Author: Gail Davies

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 754
  • In genetics: 24
• Year to date:
  • Site-wide: 21,710
• Since beginning of last month:
  • Site-wide: 23,223

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

• Downloaded 5,110 times
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  • Site-wide: 1,676
  • In genetics: 67
• Year to date:
  • Site-wide: 10,973
• Since beginning of last month:
  • Site-wide: 19,000

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

• Downloaded 4,463 times
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  • Site-wide: 2,032
  • In genetics: 82
• Year to date:
  • Site-wide: 30,565
• Since beginning of last month:
  • Site-wide: 13,607

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,210 times
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  • Site-wide: 3,297
  • In genetics: 146
• Year to date:
  • Site-wide: 26,063
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  • Site-wide: 43,947

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 3,052 times
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  • Site-wide: 3,553
  • In genetics: 163
• Year to date:
  • Site-wide: 19,361
• Since beginning of last month:
  • Site-wide: 42,060

Genetic analysis identifies molecular systems and biological pathways associated with household income

• Downloaded 2,689 times
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  • Site-wide: 4,212
  • In genetics: 202
• Year to date:
  • Site-wide: 121,930
• Since beginning of last month:
  • Site-wide: 24,519

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

• Downloaded 2,544 times
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  • Site-wide: 4,591
  • In genetics: 222
• Year to date:
  • Site-wide: 103,136
• Since beginning of last month:
  • Site-wide: 68,871

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 2,476 times
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  • Site-wide: 4,778
  • In genetics: 233
• Year to date:
  • Site-wide: 12,450
• Since beginning of last month:
  • Site-wide: 15,667

Molecular genetic contributions to self-rated health

• Downloaded 2,191 times
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  • Site-wide: 5,740
  • In genetics: 286
• Year to date:
  • Site-wide: 101,630
• Since beginning of last month:
  • Site-wide: 42,290

Genetic “General Intelligence,” Objectively Determined and Measured

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  • Site-wide: 6,388
  • In genetics: 324
• Year to date:
  • Site-wide: 9,370
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  • Site-wide: 25,473

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

• Downloaded 2,024 times
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  • Site-wide: 6,431
  • In genetics: 327
• Year to date:
  • Site-wide: 115,994
• Since beginning of last month:
  • Site-wide: 80,687

GWAS on family history of Alzheimer's disease

• Downloaded 1,953 times
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  • Site-wide: 6,776
  • In genetics: 339
• Year to date:
  • Site-wide: 99,821
• Since beginning of last month:
  • Site-wide: 109,675

Genetic Prediction of Male Pattern Baldness

• Downloaded 1,758 times
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  • Site-wide: 7,903
  • In genetics: 396
• Year to date:
  • Site-wide: 57,302
• Since beginning of last month:
  • Site-wide: 80,879

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,684 times
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  • Site-wide: 8,477
  • In genetics: 432
• Year to date:
  • Site-wide: 104,914
• Since beginning of last month:
  • Site-wide: 64,040

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

• Downloaded 1,661 times
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  • Site-wide: 8,666
  • In genetics: 440
• Year to date:
  • Site-wide: 81,259
• Since beginning of last month:
  • Site-wide: 64,667

Age differences in brain white matter microstructure in UK Biobank (N = 3,513)

• Downloaded 1,617 times
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  • Site-wide: 9,036
  • In neuroscience: 998
• Year to date:
  • Site-wide: 56,166
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  • Site-wide: 59,717

Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)

• Downloaded 1,598 times
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  • Site-wide: 9,183
  • In genetics: 470
• Year to date:
  • Site-wide: 84,556
• Since beginning of last month:
  • Site-wide: 60,328

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

• Downloaded 1,334 times
• Download rankings, all-time:
  • Site-wide: 12,016
  • In genetics: 616
• Year to date:
  • Site-wide: 100,000
• Since beginning of last month:
  • Site-wide: 50,286

Genome wide analysis of gene dosage in 24,092 individuals shows that 10,000 genes modulate cognitive ability

• Downloaded 944 times
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  • Site-wide: 20,118
  • In genetics: 1,011
• Year to date:
  • Site-wide: 3,503
• Since beginning of last month:
  • Site-wide: 19,139

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

• Downloaded 908 times
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  • Site-wide: 21,323
  • In genetics: 1,069
• Year to date:
  • Site-wide: 5,935
• Since beginning of last month:
  • Site-wide: 12,530

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 764 times
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  • Site-wide: 27,227
  • In genetics: 1,372
• Year to date:
  • Site-wide: 21,384
• Since beginning of last month:
  • Site-wide: 24,317

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

• Downloaded 745 times
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  • Site-wide: 28,218
  • In genetics: 1,428
• Year to date:
  • Site-wide: 91,872
• Since beginning of last month:
  • Site-wide: 90,031

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 738 times
• Download rankings, all-time:
  • Site-wide: 28,596
  • In genomics: 2,655
• Year to date:
  • Site-wide: 39,396
• Since beginning of last month:
  • Site-wide: 110,738

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

• Downloaded 729 times
• Download rankings, all-time:
  • Site-wide: 29,070
  • In genetics: 1,462
• Year to date:
  • Site-wide: 103,089
• Since beginning of last month:
  • Site-wide: 93,300

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

• Downloaded 719 times
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  • Site-wide: 29,634
  • In genetics: 1,492
• Year to date:
  • Site-wide: 80,356
• Since beginning of last month:
  • Site-wide: 95,164

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

• Downloaded 696 times
• Download rankings, all-time:
  • Site-wide: 30,951
  • In genomics: 2,813
• Year to date:
  • Site-wide: 102,590
• Since beginning of last month:
  • Site-wide: 121,060

Genetic contributions to self-reported tiredness

• Downloaded 685 times
• Download rankings, all-time:
  • Site-wide: 31,631
  • In genetics: 1,594
• Year to date:
  • Site-wide: 23,765
• Since beginning of last month:
  • Site-wide: 64,698

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

• Downloaded 650 times
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  • Site-wide: 33,960
  • In genetics: 1,697
• Year to date:
  • Site-wide: 59,805
• Since beginning of last month:
  • Site-wide: 100,815

Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK Biobank

• Downloaded 557 times
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  • Site-wide: 41,296
  • In genetics: 2,024
• Year to date:
  • Site-wide: 67,397
• Since beginning of last month:
  • Site-wide: 111,468

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

• Downloaded 485 times
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  • Site-wide: 48,761
  • In genomics: 3,881
• Year to date:
  • Site-wide: 52,800
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  • Site-wide: 64,577

Polygenic predictors of age-related decline in cognitive ability

• Downloaded 477 times
• Download rankings, all-time:
  • Site-wide: 49,640
  • In genomics: 3,934
• Year to date:
  • Site-wide: 70,946
• Since beginning of last month:
  • Site-wide: 120,099

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 468 times
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  • Site-wide: 50,707
  • In genetics: 2,460
• Year to date:
  • Site-wide: 60,400
• Since beginning of last month:
  • Site-wide: 113,282

Genetic contributions to trail making test performance in UK Biobank

• Downloaded 450 times
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  • Site-wide: 52,910
  • In genetics: 2,554
• Year to date:
  • Site-wide: 102,305
• Since beginning of last month:
  • Site-wide: 87,648

The influence of X chromosome variants on trait neuroticism.

• Downloaded 367 times
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  • Site-wide: 64,949
  • In genetics: 3,093
• Year to date:
  • Site-wide: 82,506
• Since beginning of last month:
  • Site-wide: 81,193

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

• Downloaded 338 times
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  • Site-wide: 69,742
  • In genetics: 3,309
• Year to date:
  • Site-wide: 98,354
• Since beginning of last month:
  • Site-wide: 109,998

Genetic contributions to health literacy

• Downloaded 328 times
• Download rankings, all-time:
  • Site-wide: 71,598
  • In epidemiology: 2,932
• Year to date:
  • Site-wide: 109,587
• Since beginning of last month:
  • Site-wide: 116,955