Author: Nick Patterson

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Preprints

The Genomic Formation of South and Central Asia

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Massive migration from the steppe is a source for Indo-European languages in Europe

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Eight thousand years of natural selection in Europe

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The genetic structure of the world's first farmers

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The Genomic History Of Southeastern Europe

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Ancient human genomes suggest three ancestral populations for present-day Europeans

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  • Site-wide: 396
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The Beaker Phenomenon And The Genomic Transformation Of Northwest Europe

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An Atlas of Genetic Correlations across Human Diseases and Traits

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  • Site-wide: 565
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  • Site-wide: 13,779
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Paleolithic DNA from the Caucasus reveals core of West Eurasian ancestry

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Partitioning heritability by functional category using GWAS summary statistics

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LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies

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Reconstructing Austronesian population history in Island Southeast Asia

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The Arrival of Steppe and Iranian Related Ancestry in the Islands of the Western Mediterranean

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The promise of disease gene discovery in South Asia

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  • Site-wide: 3,879
  • In evolutionary biology: 67
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  • Site-wide: 60,138

Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

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  • Site-wide: 4,418
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Signals of polygenic adaptation on height have been overestimated due to uncorrected population structure in genome-wide association studies

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  • Site-wide: 4,906
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Genomic architecture and introgression shape a butterfly radiation

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  • Site-wide: 5,054
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Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

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  • Site-wide: 5,890
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  • Site-wide: 73,064

A unified genealogy of modern and ancient genomes

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  • Site-wide: 6,712
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Efficient Bayesian mixed model analysis increases association power in large cohorts

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  • Site-wide: 7,100
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  • Site-wide: 91,654
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No evidence for unknown archaic ancestry in South Asia

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  • Site-wide: 8,198
  • In genomics: 852
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  • Site-wide: 140,642
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Polygenicity of complex traits is explained by negative selection

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  • Site-wide: 9,047
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• Year to date:
  • Site-wide: 91,151
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  • Site-wide: 38,260

Assessing the Performance of qpAdm: A Statistical Tool for Studying Population Admixture

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  • Site-wide: 33,449

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

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  • Site-wide: 11,922
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Social stratification without genetic differentiation at the site of Kulubnarti in Christian Period Nubia

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  • Site-wide: 12,582
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Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

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  • Site-wide: 14,321
  • In genetics: 659
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  • Site-wide: 131,874
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Combining case-control status and family history of disease increases association power

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  • Site-wide: 17,500
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No statistical evidence for an effect of CCR5-∆32 on lifespan in the UK Biobank cohort

• Downloaded 1,236 times
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  • Site-wide: 17,870
  • In genetics: 830
• Year to date:
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  • Site-wide: 90,087

Subtle stratification confounds estimates of heritability from rare variants

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  • Site-wide: 18,734
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  • Site-wide: 68,592

Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

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  • Site-wide: 18,971
  • In genetics: 882
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  • Site-wide: 112,297
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  • Site-wide: None

miqoGraph : Fitting admixture graphs using mixed-integer quadratic optimization

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  • Site-wide: 19,692
  • In genomics: 1,911
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  • Site-wide: 37,360

Dating ancient human samples using the recombination clock

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  • Site-wide: 23,000
  • In evolutionary biology: 938
• Year to date:
  • Site-wide: 102,882
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  • Site-wide: None

Quantification of genetic components of population differentiation in UK Biobank traits reveals signals of polygenic selection

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  • Site-wide: 23,980
  • In genetics: 1,106
• Year to date:
  • Site-wide: 110,314
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  • Site-wide: 72,986

ContamLD: Estimation of Ancient Nuclear DNA Contamination Using Breakdown of Linkage Disequilibrium

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  • Site-wide: 44,088
  • In evolutionary biology: 2,133
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  • Site-wide: 94,758

Negative short-range genomic autocorrelation of causal effects on human complex traits

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  • Site-wide: 44,683
  • In genetics: 1,995
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  • Site-wide: 52,335

Mixed Model Association with Family-Biased Case-Control Ascertainment

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  • Site-wide: 60,776
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• Year to date:
  • Site-wide: 148,754
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  • Site-wide: 73,420

Combining Ancient DNA and Radiocarbon Dating Data to Increase Chronological Precision

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  • In genomics: 4,618
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