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Author: David J. Adams

Rankings

  • All-time downloads: 28,308 (rank: 7,175 )
  • Categories:
    • bioinformatics: 4,650 (rank: 3,012 (tie) )
    • cancer biology: 7,780 (rank: 336 )
    • cell biology: 1,430 (rank: 6,449 (tie) )
    • genetic and genomic medicine: 159 (rank: 12,690 (tie) )
    • genetics: 1,675 (rank: 11,802 (tie) )
    • genomics: 6,799 (rank: 3,507 (tie) )
    • immunology: 1,097 (rank: 11,826 (tie) )
    • microbiology: 714 (rank: 24,283 (tie) )
    • molecular biology: 319 (rank: 22,226 (tie) )
    • neuroscience: 169 (rank: 84,667 (tie) )
    • pharmacology and toxicology: 75 (rank: 9,203 (tie) )
    • systems biology: 3,441 (rank: 1,333 (tie) )

Downloads per author, site-wide

Preprints

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

cancer biology more details view paper
  • Downloaded 6,276 times
  • Download rankings, all-time:
    • Site-wide: 1,889
    • In cancer biology: 20
  • Year to date:
    • Site-wide: 5,296
  • Since beginning of last month:
    • Site-wide: 17,783

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

bioinformatics more details view paper
  • Downloaded 2,160 times
  • Download rankings, all-time:
    • Site-wide: 8,438
    • In bioinformatics: 940
  • Year to date:
    • Site-wide: 45,705
  • Since beginning of last month:
    • Site-wide: 80,534

An Atlas of Human and Murine Genetic Influences on Osteoporosis

genomics more details view paper
  • Downloaded 1,706 times
  • Download rankings, all-time:
    • Site-wide: 11,930
    • In genomics: 1,197
  • Year to date:
    • Site-wide: 43,250
  • Since beginning of last month:
    • Site-wide: 64,770

Multiple laboratory mouse reference genomes define strain specific haplotypes and novel functional loci

genomics more details view paper
  • Downloaded 1,556 times
  • Download rankings, all-time:
    • Site-wide: 13,606
    • In genomics: 1,369
  • Year to date:
    • Site-wide: 77,859
  • Since beginning of last month:
    • Site-wide: None

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

cell biology more details view paper
  • Downloaded 1,430 times
  • Download rankings, all-time:
    • Site-wide: 15,564
    • In cell biology: 447
  • Year to date:
    • Site-wide: 118,343
  • Since beginning of last month:
    • Site-wide: 129,574

Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease

systems biology more details view paper
  • Downloaded 1,300 times
  • Download rankings, all-time:
    • Site-wide: 17,948
    • In systems biology: 333
  • Year to date:
    • Site-wide: 11,987
  • Since beginning of last month:
    • Site-wide: 35,050

Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

bioinformatics more details view paper
  • Downloaded 1,215 times
  • Download rankings, all-time:
    • Site-wide: 19,839
    • In bioinformatics: 2,259
  • Year to date:
    • Site-wide: 4,226
  • Since beginning of last month:
    • Site-wide: 8,564

Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines

systems biology more details view paper
  • Downloaded 1,154 times
  • Download rankings, all-time:
    • Site-wide: 21,408
    • In systems biology: 403
  • Year to date:
    • Site-wide: 5,515
  • Since beginning of last month:
    • Site-wide: 8,066

Human and mouse essentiality screens as a resource for disease gene discovery

genomics more details view paper
  • Downloaded 1,108 times
  • Download rankings, all-time:
    • Site-wide: 22,751
    • In genomics: 2,139
  • Year to date:
    • Site-wide: 71,093
  • Since beginning of last month:
    • Site-wide: 95,942

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

immunology more details view paper
  • Downloaded 1,097 times
  • Download rankings, all-time:
    • Site-wide: 23,094
    • In immunology: 787
  • Year to date:
    • Site-wide: 104,842
  • Since beginning of last month:
    • Site-wide: 138,021

Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation, and homozygous truncating mutations

genomics more details view paper
  • Downloaded 993 times
  • Download rankings, all-time:
    • Site-wide: 26,853
    • In genomics: 2,428
  • Year to date:
    • Site-wide: 101,250
  • Since beginning of last month:
    • Site-wide: 129,087

Genomic determinants of protein abundance variation in colorectal cancer cells

systems biology more details view paper
  • Downloaded 987 times
  • Download rankings, all-time:
    • Site-wide: 27,086
    • In systems biology: 533
  • Year to date:
    • Site-wide: 117,047
  • Since beginning of last month:
    • Site-wide: 137,232

A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination

cancer biology more details view paper
  • Downloaded 933 times
  • Download rankings, all-time:
    • Site-wide: 29,339
    • In cancer biology: 753
  • Year to date:
    • Site-wide: 66,620
  • Since beginning of last month:
    • Site-wide: 88,135

VCF/Plotein: A web application to facilitate the clinical interpretation of genetic and genomic variants from exome sequencing projects

bioinformatics more details view paper
  • Downloaded 828 times
  • Download rankings, all-time:
    • Site-wide: 34,651
    • In bioinformatics: 3,756
  • Year to date:
    • Site-wide: 74,306
  • Since beginning of last month:
    • Site-wide: 113,355

A resource of targeted mutant mouse lines for 5,061 genes

genetics more details view paper
  • Downloaded 800 times
  • Download rankings, all-time:
    • Site-wide: 36,436
    • In genetics: 1,614
  • Year to date:
    • Site-wide: 42,806
  • Since beginning of last month:
    • Site-wide: 36,664

Multi-site clonality analyses uncovers pervasive subclonal heterogeneity and branching evolution across melanoma metastases

genomics more details view paper
  • Downloaded 782 times
  • Download rankings, all-time:
    • Site-wide: 37,620
    • In genomics: 3,096
  • Year to date:
    • Site-wide: 80,349
  • Since beginning of last month:
    • Site-wide: 65,754

Accelerating functional gene discovery in osteoarthritis

genetics more details view paper
  • Downloaded 716 times
  • Download rankings, all-time:
    • Site-wide: 42,499
    • In genetics: 1,872
  • Year to date:
    • Site-wide: 76,672
  • Since beginning of last month:
    • Site-wide: 69,573

Novel gut pathobionts confound results in a widely used mouse model of human inflammatory disease

microbiology more details view paper
  • Downloaded 714 times
  • Download rankings, all-time:
    • Site-wide: 42,682
    • In microbiology: 2,563
  • Year to date:
    • Site-wide: 7,233
  • Since beginning of last month:
    • Site-wide: 3,550

Tumour gene expression signature in primary melanoma predicts long-term outcomes: A prospective multicentre study

bioinformatics more details view paper
  • Downloaded 447 times
  • Download rankings, all-time:
    • Site-wide: 75,370
    • In bioinformatics: 6,967
  • Year to date:
    • Site-wide: 79,975
  • Since beginning of last month:
    • Site-wide: 56,409

Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for Saturation Genome Editing and other Deep Mutational Scanning experiments

genomics more details view paper
  • Downloaded 355 times
  • Download rankings, all-time:
    • Site-wide: 93,774
    • In genomics: 5,843
  • Year to date:
    • Site-wide: 20,488
  • Since beginning of last month:
    • Site-wide: 58,273

Mutagenic mechanisms of cancer-associated DNA polymerase ε alleles

molecular biology more details view paper
  • Downloaded 319 times
  • Download rankings, all-time:
    • Site-wide: 102,174
    • In molecular biology: 3,050
  • Year to date:
    • Site-wide: 102,841
  • Since beginning of last month:
    • Site-wide: 115,150

Hotspot KRAS mutations in brain metastases at the first metastatic recurrence of cutaneous melanoma

genomics more details view paper
  • Downloaded 299 times
  • Download rankings, all-time:
    • Site-wide: 106,862
    • In genomics: 6,307
  • Year to date:
    • Site-wide: 114,758
  • Since beginning of last month:
    • Site-wide: 128,008

A genome-wide screen in mice to identify cell-extrinsic regulators of pulmonary metastatic colonisation

cancer biology more details view paper
  • Downloaded 292 times
  • Download rankings, all-time:
    • Site-wide: 108,692
    • In cancer biology: 3,301
  • Year to date:
    • Site-wide: 114,637
  • Since beginning of last month:
    • Site-wide: 116,745

PREDICTIVE IMMUNE CHECKPOINT BLOCKADE CLASSIFIERS DISTINGUISHING MONO- VERSUS COMBINATION THERAPY REQUIREMENT

cancer biology more details view paper
  • Downloaded 279 times
  • Download rankings, all-time:
    • Site-wide: 112,082
    • In cancer biology: 3,397
  • Year to date:
    • Site-wide: 90,383
  • Since beginning of last month:
    • Site-wide: 99,464

Analgesic α-conotoxins modulate GIRK1/2 channels via GABAB receptor activation and reduce neuroexcitability

neuroscience more details view paper
  • Downloaded 169 times
  • Download rankings, all-time:
    • Site-wide: 139,939
    • In neuroscience: 20,912
  • Year to date:
    • Site-wide: 84,765
  • Since beginning of last month:
    • Site-wide: 79,612

Fine-mapping of melanoma-associated genomic regions identifies novel causal SNPs in the MTAP/CDKN2A and CASP8 loci

genetic and genomic medicine more details view paper
  • Downloaded 159 times
  • Download rankings, all-time:
    • Site-wide: 142,226
    • In genetic and genomic medicine: 827
  • Year to date:
    • Site-wide: 56,481
  • Since beginning of last month:
    • Site-wide: 37,985

The production of 4,182 mouse lines identifies experimental and biological variables impacting Cas9-mediated mutant mouse line production

genetics more details view paper
  • Downloaded 159 times
  • Download rankings, all-time:
    • Site-wide: 142,270
    • In genetics: 5,641
  • Year to date:
    • Site-wide: 56,430
  • Since beginning of last month:
    • Site-wide: 4,841

{micro}-Theraphotoxin-Pn3a inhibition of Cav3.3 channels reveals a novel isoform-selective drug binding site

pharmacology and toxicology more details view paper
  • Downloaded 75 times
  • Download rankings, all-time:
    • Site-wide: 156,588
    • In pharmacology and toxicology: 1,374
  • Year to date:
    • Site-wide: 108,316
  • Since beginning of last month:
    • Site-wide: 14,775

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