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Author: Michael C O'Donovan

Rankings

  • All-time downloads: 70,585 (rank: 3,389 (tie) )
  • Categories:
    • genetic and genomic medicine: 14,990 (rank: 40 )
    • genetics: 24,475 (rank: 457 )
    • genomics: 20,523 (rank: 800 )
    • neuroscience: 2,074 (rank: 17,432 (tie) )
    • pharmacology and therapeutics: 679 (rank: 750 (tie) )
    • psychiatry and clinical psychology: 5,133 (rank: 166 )

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Preprints

Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia

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Genomewide association study identifies 30 loci associated with bipolar disorder

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    • In genetics: 42
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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
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Genetic Identification Of Brain Cell Types Underlying Schizophrenia

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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
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Psychiatric Genomics: An Update and an Agenda

genetics more details view paper
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Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

genetics more details view paper
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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
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Sex differences in gene expression in the human fetal brain

genomics more details view paper
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Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia

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    • In genetic and genomic medicine: 105
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
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A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

genetics more details view paper
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    • In genetics: 791
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Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders

genetics more details view paper
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    • In genetics: 934
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Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

genetics more details view paper
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    • In genetics: 1,512
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Genetic association study of psychotic experiences in UK Biobank

genetics more details view paper
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    • In genetics: 1,645
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Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study

genetic and genomic medicine more details view paper
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    • In genetic and genomic medicine: 248
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Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

genomics more details view paper
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    • In genomics: 3,379
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Rare schizophrenia risk variant burden is conserved in diverse human populations

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    • In genetic and genomic medicine: 315
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Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

genetics more details view paper
  • Downloaded 888 times
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    • In genetics: 1,848
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The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

genetics more details view paper
  • Downloaded 866 times
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    • In genetics: 1,847
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The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.

genetics more details view paper
  • Downloaded 823 times
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    • Site-wide: 51,617
    • In genetics: 2,184
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Clozapine metabolism is associated with Absolute Neutrophil Count in individuals with treatment-resistant schizophrenia

pharmacology and therapeutics more details view paper
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    • In pharmacology and therapeutics: 85
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Meta-analysis of Scandinavian Schizophrenia Exomes

genetics more details view paper
  • Downloaded 752 times
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    • In genetics: 2,364
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Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

genetics more details view paper
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    • In genetics: 2,422
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A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

genetics more details view paper
  • Downloaded 720 times
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    • In genetics: 2,376
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Genetic association of FMRP targets with psychiatric disorders

neuroscience more details view paper
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    • In neuroscience: 10,245
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Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls

psychiatry and clinical psychology more details view paper
  • Downloaded 613 times
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    • In psychiatry and clinical psychology: 342
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The role of rare copy number variants in depression

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    • In neuroscience: 11,519
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Dynamic expression of risk genes for schizophrenia and bipolar disorder across development

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    • In neuroscience: 11,331
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Characterization of Age and Polarity at Onset in Bipolar Disorder

psychiatry and clinical psychology more details view paper
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    • Site-wide: 85,458
    • In psychiatry and clinical psychology: 398
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Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

genetics more details view paper
  • Downloaded 545 times
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    • In genetics: 3,414
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Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder

genetic and genomic medicine more details view paper
  • Downloaded 543 times
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    • In genetic and genomic medicine: 557
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Pharmacokinetics and pharmacogenomics of clozapine in an ancestrally diverse sample: A longitudinal analysis and GWAS using clinical monitoring data from the UK

pharmacology and therapeutics more details view paper
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    • Site-wide: 99,802
    • In pharmacology and therapeutics: None
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Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

genomics more details view paper
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    • In genomics: 6,038
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Identifying novel subtypes of irritability using a developmental genetic approach

genetics more details view paper
  • Downloaded 478 times
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    • In genetics: 3,980
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Effects of pathogenic CNVs on biochemical markers: a study on the UK Biobank

genomics more details view paper
  • Downloaded 469 times
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    • Site-wide: 107,094
    • In genomics: 6,240
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Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

genomics more details view paper
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    • Site-wide: 109,914
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The rate of de novo CNVs in healthy controls

genomics more details view paper
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Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

psychiatry and clinical psychology more details view paper
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Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

neuroscience more details view paper
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Pathogenic mis-splicing of CPEB4 in schizophrenia

neuroscience more details view paper
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