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Author: Mathew J Garnett

Rankings

  • All-time downloads: 32,334 (rank: 5,505 )
  • Categories:
    • bioinformatics: 10,801 (rank: 770 )
    • cancer biology: 13,826 (rank: 132 )
    • genomics: 3,107 (rank: 8,247 (tie) )
    • systems biology: 4,600 (rank: 768 )

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Preprints

Prioritisation of oncology therapeutic targets using CRISPR-Cas9 screening

cancer biology more details view paper
  • Downloaded 4,546 times
  • Download rankings, all-time:
    • Site-wide: 2,650
    • In cancer biology: 33
  • Year to date:
    • Site-wide: 6,463
  • Since beginning of last month:
    • Site-wide: 5,373

A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction

bioinformatics more details view paper
  • Downloaded 4,190 times
  • Download rankings, all-time:
    • Site-wide: 2,977
    • In bioinformatics: 250
  • Year to date:
    • Site-wide: 49,200
  • Since beginning of last month:
    • Site-wide: 42,162

Minimal genome-wide human CRISPR-Cas9 library

genomics more details view paper
  • Downloaded 2,264 times
  • Download rankings, all-time:
    • Site-wide: 7,190
    • In genomics: 762
  • Year to date:
    • Site-wide: 17,876
  • Since beginning of last month:
    • Site-wide: 22,251

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

systems biology more details view paper
  • Downloaded 2,083 times
  • Download rankings, all-time:
    • Site-wide: 8,096
    • In systems biology: 137
  • Year to date:
    • Site-wide: 42,244
  • Since beginning of last month:
    • Site-wide: 96,598

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

cancer biology more details view paper
  • Downloaded 2,039 times
  • Download rankings, all-time:
    • Site-wide: 8,341
    • In cancer biology: 140
  • Year to date:
    • Site-wide: 88,876
  • Since beginning of last month:
    • Site-wide: 84,902

Integrated cross-study datasets of genetic dependencies in cancer

bioinformatics more details view paper
  • Downloaded 2,005 times
  • Download rankings, all-time:
    • Site-wide: 8,590
    • In bioinformatics: 989
  • Year to date:
    • Site-wide: 2,617
  • Since beginning of last month:
    • Site-wide: 9,795

Transcription factor activities enhance markers of drug response in cancer

cancer biology more details view paper
  • Downloaded 2,003 times
  • Download rankings, all-time:
    • Site-wide: 8,598
    • In cancer biology: 145
  • Year to date:
    • Site-wide: 78,722
  • Since beginning of last month:
    • Site-wide: 80,512

CELLector: Genomics Guided Selection of Cancer in vitro Models

bioinformatics more details view paper
  • Downloaded 1,981 times
  • Download rankings, all-time:
    • Site-wide: 8,761
    • In bioinformatics: 1,018
  • Year to date:
    • Site-wide: 85,860
  • Since beginning of last month:
    • Site-wide: 144,586

Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells

systems biology more details view paper
  • Downloaded 1,800 times
  • Download rankings, all-time:
    • Site-wide: 10,091
    • In systems biology: 183
  • Year to date:
    • Site-wide: 65,696
  • Since beginning of last month:
    • Site-wide: 53,528

Perturbation-response genes reveal signaling footprints in cancer gene expression

bioinformatics more details view paper
  • Downloaded 1,596 times
  • Download rankings, all-time:
    • Site-wide: 12,041
    • In bioinformatics: 1,398
  • Year to date:
    • Site-wide: 64,772
  • Since beginning of last month:
    • Site-wide: 48,716

Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR/Cas9 screening

cancer biology more details view paper
  • Downloaded 1,149 times
  • Download rankings, all-time:
    • Site-wide: 19,643
    • In cancer biology: 456
  • Year to date:
    • Site-wide: 105,393
  • Since beginning of last month:
    • Site-wide: 143,561

A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination

cancer biology more details view paper
  • Downloaded 891 times
  • Download rankings, all-time:
    • Site-wide: 28,420
    • In cancer biology: 726
  • Year to date:
    • Site-wide: 63,802
  • Since beginning of last month:
    • Site-wide: 62,028

GDSCTools for Mining Pharmacogenomic Interactions in Cancer

cancer biology more details view paper
  • Downloaded 881 times
  • Download rankings, all-time:
    • Site-wide: 28,904
    • In cancer biology: 739
  • Year to date:
    • Site-wide: 62,981
  • Since beginning of last month:
    • Site-wide: 62,198

Tandem duplications lead to loss of fitness effects in CRISPR-Cas9 data

genomics more details view paper
  • Downloaded 843 times
  • Download rankings, all-time:
    • Site-wide: 30,697
    • In genomics: 2,720
  • Year to date:
    • Site-wide: 104,317
  • Since beginning of last month:
    • Site-wide: 106,228

Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

bioinformatics more details view paper
  • Downloaded 747 times
  • Download rankings, all-time:
    • Site-wide: 36,327
    • In bioinformatics: 3,966
  • Year to date:
    • Site-wide: 140,088
  • Since beginning of last month:
    • Site-wide: 106,881

Patient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

systems biology more details view paper
  • Downloaded 717 times
  • Download rankings, all-time:
    • Site-wide: 38,452
    • In systems biology: 844
  • Year to date:
    • Site-wide: 138,604
  • Since beginning of last month:
    • Site-wide: 105,943

Dissecting cancer resistance to therapies with cell-type-specific dynamic logic models

cancer biology more details view paper
  • Downloaded 595 times
  • Download rankings, all-time:
    • Site-wide: 48,815
    • In cancer biology: 1,381
  • Year to date:
    • Site-wide: 131,452
  • Since beginning of last month:
    • Site-wide: 93,239

N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers

cancer biology more details view paper
  • Downloaded 585 times
  • Download rankings, all-time:
    • Site-wide: 49,905
    • In cancer biology: 1,406
  • Year to date:
    • Site-wide: 6,346
  • Since beginning of last month:
    • Site-wide: 14,251

A statistical framework for assessing pharmacological response and biomarkers using uncertainty estimates

cancer biology more details view paper
  • Downloaded 573 times
  • Download rankings, all-time:
    • Site-wide: 51,313
    • In cancer biology: 1,439
  • Year to date:
    • Site-wide: 72,271
  • Since beginning of last month:
    • Site-wide: 127,062

A landscape of synergistic drug combinations in non-small-cell lung cancer

cancer biology more details view paper
  • Downloaded 564 times
  • Download rankings, all-time:
    • Site-wide: 52,261
    • In cancer biology: 1,472
  • Year to date:
    • Site-wide: 6,692
  • Since beginning of last month:
    • Site-wide: 12,925

CoRe: A robustly benchmarked R package for the identification of core fitness genes in genome-wide pooled CRISPR knock-out screens

bioinformatics more details view paper
  • Downloaded 282 times
  • Download rankings, all-time:
    • Site-wide: 100,422
    • In bioinformatics: 8,635
  • Year to date:
    • Site-wide: 18,070
  • Since beginning of last month:
    • Site-wide: 22,513

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