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Author: Franziska Singer

  • ORCiD: http://orcid.org/0000-0002-6017-1595
  • Most recently observed institution: ETH Zurich, NEXUS Personalized Health Technologies, Wagistrasse 18, 8952 Schlieren, Switzerland; SIB Swiss Institute of Bioinformatics, Zurich, Switzerland

Rankings

  • All-time downloads: 36,510 (rank: 7,372 )
  • Categories:
    • bioinformatics: 9,142 (rank: 1,449 )
    • cancer biology: 13,771 (rank: 173 )
    • cell biology: 1,246 (rank: 11,263 (tie) )
    • epidemiology: 1,187 (rank: 13,547 (tie) )
    • evolutionary biology: 1,891 (rank: 4,763 (tie) )
    • genomics: 1,773 (rank: 17,743 (tie) )
    • hiv aids: 580 (rank: 578 (tie) )
    • microbiology: 1,849 (rank: 12,450 (tie) )
    • oncology: 3,193 (rank: 101 (tie) )
    • systems biology: 803 (rank: 8,052 (tie) )

Downloads per author, site-wide

Preprints

Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell Genomics

cancer biology more details view paper
  • Downloaded 3,384 times
  • Download rankings, all-time:
    • Site-wide: 5,955
    • In cancer biology: 80
  • Year to date:
    • Site-wide: 71,319
  • Since beginning of last month:
    • Site-wide: 137,419

The Tumor Profiler Study: Integrated, multi-omic, functional tumor profiling for clinical decision support

oncology more details view paper
  • Downloaded 3,285 times
  • Download rankings, all-time:
    • Site-wide: 6,231
    • In oncology: 6
  • Year to date:
    • Site-wide: 25,417
  • Since beginning of last month:
    • Site-wide: 21,680

Spatial structure governs the mode of tumour evolution

cancer biology more details view paper
  • Downloaded 2,309 times
  • Download rankings, all-time:
    • Site-wide: 10,460
    • In cancer biology: 175
  • Year to date:
    • Site-wide: 90,798
  • Since beginning of last month:
    • Site-wide: 88,713

ModulOmics: Integrating Multi-Omics Data to Identify Cancer Driver Modules

cancer biology more details view paper
  • Downloaded 2,272 times
  • Download rankings, all-time:
    • Site-wide: 10,716
    • In cancer biology: 182
  • Year to date:
    • Site-wide: 98,385
  • Since beginning of last month:
    • Site-wide: 54,245

High-dimensional microbiome interactions shape host fitness

microbiology more details view paper
  • Downloaded 1,872 times
  • Download rankings, all-time:
    • Site-wide: 14,357
    • In microbiology: 817
  • Year to date:
    • Site-wide: 126,208
  • Since beginning of last month:
    • Site-wide: 121,809

Single-cell copy number calling and event history reconstruction

cancer biology more details view paper
  • Downloaded 1,866 times
  • Download rankings, all-time:
    • Site-wide: 14,417
    • In cancer biology: 307
  • Year to date:
    • Site-wide: 17,238
  • Since beginning of last month:
    • Site-wide: 12,630

Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data

bioinformatics more details view paper
  • Downloaded 1,333 times
  • Download rankings, all-time:
    • Site-wide: 24,467
    • In bioinformatics: 2,580
  • Year to date:
    • Site-wide: 187,703
  • Since beginning of last month:
    • Site-wide: 108,130

Context-dependent deposition and regulation of mRNAs in P-bodies

cell biology more details view paper
  • Downloaded 1,266 times
  • Download rankings, all-time:
    • Site-wide: 26,604
    • In cell biology: 880
  • Year to date:
    • Site-wide: 183,623
  • Since beginning of last month:
    • Site-wide: 122,211

V-pipe: a computational pipeline for assessing viral genetic diversity from high-throughput sequencing data

bioinformatics more details view paper
  • Downloaded 1,252 times
  • Download rankings, all-time:
    • Site-wide: 27,074
    • In bioinformatics: 2,833
  • Year to date:
    • Site-wide: 94,661
  • Since beginning of last month:
    • Site-wide: None

Quantifying SARS-CoV-2 spread in Switzerland based on genomic sequencing data

epidemiology more details view paper
  • Downloaded 1,223 times
  • Download rankings, all-time:
    • Site-wide: 28,060
    • In epidemiology: 1,623
  • Year to date:
    • Site-wide: 76,535
  • Since beginning of last month:
    • Site-wide: 156,855

Within-patient genetic diversity of SARS-CoV-2

genomics more details view paper
  • Downloaded 1,178 times
  • Download rankings, all-time:
    • Site-wide: 29,749
    • In genomics: 2,549
  • Year to date:
    • Site-wide: 83,712
  • Since beginning of last month:
    • Site-wide: 27,324

A statistical test on single-cell data reveals widespread recurrent mutations in tumor evolution

cancer biology more details view paper
  • Downloaded 1,164 times
  • Download rankings, all-time:
    • Site-wide: 30,318
    • In cancer biology: 751
  • Year to date:
    • Site-wide: 193,332
  • Since beginning of last month:
    • Site-wide: 110,048

SCIΦ: Single-cell mutation identification via phylogenetic inference

bioinformatics more details view paper
  • Downloaded 1,151 times
  • Download rankings, all-time:
    • Site-wide: 30,862
    • In bioinformatics: 3,222
  • Year to date:
    • Site-wide: 130,995
  • Since beginning of last month:
    • Site-wide: 91,349

Bayesian non-parametric clustering of single-cell mutation profiles

bioinformatics more details view paper
  • Downloaded 1,080 times
  • Download rankings, all-time:
    • Site-wide: 34,027
    • In bioinformatics: 3,440
  • Year to date:
    • Site-wide: 170,093
  • Since beginning of last month:
    • Site-wide: None

Inferring Genetic Interactions From Comparative Fitness Data

evolutionary biology more details view paper
  • Downloaded 900 times
  • Download rankings, all-time:
    • Site-wide: 45,004
    • In evolutionary biology: 1,830
  • Year to date:
    • Site-wide: 120,272
  • Since beginning of last month:
    • Site-wide: 44,353

Mutational interactions define novel cancer subgroups

cancer biology more details view paper
  • Downloaded 860 times
  • Download rankings, all-time:
    • Site-wide: 48,260
    • In cancer biology: 1,315
  • Year to date:
    • Site-wide: 163,131
  • Since beginning of last month:
    • Site-wide: 129,729

Single cell network analysis with a mixture of Nested Effects Models

systems biology more details view paper
  • Downloaded 817 times
  • Download rankings, all-time:
    • Site-wide: 52,141
    • In systems biology: 999
  • Year to date:
    • Site-wide: 199,220
  • Since beginning of last month:
    • Site-wide: 185,699

Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens

bioinformatics more details view paper
  • Downloaded 812 times
  • Download rankings, all-time:
    • Site-wide: 52,571
    • In bioinformatics: 5,245
  • Year to date:
    • Site-wide: 72,770
  • Since beginning of last month:
    • Site-wide: 52,406

GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers

cancer biology more details view paper
  • Downloaded 808 times
  • Download rankings, all-time:
    • Site-wide: 52,972
    • In cancer biology: 1,485
  • Year to date:
    • Site-wide: 69,742
  • Since beginning of last month:
    • Site-wide: 74,766

Structured hierarchical models for probabilistic inference from perturbation screening data

bioinformatics more details view paper
  • Downloaded 795 times
  • Download rankings, all-time:
    • Site-wide: 54,272
    • In bioinformatics: 5,397
  • Year to date:
    • Site-wide: 80,794
  • Since beginning of last month:
    • Site-wide: 46,892

Tree inference for single-cell data

cancer biology more details view paper
  • Downloaded 776 times
  • Download rankings, all-time:
    • Site-wide: 56,182
    • In cancer biology: 1,563
  • Year to date:
    • Site-wide: 186,541
  • Since beginning of last month:
    • Site-wide: 149,677

scAmpi - A versatile pipeline for single-cell RNA-seq analysis from basics to clinics

bioinformatics more details view paper
  • Downloaded 706 times
  • Download rankings, all-time:
    • Site-wide: 64,474
    • In bioinformatics: 6,002
  • Year to date:
    • Site-wide: 38,363
  • Since beginning of last month:
    • Site-wide: 133,822

Systematic Identification of Novel Cancer Genes through Analysis of Deep shRNA Perturbation Screens

genomics more details view paper
  • Downloaded 672 times
  • Download rankings, all-time:
    • Site-wide: 69,097
    • In genomics: 4,584
  • Year to date:
    • Site-wide: 127,597
  • Since beginning of last month:
    • Site-wide: 85,869

Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment

hiv aids more details view paper
  • Downloaded 602 times
  • Download rankings, all-time:
    • Site-wide: 79,840
    • In hiv aids: 49
  • Year to date:
    • Site-wide: 132,478
  • Since beginning of last month:
    • Site-wide: 160,777

The geometry of partial fitness orders and an efficient method for detecting genetic interactions

evolutionary biology more details view paper
  • Downloaded 591 times
  • Download rankings, all-time:
    • Site-wide: 81,728
    • In evolutionary biology: 3,785
  • Year to date:
    • Site-wide: 148,103
  • Since beginning of last month:
    • Site-wide: 92,733

Latent epistatic interaction model identifies loci associated with human working memory

bioinformatics more details view paper
  • Downloaded 472 times
  • Download rankings, all-time:
    • Site-wide: 106,431
    • In bioinformatics: 8,756
  • Year to date:
    • Site-wide: 207,775
  • Since beginning of last month:
    • Site-wide: 203,414

scROSHI - robust supervised hierarchical identification of single cells

bioinformatics more details view paper
  • Downloaded 438 times
  • Download rankings, all-time:
    • Site-wide: 114,702
    • In bioinformatics: 10,554
  • Year to date:
    • Site-wide: 13,257
  • Since beginning of last month:
    • Site-wide: 32,314

A stochastic model of metastatic bottleneck predicts patient outcome and therapy response

cancer biology more details view paper
  • Downloaded 419 times
  • Download rankings, all-time:
    • Site-wide: 119,481
    • In cancer biology: 3,455
  • Year to date:
    • Site-wide: 196,173
  • Since beginning of last month:
    • Site-wide: 168,765

The Bourque Distances for Mutation Trees of Cancers

bioinformatics more details view paper
  • Downloaded 401 times
  • Download rankings, all-time:
    • Site-wide: 124,440
    • In bioinformatics: 9,808
  • Year to date:
    • Site-wide: 208,234
  • Since beginning of last month:
    • Site-wide: None

Improved pathway reconstruction from RNA interference screens by exploiting off-target effects

bioinformatics more details view paper
  • Downloaded 355 times
  • Download rankings, all-time:
    • Site-wide: 137,777
    • In bioinformatics: 10,542
  • Year to date:
    • Site-wide: 208,901
  • Since beginning of last month:
    • Site-wide: 205,289

Drug-induced resistance evolution necessitates less aggressive treatment

evolutionary biology more details view paper
  • Downloaded 306 times
  • Download rankings, all-time:
    • Site-wide: 152,339
    • In evolutionary biology: 6,784
  • Year to date:
    • Site-wide: 205,669
  • Since beginning of last month:
    • Site-wide: 194,051

Inferring perturbation profiles of cancer samples

bioinformatics more details view paper
  • Downloaded 276 times
  • Download rankings, all-time:
    • Site-wide: 161,166
    • In bioinformatics: 12,076
  • Year to date:
    • Site-wide: 195,271
  • Since beginning of last month:
    • Site-wide: 189,410

Learning epistatic gene interactions from perturbation screens

bioinformatics more details view paper
  • Downloaded 273 times
  • Download rankings, all-time:
    • Site-wide: 162,162
    • In bioinformatics: 12,038
  • Year to date:
    • Site-wide: 201,516
  • Since beginning of last month:
    • Site-wide: 194,257

Dynamic changes of genomic and transcriptomic tumor diversity during melanoma progression

cancer biology more details view paper
  • Downloaded 245 times
  • Download rankings, all-time:
    • Site-wide: 170,082
    • In cancer biology: 5,148
  • Year to date:
    • Site-wide: 115,742
  • Since beginning of last month:
    • Site-wide: 83,450

Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C

evolutionary biology more details view paper
  • Downloaded 184 times
  • Download rankings, all-time:
    • Site-wide: 185,318
    • In evolutionary biology: 8,096
  • Year to date:
    • Site-wide: 184,317
  • Since beginning of last month:
    • Site-wide: 193,806

gExcite - A start-to-end framework for single-cell gene expression, hashing, and antibody analysis

bioinformatics more details view paper
  • Downloaded 167 times
  • Download rankings, all-time:
    • Site-wide: 188,787
    • In bioinformatics: 13,831
  • Year to date:
    • Site-wide: 56,565
  • Since beginning of last month:
    • Site-wide: 51,458

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