Author: Jaakko Kaprio

Downloads per author, site-wide

Preprints

Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

• Downloaded 8,606 times
• Download rankings, all-time:
  • Site-wide: 914
  • In genetics: 27
• Year to date:
  • Site-wide: 50,429
• Since beginning of last month:
  • Site-wide: None

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,247 times
• Download rankings, all-time:
  • Site-wide: 3,468
  • In genetics: 149
• Year to date:
  • Site-wide: 25,947
• Since beginning of last month:
  • Site-wide: 25,762

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 2,526 times
• Download rankings, all-time:
  • Site-wide: 4,938
  • In genetics: 229
• Year to date:
  • Site-wide: 17,041
• Since beginning of last month:
  • Site-wide: 17,453

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

• Downloaded 2,118 times
• Download rankings, all-time:
  • Site-wide: 6,406
  • In genetics: 319
• Year to date:
  • Site-wide: 18,171
• Since beginning of last month:
  • Site-wide: 15,160

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

• Downloaded 1,867 times
• Download rankings, all-time:
  • Site-wide: 7,712
  • In genetics: 369
• Year to date:
  • Site-wide: 62,350
• Since beginning of last month:
  • Site-wide: 64,490

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,704 times
• Download rankings, all-time:
  • Site-wide: 8,888
  • In genetics: 440
• Year to date:
  • Site-wide: 56,079
• Since beginning of last month:
  • Site-wide: 54,444

Haplotype sharing provides insights into fine-scale population history and disease in Finland

• Downloaded 1,102 times
• Download rankings, all-time:
  • Site-wide: 17,053
  • In genetics: 867
• Year to date:
  • Site-wide: 62,245
• Since beginning of last month:
  • Site-wide: 54,621

EpiSmokEr: A robust classifier to determine smoking status from DNA methylation data

• Downloaded 1,075 times
• Download rankings, all-time:
  • Site-wide: 17,681
  • In bioinformatics: 2,146
• Year to date:
  • Site-wide: 62,933
• Since beginning of last month:
  • Site-wide: 53,303

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

• Downloaded 825 times
• Download rankings, all-time:
  • Site-wide: 25,905
  • In genetics: 1,287
• Year to date:
  • Site-wide: 62,319
• Since beginning of last month:
  • Site-wide: 64,434

Polygenic risk, susceptibility genes, and breast cancer over the life course

• Downloaded 816 times
• Download rankings, all-time:
  • Site-wide: 26,307
  • In oncology: 26
• Year to date:
  • Site-wide: 30,651
• Since beginning of last month:
  • Site-wide: 31,247

Genetic Association Study of Childhood Aggression across raters, instruments and age

• Downloaded 796 times
• Download rankings, all-time:
  • Site-wide: 27,196
  • In genomics: 2,565
• Year to date:
  • Site-wide: 33,765
• Since beginning of last month:
  • Site-wide: 28,735

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 633 times
• Download rankings, all-time:
  • Site-wide: 37,197
  • In genetics: 1,813
• Year to date:
  • Site-wide: 14,693
• Since beginning of last month:
  • Site-wide: 5,861

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

• Downloaded 627 times
• Download rankings, all-time:
  • Site-wide: 37,631
  • In genomics: 3,220
• Year to date:
  • Site-wide: 25,451
• Since beginning of last month:
  • Site-wide: 20,150

Polygenic risk score of alcohol consumption predicts alcohol-related morbidity and all-cause mortality

• Downloaded 608 times
• Download rankings, all-time:
  • Site-wide: 39,125
  • In genomics: 3,311
• Year to date:
  • Site-wide: 50,628
• Since beginning of last month:
  • Site-wide: 37,610

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

• Downloaded 551 times
• Download rankings, all-time:
  • Site-wide: 44,312
  • In genomics: 3,613
• Year to date:
  • Site-wide: 43,365
• Since beginning of last month:
  • Site-wide: 28,607

Metabolic signatures of birth weight in 18288 adolescents and adults

• Downloaded 542 times
• Download rankings, all-time:
  • Site-wide: 45,186
  • In systems biology: 1,055
• Year to date:
  • Site-wide: 104,464
• Since beginning of last month:
  • Site-wide: None

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 474 times
• Download rankings, all-time:
  • Site-wide: 52,746
  • In genetics: 2,508
• Year to date:
  • Site-wide: 90,181
• Since beginning of last month:
  • Site-wide: 78,688

The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study

• Downloaded 423 times
• Download rankings, all-time:
  • Site-wide: 59,587
  • In epidemiology: 2,531
• Year to date:
  • Site-wide: 115,969
• Since beginning of last month:
  • Site-wide: 102,110

Variants in regulatory elements of PDE4D associate with Major Mental Illness in the Finnish population

• Downloaded 409 times
• Download rankings, all-time:
  • Site-wide: 61,651
  • In genetics: 2,914
• Year to date:
  • Site-wide: 97,509
• Since beginning of last month:
  • Site-wide: None

Identification of Slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

• Downloaded 407 times
• Download rankings, all-time:
  • Site-wide: 61,977
  • In genetics: 2,927
• Year to date:
  • Site-wide: 78,136
• Since beginning of last month:
  • Site-wide: None

Teacher-rated aggression and co-occurring problems and behaviors among schoolchildren: A comparison of four population-based European cohorts

• Downloaded 349 times
• Download rankings, all-time:
  • Site-wide: 71,351
  • In epidemiology: 2,964
• Year to date:
  • Site-wide: 51,177
• Since beginning of last month:
  • Site-wide: 31,262

Polygenic Risk for Alcohol Misuse is Moderated by Romantic Partnerships: Primarily in Men

• Downloaded 349 times
• Download rankings, all-time:
  • Site-wide: 71,459
  • In epidemiology: 2,963
• Year to date:
  • Site-wide: 96,421
• Since beginning of last month:
  • Site-wide: 61,513

An integrative machine learning approach to discovering multi-level molecular mechanisms of obesity using data from monozygotic twin pairs

• Downloaded 318 times
• Download rankings, all-time:
  • Site-wide: 77,124
  • In epidemiology: 3,174
• Year to date:
  • Site-wide: 70,244
• Since beginning of last month:
  • Site-wide: 30,888

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

• Downloaded 247 times
• Download rankings, all-time:
  • Site-wide: 91,722
  • In genetics: 4,183
• Year to date:
  • Site-wide: 39,494
• Since beginning of last month:
  • Site-wide: 34,361

Long-Term Leisure-Time Physical Activity and Other Health Habits as Predictors of Objectively Monitored Late-Life Physical Activity: A 40-Year Twin Study

• Downloaded 246 times
• Download rankings, all-time:
  • Site-wide: 91,881
  • In epidemiology: 3,717
• Year to date:
  • Site-wide: 85,742
• Since beginning of last month:
  • Site-wide: 84,982

Ketone body 3-hydroxybutyrate: a biomarker of aggression?

• Downloaded 194 times
• Download rankings, all-time:
  • Site-wide: 103,087
  • In epidemiology: 4,206
• Year to date:
  • Site-wide: 74,707
• Since beginning of last month:
  • Site-wide: 58,340

Polygenic score for physical activity provides odds for multiple common diseases

• Downloaded 37 times
• Download rankings, all-time:
  • Site-wide: 127,619
  • In sports medicine: 59
• Year to date:
  • Site-wide: 35,211
• Since beginning of last month:
  • Site-wide: 11,773

Blood and skeletal muscle ageing determined by epigenetic clocks and their associations with physical activity and functioning

• Downloaded 33 times
• Download rankings, all-time:
  • Site-wide: 127,698
  • In epidemiology: 5,131
• Year to date:
  • Site-wide: 38,370
• Since beginning of last month:
  • Site-wide: 13,390