Author: Seth Ament

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Preprints

Single cell epigenomic atlas of the developing human brain and organoids

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  • Site-wide: 1,773
  • In developmental biology: 10
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An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types

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  • Site-wide: 1,963
  • In neuroscience: 82
• Year to date:
  • Site-wide: 5,741
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  • Site-wide: 9,378

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

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  • Site-wide: 1,986
  • In neuroscience: 84
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A multimodal cell census and atlas of the mammalian primary motor cortex

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  • Site-wide: 3,034
  • In neuroscience: 169
• Year to date:
  • Site-wide: 22,125
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Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorders

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  • Site-wide: 12,949
  • In genetics: 482
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  • Site-wide: 174,737
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Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data Across 27 Tissue Types

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  • Site-wide: 17,109
  • In bioinformatics: 1,823
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Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntingtons Disease

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  • Site-wide: 32,272
  • In neuroscience: 4,037
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  • Site-wide: 201,305
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  • Site-wide: 52,849

Genome-scale transcriptional regulatory network models for the mouse and human striatum predict roles for SMAD3 and other transcription factors in Huntington's disease

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  • Site-wide: 45,045
  • In systems biology: 872
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  • Site-wide: 204,118

gEAR: gene Expression Analysis Resource portal for community-driven, multi-omic data exploration

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  • Site-wide: 56,468
  • In bioinformatics: 5,565
• Year to date:
  • Site-wide: 112,319
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  • Site-wide: 78,567

Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus

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  • Site-wide: 57,785
  • In neuroscience: 8,582
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  • Site-wide: 5,416
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  • Site-wide: 10,084

Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntington's disease mutations

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  • Site-wide: 59,257
  • In genomics: 4,132
• Year to date:
  • Site-wide: 157,094
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  • Site-wide: 129,773

Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty

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  • Site-wide: 62,101
  • In genetics: 2,382
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  • Site-wide: 194,806
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Peripheral Htt silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's Disease

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  • Site-wide: 68,206
  • In neuroscience: 9,439
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Cochlear organoids reveal epigenetic and transcriptional programs of postnatal hair cell differentiation from supporting cells

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  • Site-wide: 89,374
  • In developmental biology: 2,328
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  • Site-wide: 28,848

The BRAIN Initiative Cell Census Data Ecosystem: A User's Guide

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  • Site-wide: 99,960
  • In bioinformatics: 10,316
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  • Site-wide: 5,555
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  • Site-wide: 9,537

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease

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  • Site-wide: 112,662
  • In neuroscience: 16,258
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Regulome-wide association study identifies enhancer properties associated with risk for schizophrenia

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  • Site-wide: 118,070
  • In genomics: 6,842
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  • Site-wide: 43,611
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  • Site-wide: 36,597

GWAS meta-analysis reveals dual neuronal and immunological etiology for pain susceptibility

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  • Site-wide: 125,785
  • In genetic and genomic medicine: 882
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  • Site-wide: 24,994
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  • Site-wide: 112,755

Molecular, circuit, and stress response characterization of Ventral Pallidum Npas1-neurons

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  • Site-wide: 145,532
  • In neuroscience: 22,321
• Year to date:
  • Site-wide: 43,823
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  • Site-wide: 72,100

A rare variant in D-amino acid oxidase implicates NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder

• Downloaded 337 times
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  • Site-wide: 149,220
  • In psychiatry and clinical psychology: 900
• Year to date:
  • Site-wide: 120,041
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  • Site-wide: 58,612

Negative emotional behavior during fentanyl abstinence is mediated by adaptations in nucleus accumbens neuron subtypes

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  • Site-wide: 160,854
  • In neuroscience: 23,561
• Year to date:
  • Site-wide: 149,963
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  • Site-wide: 115,169

The Neuroscience Multi-Omic Archive: A BRAIN Initiative resource for single-cell transcriptomic and epigenomic data from the mammalian brain

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  • Site-wide: 182,203
  • In genomics: 8,823
• Year to date:
  • Site-wide: 86,329
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  • Site-wide: 34,168

Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population

• Downloaded 210 times
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  • Site-wide: 185,529
  • In psychiatry and clinical psychology: 1,231
• Year to date:
  • Site-wide: 69,808
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  • Site-wide: 134,593

Early-childhood inflammation blunts the transcriptional maturation of cerebellar neurons

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  • Site-wide: 191,606
  • In genomics: 9,078
• Year to date:
  • Site-wide: 117,920
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  • Site-wide: 73,601