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Author: Michael C O'Donovan

  • ORCiD: http://orcid.org/0000-0001-7073-2379
  • Most recently observed institution: Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences

Rankings

  • All-time downloads: 54,990 (rank: 2,995 )
  • Categories:
    • genetic and genomic medicine: 7,812 (rank: 117 )
    • genetics: 22,056 (rank: 434 )
    • genomics: 19,250 (rank: 712 )
    • neuroscience: 1,802 (rank: 14,184 (tie) )
    • pharmacology and therapeutics: 322 (rank: 783 (tie) )
    • psychiatry and clinical psychology: 3,748 (rank: 154 )

Downloads per author, site-wide

Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
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    • Site-wide: 1,380
    • In genetics: 41
  • Year to date:
    • Site-wide: 24,357
  • Since beginning of last month:
    • Site-wide: 38,465

Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 6,129 times
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    • Site-wide: 1,782
    • In genetic and genomic medicine: 8
  • Year to date:
    • Site-wide: 668
  • Since beginning of last month:
    • Site-wide: 2,676

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
  • Downloaded 4,896 times
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    • Site-wide: 2,436
    • In genomics: 237
  • Year to date:
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    • Site-wide: 65,174

Genetic Identification Of Brain Cell Types Underlying Schizophrenia

genomics more details view paper
  • Downloaded 3,628 times
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    • Site-wide: 3,708
    • In genomics: 386
  • Year to date:
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Psychiatric Genomics: An Update and an Agenda

genetics more details view paper
  • Downloaded 3,419 times
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    • Site-wide: 4,005
    • In genetics: 147
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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
  • Downloaded 2,857 times
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    • Site-wide: 5,170
    • In psychiatry and clinical psychology: 20
  • Year to date:
    • Site-wide: 1,660
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    • Site-wide: 33,980

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

genomics more details view paper
  • Downloaded 2,590 times
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    • Site-wide: 5,963
    • In genomics: 623
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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
  • Downloaded 2,542 times
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    • In genomics: 646
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Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

genetics more details view paper
  • Downloaded 2,478 times
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    • In genetics: 278
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Sex differences in gene expression in the human fetal brain

genomics more details view paper
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    • In genomics: 986
  • Year to date:
    • Site-wide: 22,638
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    • Site-wide: 82,078

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,477 times
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    • Site-wide: 13,653
    • In genomics: 1,395
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    • Site-wide: 105,822
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    • Site-wide: 72,381

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

genetics more details view paper
  • Downloaded 1,432 times
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    • Site-wide: 14,320
    • In genetics: 658
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    • Site-wide: 86,987
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Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders

genetics more details view paper
  • Downloaded 880 times
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    • Site-wide: 29,305
    • In genetics: 1,336
  • Year to date:
    • Site-wide: 14,886
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    • Site-wide: 93,846

Genetic association study of psychotic experiences in UK Biobank

genetics more details view paper
  • Downloaded 825 times
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    • Site-wide: 32,073
    • In genetics: 1,479
  • Year to date:
    • Site-wide: 81,774
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    • Site-wide: None

Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

genetics more details view paper
  • Downloaded 804 times
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    • Site-wide: 33,272
    • In genetics: 1,530
  • Year to date:
    • Site-wide: 78,315
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    • Site-wide: 72,949

The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

genetics more details view paper
  • Downloaded 796 times
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    • Site-wide: 33,714
    • In genetics: 1,546
  • Year to date:
    • Site-wide: 124,547
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Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

genetics more details view paper
  • Downloaded 785 times
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    • Site-wide: 34,409
    • In genetics: 1,563
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    • Site-wide: 84,420
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    • Site-wide: 72,992

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

genomics more details view paper
  • Downloaded 741 times
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    • Site-wide: 37,255
    • In genomics: 3,107
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    • Site-wide: 37,844
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Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study

genetic and genomic medicine more details view paper
  • Downloaded 702 times
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    • Site-wide: 40,055
    • In genetic and genomic medicine: 155
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    • Site-wide: 29,355
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    • Site-wide: 32,663

Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 661 times
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    • Site-wide: 43,369
    • In genetic and genomic medicine: 171
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    • Site-wide: 5,693
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    • Site-wide: 16,602

A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

genetics more details view paper
  • Downloaded 657 times
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    • Site-wide: 43,792
    • In genetics: 1,959
  • Year to date:
    • Site-wide: 114,986
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    • Site-wide: 64,295

Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

genetics more details view paper
  • Downloaded 602 times
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    • In genetics: 2,167
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    • Site-wide: 40,320
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The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.

genetics more details view paper
  • Downloaded 598 times
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    • Site-wide: 49,258
    • In genetics: 2,183
  • Year to date:
    • Site-wide: 55,682
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    • Site-wide: 62,390

Genetic association of FMRP targets with psychiatric disorders

neuroscience more details view paper
  • Downloaded 575 times
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    • Site-wide: 51,836
    • In neuroscience: 7,446
  • Year to date:
    • Site-wide: 75,226
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Dynamic expression of risk genes for schizophrenia and bipolar disorder across development

neuroscience more details view paper
  • Downloaded 506 times
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    • Site-wide: 60,298
    • In neuroscience: 8,862
  • Year to date:
    • Site-wide: 130,903
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    • Site-wide: 40,445

Meta-analysis of Scandinavian Schizophrenia Exomes

genetics more details view paper
  • Downloaded 492 times
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    • Site-wide: 62,157
    • In genetics: 2,755
  • Year to date:
    • Site-wide: 72,174
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    • Site-wide: 91,585

The role of rare copy number variants in depression

neuroscience more details view paper
  • Downloaded 484 times
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    • Site-wide: 63,229
    • In neuroscience: 9,311
  • Year to date:
    • Site-wide: 100,359
  • Since beginning of last month:
    • Site-wide: 42,269

Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls

psychiatry and clinical psychology more details view paper
  • Downloaded 475 times
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    • Site-wide: 64,667
    • In psychiatry and clinical psychology: 230
  • Year to date:
    • Site-wide: 58,778
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Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

genetics more details view paper
  • Downloaded 472 times
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    • Site-wide: 65,071
    • In genetics: 2,867
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    • Site-wide: 104,034
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Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

genomics more details view paper
  • Downloaded 406 times
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    • Site-wide: 75,898
    • In genomics: 5,104
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    • Site-wide: 148,481
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    • Site-wide: 82,115

Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

genomics more details view paper
  • Downloaded 399 times
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    • Site-wide: 77,202
    • In genomics: 5,163
  • Year to date:
    • Site-wide: 104,063
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Identifying novel subtypes of irritability using a developmental genetic approach

genetics more details view paper
  • Downloaded 390 times
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    • Site-wide: 78,892
    • In genetics: 3,437
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    • Site-wide: 130,029
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    • Site-wide: 81,109

The rate of de novo CNVs in healthy controls

genomics more details view paper
  • Downloaded 367 times
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    • Site-wide: 83,223
    • In genomics: 5,422
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    • Site-wide: 112,618
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    • Site-wide: 92,337

Effects of pathogenic CNVs on biochemical markers: a study on the UK Biobank

genomics more details view paper
  • Downloaded 329 times
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    • Site-wide: 91,082
    • In genomics: 5,710
  • Year to date:
    • Site-wide: 95,268
  • Since beginning of last month:
    • Site-wide: 42,699

Clozapine metabolism is associated with Absolute Neutrophil Count in individuals with treatment-resistant schizophrenia

pharmacology and therapeutics more details view paper
  • Downloaded 322 times
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    • Site-wide: 92,634
    • In pharmacology and therapeutics: 97
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    • Site-wide: 16,065
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    • Site-wide: 111,975

Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder

genetic and genomic medicine more details view paper
  • Downloaded 320 times
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    • Site-wide: 93,230
    • In genetic and genomic medicine: 415
  • Year to date:
    • Site-wide: 43,389
  • Since beginning of last month:
    • Site-wide: 34,186

Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

neuroscience more details view paper
  • Downloaded 237 times
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    • Site-wide: 112,581
    • In neuroscience: 17,275
  • Year to date:
    • Site-wide: 94,412
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Characterization of Age and Polarity at Onset in Bipolar Disorder

psychiatry and clinical psychology more details view paper
  • Downloaded 229 times
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    • Site-wide: 114,703
    • In psychiatry and clinical psychology: 498
  • Year to date:
    • Site-wide: 25,467
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    • Site-wide: 103,177

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

psychiatry and clinical psychology more details view paper
  • Downloaded 187 times
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    • Site-wide: 125,053
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