Author: Seth A Ament

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Preprints

Single cell epigenomic atlas of the developing human brain and organoids

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  • Site-wide: 1,484
  • In developmental biology: 9
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  • Site-wide: 1,652
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  • Site-wide: 6,870

An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types

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  • Site-wide: 1,745
  • In neuroscience: 82
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  • Site-wide: 1,485
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  • Site-wide: 4,562

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

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  • Site-wide: 1,767
  • In neuroscience: 86
• Year to date:
  • Site-wide: 1,216
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  • Site-wide: 1,552

A multimodal cell census and atlas of the mammalian primary motor cortex

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  • Site-wide: 2,678
  • In neuroscience: 156
• Year to date:
  • Site-wide: 1,726
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  • Site-wide: 1,822

Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorders

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  • Site-wide: 10,422
  • In genetics: 433
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  • Site-wide: 81,053
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Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data Across 27 Tissue Types

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  • Site-wide: 13,178
  • In bioinformatics: 1,460
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  • Site-wide: 105,274
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  • Site-wide: 147,961

Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntingtons Disease

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  • Site-wide: 33,081
  • In neuroscience: 4,318
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  • Site-wide: 49,989

Genome-scale transcriptional regulatory network models for the mouse and human striatum predict roles for SMAD3 and other transcription factors in Huntington's disease

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  • Site-wide: 34,560
  • In systems biology: 702
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  • Site-wide: 136,367
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  • Site-wide: 122,160

Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty

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  • Site-wide: 47,648
  • In genetics: 2,048
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  • Site-wide: 129,092
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  • Site-wide: 150,018

Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntington's disease mutations

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  • Site-wide: 52,353
  • In genomics: 3,944
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  • Site-wide: 27,790
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  • Site-wide: 35,161

Peripheral Htt silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's Disease

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  • Site-wide: 53,839
  • In neuroscience: 7,632
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  • Site-wide: 117,097
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  • Site-wide: 137,984

gEAR: gene Expression Analysis Resource portal for community-driven, multi-omic data exploration

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  • Site-wide: 69,126
  • In bioinformatics: 6,540
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  • Site-wide: 39,305
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  • Site-wide: 67,750

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease

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  • Site-wide: 85,131
  • In neuroscience: 12,606
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  • Site-wide: 160,934
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  • Site-wide: 158,824

Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the prenatal human hypothalamus

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  • Site-wide: 117,562
  • In neuroscience: 17,633
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  • Site-wide: 34,771
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  • Site-wide: 50,551

Regulome-wide association study identifies enhancer properties associated with risk for schizophrenia

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  • Site-wide: 126,864
  • In genomics: 6,960
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  • Site-wide: 41,328
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Cochlear organoids reveal epigenetic and transcriptional programs of postnatal hair cell differentiation from supporting cells

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  • Site-wide: 135,288
  • In developmental biology: 3,657
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  • Site-wide: 49,110
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A rare variant in D-amino acid oxidase implicates NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder

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  • Site-wide: 139,191
  • In psychiatry and clinical psychology: 759
• Year to date:
  • Site-wide: 53,716
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  • Site-wide: 69,996

GWAS meta-analysis reveals dual neuronal and immunological etiology for pain susceptibility

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  • Site-wide: 154,126
  • In genetic and genomic medicine: 970
• Year to date:
  • Site-wide: 84,262
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  • Site-wide: 133,068

Activation of Npas1-neurons in the Ventral Pallidum Mediates Stress Susceptibility

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  • Site-wide: 157,253
  • In neuroscience: 23,410
• Year to date:
  • Site-wide: 97,852
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  • Site-wide: 11,401