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Author: Benjamin Werner

Rankings

  • All-time downloads: 23,549 (rank: 11,425 )
  • Categories:
    • bioinformatics: 5,292 (rank: 2,881 (tie) )
    • cancer biology: 14,442 (rank: 154 )
    • evolutionary biology: 613 (rank: 14,836 (tie) )
    • genetics: 805 (rank: 22,284 (tie) )
    • genomics: 980 (rank: 27,786 (tie) )

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Preprints

Model-based tumor subclonal reconstruction

bioinformatics more details view paper
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    • Site-wide: 5,439
    • In bioinformatics: 468
  • Year to date:
    • Site-wide: 74,145
  • Since beginning of last month:
    • Site-wide: 72,578

Quantification of subclonal selection in cancer from bulk sequencing data

cancer biology more details view paper
  • Downloaded 3,079 times
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    • Site-wide: 6,071
    • In cancer biology: 81
  • Year to date:
    • Site-wide: 82,515
  • Since beginning of last month:
    • Site-wide: 81,791

Evolutionary dynamics of neoantigens in growing tumours

cancer biology more details view paper
  • Downloaded 2,854 times
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    • Site-wide: 6,767
    • In cancer biology: 93
  • Year to date:
    • Site-wide: 88,621
  • Since beginning of last month:
    • Site-wide: 167,673

Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers

cancer biology more details view paper
  • Downloaded 2,163 times
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    • Site-wide: 10,126
    • In cancer biology: 245
  • Year to date:
    • Site-wide: 2,446
  • Since beginning of last month:
    • Site-wide: 1,401

Measuring single cell divisions in human cancers from multi-region sequencing data

cancer biology more details view paper
  • Downloaded 1,693 times
  • Download rankings, all-time:
    • Site-wide: 14,600
    • In cancer biology: 299
  • Year to date:
    • Site-wide: 51,208
  • Since beginning of last month:
    • Site-wide: 41,002

Stochastic dynamics of extra-chromosomal DNA

cancer biology more details view paper
  • Downloaded 1,242 times
  • Download rankings, all-time:
    • Site-wide: 23,452
    • In cancer biology: 550
  • Year to date:
    • Site-wide: 53,001
  • Since beginning of last month:
    • Site-wide: 59,668

Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

bioinformatics more details view paper
  • Downloaded 1,097 times
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    • Site-wide: 28,375
    • In bioinformatics: 2,983
  • Year to date:
    • Site-wide: 120,516
  • Since beginning of last month:
    • Site-wide: 156,084

Reply: Neutral tumor evolution?

cancer biology more details view paper
  • Downloaded 1,068 times
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    • Site-wide: 29,536
    • In cancer biology: 714
  • Year to date:
    • Site-wide: 135,407
  • Since beginning of last month:
    • Site-wide: 94,555

dN/dS dynamics quantify tumour immunogenicity and predict response to immunotherapy

genomics more details view paper
  • Downloaded 1,057 times
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    • Site-wide: 30,000
    • In genomics: 2,671
  • Year to date:
    • Site-wide: 18,129
  • Since beginning of last month:
    • Site-wide: 10,388

Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data

cancer biology more details view paper
  • Downloaded 1,003 times
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    • Site-wide: 32,375
    • In cancer biology: 928
  • Year to date:
    • Site-wide: 19,231
  • Since beginning of last month:
    • Site-wide: 13,093

Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

bioinformatics more details view paper
  • Downloaded 904 times
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    • Site-wide: 37,763
    • In bioinformatics: 3,862
  • Year to date:
    • Site-wide: 110,871
  • Since beginning of last month:
    • Site-wide: 176,548

Mutational landscapes of normal breast during age and pregnancy determine cancer risk

genetics more details view paper
  • Downloaded 848 times
  • Download rankings, all-time:
    • Site-wide: 41,438
    • In genetics: 1,773
  • Year to date:
    • Site-wide: 42,682
  • Since beginning of last month:
    • Site-wide: 23,269

Estimating stem cell fractions in hierarchically organized tumors

cancer biology more details view paper
  • Downloaded 774 times
  • Download rankings, all-time:
    • Site-wide: 47,329
    • In cancer biology: 1,244
  • Year to date:
    • Site-wide: 180,122
  • Since beginning of last month:
    • Site-wide: 169,474

Mutation Rate Evolution Drives Immune Escape In Mismatch Repair-Deficient Cancer

cancer biology more details view paper
  • Downloaded 690 times
  • Download rankings, all-time:
    • Site-wide: 55,557
    • In cancer biology: None
  • Year to date:
    • Site-wide: 2,067
  • Since beginning of last month:
    • Site-wide: 1,773

Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates

cancer biology more details view paper
  • Downloaded 474 times
  • Download rankings, all-time:
    • Site-wide: 88,384
    • In cancer biology: 2,497
  • Year to date:
    • Site-wide: 145,469
  • Since beginning of last month:
    • Site-wide: None

How many samples are needed to infer truly clonal mutations from heterogenous tumours?

cancer biology more details view paper
  • Downloaded 383 times
  • Download rankings, all-time:
    • Site-wide: 109,080
    • In cancer biology: 3,157
  • Year to date:
    • Site-wide: 174,831
  • Since beginning of last month:
    • Site-wide: 169,608

Should tissue structure suppress or amplify selection to minimize cancer risk?

evolutionary biology more details view paper
  • Downloaded 318 times
  • Download rankings, all-time:
    • Site-wide: 126,801
    • In evolutionary biology: 5,868
  • Year to date:
    • Site-wide: 176,154
  • Since beginning of last month:
    • Site-wide: 153,195

Replicative cellular age distributions in compartmentalised tissues

evolutionary biology more details view paper
  • Downloaded 303 times
  • Download rankings, all-time:
    • Site-wide: 131,095
    • In evolutionary biology: 6,019
  • Year to date:
    • Site-wide: 162,634
  • Since beginning of last month:
    • Site-wide: 168,887

Quantification of spatial subclonal interactions enhancing the invasive phenotype of paediatric glioma

cancer biology more details view paper
  • Downloaded 272 times
  • Download rankings, all-time:
    • Site-wide: 140,072
    • In cancer biology: 4,224
  • Year to date:
    • Site-wide: 63,872
  • Since beginning of last month:
    • Site-wide: 80,845

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