Author: Dennis van der Meer

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Preprints

The genetic architecture of the human cerebral cortex

• Downloaded 8,585 times
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  • Site-wide: 1,682
  • In genetics: 35
• Year to date:
  • Site-wide: 12,260
• Since beginning of last month:
  • Site-wide: 26,297

Greater male than female variability in regional brain structure across the lifespan

• Downloaded 3,982 times
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  • Site-wide: 4,833
  • In neuroscience: 359
• Year to date:
  • Site-wide: 88,017
• Since beginning of last month:
  • Site-wide: 45,926

Genetics of brain age suggest an overlap with common brain disorders

• Downloaded 3,155 times
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  • Site-wide: 6,819
  • In neuroscience: 586
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 26,383

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

• Downloaded 2,855 times
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  • Site-wide: 7,832
  • In genetics: 294
• Year to date:
  • Site-wide: 11,906
• Since beginning of last month:
  • Site-wide: 3,582

Oxytocin gene networks in the human brain: A gene expression and large-scale fMRI meta-analysis study

• Downloaded 1,678 times
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  • Site-wide: 17,657
  • In neuroscience: 1,954
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 59,889

Cerebellar grey matter volume is associated with cognitive function and psychopathology in adolescence

• Downloaded 1,676 times
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  • Site-wide: 17,704
  • In neuroscience: 1,941
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 144,620

Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium

• Downloaded 1,611 times
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  • Site-wide: 18,845
  • In neuroscience: 2,113
• Year to date:
  • Site-wide: 81,089
• Since beginning of last month:
  • Site-wide: 154,356

Phenotypically independent mental health symptom profiles are genetically related

• Downloaded 1,197 times
• Download rankings, all-time:
  • Site-wide: 30,232
  • In psychiatry and clinical psychology: 123
• Year to date:
  • Site-wide: 91,170
• Since beginning of last month:
  • Site-wide: 123,869

Vaccination history for diphtheria and tetanus is associated with less severe COVID-19

• Downloaded 1,160 times
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  • Site-wide: 31,802
  • In epidemiology: 1,806
• Year to date:
  • Site-wide: 36,313
• Since beginning of last month:
  • Site-wide: 42,604

Predicting cognitive and mental health traits and their polygenic architecture using large-scale brain connectomics

• Downloaded 1,119 times
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  • Site-wide: 33,669
  • In neuroscience: 4,313
• Year to date:
  • Site-wide: 141,393
• Since beginning of last month:
  • Site-wide: 21,750

Planar cell polarity pathway and development of the human visual cortex

• Downloaded 1,010 times
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  • Site-wide: 39,339
  • In neuroscience: 5,184
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 93,696

Women’s brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer’s disease

• Downloaded 1,006 times
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  • Site-wide: 39,587
  • In neuroscience: 5,109
• Year to date:
  • Site-wide: 109,539
• Since beginning of last month:
  • Site-wide: 126,985

The genetic architecture of human cortical folding

• Downloaded 910 times
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  • Site-wide: 46,244
  • In genomics: 3,473
• Year to date:
  • Site-wide: 122,705
• Since beginning of last month:
  • Site-wide: 102,941

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy and improves prediction

• Downloaded 877 times
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  • Site-wide: 49,002
  • In genetics: 1,971
• Year to date:
  • Site-wide: 14,760
• Since beginning of last month:
  • Site-wide: 20,845

The genetic architecture of human brainstem structures and their involvement in common brain disorders

• Downloaded 875 times
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  • Site-wide: 49,212
  • In neuroscience: 6,496
• Year to date:
  • Site-wide: 178,948
• Since beginning of last month:
  • Site-wide: 126,891

Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

• Downloaded 834 times
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  • Site-wide: 52,856
  • In genetics: 2,072
• Year to date:
  • Site-wide: 90,625
• Since beginning of last month:
  • Site-wide: 121,908

Making the MOSTest of imaging genetics

• Downloaded 814 times
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  • Site-wide: 54,731
  • In neuroscience: 7,413
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 187,474

Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes

• Downloaded 794 times
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  • Site-wide: 56,848
  • In genetics: 2,190
• Year to date:
  • Site-wide: 174,848
• Since beginning of last month:
  • Site-wide: 151,136

Genome-wide association analysis of the human thalamus identifies novel genomic loci and reveals genetic overlap with distinct cortical regions and ten brain disorders

• Downloaded 782 times
• Download rankings, all-time:
  • Site-wide: 58,107
  • In genetic and genomic medicine: 365
• Year to date:
  • Site-wide: 92,095
• Since beginning of last month:
  • Site-wide: 167,994

Associations between psychiatric disorders, COVID-19 testing probability and COVID-19 testing results: Findings from a population-based study

• Downloaded 771 times
• Download rankings, all-time:
  • Site-wide: 59,442
  • In psychiatry and clinical psychology: 269
• Year to date:
  • Site-wide: 132,804
• Since beginning of last month:
  • Site-wide: 188,271

Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits

• Downloaded 759 times
• Download rankings, all-time:
  • Site-wide: 60,777
  • In neuroscience: 8,336
• Year to date:
  • Site-wide: 138,768
• Since beginning of last month:
  • Site-wide: 145,715

Improved prediction of schizophrenia by leveraging genetic overlap with brain morphology

• Downloaded 700 times
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  • Site-wide: 68,330
  • In psychiatry and clinical psychology: 312
• Year to date:
  • Site-wide: 91,900
• Since beginning of last month:
  • Site-wide: 161,094

Genetic overlap between multivariate measures of human functional brain connectivity and psychiatric disorders

• Downloaded 669 times
• Download rankings, all-time:
  • Site-wide: 72,683
  • In genetic and genomic medicine: 473
• Year to date:
  • Site-wide: 96,168
• Since beginning of last month:
  • Site-wide: 35,776

Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multi-sample diffusion tensor imaging study

• Downloaded 667 times
• Download rankings, all-time:
  • Site-wide: 73,030
  • In neuroscience: 10,279
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 181,298

The dark side of the mean: brain structural heterogeneity in schizophrenia and its polygenic risk.

• Downloaded 644 times
• Download rankings, all-time:
  • Site-wide: 76,625
  • In neuroscience: 10,928
• Year to date:
  • Site-wide: 101,521
• Since beginning of last month:
  • Site-wide: 118,774

Multivariate genome-wide association study on tissue-sensitive diffusion metrics identifies key molecular pathways for axonal growth, synaptogenesis, and astrocyte-mediated neuroinflammation

• Downloaded 643 times
• Download rankings, all-time:
  • Site-wide: 76,832
  • In genetics: 2,959
• Year to date:
  • Site-wide: 95,780
• Since beginning of last month:
  • Site-wide: 71,367

Population-based neuroimaging reveals traces of childbirth in the maternal brain

• Downloaded 633 times
• Download rankings, all-time:
  • Site-wide: 78,323
  • In neuroscience: 11,070
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 154,017

Genetic control of variability in subcortical and intracranial volumes

• Downloaded 608 times
• Download rankings, all-time:
  • Site-wide: 82,380
  • In neuroscience: 11,658
• Year to date:
  • Site-wide: 167,091
• Since beginning of last month:
  • Site-wide: 142,295

Differences in directed functional brain connectivity related to age, sex and mental health

• Downloaded 602 times
• Download rankings, all-time:
  • Site-wide: 83,534
  • In neuroscience: 11,826
• Year to date:
  • Site-wide: 142,806
• Since beginning of last month:
  • Site-wide: 98,089

Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories

• Downloaded 538 times
• Download rankings, all-time:
  • Site-wide: 96,020
  • In neuroscience: 13,689
• Year to date:
  • Site-wide: 163,919
• Since beginning of last month:
  • Site-wide: 198,764

Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank

• Downloaded 496 times
• Download rankings, all-time:
  • Site-wide: 105,384
  • In genetic and genomic medicine: 680
• Year to date:
  • Site-wide: 182,125
• Since beginning of last month:
  • Site-wide: 188,792

Genetic and phenotypic associations between brain imaging, psychopathology and educational attainment in children aged 9-11

• Downloaded 460 times
• Download rankings, all-time:
  • Site-wide: 114,100
  • In psychiatry and clinical psychology: 621
• Year to date:
  • Site-wide: 43,291
• Since beginning of last month:
  • Site-wide: 50,368

Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

• Downloaded 443 times
• Download rankings, all-time:
  • Site-wide: 118,544
  • In neuroscience: 17,144
• Year to date:
  • Site-wide: 135,979
• Since beginning of last month:
  • Site-wide: 215,506

Population-based body-brain mapping links brain morphology and body composition

• Downloaded 427 times
• Download rankings, all-time:
  • Site-wide: 122,606
  • In neuroscience: 17,923
• Year to date:
  • Site-wide: 110,936
• Since beginning of last month:
  • Site-wide: 186,242

The role of liver fat in cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition

• Downloaded 384 times
• Download rankings, all-time:
  • Site-wide: 135,085
  • In genomics: 7,395
• Year to date:
  • Site-wide: 41,010
• Since beginning of last month:
  • Site-wide: 40,200

Genetic overlap between Alzheimer's disease and depression mapped onto the brain

• Downloaded 374 times
• Download rankings, all-time:
  • Site-wide: 137,937
  • In genetic and genomic medicine: 961
• Year to date:
  • Site-wide: 123,856
• Since beginning of last month:
  • Site-wide: 195,155

Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents

• Downloaded 368 times
• Download rankings, all-time:
  • Site-wide: 139,827
  • In neuroscience: 20,299
• Year to date:
  • Site-wide: 184,671
• Since beginning of last month:
  • Site-wide: 215,362

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

• Downloaded 357 times
• Download rankings, all-time:
  • Site-wide: 143,026
  • In genetics: 5,337
• Year to date:
  • Site-wide: 156,833
• Since beginning of last month:
  • Site-wide: 161,598

Generalization of Cortical MOSTest Genome-Wide Associations Within and Across Samples

• Downloaded 353 times
• Download rankings, all-time:
  • Site-wide: 144,181
  • In genomics: 7,644
• Year to date:
  • Site-wide: 121,183
• Since beginning of last month:
  • Site-wide: 111,036

Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: UK Biobank 18608 example

• Downloaded 299 times
• Download rankings, all-time:
  • Site-wide: 160,664
  • In neuroscience: 23,418
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 214,058

White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging

• Downloaded 299 times
• Download rankings, all-time:
  • Site-wide: 160,505
  • In neuroscience: 23,325
• Year to date:
  • Site-wide: 196,704
• Since beginning of last month:
  • Site-wide: 208,148

Distributed genetic architecture across the hippocampal formation implies common neuropathology across major brain disorders

• Downloaded 282 times
• Download rankings, all-time:
  • Site-wide: 165,664
  • In genetic and genomic medicine: 1,182
• Year to date:
  • Site-wide: 126,036
• Since beginning of last month:
  • Site-wide: 106,076

The Genetic Architecture of Amygdala Nuclei

• Downloaded 253 times
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  • Site-wide: 174,302
  • In genetic and genomic medicine: 1,300
• Year to date:
  • Site-wide: 42,321
• Since beginning of last month:
  • Site-wide: 85,452

A comparison of intracranial volume estimation methods and their cross-sectional and longitudinal associations with age

• Downloaded 210 times
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  • Site-wide: 185,481
  • In neuroscience: 27,254
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 73,731

Brain-wide associations between white matter and agehighlight the role of fornix microstructure in brain age

• Downloaded 206 times
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  • Site-wide: 186,381
  • In neuroscience: 28,876
• Year to date:
  • Site-wide: 9,582
• Since beginning of last month:
  • Site-wide: 11,629

Clustering schizophrenia genes by their temporal expression patterns aids functional interpretation: genetics-based evidence in favor of the two-hit hypothesis

• Downloaded 150 times
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  • Site-wide: 198,597
  • In psychiatry and clinical psychology: 1,385
• Year to date:
  • Site-wide: 148,405
• Since beginning of last month:
  • Site-wide: 84,457

Female-specific factors are associated with cognition in the UK Biobank cohort.

• Downloaded 142 times
• Download rankings, all-time:
  • Site-wide: 200,132
  • In epidemiology: 7,827
• Year to date:
  • Site-wide: 187,647
• Since beginning of last month:
  • Site-wide: 114,290

Efficient meta-analysis of multivariate genome-wide association studies with Meta-MOSTest

• Downloaded 138 times
• Download rankings, all-time:
  • Site-wide: 200,862
  • In bioinformatics: 14,711
• Year to date:
  • Site-wide: 148,495
• Since beginning of last month:
  • Site-wide: 56,432

Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness

• Downloaded 125 times
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  • Site-wide: 203,385
  • In neuroscience: 29,366
• Year to date:
  • Site-wide: 146,726
• Since beginning of last month:
  • Site-wide: 74,027

Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank

• Downloaded 124 times
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  • Site-wide: 203,447
  • In genetic and genomic medicine: 1,610
• Year to date:
  • Site-wide: 49,940
• Since beginning of last month:
  • Site-wide: 51,342

Improved functional mapping with GSA-MiXeR implicates biologically specific gene-sets and estimates enrichment magnitude

• Downloaded 72 times
• Download rankings, all-time:
  • Site-wide: 212,912
  • In psychiatry and clinical psychology: None
• Year to date:
  • Site-wide: 15,602
• Since beginning of last month:
  • Site-wide: 6,428

Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study

• Downloaded 69 times
• Download rankings, all-time:
  • Site-wide: 213,510
  • In genetics: None
• Year to date:
  • Site-wide: 15,736
• Since beginning of last month:
  • Site-wide: 6,984

Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants

• Downloaded 67 times
• Download rankings, all-time:
  • Site-wide: 213,897
  • In radiology and imaging: None
• Year to date:
  • Site-wide: 27,491
• Since beginning of last month:
  • Site-wide: 6,307