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Author: Philip Scheltens

Rankings

  • All-time downloads: 28,181 (rank: 9,189 (tie) )
  • Categories:
    • epidemiology: 399 (rank: 25,752 (tie) )
    • genetic and genomic medicine: 6,493 (rank: 332 (tie) )
    • genetics: 352 (rank: 37,628 (tie) )
    • genomics: 1,028 (rank: 26,667 (tie) )
    • medical ethics: 276 (rank: 146 (tie) )
    • neurology: 13,136 (rank: 114 )
    • neuroscience: 4,096 (rank: 6,857 (tie) )
    • psychiatry and clinical psychology: 534 (rank: 3,626 (tie) )

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Preprints

New insights on the genetic etiology of Alzheimer and related dementia

neurology more details view paper
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Common variants in Alzheimer's disease: Novel association of six genetic variants with AD and risk stratification by polygenic risk scores

genetic and genomic medicine more details view paper
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    • Site-wide: 6,117
    • In genetic and genomic medicine: 28
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Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimers Disease

genetic and genomic medicine more details view paper
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    • In genetic and genomic medicine: 45
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Immune response and endocytosis pathways are associated with the escape of Alzheimer's Disease

genetic and genomic medicine more details view paper
  • Downloaded 922 times
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    • In genetic and genomic medicine: 189
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Data-driven approaches for Tau-PET imaging biomarkers in Alzheimer's disease

neuroscience more details view paper
  • Downloaded 895 times
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    • Site-wide: 38,584
    • In neuroscience: 4,829
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The 100-plus Study of Dutch cognitively healthy centenarians: rationale, design and cohort description

neuroscience more details view paper
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Protective effects of HLA-DRB1*04 subtypes in Parkinson's and Alzheimer's diseases implicate acetylated Tau PHF6 sequences

neurology more details view paper
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Provisional research criteria for the behavioral variant of Alzheimer disease: A systematic review and meta-analysis

neurology more details view paper
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Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

genomics more details view paper
  • Downloaded 669 times
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Cerebrospinal fluid tau levels indicate aberrant neuronal plasticity in Alzheimer disease

neurology more details view paper
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    • In neurology: 186
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The Cognitive-Functional Composite is sensitive to clinical progression in early dementia: longitudinal findings from the Catch-Cog study cohort

neurology more details view paper
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    • In neurology: 185
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Independent information from PET, CSF and plasma biomarkers of tau pathology in Alzheimer's disease

neuroscience more details view paper
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    • Site-wide: 72,729
    • In neuroscience: 10,817
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A metabolite-based machine learning approach to diagnose Alzheimer's-type dementia in blood: Results from the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

psychiatry and clinical psychology more details view paper
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    • Site-wide: 76,593
    • In psychiatry and clinical psychology: 307
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Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer's disease

neurology more details view paper
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    • In neurology: 260
  • Year to date:
    • Site-wide: 126,382
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Neuropathology and cognitive performance in centenarians

neuroscience more details view paper
  • Downloaded 517 times
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    • Site-wide: 80,546
    • In neuroscience: 11,238
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Amyloid-beta CSF/PET discordance vs tau load 5 years later: It takes two to tangle

neurology more details view paper
  • Downloaded 500 times
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    • Site-wide: 83,808
    • In neurology: 274
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    • Site-wide: 149,994
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    • Site-wide: 138,964

Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers

neurology more details view paper
  • Downloaded 490 times
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    • Site-wide: 85,931
    • In neurology: None
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Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics.

neurology more details view paper
  • Downloaded 488 times
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    • Site-wide: 86,176
    • In neurology: 298
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Data-driven detection of latent atrophy factors related to phenotypical variants of posterior cortical atrophy

neuroscience more details view paper
  • Downloaded 448 times
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    • Site-wide: 94,505
    • In neuroscience: 13,272
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Neuropsychological Test Performance of Cognitively Healthy Centenarians: Normative data from the Dutch 100-plus Study

epidemiology more details view paper
  • Downloaded 405 times
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    • Site-wide: 104,547
    • In epidemiology: 4,313
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The effect of Alzheimer's disease-associated genetic variants on longevity

genetic and genomic medicine more details view paper
  • Downloaded 388 times
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    • Site-wide: 108,714
    • In genetic and genomic medicine: 632
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Neuropsychiatric and cognitive symptoms across the Alzheimer's disease clinical spectrum: Cross-sectional and longitudinal associations

neurology more details view paper
  • Downloaded 382 times
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    • In neurology: 420
  • Year to date:
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TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels

genomics more details view paper
  • Downloaded 371 times
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    • Site-wide: 113,036
    • In genomics: 6,324
  • Year to date:
    • Site-wide: 158,125
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    • Site-wide: 142,982

Automated quantification of small vessel disease brain changes on MRI predicts cognitive and functional decline

neuroscience more details view paper
  • Downloaded 362 times
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    • Site-wide: 115,549
    • In neuroscience: 16,836
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    • Site-wide: 108,107
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Contribution of genetic and environmental factors to the onset of preclinical Alzheimer's disease - a monozygotic twin study

neurology more details view paper
  • Downloaded 359 times
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    • Site-wide: 116,269
    • In neurology: 468
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Centenarian Controls Increase Variant Effect-sizes by an average two-fold in an Extreme Case-Extreme Control Analysis of Alzheimer's Disease

genetics more details view paper
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    • Site-wide: 117,226
    • In genetics: 4,468
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    • Site-wide: 180,020
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    • Site-wide: 162,867

Sex-specific metabolic pathways associate with Alzheimer's Disease (AD) endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery (EMIF-AD MBD) cohort

neurology more details view paper
  • Downloaded 337 times
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No proof for retinal amyloid after oral curcumin in amyloid confirmed AD cases

neurology more details view paper
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    • In neurology: 654
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Considerations regarding a diagnosis of Alzheimer's Disease before dementia: a systematic review

medical ethics more details view paper
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    • In medical ethics: 31
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PET and CSF amyloid-β status are differently predicted by patient features: Information from discordant cases

neuroscience more details view paper
  • Downloaded 288 times
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    • Site-wide: 136,344
    • In neuroscience: 19,693
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Amyloid-β PET and CSF in an autopsy confirmed cohort

neurology more details view paper
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    • In neurology: 711
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Differential brain atrophy and neurogenetic profiles in cognitively-defined Alzheimer's disease subgroups

neuroscience more details view paper
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    • In neuroscience: 20,672
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Heterogeneous distribution of tau pathology in the behavioral variant of Alzheimer's disease

neurology more details view paper
  • Downloaded 234 times
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    • Site-wide: 152,213
    • In neurology: 803
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Rare variants in IFFO1, DTNB and NLRC3 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation

neurology more details view paper
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The behavioral variant of Alzheimer's disease does not show a selective loss of Von Economo and phylogenetically related neurons in the anterior cingulate cortex

neurology more details view paper
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Social cognition deficits and its biometric signatures in the behavioral variant of Alzheimer's disease

neurology more details view paper
  • Downloaded 142 times
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    • Site-wide: 174,825
    • In neurology: 1,183
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Differential associations between neocortical tau pathology and blood flow with cognitive deficits in early-onset vs late-onset Alzheimer's disease

neurology more details view paper
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Added diagnostic accuracy after flutemetamol PET scanning in young patients with dementia in an academic memory clinic setting

neurology more details view paper
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    • In neurology: 1,176
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Everyday functioning in a community-based volunteer population: Differences between participant- and study partner-report

neurology more details view paper
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