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Author: Leif Groop

Rankings

  • All-time downloads: 20,508 (rank: 2,656 out of 381,050)
  • Categories:
    • cell biology: 1,828 (rank: 2,033 (tie) out of 28,321)
    • genetics: 12,332 (rank: 903 out of 35,227)
    • genomics: 5,437 (rank: 3,187 (tie) out of 40,646)
    • molecular biology: 460 (rank: 8,630 (tie) out of 19,756)
    • systems biology: 451 (rank: 6,432 (tie) out of 11,228)

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Preprints

A reference panel of 64,976 haplotypes for genotype imputation

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Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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TCF7L2 is a master regulator of insulin production and processing

cell biology more details view paper
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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

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Influence of genetic variants on gene expression in human pancreatic islets – implications for type 2 diabetes

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Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
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Haplotype sharing provides insights into fine-scale population history and disease in Finland

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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

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Heterozygous RFX6 protein truncating variants cause Maturity-Onset Diabetes of the Young (MODY) with reduced penetrance

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Turning vice into virtue: Using Batch-Effects to Detect Errors in Large Genomic Datasets

genomics more details view paper
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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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Islet Gene View - a tool to facilitate islet research

molecular biology more details view paper
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Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes

systems biology more details view paper
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Human pancreatic β cell lncRNAs control cell-specific regulatory networks

genomics more details view paper
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Exome-wide association study on Albuminuria identifies a novel rare variant in CUBN and additional genes, in 33,985 Europeans with and without diabetes

genetics more details view paper
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