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Author: Bo Li

  • ORCiD: http://orcid.org/0000-0002-9078-961X
  • Most recently observed institution: Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA; Broad Institute of Harvard and MIT, Cambridge, MA

Rankings

  • All-time downloads: 77,373 (rank: 2,113 )
  • Categories:
    • biochemistry: 282 (rank: 20,118 (tie) )
    • bioinformatics: 23,555 (rank: 149 )
    • cancer biology: 7,139 (rank: 377 )
    • cell biology: 3,478 (rank: 1,501 (tie) )
    • developmental biology: 4,571 (rank: 358 )
    • genetics: 1,345 (rank: 13,541 (tie) )
    • genomics: 19,467 (rank: 700 )
    • immunology: 6,399 (rank: 1,531 )
    • microbiology: 883 (rank: 18,751 (tie) )
    • molecular biology: 329 (rank: 20,285 (tie) )
    • neuroscience: 9,324 (rank: 1,668 )
    • plant biology: 228 (rank: 17,758 (tie) )
    • systems biology: 373 (rank: 11,148 (tie) )

Downloads per author, site-wide

Preprints

KIRCLE: An Analysis of Variations in KIR Genes in The Cancer Genome Atlas and UK Biobank

bioinformatics more details view paper

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Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define colitis associated with immune checkpoint inhibitors

immunology more details view paper

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STAR-Fusion: Fast and Accurate Fusion Transcript Detection from RNA-Seq

bioinformatics more details view paper
  • Downloaded 9,163 times
  • Download rankings, all-time:
    • Site-wide: 1,086
    • In bioinformatics: 56
  • Year to date:
    • Site-wide: 2,055
  • Since beginning of last month:
    • Site-wide: 1,003

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

genomics more details view paper
  • Downloaded 7,733 times
  • Download rankings, all-time:
    • Site-wide: 1,354
    • In genomics: 107
  • Year to date:
    • Site-wide: 7,976
  • Since beginning of last month:
    • Site-wide: 9,372

Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

cancer biology more details view paper
  • Downloaded 4,593 times
  • Download rankings, all-time:
    • Site-wide: 2,720
    • In cancer biology: 34
  • Year to date:
    • Site-wide: 1,992
  • Since beginning of last month:
    • Site-wide: 1,370

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

genomics more details view paper
  • Downloaded 4,447 times
  • Download rankings, all-time:
    • Site-wide: 2,836
    • In genomics: 287
  • Year to date:
    • Site-wide: 16,258
  • Since beginning of last month:
    • Site-wide: 8,771

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

genomics more details view paper
  • Downloaded 4,172 times
  • Download rankings, all-time:
    • Site-wide: 3,112
    • In genomics: 318
  • Year to date:
    • Site-wide: 547
  • Since beginning of last month:
    • Site-wide: 39,389

Decoding the development of the blood and immune systems during human fetal liver haematopoiesis

developmental biology more details view paper
  • Downloaded 3,724 times
  • Download rankings, all-time:
    • Site-wide: 3,646
    • In developmental biology: 32
  • Year to date:
    • Site-wide: 21,732
  • Since beginning of last month:
    • Site-wide: 9,711

Single-cell transcriptome profiling of an adult human cell atlas of 15 major organs

cell biology more details view paper
  • Downloaded 3,478 times
  • Download rankings, all-time:
    • Site-wide: 3,995
    • In cell biology: 70
  • Year to date:
    • Site-wide: 8,932
  • Since beginning of last month:
    • Site-wide: 95,527

Evaluation of de novo transcriptome assemblies from RNA-Seq data

bioinformatics more details view paper
  • Downloaded 3,105 times
  • Download rankings, all-time:
    • Site-wide: 4,702
    • In bioinformatics: 452
  • Year to date:
    • Site-wide: 104,536
  • Since beginning of last month:
    • Site-wide: None

A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets

immunology more details view paper
  • Downloaded 2,474 times
  • Download rankings, all-time:
    • Site-wide: 6,536
    • In immunology: 221
  • Year to date:
    • Site-wide: 11,544
  • Since beginning of last month:
    • Site-wide: 6,093

Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration

bioinformatics more details view paper
  • Downloaded 2,287 times
  • Download rankings, all-time:
    • Site-wide: 7,343
    • In bioinformatics: 802
  • Year to date:
    • Site-wide: 116,640
  • Since beginning of last month:
    • Site-wide: 121,736

The landscape of antigen-specific T cells in human cancers

bioinformatics more details view paper
  • Downloaded 2,249 times
  • Download rankings, all-time:
    • Site-wide: 7,538
    • In bioinformatics: 839
  • Year to date:
    • Site-wide: 22,016
  • Since beginning of last month:
    • Site-wide: 14,248

Cumulus: a cloud-based data analysis framework for large-scale single-cell and single-nucleus RNA-seq

bioinformatics more details view paper
  • Downloaded 1,917 times
  • Download rankings, all-time:
    • Site-wide: 9,504
    • In bioinformatics: 1,093
  • Year to date:
    • Site-wide: 23,350
  • Since beginning of last month:
    • Site-wide: 91,720

A fluorescent sensor for spatiotemporally resolved endocannabinoid dynamics in vitro and in vivo

neuroscience more details view paper
  • Downloaded 1,859 times
  • Download rankings, all-time:
    • Site-wide: 9,932
    • In neuroscience: 1,011
  • Year to date:
    • Site-wide: 2,410
  • Since beginning of last month:
    • Site-wide: 736

The central amygdala controls learning in the lateral amygdala

neuroscience more details view paper
  • Downloaded 1,715 times
  • Download rankings, all-time:
    • Site-wide: 11,201
    • In neuroscience: 1,158
  • Year to date:
    • Site-wide: 104,878
  • Since beginning of last month:
    • Site-wide: None

Ultrasensitive detection of TCR hypervariable region in solid-tissue RNA-seq data

bioinformatics more details view paper
  • Downloaded 1,651 times
  • Download rankings, all-time:
    • Site-wide: 11,858
    • In bioinformatics: 1,364
  • Year to date:
    • Site-wide: 68,914
  • Since beginning of last month:
    • Site-wide: 31,824

Opposing contributions of GABAergic and glutamatergic ventral pallidal neurons to motivational behaviours

neuroscience more details view paper
  • Downloaded 1,504 times
  • Download rankings, all-time:
    • Site-wide: 13,544
    • In neuroscience: 1,462
  • Year to date:
    • Site-wide: 66,192
  • Since beginning of last month:
    • Site-wide: 24,708

Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology

genetics more details view paper
  • Downloaded 1,345 times
  • Download rankings, all-time:
    • Site-wide: 16,077
    • In genetics: 740
  • Year to date:
    • Site-wide: 30,584
  • Since beginning of last month:
    • Site-wide: 13,476

Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors.

immunology more details view paper
  • Downloaded 1,303 times
  • Download rankings, all-time:
    • Site-wide: 16,891
    • In immunology: 563
  • Year to date:
    • Site-wide: 25,287
  • Since beginning of last month:
    • Site-wide: 17,323

The common neoantigens in colorectal cancer are predicted and validated to be presented or immunogenic

immunology more details view paper
  • Downloaded 1,164 times
  • Download rankings, all-time:
    • Site-wide: 19,939
    • In immunology: 675
  • Year to date:
    • Site-wide: 22,518
  • Since beginning of last month:
    • Site-wide: 10,891

EPIP: MHC-I epitope prediction integrating mass spectrometry derived motifs and tissue-specific expression profiles

bioinformatics more details view paper
  • Downloaded 1,145 times
  • Download rankings, all-time:
    • Site-wide: 20,433
    • In bioinformatics: 2,338
  • Year to date:
    • Site-wide: 54,194
  • Since beginning of last month:
    • Site-wide: 111,807

Comparative analysis of sequencing technologies platforms for single-cell transcriptomics

genomics more details view paper
  • Downloaded 1,112 times
  • Download rankings, all-time:
    • Site-wide: 21,349
    • In genomics: 2,036
  • Year to date:
    • Site-wide: 99,194
  • Since beginning of last month:
    • Site-wide: 37,371

Parvalbumin interneuron dysfunction in a thalamus - prefrontal cortex circuit in Disc1 deficiency mice

neuroscience more details view paper
  • Downloaded 1,099 times
  • Download rankings, all-time:
    • Site-wide: 21,719
    • In neuroscience: 2,670
  • Year to date:
    • Site-wide: 101,110
  • Since beginning of last month:
    • Site-wide: 70,736

An insula-central amygdala circuit for behavioral inhibition

neuroscience more details view paper
  • Downloaded 1,027 times
  • Download rankings, all-time:
    • Site-wide: 23,977
    • In neuroscience: 2,952
  • Year to date:
    • Site-wide: 117,759
  • Since beginning of last month:
    • Site-wide: 118,249

Prober: A general toolkit for analyzing sequencing-based 'toeprinting' assays

genomics more details view paper
  • Downloaded 1,025 times
  • Download rankings, all-time:
    • Site-wide: 24,033
    • In genomics: 2,254
  • Year to date:
    • Site-wide: 124,386
  • Since beginning of last month:
    • Site-wide: None

RNA polymerase mapping in plants identifies enhancers enriched in causal variants

genomics more details view paper
  • Downloaded 978 times
  • Download rankings, all-time:
    • Site-wide: 25,738
    • In genomics: 2,380
  • Year to date:
    • Site-wide: 36,110
  • Since beginning of last month:
    • Site-wide: 9,036

Population coding of valence in the basolateral amygdala

neuroscience more details view paper
  • Downloaded 805 times
  • Download rankings, all-time:
    • Site-wide: 33,924
    • In neuroscience: 4,491
  • Year to date:
    • Site-wide: 135,290
  • Since beginning of last month:
    • Site-wide: 58,985

DNA methylation-based immune cell deconvolution in solid tumors

bioinformatics more details view paper
  • Downloaded 792 times
  • Download rankings, all-time:
    • Site-wide: 34,677
    • In bioinformatics: 3,791
  • Year to date:
    • Site-wide: 72,724
  • Since beginning of last month:
    • Site-wide: 110,835

Novel pipeline of high-frequency neoantigens heathy donor-based validation in breast cancer

cancer biology more details view paper
  • Downloaded 762 times
  • Download rankings, all-time:
    • Site-wide: 36,652
    • In cancer biology: 991
  • Year to date:
    • Site-wide: 65,431
  • Since beginning of last month:
    • Site-wide: 111,262

A central amygdala-globus pallidus circuit conveys unconditioned stimulus information and controls fear learning

neuroscience more details view paper
  • Downloaded 713 times
  • Download rankings, all-time:
    • Site-wide: 40,139
    • In neuroscience: 5,466
  • Year to date:
    • Site-wide: 33,698
  • Since beginning of last month:
    • Site-wide: 20,437

The co-stimulation of anti-CD28 and IL-2 enhances the sensitivity of ELISPOT assays for detection of neoantigen-specific T cells in PBMC

immunology more details view paper
  • Downloaded 701 times
  • Download rankings, all-time:
    • Site-wide: 41,030
    • In immunology: 1,288
  • Year to date:
    • Site-wide: 23,136
  • Since beginning of last month:
    • Site-wide: 11,276

Genome profiles of lymphovascular breast cancer cells reveal multiple clonally differentiated outcomes with multi-regional LCM and G&T-seq

cancer biology more details view paper
  • Downloaded 631 times
  • Download rankings, all-time:
    • Site-wide: 47,032
    • In cancer biology: 1,334
  • Year to date:
    • Site-wide: 57,248
  • Since beginning of last month:
    • Site-wide: 40,798

Analysis of metagenome-assembled genomes from the mouse gut microbiota reveals distinctive strain-level characteristics

microbiology more details view paper
  • Downloaded 485 times
  • Download rankings, all-time:
    • Site-wide: 64,553
    • In microbiology: 4,175
  • Year to date:
    • Site-wide: 51,588
  • Since beginning of last month:
    • Site-wide: 32,707

Molecular profiles and mutation burden analysis in Chinese patients with gastric carcinoma

cancer biology more details view paper
  • Downloaded 481 times
  • Download rankings, all-time:
    • Site-wide: 65,163
    • In cancer biology: 1,890
  • Year to date:
    • Site-wide: 87,859
  • Since beginning of last month:
    • Site-wide: 59,093

Comprehensive and Integrated Genomic Characterization of Human Immunome in Cancer

immunology more details view paper
  • Downloaded 441 times
  • Download rankings, all-time:
    • Site-wide: 71,564
    • In immunology: 2,158
  • Year to date:
    • Site-wide: 53,363
  • Since beginning of last month:
    • Site-wide: 16,870

Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy Targets

cancer biology more details view paper
  • Downloaded 430 times
  • Download rankings, all-time:
    • Site-wide: 73,341
    • In cancer biology: 2,137
  • Year to date:
    • Site-wide: 70,267
  • Since beginning of last month:
    • Site-wide: 31,151

Identification of Cancer-associated Metabolic Vulnerabilities by Modeling Multi-objective Optimality in Metabolism

systems biology more details view paper
  • Downloaded 373 times
  • Download rankings, all-time:
    • Site-wide: 83,931
    • In systems biology: 1,916
  • Year to date:
    • Site-wide: 153,174
  • Since beginning of last month:
    • Site-wide: None

Metabolic features of mouse and human retinas: rods vs. cones, macula vs. periphery, retina vs. RPE

neuroscience more details view paper
  • Downloaded 370 times
  • Download rankings, all-time:
    • Site-wide: 84,511
    • In neuroscience: 12,598
  • Year to date:
    • Site-wide: 76,356
  • Since beginning of last month:
    • Site-wide: None

Defining Strawberry Uniformity using 3D Imaging and Genetic Mapping

bioinformatics more details view paper
  • Downloaded 368 times
  • Download rankings, all-time:
    • Site-wide: 84,810
    • In bioinformatics: 7,609
  • Year to date:
    • Site-wide: 102,225
  • Since beginning of last month:
    • Site-wide: 134,764

Bi-clustering based biological and clinical characterization of colorectal cancer in complementary to CMS classification

bioinformatics more details view paper
  • Downloaded 358 times
  • Download rankings, all-time:
    • Site-wide: 86,970
    • In bioinformatics: 7,742
  • Year to date:
    • Site-wide: 131,020
  • Since beginning of last month:
    • Site-wide: 112,869

A Comprehensive Survey of Mutations in Oesophageal Carcinoma Reveals Recurrent Neoantigens as Potential Immunotherapy Targets

immunology more details view paper
  • Downloaded 316 times
  • Download rankings, all-time:
    • Site-wide: 96,158
    • In immunology: 2,866
  • Year to date:
    • Site-wide: 71,436
  • Since beginning of last month:
    • Site-wide: 133,314

Intrinsic and extrinsic regulation of human fetal bone marrow haematopoiesis and perturbations in Down syndrome

developmental biology more details view paper
  • Downloaded 315 times
  • Download rankings, all-time:
    • Site-wide: 96,407
    • In developmental biology: 2,609
  • Year to date:
    • Site-wide: 18,281
  • Since beginning of last month:
    • Site-wide: 85,771

Impaired Fetal Lung Development can be Rescued by Administration of Extracellular Vesicles Derived from Amniotic Fluid Stem Cells

developmental biology more details view paper
  • Downloaded 303 times
  • Download rankings, all-time:
    • Site-wide: 99,186
    • In developmental biology: 2,679
  • Year to date:
    • Site-wide: 39,352
  • Since beginning of last month:
    • Site-wide: 29,694

RecO impedes RecG-SSB binding to impair the strand annealing recombination pathway in E.coli

molecular biology more details view paper
  • Downloaded 284 times
  • Download rankings, all-time:
    • Site-wide: 103,634
    • In molecular biology: 3,090
  • Year to date:
    • Site-wide: 113,234
  • Since beginning of last month:
    • Site-wide: 58,927

Verify Hub Genes of expression profile in aortic dissection

bioinformatics more details view paper
  • Downloaded 283 times
  • Download rankings, all-time:
    • Site-wide: 103,949
    • In bioinformatics: 8,836
  • Year to date:
    • Site-wide: 152,868
  • Since beginning of last month:
    • Site-wide: 110,710

Inhibition of mitochondrial respiration impairs nutrient consumption and metabolite transport in human retinal pigment epithelium

biochemistry more details view paper
  • Downloaded 282 times
  • Download rankings, all-time:
    • Site-wide: 104,105
    • In biochemistry: 3,028
  • Year to date:
    • Site-wide: 70,385
  • Since beginning of last month:
    • Site-wide: 88,761

Bimodality of gene expression in cancer patient tumors as interpretable biomarkers for drug sensitivity

cancer biology more details view paper
  • Downloaded 242 times
  • Download rankings, all-time:
    • Site-wide: 113,832
    • In cancer biology: 3,456
  • Year to date:
    • Site-wide: 62,485
  • Since beginning of last month:
    • Site-wide: 127,599

Related Topics of a Novel TCR-based Cancer Detection Approach

bioinformatics more details view paper
  • Downloaded 237 times
  • Download rankings, all-time:
    • Site-wide: 115,280
    • In bioinformatics: 9,503
  • Year to date:
    • Site-wide: 103,736
  • Since beginning of last month:
    • Site-wide: 98,823

Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

developmental biology more details view paper
  • Downloaded 229 times
  • Download rankings, all-time:
    • Site-wide: 117,181
    • In developmental biology: 3,184
  • Year to date:
    • Site-wide: 63,511
  • Since beginning of last month:
    • Site-wide: 43,062

Sex-specific stress-related behavioral phenotypes and central amygdala dysfunction in a mouse model of 16p11.2 microdeletion

neuroscience more details view paper
  • Downloaded 229 times
  • Download rankings, all-time:
    • Site-wide: 117,258
    • In neuroscience: 17,686
  • Year to date:
    • Site-wide: 76,627
  • Since beginning of last month:
    • Site-wide: 99,810

Two Types of Cinnamoyl-CoA Reductase Function Divergently in Tissue Lignification, Phenylpropanoids Flux Control, and Inter-pathway Cross-talk with Glucosinolates as Revealed in Brassica napus

plant biology more details view paper
  • Downloaded 228 times
  • Download rankings, all-time:
    • Site-wide: 117,411
    • In plant biology: 3,228
  • Year to date:
    • Site-wide: 28,275
  • Since beginning of last month:
    • Site-wide: 96,197

Structural changes in the gut microbiome of short-term and long-term medical workers compared to normal controls

microbiology more details view paper
  • Downloaded 207 times
  • Download rankings, all-time:
    • Site-wide: 122,820
    • In microbiology: 9,046
  • Year to date:
    • Site-wide: 134,797
  • Since beginning of last month:
    • Site-wide: None

Development of next-generation sequencing-based sterility test

microbiology more details view paper
  • Downloaded 191 times
  • Download rankings, all-time:
    • Site-wide: 126,745
    • In microbiology: 9,407
  • Year to date:
    • Site-wide: 41,340
  • Since beginning of last month:
    • Site-wide: 99,045

A dinucleotide tag-based parallel reporter gene assay method

molecular biology more details view paper
  • Downloaded 45 times
  • Download rankings, all-time:
    • Site-wide: 152,748
    • In molecular biology: 4,624
  • Year to date:
    • Site-wide: 121,984
  • Since beginning of last month:
    • Site-wide: 20,842

Neurotensin neurons in the central extended amygdala control energy balance

neuroscience more details view paper
  • Downloaded 3 times
  • Download rankings, all-time:
    • Site-wide: 155,313
    • In neuroscience: 23,172
  • Year to date:
    • Site-wide: 155,279
  • Since beginning of last month:
    • Site-wide: 90,033

IntroSpect: motif-guided immunopeptidome database building tool to improve the sensitivity of HLA binding peptide identification

bioinformatics more details view paper
  • Downloaded 0 times
  • Download rankings, all-time:
    • Site-wide: 155,780
    • In bioinformatics: 11,714
  • Year to date:
    • Site-wide: 155,693
  • Since beginning of last month:
    • Site-wide: 124,967

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