Author: Gail Davies

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 875
  • In genetics: 26
• Year to date:
  • Site-wide: 32,750
• Since beginning of last month:
  • Site-wide: 37,308

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

• Downloaded 5,219 times
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  • Site-wide: 1,878
  • In genetics: 68
• Year to date:
  • Site-wide: 19,542
• Since beginning of last month:
  • Site-wide: 17,569

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

• Downloaded 4,537 times
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  • Site-wide: 2,295
  • In genetics: 85
• Year to date:
  • Site-wide: 32,695
• Since beginning of last month:
  • Site-wide: 32,738

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,261 times
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  • Site-wide: 3,708
  • In genetics: 152
• Year to date:
  • Site-wide: 43,073
• Since beginning of last month:
  • Site-wide: 89,135

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 3,083 times
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  • Site-wide: 4,004
  • In genetics: 168
• Year to date:
  • Site-wide: 55,879
• Since beginning of last month:
  • Site-wide: 75,377

Genetic analysis identifies molecular systems and biological pathways associated with household income

• Downloaded 2,710 times
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  • Site-wide: 4,820
  • In genetics: 213
• Year to date:
  • Site-wide: 100,288
• Since beginning of last month:
  • Site-wide: 108,485

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

• Downloaded 2,582 times
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  • Site-wide: 5,142
  • In genetics: 232
• Year to date:
  • Site-wide: 64,573
• Since beginning of last month:
  • Site-wide: 55,414

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 2,567 times
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  • Site-wide: 5,193
  • In genetics: 237
• Year to date:
  • Site-wide: 23,664
• Since beginning of last month:
  • Site-wide: 29,943

Molecular genetic contributions to self-rated health

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  • Site-wide: 6,392
  • In genetics: 307
• Year to date:
  • Site-wide: 57,896
• Since beginning of last month:
  • Site-wide: 48,144

Genetic “General Intelligence,” Objectively Determined and Measured

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  • Site-wide: 6,650
  • In genetics: 320
• Year to date:
  • Site-wide: 14,644
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  • Site-wide: 21,821

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

• Downloaded 2,039 times
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  • Site-wide: 7,289
  • In genetics: 344
• Year to date:
  • Site-wide: 114,816
• Since beginning of last month:
  • Site-wide: 116,278

GWAS on family history of Alzheimer's disease

• Downloaded 1,990 times
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  • Site-wide: 7,580
  • In genetics: 353
• Year to date:
  • Site-wide: 65,170
• Since beginning of last month:
  • Site-wide: 54,106

Genetic Prediction of Male Pattern Baldness

• Downloaded 1,792 times
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  • Site-wide: 8,864
  • In genetics: 415
• Year to date:
  • Site-wide: 64,390
• Since beginning of last month:
  • Site-wide: 85,876

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,713 times
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  • Site-wide: 9,507
  • In genetics: 453
• Year to date:
  • Site-wide: 78,667
• Since beginning of last month:
  • Site-wide: 85,473

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

• Downloaded 1,702 times
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  • Site-wide: 9,608
  • In genetics: 457
• Year to date:
  • Site-wide: 57,850
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  • Site-wide: 58,004

Age differences in brain white matter microstructure in UK Biobank (N = 3,513)

• Downloaded 1,640 times
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  • Site-wide: 10,115
  • In neuroscience: 1,099
• Year to date:
  • Site-wide: 81,394
• Since beginning of last month:
  • Site-wide: 88,841

Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)

• Downloaded 1,620 times
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  • Site-wide: 10,289
  • In genetics: 495
• Year to date:
  • Site-wide: 87,312
• Since beginning of last month:
  • Site-wide: 101,756

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

• Downloaded 1,368 times
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  • Site-wide: 13,251
  • In genetics: 648
• Year to date:
  • Site-wide: 69,009
• Since beginning of last month:
  • Site-wide: 50,853

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

• Downloaded 1,206 times
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  • Site-wide: 16,014
  • In genetics: 790
• Year to date:
  • Site-wide: 5,625
• Since beginning of last month:
  • Site-wide: 5,004

Genome wide analysis of gene dosage in 24,092 individuals shows that 10,000 genes modulate cognitive ability

• Downloaded 1,033 times
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  • Site-wide: 20,124
  • In genetics: 966
• Year to date:
  • Site-wide: 17,260
• Since beginning of last month:
  • Site-wide: 42,139

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 877 times
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  • Site-wide: 25,528
  • In genetics: 1,229
• Year to date:
  • Site-wide: 20,712
• Since beginning of last month:
  • Site-wide: 12,997

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

• Downloaded 757 times
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  • Site-wide: 31,350
  • In genetics: 1,506
• Year to date:
  • Site-wide: 115,908
• Since beginning of last month:
  • Site-wide: 127,170

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 752 times
• Download rankings, all-time:
  • Site-wide: 31,634
  • In genomics: 2,819
• Year to date:
  • Site-wide: 94,590
• Since beginning of last month:
  • Site-wide: 108,192

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

• Downloaded 745 times
• Download rankings, all-time:
  • Site-wide: 32,033
  • In genetics: 1,548
• Year to date:
  • Site-wide: 108,115
• Since beginning of last month:
  • Site-wide: 128,936

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

• Downloaded 727 times
• Download rankings, all-time:
  • Site-wide: 33,157
  • In genetics: 1,601
• Year to date:
  • Site-wide: 125,256
• Since beginning of last month:
  • Site-wide: 124,873

Genetic contributions to self-reported tiredness

• Downloaded 714 times
• Download rankings, all-time:
  • Site-wide: 33,917
  • In genetics: 1,634
• Year to date:
  • Site-wide: 60,682
• Since beginning of last month:
  • Site-wide: 128,833

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

• Downloaded 704 times
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  • Site-wide: 34,620
  • In genomics: 3,011
• Year to date:
  • Site-wide: 130,619
• Since beginning of last month:
  • Site-wide: 125,189

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

• Downloaded 678 times
• Download rankings, all-time:
  • Site-wide: 36,440
  • In genetics: 1,730
• Year to date:
  • Site-wide: 73,157
• Since beginning of last month:
  • Site-wide: 55,008

Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK Biobank

• Downloaded 571 times
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  • Site-wide: 45,245
  • In genetics: 2,129
• Year to date:
  • Site-wide: 106,117
• Since beginning of last month:
  • Site-wide: 101,765

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

• Downloaded 513 times
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  • Site-wide: 51,474
  • In genomics: 4,012
• Year to date:
  • Site-wide: 71,849
• Since beginning of last month:
  • Site-wide: 65,520

Polygenic predictors of age-related decline in cognitive ability

• Downloaded 484 times
• Download rankings, all-time:
  • Site-wide: 55,077
  • In genomics: 4,191
• Year to date:
  • Site-wide: 124,607
• Since beginning of last month:
  • Site-wide: 123,452

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 476 times
• Download rankings, all-time:
  • Site-wide: 56,099
  • In genetics: 2,598
• Year to date:
  • Site-wide: 119,259
• Since beginning of last month:
  • Site-wide: 132,739

Genetic contributions to trail making test performance in UK Biobank

• Downloaded 468 times
• Download rankings, all-time:
  • Site-wide: 57,176
  • In genetics: 2,664
• Year to date:
  • Site-wide: 102,847
• Since beginning of last month:
  • Site-wide: 72,111

The influence of X chromosome variants on trait neuroticism.

• Downloaded 382 times
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  • Site-wide: 70,058
  • In genetics: 3,198
• Year to date:
  • Site-wide: 105,422
• Since beginning of last month:
  • Site-wide: 85,597

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

• Downloaded 349 times
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  • Site-wide: 75,888
  • In genetics: 3,461
• Year to date:
  • Site-wide: 122,820
• Since beginning of last month:
  • Site-wide: 113,603

Genetic contributions to health literacy

• Downloaded 337 times
• Download rankings, all-time:
  • Site-wide: 78,273
  • In epidemiology: 3,262
• Year to date:
  • Site-wide: 126,899
• Since beginning of last month:
  • Site-wide: 132,276