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Author: Mathew J Garnett

Rankings

  • All-time downloads: 42,006 (rank: 5,798 )
  • Categories:
    • bioinformatics: 11,898 (rank: 853 )
    • cancer biology: 16,171 (rank: 105 )
    • genomics: 3,322 (rank: 8,771 (tie) )
    • systems biology: 4,862 (rank: 920 )

Downloads per author, site-wide

Preprints

Prioritisation of oncology therapeutic targets using CRISPR-Cas9 screening

cancer biology more details view paper
  • Downloaded 5,634 times
  • Download rankings, all-time:
    • Site-wide: 2,691
    • In cancer biology: 32
  • Year to date:
    • Site-wide: 3,854
  • Since beginning of last month:
    • Site-wide: 4,664

A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction

bioinformatics more details view paper
  • Downloaded 4,360 times
  • Download rankings, all-time:
    • Site-wide: 3,796
    • In bioinformatics: 291
  • Year to date:
    • Site-wide: 78,422
  • Since beginning of last month:
    • Site-wide: 85,750

Pan-cancer proteomic map of 949 human cell lines reveals principles of cancer vulnerabilities

systems biology more details view paper
  • Downloaded 3,536 times
  • Download rankings, all-time:
    • Site-wide: 5,121
    • In systems biology: None
  • Year to date:
    • Site-wide: 301
  • Since beginning of last month:
    • Site-wide: 1,966

Integrated cross-study datasets of genetic dependencies in cancer

bioinformatics more details view paper
  • Downloaded 2,553 times
  • Download rankings, all-time:
    • Site-wide: 8,272
    • In bioinformatics: 818
  • Year to date:
    • Site-wide: 27,292
  • Since beginning of last month:
    • Site-wide: 33,497

Minimal genome-wide human CRISPR-Cas9 library

genomics more details view paper
  • Downloaded 2,467 times
  • Download rankings, all-time:
    • Site-wide: 8,675
    • In genomics: 813
  • Year to date:
    • Site-wide: 66,769
  • Since beginning of last month:
    • Site-wide: 46,914

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

systems biology more details view paper
  • Downloaded 2,250 times
  • Download rankings, all-time:
    • Site-wide: 9,910
    • In systems biology: 144
  • Year to date:
    • Site-wide: 78,291
  • Since beginning of last month:
    • Site-wide: 54,730

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

cancer biology more details view paper
  • Downloaded 2,118 times
  • Download rankings, all-time:
    • Site-wide: 10,895
    • In cancer biology: 172
  • Year to date:
    • Site-wide: 106,872
  • Since beginning of last month:
    • Site-wide: 144,888

CELLector: Genomics Guided Selection of Cancer in vitro Models

bioinformatics more details view paper
  • Downloaded 2,077 times
  • Download rankings, all-time:
    • Site-wide: 11,230
    • In bioinformatics: 1,143
  • Year to date:
    • Site-wide: 96,443
  • Since beginning of last month:
    • Site-wide: 131,367

Transcription factor activities enhance markers of drug response in cancer

cancer biology more details view paper
  • Downloaded 2,049 times
  • Download rankings, all-time:
    • Site-wide: 11,468
    • In cancer biology: 192
  • Year to date:
    • Site-wide: 164,943
  • Since beginning of last month:
    • Site-wide: 142,672

Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells

systems biology more details view paper
  • Downloaded 1,948 times
  • Download rankings, all-time:
    • Site-wide: 12,348
    • In systems biology: 195
  • Year to date:
    • Site-wide: 70,978
  • Since beginning of last month:
    • Site-wide: 44,113

Perturbation-response genes reveal signaling footprints in cancer gene expression

bioinformatics more details view paper
  • Downloaded 1,687 times
  • Download rankings, all-time:
    • Site-wide: 15,245
    • In bioinformatics: 1,539
  • Year to date:
    • Site-wide: 107,454
  • Since beginning of last month:
    • Site-wide: 150,320

Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR/Cas9 screening

cancer biology more details view paper
  • Downloaded 1,214 times
  • Download rankings, all-time:
    • Site-wide: 25,387
    • In cancer biology: 572
  • Year to date:
    • Site-wide: 156,545
  • Since beginning of last month:
    • Site-wide: 114,015

N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers

cancer biology more details view paper
  • Downloaded 1,119 times
  • Download rankings, all-time:
    • Site-wide: 28,741
    • In cancer biology: 902
  • Year to date:
    • Site-wide: 14,271
  • Since beginning of last month:
    • Site-wide: 6,693

A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination

cancer biology more details view paper
  • Downloaded 1,031 times
  • Download rankings, all-time:
    • Site-wide: 32,493
    • In cancer biology: 821
  • Year to date:
    • Site-wide: 76,893
  • Since beginning of last month:
    • Site-wide: 58,799

GDSCTools for Mining Pharmacogenomic Interactions in Cancer

cancer biology more details view paper
  • Downloaded 978 times
  • Download rankings, all-time:
    • Site-wide: 35,137
    • In cancer biology: 878
  • Year to date:
    • Site-wide: 96,351
  • Since beginning of last month:
    • Site-wide: 86,243

A landscape of synergistic drug combinations in non-small-cell lung cancer

cancer biology more details view paper
  • Downloaded 946 times
  • Download rankings, all-time:
    • Site-wide: 36,932
    • In cancer biology: 1,118
  • Year to date:
    • Site-wide: 19,552
  • Since beginning of last month:
    • Site-wide: 29,193

Tandem duplications lead to loss of fitness effects in CRISPR-Cas9 data

genomics more details view paper
  • Downloaded 929 times
  • Download rankings, all-time:
    • Site-wide: 38,012
    • In genomics: 2,895
  • Year to date:
    • Site-wide: 133,683
  • Since beginning of last month:
    • Site-wide: 141,105

Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

bioinformatics more details view paper
  • Downloaded 792 times
  • Download rankings, all-time:
    • Site-wide: 48,071
    • In bioinformatics: 4,551
  • Year to date:
    • Site-wide: 179,463
  • Since beginning of last month:
    • Site-wide: 170,998

Base editing screens map mutations affecting IFNγ signalling in cancer

cancer biology more details view paper
  • Downloaded 791 times
  • Download rankings, all-time:
    • Site-wide: 48,187
    • In cancer biology: None
  • Year to date:
    • Site-wide: 2,485
  • Since beginning of last month:
    • Site-wide: 3,320

Patient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

systems biology more details view paper
  • Downloaded 771 times
  • Download rankings, all-time:
    • Site-wide: 49,991
    • In systems biology: 954
  • Year to date:
    • Site-wide: 169,149
  • Since beginning of last month:
    • Site-wide: 184,450

A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

cancer biology more details view paper
  • Downloaded 745 times
  • Download rankings, all-time:
    • Site-wide: 52,426
    • In cancer biology: 1,735
  • Year to date:
    • Site-wide: 20,383
  • Since beginning of last month:
    • Site-wide: 49,738

CoRe: A robustly benchmarked R package for the identification of core fitness genes in genome-wide pooled CRISPR knock-out screens

bioinformatics more details view paper
  • Downloaded 693 times
  • Download rankings, all-time:
    • Site-wide: 58,067
    • In bioinformatics: 5,946
  • Year to date:
    • Site-wide: 36,513
  • Since beginning of last month:
    • Site-wide: 55,495

A statistical framework for assessing pharmacological response and biomarkers using uncertainty estimates

cancer biology more details view paper
  • Downloaded 690 times
  • Download rankings, all-time:
    • Site-wide: 58,315
    • In cancer biology: 1,621
  • Year to date:
    • Site-wide: 89,369
  • Since beginning of last month:
    • Site-wide: 67,743

Dissecting cancer resistance to therapies with cell-type-specific dynamic logic models

cancer biology more details view paper
  • Downloaded 628 times
  • Download rankings, all-time:
    • Site-wide: 66,270
    • In cancer biology: 1,751
  • Year to date:
    • Site-wide: 182,915
  • Since beginning of last month:
    • Site-wide: 174,820

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