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Author: Nevan J Krogan

Rankings

  • All-time downloads: 295,556 (rank: 151 )
  • Categories:
    • biochemistry: 21,124 (rank: 83 )
    • bioinformatics: 2,378 (rank: 7,703 (tie) )
    • biophysics: 2,951 (rank: 1,658 (tie) )
    • cancer biology: 2,073 (rank: 4,117 (tie) )
    • cell biology: 4,567 (rank: 1,222 (tie) )
    • developmental biology: 1,335 (rank: 3,816 (tie) )
    • evolutionary biology: 661 (rank: 13,310 (tie) )
    • genetics: 4,780 (rank: 4,373 )
    • immunology: 90 (rank: 44,228 (tie) )
    • infectious diseases: 46,590 (rank: 1,455 )
    • microbiology: 20,299 (rank: 1,044 )
    • molecular biology: 2,400 (rank: 2,452 (tie) )
    • neuroscience: 1,007 (rank: 31,135 (tie) )
    • pharmacology and toxicology: 1,996 (rank: 649 (tie) )
    • physiology: 530 (rank: 4,175 (tie) )
    • systems biology: 182,775 (rank: 2 )

Downloads per author, site-wide

Preprints

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

microbiology more details view paper

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A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

systems biology more details view paper
  • Downloaded 178,503 times
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    • Site-wide: 31
    • In systems biology: 1
  • Year to date:
    • Site-wide: 2,129
  • Since beginning of last month:
    • Site-wide: 1,098

Test performance evaluation of SARS-CoV-2 serological assays

infectious diseases more details view paper
  • Downloaded 41,781 times
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    • Site-wide: 210
    • In infectious diseases: 82
  • Year to date:
    • Site-wide: 1,636
  • Since beginning of last month:
    • Site-wide: 1,620

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

biochemistry more details view paper
  • Downloaded 20,073 times
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    • Site-wide: 492
    • In biochemistry: 3
  • Year to date:
    • Site-wide: 3,588
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    • Site-wide: 2,385

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

microbiology more details view paper
  • Downloaded 6,678 times
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    • Site-wide: 1,918
    • In microbiology: 157
  • Year to date:
    • Site-wide: 1,773
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    • Site-wide: 1,471

Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.

infectious diseases more details view paper
  • Downloaded 4,809 times
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    • Site-wide: 3,007
    • In infectious diseases: 739
  • Year to date:
    • Site-wide: 507
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Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses

microbiology more details view paper
  • Downloaded 3,001 times
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    • Site-wide: 5,790
    • In microbiology: 364
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CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

biophysics more details view paper
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    • Site-wide: 5,940
    • In biophysics: 94
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Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

microbiology more details view paper
  • Downloaded 2,872 times
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    • Site-wide: 6,168
    • In microbiology: 391
  • Year to date:
    • Site-wide: 10,266
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A CRISPR-Cas9 Genome Engineering Platform in Primary CD4+ T Cells for the Interrogation of HIV Host Factors

systems biology more details view paper
  • Downloaded 2,810 times
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    • Site-wide: 6,356
    • In systems biology: 94
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SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells

bioinformatics more details view paper
  • Downloaded 2,378 times
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    • Site-wide: 8,133
    • In bioinformatics: 863
  • Year to date:
    • Site-wide: 12,743
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    • Site-wide: 7,311

Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

pharmacology and toxicology more details view paper
  • Downloaded 1,996 times
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    • Site-wide: 10,504
    • In pharmacology and toxicology: 61
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    • Site-wide: 12,468

Adhesion-mediated mechanosignaling forces mitohormesis

cell biology more details view paper
  • Downloaded 1,908 times
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    • Site-wide: 11,245
    • In cell biology: 276
  • Year to date:
    • Site-wide: 57,365
  • Since beginning of last month:
    • Site-wide: 34,389

Efficient Generation of Isogenic Primary Human Myeloid Cells using CRISPR-Cas9 Ribonucleoproteins

genetics more details view paper
  • Downloaded 1,773 times
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    • Site-wide: 12,501
    • In genetics: 520
  • Year to date:
    • Site-wide: 21,006
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    • Site-wide: 41,781

Biophysical basis of cellular multi-specificity encoded in a model molecular switch

systems biology more details view paper
  • Downloaded 1,462 times
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    • Site-wide: 16,797
    • In systems biology: 292
  • Year to date:
    • Site-wide: 20,740
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    • Site-wide: 62,008

BAF chromatin remodeling complex subunit diversity promotes temporally distinct gene expression programs in cardiogenes

developmental biology more details view paper
  • Downloaded 1,335 times
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    • Site-wide: 19,283
    • In developmental biology: 298
  • Year to date:
    • Site-wide: 72,143
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    • Site-wide: 78,263

Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins

molecular biology more details view paper
  • Downloaded 1,251 times
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    • Site-wide: 21,228
    • In molecular biology: 562
  • Year to date:
    • Site-wide: 39,101
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    • Site-wide: 92,432

Delineation of the SUMO-Modified Proteome Reveals Regulatory Functions Throughout Meiosis

genetics more details view paper
  • Downloaded 1,239 times
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    • Site-wide: 21,541
    • In genetics: 926
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    • Site-wide: 69,781
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Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

microbiology more details view paper
  • Downloaded 1,087 times
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    • Site-wide: 26,332
    • In microbiology: 1,525
  • Year to date:
    • Site-wide: 23,922
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    • Site-wide: 21,153

SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage

microbiology more details view paper
  • Downloaded 1,057 times
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    • Site-wide: 27,476
    • In microbiology: 1,596
  • Year to date:
    • Site-wide: 103,647
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    • Site-wide: 3,738

A tyrosine kinase protein interaction map reveals targetable EGFR network oncogenesis in lung cancer

cancer biology more details view paper
  • Downloaded 1,039 times
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    • Site-wide: 28,139
    • In cancer biology: 708
  • Year to date:
    • Site-wide: 54,949
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    • Site-wide: 17,363

Tau interactome mapping reveals dynamic processes in synapses and mitochondria associated with neurodegenerative disease

neuroscience more details view paper
  • Downloaded 1,007 times
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    • Site-wide: 29,519
    • In neuroscience: 3,693
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    • Site-wide: 2,633
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    • Site-wide: 6,721

The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein

microbiology more details view paper
  • Downloaded 989 times
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    • Site-wide: 30,316
    • In microbiology: 1,761
  • Year to date:
    • Site-wide: 141,912
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Global proteomic profiling of primary macrophages during M. tuberculosis infection identifies TAX1BP1 as a mediator of autophagy targeting

microbiology more details view paper
  • Downloaded 988 times
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    • Site-wide: 30,342
    • In microbiology: 1,763
  • Year to date:
    • Site-wide: 146,668
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    • Site-wide: 161,122

An Mtb-Human Protein-Protein Interaction Map Reveals that Bacterial LpqN Antagonizes CBL, a Host Ubiquitin Ligase that Regulates the Balance Between Anti-Viral and Anti-Bacterial Responses

microbiology more details view paper
  • Downloaded 921 times
  • Download rankings, all-time:
    • Site-wide: 33,697
    • In microbiology: 1,979
  • Year to date:
    • Site-wide: 77,227
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    • Site-wide: 156,776

Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway

cell biology more details view paper
  • Downloaded 863 times
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    • Site-wide: 36,991
    • In cell biology: 1,420
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    • Site-wide: 11,100
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    • Site-wide: 89,571

Integration of Protein Interactome Networks with Congenital Heart Disease Variants Reveals Candidate Disease Genes

genetics more details view paper
  • Downloaded 824 times
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    • Site-wide: 39,638
    • In genetics: 1,687
  • Year to date:
    • Site-wide: 63,580
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    • Site-wide: 19,402

Two accessory proteins govern MmpL3 mycolic acid transport in mycobacteria

microbiology more details view paper
  • Downloaded 769 times
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    • Site-wide: 43,760
    • In microbiology: 2,613
  • Year to date:
    • Site-wide: 28,226
  • Since beginning of last month:
    • Site-wide: 113,463

Smoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits

biochemistry more details view paper
  • Downloaded 762 times
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    • Site-wide: 44,334
    • In biochemistry: 1,116
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    • Site-wide: 58,293
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    • Site-wide: 131,294

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

molecular biology more details view paper
  • Downloaded 698 times
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    • Site-wide: 50,029
    • In molecular biology: 1,410
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    • Site-wide: 14,332
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    • Site-wide: 16,351

Synthetic essentiality of metabolic regulator PDHK1 in PTEN-deficient cells and cancers

cancer biology more details view paper
  • Downloaded 687 times
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    • Site-wide: 51,158
    • In cancer biology: 1,437
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    • Site-wide: 96,414
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    • Site-wide: 159,931

A ciliopathy complex builds distal appendages to initiate ciliogenesis

cell biology more details view paper
  • Downloaded 670 times
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    • Site-wide: 52,940
    • In cell biology: 2,248
  • Year to date:
    • Site-wide: 82,402
  • Since beginning of last month:
    • Site-wide: 16,865

Conservation and structural analysis of the Xenopus laevis phospho-proteome

evolutionary biology more details view paper
  • Downloaded 661 times
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    • Site-wide: 53,940
    • In evolutionary biology: 2,540
  • Year to date:
    • Site-wide: 79,368
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    • Site-wide: 117,261

Comparative analysis of macrophage post-translational modifications during intracellular bacterial pathogen infection

microbiology more details view paper
  • Downloaded 579 times
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    • Site-wide: 64,015
    • In microbiology: 4,002
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    • Site-wide: 32,193
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Brown adipocyte NOSEMPE promotes nonmitochondrial thermogenesis and improves systemic metabolism through ATF4 activation

physiology more details view paper
  • Downloaded 530 times
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    • Site-wide: 71,266
    • In physiology: 456
  • Year to date:
    • Site-wide: 128,046
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    • Site-wide: 149,095

Protein Moonlighting Revealed by Non-Catalytic Phenotypes of Yeast Enzymes

genetics more details view paper
  • Downloaded 476 times
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    • Site-wide: 80,590
    • In genetics: 3,349
  • Year to date:
    • Site-wide: 97,723
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    • Site-wide: 92,963

Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2

molecular biology more details view paper
  • Downloaded 451 times
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    • Site-wide: 85,450
    • In molecular biology: 2,501
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    • Site-wide: 1,347
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Chaperone-Mediated Reflux of Secretory Proteins to the Cytosol During Endoplasmic Reticulum Stress

cell biology more details view paper
  • Downloaded 443 times
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    • Site-wide: 86,959
    • In cell biology: 3,957
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Endosomal cAMP production broadly impacts the cellular phosphoproteome

cell biology more details view paper
  • Downloaded 433 times
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    • Site-wide: 88,990
    • In cell biology: 4,075
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Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function

microbiology more details view paper
  • Downloaded 428 times
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    • Site-wide: 90,139
    • In microbiology: 6,025
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    • Site-wide: 86,131
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Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the viral Core

microbiology more details view paper
  • Downloaded 423 times
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    • Site-wide: 91,096
    • In microbiology: 6,097
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    • Site-wide: 139,174
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    • Site-wide: 114,260

Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection

microbiology more details view paper
  • Downloaded 351 times
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    • Site-wide: 107,858
    • In microbiology: 7,486
  • Year to date:
    • Site-wide: 84,913
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    • Site-wide: 84,399

Oncogenic PKA signaling stabilizes MYC oncoproteins via an aurora kinase A-dependent mechanism

cancer biology more details view paper
  • Downloaded 347 times
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    • Site-wide: 108,806
    • In cancer biology: 3,274
  • Year to date:
    • Site-wide: 51,774
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    • Site-wide: 40,183

Functional analysis of a common BAG3 allele associated with protection from heart failure

genetics more details view paper
  • Downloaded 318 times
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    • Site-wide: 116,434
    • In genetics: 4,683
  • Year to date:
    • Site-wide: 30,958
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Bimodal evolution of Src and Abl kinase substrate specificity revealed using mammalian cell extract as substrate pool

biochemistry more details view paper
  • Downloaded 289 times
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    • Site-wide: 124,215
    • In biochemistry: 3,702
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    • Site-wide: 71,542
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    • Site-wide: 90,375

The CCL2 Chemokine Promotes Early Seeding of the Latent HIV Reservoir

cell biology more details view paper
  • Downloaded 250 times
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    • Site-wide: 134,719
    • In cell biology: 6,232
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    • Site-wide: 43,696
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    • Site-wide: 57,572

Hepatitis C Virus Infects and Perturbs Liver Stem Cells

microbiology more details view paper
  • Downloaded 156 times
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    • Site-wide: 157,765
    • In microbiology: 11,857
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    • Site-wide: 22,227
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The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae

genetics more details view paper
  • Downloaded 150 times
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    • Site-wide: 158,817
    • In genetics: 6,053
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    • Site-wide: 148,881
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    • Site-wide: 131,895

Type I IFN promotes pathogenic inflammatory monocyte maturation during H5N1 infection

immunology more details view paper
  • Downloaded 90 times
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    • Site-wide: 168,290
    • In immunology: 5,222
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