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Author: Yan Chen

Rankings

  • All-time downloads: 30,458 (rank: 8,488 (tie) )
  • Categories:
    • biochemistry: 1,269 (rank: 5,659 (tie) )
    • bioengineering: 1,352 (rank: 3,559 (tie) )
    • biophysics: 2,025 (rank: 3,129 )
    • cell biology: 226 (rank: 43,506 (tie) )
    • developmental biology: 268 (rank: 20,967 (tie) )
    • epidemiology: 177 (rank: 35,660 (tie) )
    • genetic and genomic medicine: 796 (rank: 6,413 (tie) )
    • genetics: 3,738 (rank: 5,680 (tie) )
    • genomics: 3,190 (rank: 9,168 (tie) )
    • immunology: 425 (rank: 30,050 (tie) )
    • infectious diseases: 1,136 (rank: 30,682 (tie) )
    • microbiology: 3,790 (rank: 5,231 (tie) )
    • molecular biology: 2,372 (rank: 2,534 (tie) )
    • neuroscience: 1,716 (rank: 18,603 (tie) )
    • pathology: 445 (rank: 4,395 (tie) )
    • pharmacology and toxicology: 272 (rank: 7,306 (tie) )
    • physiology: 542 (rank: 4,246 (tie) )
    • respiratory medicine: 2,691 (rank: 478 (tie) )
    • synthetic biology: 547 (rank: 4,676 (tie) )
    • systems biology: 167 (rank: 16,370 (tie) )

Downloads per author, site-wide

Preprints

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

genetics more details view paper
  • Downloaded 3,001 times
  • Download rankings, all-time:
    • Site-wide: 6,551
    • In genetics: 253
  • Year to date:
    • Site-wide: 13,049
  • Since beginning of last month:
    • Site-wide: 20,915

Epidemiological and clinical features of 291 cases with coronavirus disease 2019 in areas adjacent to Hubei, China: a double-center observational study

respiratory medicine more details view paper
  • Downloaded 2,734 times
  • Download rankings, all-time:
    • Site-wide: 7,501
    • In respiratory medicine: 29
  • Year to date:
    • Site-wide: 68,447
  • Since beginning of last month:
    • Site-wide: 77,093

Distinct mutations and lineages of SARS-CoV-2 virus in the early phase of COVID-19 pandemic and subsequent global expansion

genomics more details view paper
  • Downloaded 2,007 times
  • Download rankings, all-time:
    • Site-wide: 11,887
    • In genomics: 1,214
  • Year to date:
    • Site-wide: 16,640
  • Since beginning of last month:
    • Site-wide: 2,273

Large-scale chemical-genetics of the human gut bacterium Bacteroides thetaiotaomicron

microbiology more details view paper
  • Downloaded 1,882 times
  • Download rankings, all-time:
    • Site-wide: 13,075
    • In microbiology: 732
  • Year to date:
    • Site-wide: 72,155
  • Since beginning of last month:
    • Site-wide: 60,697

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

infectious diseases more details view paper
  • Downloaded 1,422 times
  • Download rankings, all-time:
    • Site-wide: 20,049
    • In infectious diseases: 2,704
  • Year to date:
    • Site-wide: 5,676
  • Since beginning of last month:
    • Site-wide: 1,851

Endocytic Clathrin Coats Develop Curvature at Early Stages of Their Formation

biophysics more details view paper
  • Downloaded 1,120 times
  • Download rankings, all-time:
    • Site-wide: 29,018
    • In biophysics: 793
  • Year to date:
    • Site-wide: 43,542
  • Since beginning of last month:
    • Site-wide: 77,778

Functional connectivity alterations of the temporal lobe and hippocampus in semantic dementia and Alzheimer’s disease

neuroscience more details view paper
  • Downloaded 1,018 times
  • Download rankings, all-time:
    • Site-wide: 33,513
    • In neuroscience: 3,974
  • Year to date:
    • Site-wide: 119,105
  • Since beginning of last month:
    • Site-wide: 158,829

Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor

molecular biology more details view paper
  • Downloaded 878 times
  • Download rankings, all-time:
    • Site-wide: 41,652
    • In molecular biology: 1,175
  • Year to date:
    • Site-wide: 55,522
  • Since beginning of last month:
    • Site-wide: 16,787

Whole-exome sequencing identified rare variants associated with body length and girth in cattle

genetics more details view paper
  • Downloaded 869 times
  • Download rankings, all-time:
    • Site-wide: 42,347
    • In genetics: 1,758
  • Year to date:
    • Site-wide: 68,260
  • Since beginning of last month:
    • Site-wide: 78,592

Genome-scale metabolic rewiring to achieve predictable titers rates and yield of a non-native product at scale

bioengineering more details view paper
  • Downloaded 842 times
  • Download rankings, all-time:
    • Site-wide: 44,450
    • In bioengineering: 786
  • Year to date:
    • Site-wide: 135,324
  • Since beginning of last month:
    • Site-wide: 128,453

Chemoinformatic-guided engineering of polyketide synthases

biochemistry more details view paper
  • Downloaded 782 times
  • Download rankings, all-time:
    • Site-wide: 49,526
    • In biochemistry: 1,142
  • Year to date:
    • Site-wide: 146,471
  • Since beginning of last month:
    • Site-wide: 176,711

Structural basis for the therapeutic advantage of dual and triple agonists at the human GIP, GLP-1 or GCG receptors

molecular biology more details view paper
  • Downloaded 755 times
  • Download rankings, all-time:
    • Site-wide: 52,052
    • In molecular biology: 1,843
  • Year to date:
    • Site-wide: 15,154
  • Since beginning of last month:
    • Site-wide: 12,180

Improving the Efficiency of Genomic Selection in Chinese Simmental beef cattle

genomics more details view paper
  • Downloaded 743 times
  • Download rankings, all-time:
    • Site-wide: 53,304
    • In genomics: 3,706
  • Year to date:
    • Site-wide: 160,213
  • Since beginning of last month:
    • Site-wide: 182,382

Genome structure and evolution of Antirrhnum majus L.

genomics more details view paper
  • Downloaded 695 times
  • Download rankings, all-time:
    • Site-wide: 58,579
    • In genomics: 4,047
  • Year to date:
    • Site-wide: 90,347
  • Since beginning of last month:
    • Site-wide: 162,545

Digital polymerase chain reaction in an array of microfluidic printed droplets

molecular biology more details view paper
  • Downloaded 684 times
  • Download rankings, all-time:
    • Site-wide: 59,868
    • In molecular biology: 1,724
  • Year to date:
    • Site-wide: 59,705
  • Since beginning of last month:
    • Site-wide: 32,456

Incidence and Characteristics of Co-infection and Secondary Infection in Patients with COVID-19

microbiology more details view paper
  • Downloaded 647 times
  • Download rankings, all-time:
    • Site-wide: 64,498
    • In microbiology: 4,820
  • Year to date:
    • Site-wide: 35,983
  • Since beginning of last month:
    • Site-wide: 4,415

Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and disease.

genetic and genomic medicine more details view paper
  • Downloaded 589 times
  • Download rankings, all-time:
    • Site-wide: 72,924
    • In genetic and genomic medicine: 473
  • Year to date:
    • Site-wide: 18,906
  • Since beginning of last month:
    • Site-wide: 28,503

Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor

biophysics more details view paper
  • Downloaded 584 times
  • Download rankings, all-time:
    • Site-wide: 73,640
    • In biophysics: 2,635
  • Year to date:
    • Site-wide: 68,879
  • Since beginning of last month:
    • Site-wide: 74,165

Sulfated RaxX, which represents an unclassified group of ribosomally synthesized post-translationally modified peptides, binds a host immune receptor

microbiology more details view paper
  • Downloaded 579 times
  • Download rankings, all-time:
    • Site-wide: 74,486
    • In microbiology: 4,309
  • Year to date:
    • Site-wide: 172,717
  • Since beginning of last month:
    • Site-wide: 97,864

The metabolic response of Pseudomonas taiwanensis to NADH dehydrogenase deficiency

physiology more details view paper
  • Downloaded 570 times
  • Download rankings, all-time:
    • Site-wide: 75,943
    • In physiology: 455
  • Year to date:
    • Site-wide: 105,680
  • Since beginning of last month:
    • Site-wide: 117,384

Host engineering for improved valerolactam production in Pseudomonas putida

synthetic biology more details view paper
  • Downloaded 566 times
  • Download rankings, all-time:
    • Site-wide: 76,694
    • In synthetic biology: 845
  • Year to date:
    • Site-wide: 160,169
  • Since beginning of last month:
    • Site-wide: 111,719

Structural mechanism of regioselectivity in an unusual bacterial acyl-CoA dehydrogenase

biochemistry more details view paper
  • Downloaded 541 times
  • Download rankings, all-time:
    • Site-wide: 80,934
    • In biochemistry: 2,197
  • Year to date:
    • Site-wide: 91,869
  • Since beginning of last month:
    • Site-wide: 70,234

Single-cell transcriptomics reveal cell type-specific molecular changes and altered intercellular communications in chronic obstructive pulmonary disease

pathology more details view paper
  • Downloaded 526 times
  • Download rankings, all-time:
    • Site-wide: 83,759
    • In pathology: 428
  • Year to date:
    • Site-wide: 48,990
  • Since beginning of last month:
    • Site-wide: 34,550

A unified neurocognitive model of the anterior temporal lobe contributions to semantics, language, social behaviour & face recognition

neuroscience more details view paper
  • Downloaded 500 times
  • Download rankings, all-time:
    • Site-wide: 88,892
    • In neuroscience: 11,915
  • Year to date:
    • Site-wide: 184,332
  • Since beginning of last month:
    • Site-wide: 183,413

Methyl ketone production by Pseudomonas putida is enhanced by plant-derived amino acids

bioengineering more details view paper
  • Downloaded 472 times
  • Download rankings, all-time:
    • Site-wide: 94,631
    • In bioengineering: 1,768
  • Year to date:
    • Site-wide: 126,581
  • Since beginning of last month:
    • Site-wide: 49,025

IL-18 and Lower Risk for Lung Cancer: Triangulated Evidence from Germline Predictions, Pre-Diagnostic Measurements, and Tumor Expression

genetic and genomic medicine more details view paper
  • Downloaded 461 times
  • Download rankings, all-time:
    • Site-wide: 97,114
    • In genetic and genomic medicine: 693
  • Year to date:
    • Site-wide: 36,933
  • Since beginning of last month:
    • Site-wide: 8,240

Allosteric priming of E. coli CheY by the flagellar motor protein FliM

biophysics more details view paper
  • Downloaded 457 times
  • Download rankings, all-time:
    • Site-wide: 98,136
    • In biophysics: 3,348
  • Year to date:
    • Site-wide: 159,318
  • Since beginning of last month:
    • Site-wide: 128,243

The response of Pseudomonas putida to a complex lignolysate

microbiology more details view paper
  • Downloaded 437 times
  • Download rankings, all-time:
    • Site-wide: 102,778
    • In microbiology: 6,703
  • Year to date:
    • Site-wide: 94,778
  • Since beginning of last month:
    • Site-wide: 181,223

B Cell Receptor-Responsive miR-141 and viral miR-BART9 promote Epstein-Barr Virus Reactivation Through FOXO3 Inhibition

molecular biology more details view paper
  • Downloaded 374 times
  • Download rankings, all-time:
    • Site-wide: 118,621
    • In molecular biology: 3,216
  • Year to date:
    • Site-wide: 183,794
  • Since beginning of last month:
    • Site-wide: 174,027

Structure and mechanism of a mitochondrial AAA+ disaggregase CLBP

molecular biology more details view paper
  • Downloaded 322 times
  • Download rankings, all-time:
    • Site-wide: 133,406
    • In molecular biology: None
  • Year to date:
    • Site-wide: 10,633
  • Since beginning of last month:
    • Site-wide: 42,636

Blood flow coordinates collective endothelial cell migration during vascular plexus formation and promotes angiogenic sprout regression via vegfr3/flt4

developmental biology more details view paper
  • Downloaded 296 times
  • Download rankings, all-time:
    • Site-wide: 140,901
    • In developmental biology: 3,625
  • Year to date:
    • Site-wide: 105,310
  • Since beginning of last month:
    • Site-wide: 99,912

Transcription factor determines the sources of extracellular vesicle DNA

cell biology more details view paper
  • Downloaded 295 times
  • Download rankings, all-time:
    • Site-wide: 141,477
    • In cell biology: 6,765
  • Year to date:
    • Site-wide: 12,099
  • Since beginning of last month:
    • Site-wide: 71,303

Verification of SARS-CoV-2-Encoded small RNAs and contribution to Infection-Associated lung inflammation

microbiology more details view paper
  • Downloaded 290 times
  • Download rankings, all-time:
    • Site-wide: 142,786
    • In microbiology: 10,024
  • Year to date:
    • Site-wide: 97,675
  • Since beginning of last month:
    • Site-wide: 136,627

Pulmonary B cells ameliorate Alzheimer's disease-like neuropathology

neuroscience more details view paper
  • Downloaded 281 times
  • Download rankings, all-time:
    • Site-wide: 145,461
    • In neuroscience: 21,253
  • Year to date:
    • Site-wide: 94,056
  • Since beginning of last month:
    • Site-wide: 105,247

LncRNA SNHG1 suppresses LPS-induced acute lung injury by regulating miR-421/TIMP3 axis

immunology more details view paper
  • Downloaded 270 times
  • Download rankings, all-time:
    • Site-wide: 148,923
    • In immunology: 4,571
  • Year to date:
    • Site-wide: 80,943
  • Since beginning of last month:
    • Site-wide: 17,732

Environment-wide association study (EWAS) on cardiometabolic traits: A systematic assessment of the association of lifestyle variables on a longitudinal setting

epidemiology more details view paper
  • Downloaded 259 times
  • Download rankings, all-time:
    • Site-wide: 152,049
    • In epidemiology: 6,594
  • Year to date:
    • Site-wide: 58,589
  • Since beginning of last month:
    • Site-wide: 12,600

Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages

immunology more details view paper
  • Downloaded 240 times
  • Download rankings, all-time:
    • Site-wide: 157,512
    • In immunology: 4,634
  • Year to date:
    • Site-wide: 84,144
  • Since beginning of last month:
    • Site-wide: 53,896

Multiple viral microRNAs regulate interferon release and signaling early during infection with Epstein-Barr virus

microbiology more details view paper
  • Downloaded 231 times
  • Download rankings, all-time:
    • Site-wide: 160,092
    • In microbiology: 10,963
  • Year to date:
    • Site-wide: 175,220
  • Since beginning of last month:
    • Site-wide: 189,528

Uncertainty quantification in cerebral circulation simulations focusing on the collateral flow: Surrogate model approach with machine learning

bioengineering more details view paper
  • Downloaded 220 times
  • Download rankings, all-time:
    • Site-wide: 163,049
    • In bioengineering: None
  • Year to date:
    • Site-wide: 18,852
  • Since beginning of last month:
    • Site-wide: 19,547

Prohibitin protects against cigarette smoke extract-induced cell apoptosis in cultured human pulmonary microvascular endothelial cells

pharmacology and toxicology more details view paper
  • Downloaded 192 times
  • Download rankings, all-time:
    • Site-wide: 170,022
    • In pharmacology and toxicology: 1,343
  • Year to date:
    • Site-wide: 129,521
  • Since beginning of last month:
    • Site-wide: 149,887

Circulating proteins reveal prior use of menopausal hormonal therapy and increased risk of breast cancer

systems biology more details view paper
  • Downloaded 184 times
  • Download rankings, all-time:
    • Site-wide: 171,959
    • In systems biology: 3,272
  • Year to date:
    • Site-wide: 146,088
  • Since beginning of last month:
    • Site-wide: 94,137

Genetic Analysis of Bphse: a Novel Gene Complementing Resistance to Bordetella pertussis-Induced Histamine Sensitization

genetics more details view paper
  • Downloaded 139 times
  • Download rankings, all-time:
    • Site-wide: 181,237
    • In genetics: 6,383
  • Year to date:
    • Site-wide: 102,303
  • Since beginning of last month:
    • Site-wide: 75,249

Genetic Encoding of A Nonhydrolyzable Phosphotyrosine Analog in Mammalian Cells

bioengineering more details view paper
  • Downloaded 138 times
  • Download rankings, all-time:
    • Site-wide: 181,302
    • In bioengineering: 3,706
  • Year to date:
    • Site-wide: 69,003
  • Since beginning of last month:
    • Site-wide: 82,166

Serum Amyloid A promotes Acetaminophen-induced liverinjury by damaging sinusoidal endothelial cell and exacerbating platelet aggregation in liver

pharmacology and toxicology more details view paper
  • Downloaded 129 times
  • Download rankings, all-time:
    • Site-wide: 182,758
    • In pharmacology and toxicology: 1,517
  • Year to date:
    • Site-wide: 74,075
  • Since beginning of last month:
    • Site-wide: 93,080

Sex-specific effects of aging on the humoral immune response to repeat vaccination with the high-dose seasonal influenza vaccine in older adults

infectious diseases more details view paper
  • Downloaded 128 times
  • Download rankings, all-time:
    • Site-wide: 183,021
    • In infectious diseases: 7,206
  • Year to date:
    • Site-wide: 121,124
  • Since beginning of last month:
    • Site-wide: 120,201

Estimating the burden of foodborne gastroenteritis due to nontyphoidal Salmonella enterica, Shigella and Vibrio parahaemolyticus in China

epidemiology more details view paper
  • Downloaded 109 times
  • Download rankings, all-time:
    • Site-wide: 185,654
    • In epidemiology: None
  • Year to date:
    • Site-wide: 47,204
  • Since beginning of last month:
    • Site-wide: 71,375

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