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Author: Ian A. Wilson

  • ORCiD: http://orcid.org/0000-0002-6469-2419
  • Most recently observed institution: Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Rankings

  • All-time downloads: 39,960 (rank: 4,427 )
  • Categories:
    • biochemistry: 487 (rank: 12,814 (tie) )
    • bioengineering: 323 (rank: 11,456 (tie) )
    • biophysics: 277 (rank: 17,528 (tie) )
    • immunology: 10,159 (rank: 875 )
    • infectious diseases: 1,189 (rank: 23,155 (tie) )
    • microbiology: 26,892 (rank: 550 )
    • molecular biology: 229 (rank: 23,944 (tie) )
    • neuroscience: 404 (rank: 56,038 (tie) )

Downloads per author, site-wide

Preprints

Targeted isolation of panels of diverse human broadly neutralizing antibodies against SARS-like viruses

immunology more details view paper

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Robust de novo design of protein binding proteins from target structural information alone

synthetic biology more details view paper

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Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

microbiology more details view paper
  • Downloaded 5,985 times
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    • Site-wide: 1,846
    • In microbiology: 158
  • Year to date:
    • Site-wide: 32,290
  • Since beginning of last month:
    • Site-wide: 6,117

Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections

microbiology more details view paper
  • Downloaded 5,242 times
  • Download rankings, all-time:
    • Site-wide: 2,205
    • In microbiology: 179
  • Year to date:
    • Site-wide: 11,000
  • Since beginning of last month:
    • Site-wide: 66,149

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV

microbiology more details view paper
  • Downloaded 4,174 times
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    • Site-wide: 3,045
    • In microbiology: 220
  • Year to date:
    • Site-wide: 77,462
  • Since beginning of last month:
    • Site-wide: 96,565

Structural basis of a public antibody response to SARS-CoV-2

microbiology more details view paper
  • Downloaded 2,092 times
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    • Site-wide: 8,175
    • In microbiology: 493
  • Year to date:
    • Site-wide: 18,314
  • Since beginning of last month:
    • Site-wide: 30,638

A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model

immunology more details view paper
  • Downloaded 2,042 times
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    • Site-wide: 8,449
    • In immunology: 278
  • Year to date:
    • Site-wide: 11,974
  • Since beginning of last month:
    • Site-wide: 10,052

Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates

microbiology more details view paper
  • Downloaded 1,759 times
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    • Site-wide: 10,585
    • In microbiology: 624
  • Year to date:
    • Site-wide: 5,881
  • Since beginning of last month:
    • Site-wide: 15,054

A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes

immunology more details view paper
  • Downloaded 1,426 times
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    • Site-wide: 14,409
    • In immunology: 463
  • Year to date:
    • Site-wide: 1,894
  • Since beginning of last month:
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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity

infectious diseases more details view paper
  • Downloaded 1,189 times
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    • Site-wide: 18,929
    • In infectious diseases: 1,847
  • Year to date:
    • Site-wide: 12,198
  • Since beginning of last month:
    • Site-wide: 19,075

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

microbiology more details view paper
  • Downloaded 1,116 times
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    • Site-wide: 20,775
    • In microbiology: 1,220
  • Year to date:
    • Site-wide: 2,661
  • Since beginning of last month:
    • Site-wide: 29,874

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

microbiology more details view paper
  • Downloaded 1,104 times
  • Download rankings, all-time:
    • Site-wide: 21,107
    • In microbiology: 1,234
  • Year to date:
    • Site-wide: 20,279
  • Since beginning of last month:
    • Site-wide: 3,036

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 1,013 times
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    • Site-wide: 23,925
    • In microbiology: 1,431
  • Year to date:
    • Site-wide: 20,087
  • Since beginning of last month:
    • Site-wide: 53,895

Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts

immunology more details view paper
  • Downloaded 995 times
  • Download rankings, all-time:
    • Site-wide: 24,570
    • In immunology: 802
  • Year to date:
    • Site-wide: 90,235
  • Since beginning of last month:
    • Site-wide: 76,105

Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

immunology more details view paper
  • Downloaded 903 times
  • Download rankings, all-time:
    • Site-wide: 28,263
    • In immunology: 908
  • Year to date:
    • Site-wide: 3,608
  • Since beginning of last month:
    • Site-wide: 4,784

HIV-1 vaccine design through minimizing envelope metastability

microbiology more details view paper
  • Downloaded 697 times
  • Download rankings, all-time:
    • Site-wide: 40,487
    • In microbiology: 2,471
  • Year to date:
    • Site-wide: 109,313
  • Since beginning of last month:
    • Site-wide: None

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

microbiology more details view paper
  • Downloaded 673 times
  • Download rankings, all-time:
    • Site-wide: 42,404
    • In microbiology: 2,595
  • Year to date:
    • Site-wide: 36,662
  • Since beginning of last month:
    • Site-wide: 101,141

HIV-1 Envelope and MPER antibody structures in lipid assemblies

immunology more details view paper
  • Downloaded 629 times
  • Download rankings, all-time:
    • Site-wide: 46,283
    • In immunology: 1,392
  • Year to date:
    • Site-wide: 97,507
  • Since beginning of last month:
    • Site-wide: None

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

immunology more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 48,051
    • In immunology: 1,443
  • Year to date:
    • Site-wide: 99,230
  • Since beginning of last month:
    • Site-wide: 94,952

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

immunology more details view paper
  • Downloaded 589 times
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    • Site-wide: 50,158
    • In immunology: 1,503
  • Year to date:
    • Site-wide: 93,536
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    • Site-wide: None

Potent SARS-CoV-2 neutralizing antibodies selected from a human antibody library constructed decades ago

microbiology more details view paper
  • Downloaded 588 times
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    • Site-wide: 50,267
    • In microbiology: 3,166
  • Year to date:
    • Site-wide: 22,622
  • Since beginning of last month:
    • Site-wide: 5,609

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

immunology more details view paper
  • Downloaded 542 times
  • Download rankings, all-time:
    • Site-wide: 55,555
    • In immunology: 1,667
  • Year to date:
    • Site-wide: 141,889
  • Since beginning of last month:
    • Site-wide: 62,623

Influenza H3 and H1 hemagglutinins have different genetic barriers for resistance to broadly neutralizing stem antibodies

microbiology more details view paper
  • Downloaded 518 times
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    • Site-wide: 58,718
    • In microbiology: 3,785
  • Year to date:
    • Site-wide: 56,549
  • Since beginning of last month:
    • Site-wide: 63,598

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

immunology more details view paper
  • Downloaded 496 times
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    • Site-wide: 61,686
    • In immunology: 1,851
  • Year to date:
    • Site-wide: 80,313
  • Since beginning of last month:
    • Site-wide: 93,907

Rational design of hepatitis C virus E2 core nanoparticle vaccines

microbiology more details view paper
  • Downloaded 494 times
  • Download rankings, all-time:
    • Site-wide: 61,897
    • In microbiology: 4,034
  • Year to date:
    • Site-wide: 109,446
  • Since beginning of last month:
    • Site-wide: None

Bacterial Glycosyltransferase-mediated Cell-surface Chemoenzymatic Glycan Editing: Methods and Applications

biochemistry more details view paper
  • Downloaded 487 times
  • Download rankings, all-time:
    • Site-wide: 62,874
    • In biochemistry: 1,656
  • Year to date:
    • Site-wide: 102,227
  • Since beginning of last month:
    • Site-wide: 73,361

A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

microbiology more details view paper
  • Downloaded 481 times
  • Download rankings, all-time:
    • Site-wide: 63,615
    • In microbiology: 4,171
  • Year to date:
    • Site-wide: 9,057
  • Since beginning of last month:
    • Site-wide: None

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

immunology more details view paper
  • Downloaded 453 times
  • Download rankings, all-time:
    • Site-wide: 68,068
    • In immunology: 2,016
  • Year to date:
    • Site-wide: 151,460
  • Since beginning of last month:
    • Site-wide: None

Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 427 times
  • Download rankings, all-time:
    • Site-wide: 72,183
    • In microbiology: 4,886
  • Year to date:
    • Site-wide: 10,744
  • Since beginning of last month:
    • Site-wide: 20,835

Common antigenic motif recognized by human VH5-51/VL4-1 tau antibodies with distinct functionalities

neuroscience more details view paper
  • Downloaded 404 times
  • Download rankings, all-time:
    • Site-wide: 76,256
    • In neuroscience: 11,468
  • Year to date:
    • Site-wide: 129,987
  • Since beginning of last month:
    • Site-wide: 74,372

Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

immunology more details view paper
  • Downloaded 341 times
  • Download rankings, all-time:
    • Site-wide: 88,518
    • In immunology: 2,596
  • Year to date:
    • Site-wide: 138,693
  • Since beginning of last month:
    • Site-wide: 91,295

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

immunology more details view paper
  • Downloaded 340 times
  • Download rankings, all-time:
    • Site-wide: 88,636
    • In immunology: 2,602
  • Year to date:
    • Site-wide: 14,863
  • Since beginning of last month:
    • Site-wide: 19,239

Evidence of antigenic imprinting in sequential Sarbecovirus immunization

immunology more details view paper
  • Downloaded 337 times
  • Download rankings, all-time:
    • Site-wide: 89,417
    • In immunology: 2,624
  • Year to date:
    • Site-wide: 41,924
  • Since beginning of last month:
    • Site-wide: 49,231

Probing Affinity, Avidity, Anti-Cooperativity, and Competition in Antibody and Receptor Binding to the SARS-CoV-2 Spike by Single Particle Mass Analyses

immunology more details view paper
  • Downloaded 332 times
  • Download rankings, all-time:
    • Site-wide: 90,555
    • In immunology: 2,655
  • Year to date:
    • Site-wide: 15,413
  • Since beginning of last month:
    • Site-wide: 54,249

Broadening a SARS-CoV-1 neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution

bioengineering more details view paper
  • Downloaded 323 times
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    • Site-wide: 92,572
    • In bioengineering: 1,732
  • Year to date:
    • Site-wide: 16,002
  • Since beginning of last month:
    • Site-wide: 9,991

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

microbiology more details view paper
  • Downloaded 278 times
  • Download rankings, all-time:
    • Site-wide: 102,758
    • In microbiology: 7,400
  • Year to date:
    • Site-wide: 72,039
  • Since beginning of last month:
    • Site-wide: 19,391

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.

biophysics more details view paper
  • Downloaded 277 times
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    • Site-wide: 103,025
    • In biophysics: 3,940
  • Year to date:
    • Site-wide: 116,375
  • Since beginning of last month:
    • Site-wide: None

Neutralizing antibodies induced by first-generation gp41-stabilized HIV-1 envelope trimers and nanoparticles

microbiology more details view paper
  • Downloaded 251 times
  • Download rankings, all-time:
    • Site-wide: 109,358
    • In microbiology: 7,964
  • Year to date:
    • Site-wide: 45,851
  • Since beginning of last month:
    • Site-wide: None

N-glycolylneuraminic acid binding of avian H7 influenza A viruses

molecular biology more details view paper
  • Downloaded 229 times
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    • Site-wide: 114,727
    • In molecular biology: 3,387
  • Year to date:
    • Site-wide: 36,848
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    • Site-wide: 107,415

Homologous and heterologous serological response to the N-terminal domain of SARS-CoV-2

immunology more details view paper
  • Downloaded 125 times
  • Download rankings, all-time:
    • Site-wide: 139,129
    • In immunology: 4,112
  • Year to date:
    • Site-wide: 51,029
  • Since beginning of last month:
    • Site-wide: 48,721

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