Author: Gail Davies

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 1,150
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• Year to date:
  • Site-wide: 43,373
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  • Site-wide: 30,930

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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  • Site-wide: 2,364
  • In genetics: 70
• Year to date:
  • Site-wide: 23,022
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  • Site-wide: 33,376

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

• Downloaded 4,687 times
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  • Site-wide: 2,923
  • In genetics: 91
• Year to date:
  • Site-wide: 48,003
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  • Site-wide: 122,890

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,380 times
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  • Site-wide: 4,648
  • In genetics: 168
• Year to date:
  • Site-wide: 64,899
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  • Site-wide: 128,557

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 3,289 times
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  • Site-wide: 4,831
  • In genetics: 181
• Year to date:
  • Site-wide: 43,683
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  • Site-wide: 63,239

Genetic analysis identifies molecular systems and biological pathways associated with household income

• Downloaded 2,801 times
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  • Site-wide: 6,076
  • In genetics: 242
• Year to date:
  • Site-wide: 105,885
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  • Site-wide: 105,236

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 2,776 times
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  • Site-wide: 6,158
  • In genetics: 250
• Year to date:
  • Site-wide: 31,224
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  • Site-wide: 43,998

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

• Downloaded 2,666 times
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  • Site-wide: 6,525
  • In genetics: 262
• Year to date:
  • Site-wide: 96,994
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  • Site-wide: 133,505

Genetic “General Intelligence,” Objectively Determined and Measured

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  • Site-wide: 6,997
  • In genetics: 283
• Year to date:
  • Site-wide: 13,988
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  • Site-wide: 30,704

Molecular genetic contributions to self-rated health

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  • Site-wide: 8,205
  • In genetics: 348
• Year to date:
  • Site-wide: 115,952
• Since beginning of last month:
  • Site-wide: 137,365

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

• Downloaded 2,082 times
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  • Site-wide: 9,400
  • In genetics: 386
• Year to date:
  • Site-wide: 150,099
• Since beginning of last month:
  • Site-wide: 156,421

GWAS on family history of Alzheimer's disease

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  • Site-wide: 9,591
  • In genetics: 393
• Year to date:
  • Site-wide: 113,042
• Since beginning of last month:
  • Site-wide: 115,642

Genetic Prediction of Male Pattern Baldness

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  • Site-wide: 10,639
  • In genetics: 446
• Year to date:
  • Site-wide: 72,806
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  • Site-wide: 84,319

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

• Downloaded 1,828 times
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  • Site-wide: 11,448
  • In genetics: 482
• Year to date:
  • Site-wide: 70,116
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  • Site-wide: 94,139

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • Site-wide: 11,829
  • In genetics: 503
• Year to date:
  • Site-wide: 109,203
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  • Site-wide: 110,617

Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)

• Downloaded 1,725 times
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  • Site-wide: 12,478
  • In genetics: 535
• Year to date:
  • Site-wide: 91,871
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  • Site-wide: 106,062

Age differences in brain white matter microstructure in UK Biobank (N = 3,513)

• Downloaded 1,686 times
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  • Site-wide: 12,905
  • In neuroscience: 1,376
• Year to date:
  • Site-wide: 137,177
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  • Site-wide: 144,018

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

• Downloaded 1,576 times
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  • Site-wide: 14,267
  • In genetics: 622
• Year to date:
  • Site-wide: 45,759
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  • Site-wide: 30,929

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

• Downloaded 1,546 times
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  • Site-wide: 14,724
  • In genetics: 646
• Year to date:
  • Site-wide: 10,001
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  • Site-wide: 38,889

Genome wide analysis of gene dosage in 24,092 individuals shows that 10,000 genes modulate cognitive ability

• Downloaded 1,252 times
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  • Site-wide: 20,344
  • In genetics: 900
• Year to date:
  • Site-wide: 25,890
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  • Site-wide: 34,237

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • Site-wide: 25,554
  • In genetics: 1,121
• Year to date:
  • Site-wide: 30,207
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  • Site-wide: 65,273

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

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  • Site-wide: 39,595
  • In genetics: 1,712
• Year to date:
  • Site-wide: 150,951
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  • Site-wide: 146,441

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • Site-wide: 39,600
  • In genomics: 3,195
• Year to date:
  • Site-wide: 140,586
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  • Site-wide: 146,740

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

• Downloaded 774 times
• Download rankings, all-time:
  • Site-wide: 41,551
  • In genetics: 1,790
• Year to date:
  • Site-wide: 157,090
• Since beginning of last month:
  • Site-wide: 154,481

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

• Downloaded 771 times
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  • Site-wide: 41,818
  • In genetics: 1,801
• Year to date:
  • Site-wide: 94,889
• Since beginning of last month:
  • Site-wide: 104,267

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

• Downloaded 755 times
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  • Site-wide: 43,075
  • In genetics: 1,865
• Year to date:
  • Site-wide: 161,100
• Since beginning of last month:
  • Site-wide: 161,837

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

• Downloaded 737 times
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  • Site-wide: 44,540
  • In genomics: 3,492
• Year to date:
  • Site-wide: 159,567
• Since beginning of last month:
  • Site-wide: 150,535

Genetic contributions to self-reported tiredness

• Downloaded 735 times
• Download rankings, all-time:
  • Site-wide: 44,761
  • In genetics: 1,925
• Year to date:
  • Site-wide: 146,639
• Since beginning of last month:
  • Site-wide: 164,969

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

• Downloaded 654 times
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  • Site-wide: 52,477
  • In genomics: 3,944
• Year to date:
  • Site-wide: 68,134
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  • Site-wide: 86,867

Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK Biobank

• Downloaded 603 times
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  • Site-wide: 58,487
  • In genetics: 2,466
• Year to date:
  • Site-wide: 154,977
• Since beginning of last month:
  • Site-wide: 144,675

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 529 times
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  • Site-wide: 68,644
  • In genetics: 2,917
• Year to date:
  • Site-wide: 143,981
• Since beginning of last month:
  • Site-wide: 95,592

Polygenic predictors of age-related decline in cognitive ability

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  • Site-wide: 70,550
  • In genomics: 4,847
• Year to date:
  • Site-wide: 158,406
• Since beginning of last month:
  • Site-wide: 150,250

Genetic contributions to trail making test performance in UK Biobank

• Downloaded 511 times
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  • Site-wide: 71,481
  • In genetics: 3,033
• Year to date:
  • Site-wide: 146,821
• Since beginning of last month:
  • Site-wide: 160,913

The influence of X chromosome variants on trait neuroticism.

• Downloaded 405 times
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  • Site-wide: 91,472
  • In genetics: 3,801
• Year to date:
  • Site-wide: 159,862
• Since beginning of last month:
  • Site-wide: 162,188

Transcriptome-wide and Stratified Genomic Structural Equation Modeling Identify Neurobiological Pathways Underlying General and Specific Cognitive Functions

• Downloaded 390 times
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  • Site-wide: 94,799
  • In genetic and genomic medicine: 498
• Year to date:
  • Site-wide: 23,651
• Since beginning of last month:
  • Site-wide: 29,058

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

• Downloaded 378 times
• Download rankings, all-time:
  • Site-wide: 97,512
  • In genetics: 4,034
• Year to date:
  • Site-wide: 159,987
• Since beginning of last month:
  • Site-wide: 148,297

Genetic contributions to health literacy

• Downloaded 377 times
• Download rankings, all-time:
  • Site-wide: 97,604
  • In epidemiology: 4,174
• Year to date:
  • Site-wide: 154,826
• Since beginning of last month:
  • Site-wide: 146,697