Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 67,027 bioRxiv papers from 295,009 authors.

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Preprints

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

• Downloaded 1,673 times
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  • In genetics: 282 out of 3,772
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  • Site-wide: 25,491 out of 67,027
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  • Site-wide: 40,704 out of 67,027

Model-based analysis of positive selection significantly expands the list of cancer driver genes, including RNA methyltransferases

• Downloaded 821 times
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  • Site-wide: 10,515 out of 67,027
  • In genomics: 1,539 out of 4,553
• Year to date:
  • Site-wide: 13,738 out of 67,027
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  • Site-wide: 39,821 out of 67,027

Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography

• Downloaded 801 times
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  • Site-wide: 10,883 out of 67,027
  • In microbiology: 487 out of 5,400
• Year to date:
  • Site-wide: 37,252 out of 67,027
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  • Site-wide: 43,246 out of 67,027

Spike-timing pattern operates as gamma-distribution across cell types, regions and animal species and is essential for naturally-occurring cognitive states

• Downloaded 773 times
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  • Site-wide: 11,517 out of 67,027
  • In neuroscience: 1,856 out of 12,010
• Year to date:
  • Site-wide: 22,930 out of 67,027
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  • Site-wide: 21,864 out of 67,027

Morphology of Mitochondria in Spatially Restricted Axons Revealed by Cryo-Electron Tomography

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  • In neuroscience: 2,156 out of 12,010
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  • Site-wide: 25,769 out of 67,027
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  • Site-wide: 29,332 out of 67,027

MBIR: A Cryo-electron Tomography 3D Reconstruction Method that Effectively Minimizes Missing Wedge Artifacts and Restores Missing Information

• Downloaded 700 times
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  • Site-wide: 13,300 out of 67,027
  • In biophysics: 412 out of 2,839
• Year to date:
  • Site-wide: 12,032 out of 67,027
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  • Site-wide: 42,447 out of 67,027

High-resolution view of the type III secretion export apparatus in situ reveals membrane remodeling and a secretion pathway

• Downloaded 627 times
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  • Site-wide: 15,506 out of 67,027
  • In microbiology: 781 out of 5,400
• Year to date:
  • Site-wide: 4,317 out of 67,027
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  • Site-wide: 5,446 out of 67,027

Using a bar-coded AAV capsid library to select for novel clinically relevant gene therapy vectors

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  • In genetics: 1,466 out of 3,772
• Year to date:
  • Site-wide: 6,678 out of 67,027
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  • Site-wide: 7,710 out of 67,027

Structure of a novel dimeric SET domain methyltransferase that regulates cell motility

• Downloaded 463 times
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  • Site-wide: 23,004 out of 67,027
  • In biochemistry: 538 out of 1,970
• Year to date:
  • Site-wide: 23,389 out of 67,027
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  • Site-wide: 32,523 out of 67,027

Loss of a doublecortin (DCX) domain containing protein causes structural defects in a tubulin-based organelle of Toxoplasma gondii and impairs host cell invasion.

• Downloaded 435 times
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  • In cell biology: 1,126 out of 3,246
• Year to date:
  • Site-wide: 55,196 out of 67,027
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  • Site-wide: 65,149 out of 67,027

In situ structures of periplasmic flagella in Borrelia reveals conformational changes essential for flagellar rotation

• Downloaded 420 times
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  • In microbiology: 1,458 out of 5,400
• Year to date:
  • Site-wide: 8,443 out of 67,027
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  • Site-wide: 58,614 out of 67,027

Neural code uses self-information principle to organize the brain's universal cell-assembly coding

• Downloaded 410 times
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  • Site-wide: 26,418 out of 67,027
  • In neuroscience: 4,537 out of 12,010
• Year to date:
  • Site-wide: 35,419 out of 67,027
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  • Site-wide: 13,870 out of 67,027

In situ structures of periplasmic flagella reveal a distinct cytoplasmic ATPase complex in Borrelia burgdorferi

• Downloaded 386 times
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  • Site-wide: 28,155 out of 67,027
  • In microbiology: 1,660 out of 5,400
• Year to date:
  • Site-wide: 38,893 out of 67,027
• Since beginning of last month:
  • Site-wide: 26,602 out of 67,027

Stability and function of a putative microtubule organizing center in the human parasite Toxoplasma gondii

• Downloaded 379 times
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  • Site-wide: 28,758 out of 67,027
  • In cell biology: 1,332 out of 3,246
• Year to date:
  • Site-wide: 56,021 out of 67,027
• Since beginning of last month:
  • Site-wide: 56,771 out of 67,027

Discovery of an essential mycobacterial polar growth factor involved in cell envelope integrity and lipomannan and lipoarabinomannan transport

• Downloaded 374 times
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  • Site-wide: 29,146 out of 67,027
  • In microbiology: 1,739 out of 5,400
• Year to date:
  • Site-wide: 10,262 out of 67,027
• Since beginning of last month:
  • Site-wide: 19,755 out of 67,027

Ex vivo dynamics of human glioblastoma cells in a microvasculature-on-a-chip system correlates with tumor heterogeneity and subtypes

• Downloaded 355 times
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  • Site-wide: 30,722 out of 67,027
  • In bioengineering: 557 out of 1,345
• Year to date:
  • Site-wide: 30,481 out of 67,027
• Since beginning of last month:
  • Site-wide: 54,805 out of 67,027

Genome-wide association study of plasma triglycerides, phospholipids and relation to cardio-metabolic risk factors

• Downloaded 349 times
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  • Site-wide: 31,255 out of 67,027
  • In epidemiology: 467 out of 1,556
• Year to date:
  • Site-wide: 11,445 out of 67,027
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  • Site-wide: 21,566 out of 67,027

A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers

• Downloaded 325 times
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  • Site-wide: 33,548 out of 67,027
  • In cell biology: 1,573 out of 3,246
• Year to date:
  • Site-wide: 12,845 out of 67,027
• Since beginning of last month:
  • Site-wide: 11,801 out of 67,027

Inhibition of Intracellular Lipolysis Promotes Cancer Cell Adaptation to Hypoxia

• Downloaded 315 times
• Download rankings, all-time:
  • Site-wide: 34,523 out of 67,027
  • In biochemistry: 902 out of 1,970
• Year to date:
  • Site-wide: 58,923 out of 67,027
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  • Site-wide: 61,165 out of 67,027

A systems approach to refine disease taxonomy by integrating phenotypic and molecular networks

• Downloaded 303 times
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  • Site-wide: 35,664 out of 67,027
  • In bioinformatics: 4,409 out of 6,609
• Year to date:
  • Site-wide: 54,986 out of 67,027
• Since beginning of last month:
  • Site-wide: 63,140 out of 67,027

Deletion of Lats 1 and 2 in mouse pancreatic acinar cells induces pancreatic fibrosis and inflammation

• Downloaded 279 times
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  • Site-wide: 38,142 out of 67,027
  • In molecular biology: 1,128 out of 2,138
• Year to date:
  • Site-wide: 15,937 out of 67,027
• Since beginning of last month:
  • Site-wide: 20,393 out of 67,027

TgCentrin2 is required for invasion and replication in the human parasite Toxoplasma gondii

• Downloaded 270 times
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  • Site-wide: 39,264 out of 67,027
  • In cell biology: 1,885 out of 3,246
• Year to date:
  • Site-wide: 24,971 out of 67,027
• Since beginning of last month:
  • Site-wide: 31,981 out of 67,027

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

• Downloaded 253 times
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  • Site-wide: 41,201 out of 67,027
  • In genomics: 3,594 out of 4,553
• Year to date:
  • Site-wide: 32,508 out of 67,027
• Since beginning of last month:
  • Site-wide: 50,826 out of 67,027

Inhibition of ADORA1 attenuates hepatic steatosis by gut microbiota-derived acetic acid from Astragalus polysaccharides

• Downloaded 217 times
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  • Site-wide: 45,777 out of 67,027
  • In physiology: 388 out of 842
• Year to date:
  • Site-wide: 22,554 out of 67,027
• Since beginning of last month:
  • Site-wide: 38,868 out of 67,027

Regulation by HSP70/90 in the different tissues and testis development of male cattle (Cattle-yak and Yak)

• Downloaded 214 times
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  • Site-wide: 46,202 out of 67,027
  • In biochemistry: 1,303 out of 1,970
• Year to date:
  • Site-wide: 45,428 out of 67,027
• Since beginning of last month:
  • Site-wide: 27,804 out of 67,027

Establishing Rod-Shape from Spherical, Peptidoglycan-Deficient Bacterial Spores

• Downloaded 199 times
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  • Site-wide: 48,124 out of 67,027
  • In microbiology: 3,402 out of 5,400
• Year to date:
  • Site-wide: 25,036 out of 67,027
• Since beginning of last month:
  • Site-wide: 2,632 out of 67,027

The Vibrio H-ring facilitates the outer membrane penetration of polar-sheathed flagellum

• Downloaded 194 times
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  • Site-wide: 48,827 out of 67,027
  • In microbiology: 3,461 out of 5,400
• Year to date:
  • Site-wide: 54,208 out of 67,027
• Since beginning of last month:
  • Site-wide: 63,055 out of 67,027

RNA Polymerase II Independent Recruitment of SPT6 at Transcription Start Sites in Arabidopsis

• Downloaded 172 times
• Download rankings, all-time:
  • Site-wide: 51,992 out of 67,027
  • In molecular biology: 1,579 out of 2,138
• Year to date:
  • Site-wide: 41,275 out of 67,027
• Since beginning of last month:
  • Site-wide: 39,016 out of 67,027

methylSCOPA and META-methylSCOPA: software for the analysis and aggregation of epigenome-wide association studies of multiple correlated phenotypes

• Downloaded 172 times
• Download rankings, all-time:
  • Site-wide: 51,937 out of 67,027
  • In bioinformatics: 5,662 out of 6,609
• Year to date:
  • Site-wide: 29,698 out of 67,027
• Since beginning of last month:
  • Site-wide: 26,000 out of 67,027

IMCC: Quantitative Analysis of the Inter-module Connectivity for Bio-network

• Downloaded 169 times
• Download rankings, all-time:
  • Site-wide: 52,524 out of 67,027
  • In systems biology: 1,587 out of 1,861
• Year to date:
  • Site-wide: 30,363 out of 67,027
• Since beginning of last month:
  • Site-wide: 59,460 out of 67,027

The C. elegans SMOC-1 protein acts cell non-autonomously to promote bone morphogenetic protein signaling

• Downloaded 158 times
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  • Site-wide: 54,071 out of 67,027
  • In genetics: 3,176 out of 3,772
• Year to date:
  • Site-wide: 52,317 out of 67,027
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  • Site-wide: 58,992 out of 67,027

Effect of inbreeding on type 2 diabetes-related metabolites in a Dutch genetic isolate

• Downloaded 157 times
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  • Site-wide: 54,129 out of 67,027
  • In genetics: 3,183 out of 3,772
• Year to date:
  • Site-wide: 32,629 out of 67,027
• Since beginning of last month:
  • Site-wide: 47,449 out of 67,027

Quantitative investigation of factors relevant to the T cell spot test for tuberculosis infection in active tuberculosis

• Downloaded 140 times
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  • Site-wide: 56,606 out of 67,027
  • In epidemiology: 1,225 out of 1,556
• Year to date:
  • Site-wide: 36,594 out of 67,027
• Since beginning of last month:
  • Site-wide: 52,964 out of 67,027

Recessive genetic effects on type 2 diabetes-related metabolites in a consanguineous population

• Downloaded 136 times
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  • Site-wide: 57,233 out of 67,027
  • In genetics: 3,328 out of 3,772
• Year to date:
  • Site-wide: 37,579 out of 67,027
• Since beginning of last month:
  • Site-wide: 54,699 out of 67,027

Repulsive Guidance Molecule Acts in Axon Branching in Caenorhabditis elegans

• Downloaded 116 times
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  • Site-wide: 59,868 out of 67,027
  • In developmental biology: 1,837 out of 1,987
• Year to date:
  • Site-wide: 61,379 out of 67,027
• Since beginning of last month:
  • Site-wide: 64,334 out of 67,027

An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete

• Downloaded 76 times
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  • Site-wide: 64,047 out of 67,027
  • In biophysics: 2,728 out of 2,839
• Year to date:
  • Site-wide: 56,729 out of 67,027
• Since beginning of last month:
  • Site-wide: 3,435 out of 67,027

Synergistic effect: a common theme in mixed-species litter decomposition

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  • Site-wide: 64,470 out of 67,027
  • In ecology: 2,669 out of 2,857
• Year to date:
  • Site-wide: 58,523 out of 67,027
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  • Site-wide: 20,233 out of 67,027