ecology more details view paper
  • Downloaded 372 times
  • Download rankings, all-time:
    • Site-wide: 98,540
    • In ecology: 2,808
  • Year to date:
    • Site-wide: 115,709
  • Since beginning of last month:
    • Site-wide: 117,427

Green autofluorescence intensity of skin and fingernails: A novel biomarker for non-invasive evaluation of pathological state of blood vessels

pathology more details view paper
  • Downloaded 357 times
  • Download rankings, all-time:
    • Site-wide: 102,088
    • In pathology: 541
  • Year to date:
    • Site-wide: 141,661
  • Since beginning of last month:
    • Site-wide: 121,376

Mixed Culture of Bacterial Cell for Large Scale DNA Storage

molecular biology more details view paper
  • Downloaded 350 times
  • Download rankings, all-time:
    • Site-wide: 103,941
    • In molecular biology: 3,089
  • Year to date:
    • Site-wide: 112,241
  • Since beginning of last month:
    • Site-wide: 108,423

A Multi-center Cross-platform Single-cell RNA Sequencing Reference Dataset

bioinformatics more details view paper
  • Downloaded 346 times
  • Download rankings, all-time:
    • Site-wide: 104,711
    • In bioinformatics: 8,873
  • Year to date:
    • Site-wide: 92,187
  • Since beginning of last month:
    • Site-wide: 108,839

Trabeculae microstructure parameters serve as effective predictors for marginal bone loss of dental implant in the mandible

dentistry and oral medicine more details view paper
  • Downloaded 321 times
  • Download rankings, all-time:
    • Site-wide: 111,173
    • In dentistry and oral medicine: 85
  • Year to date:
    • Site-wide: 74,938
  • Since beginning of last month:
    • Site-wide: 131,403

Differential condensation of sister chromatids coordinates with Cdc6 to ensure distinct cell cycle progression in Drosophila male germline stem cell lineage

developmental biology more details view paper
  • Downloaded 320 times
  • Download rankings, all-time:
    • Site-wide: 111,236
    • In developmental biology: 3,038
  • Year to date:
    • Site-wide: 31,356
  • Since beginning of last month:
    • Site-wide: 21,513

Associated habitat and suitability modeling of goldenseal (Hydrastis canadensis L.) in Pennsylvania: explaining and predicting species distribution in a northern edge of range state

ecology more details view paper
  • Downloaded 312 times
  • Download rankings, all-time:
    • Site-wide: 113,276
    • In ecology: 3,465
  • Year to date:
    • Site-wide: 119,581
  • Since beginning of last month:
    • Site-wide: 102,952

Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development

cancer biology more details view paper
  • Downloaded 305 times
  • Download rankings, all-time:
    • Site-wide: 115,165
    • In cancer biology: 3,486
  • Year to date:
    • Site-wide: 75,386
  • Since beginning of last month:
    • Site-wide: 99,441

Prevalence, incidence and risk factors for myopia among urban and rural children in southern China: protocol for a school-based cohort study

ophthalmology more details view paper
  • Downloaded 298 times
  • Download rankings, all-time:
    • Site-wide: 116,994
    • In ophthalmology: 128
  • Year to date:
    • Site-wide: 34,578
  • Since beginning of last month:
    • Site-wide: 63,204

RASSF1A independence and early Galectin-1 upregulation in PIK3CA induced hepatocarcinogenesis: new therapeutic venues

pathology more details view paper
  • Downloaded 221 times
  • Download rankings, all-time:
    • Site-wide: 137,205
    • In pathology: 795
  • Year to date:
    • Site-wide: 51,431
  • Since beginning of last month:
    • Site-wide: 111,085

Algorithm optimization for weighted gene co-expression network analysis: accelerating the calculation of Topology Overlap Matrices with OpenMP and SQLite

bioinformatics more details view paper
  • Downloaded 197 times
  • Download rankings, all-time:
    • Site-wide: 143,035
    • In bioinformatics: 11,077
  • Year to date:
    • Site-wide: 59,105
  • Since beginning of last month:
    • Site-wide: 100,723

The Human walking kinematic model combined with upper and lower limb movement

biophysics more details view paper
  • Downloaded 189 times
  • Download rankings, all-time:
    • Site-wide: 145,059
    • In biophysics: 5,527
  • Year to date:
    • Site-wide: 62,334
  • Since beginning of last month:
    • Site-wide: 49,159

Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retina

genomics more details view paper
  • Downloaded 186 times
  • Download rankings, all-time:
    • Site-wide: 145,571
    • In genomics: 7,504
  • Year to date:
    • Site-wide: 137,273
  • Since beginning of last month:
    • Site-wide: 151,221

Sleep disturbances and related factors among preschool children in rural areas of China: a cross-sectional study

epidemiology more details view paper
  • Downloaded 181 times
  • Download rankings, all-time:
    • Site-wide: 146,737
    • In epidemiology: 6,101
  • Year to date:
    • Site-wide: 91,056
  • Since beginning of last month:
    • Site-wide: 76,707

Trends and Patterns of Opioid Epidemic: A Large-Scale Retrospective Study of Hospital Visits with Opioid Poisoning in New York State, 2010-2016

public and global health more details view paper
  • Downloaded 171 times
  • Download rankings, all-time:
    • Site-wide: 148,941
    • In public and global health: 2,053
  • Year to date:
    • Site-wide: 108,299
  • Since beginning of last month:
    • Site-wide: 95,027

Does Obstructive sleep apnea increase the risk of Parkinson Disease? A systematic review and meta-analysis.

epidemiology more details view paper
  • Downloaded 156 times
  • Download rankings, all-time:
    • Site-wide: 151,885
    • In epidemiology: 6,290
  • Year to date:
    • Site-wide: 112,055
  • Since beginning of last month:
    • Site-wide: 85,050

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