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Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 63,093 bioRxiv papers from 279,869 authors.

Author: Oliver Stegle

  • ORCiD: http://orcid.org/0000-0002-8818-7193
  • Most recently observed institution: DKFZ: Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ)

Rankings

  • All-time downloads: 102,205 (rank: 63 out of 279,869)
  • Categories:
    • bioinformatics: 21,562 (rank: 74 out of 24,475)
    • cancer biology: 1,815 (rank: 1,083 out of 17,326)
    • cell biology: 12,585 (rank: 42 (tie) out of 18,574)
    • developmental biology: 5,819 (rank: 25 out of 10,372)
    • genetics: 10,697 (rank: 819 out of 27,860)
    • genomics: 46,060 (rank: 111 out of 32,047)
    • neuroscience: 183 (rank: 36,508 (tie) out of 46,307)
    • systems biology: 3,484 (rank: 341 out of 8,491)

Downloads per author, site-wide

Preprints

The Human Cell Atlas

cell biology more details view paper
  • Downloaded 11,717 times
  • Download rankings, all-time:
    • Site-wide: 79 out of 63,093
    • In cell biology: 3 out of 3,016
  • Year to date:
    • Site-wide: 4,631 out of 63,093
  • Since beginning of last month:
    • Site-wide: 4,352 out of 63,093

Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

genomics more details view paper
  • Downloaded 7,526 times
  • Download rankings, all-time:
    • Site-wide: 184 out of 63,093
    • In genomics: 53 out of 4,333
  • Year to date:
    • Site-wide: 32 out of 63,093
  • Since beginning of last month:
    • Site-wide: 72 out of 63,093

Accurate prediction of single-cell DNA methylation states using deep learning

bioinformatics more details view paper
  • Downloaded 5,855 times
  • Download rankings, all-time:
    • Site-wide: 310 out of 63,093
    • In bioinformatics: 58 out of 6,276
  • Year to date:
    • Site-wide: 10,061 out of 63,093
  • Since beginning of last month:
    • Site-wide: 11,871 out of 63,093

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 5,734 times
  • Download rankings, all-time:
    • Site-wide: 318 out of 63,093
    • In genomics: 85 out of 4,333
  • Year to date:
    • Site-wide: 130 out of 63,093
  • Since beginning of last month:
    • Site-wide: 193 out of 63,093

LIMIX: genetic analysis of multiple traits

genetics more details view paper
  • Downloaded 5,700 times
  • Download rankings, all-time:
    • Site-wide: 323 out of 63,093
    • In genetics: 40 out of 3,582
  • Year to date:
    • Site-wide: 11,242 out of 63,093
  • Since beginning of last month:
    • Site-wide: 17,092 out of 63,093

Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification

developmental biology more details view paper
  • Downloaded 4,700 times
  • Download rankings, all-time:
    • Site-wide: 455 out of 63,093
    • In developmental biology: 5 out of 1,878
  • Year to date:
    • Site-wide: 80 out of 63,093
  • Since beginning of last month:
    • Site-wide: 394 out of 63,093

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells

genomics more details view paper
  • Downloaded 4,509 times
  • Download rankings, all-time:
    • Site-wide: 493 out of 63,093
    • In genomics: 129 out of 4,333
  • Year to date:
    • Site-wide: 6,673 out of 63,093
  • Since beginning of last month:
    • Site-wide: 9,522 out of 63,093

Multi-Omics factor analysis - a framework for unsupervised integration of multi-omic data sets

bioinformatics more details view paper
  • Downloaded 4,494 times
  • Download rankings, all-time:
    • Site-wide: 497 out of 63,093
    • In bioinformatics: 102 out of 6,276
  • Year to date:
    • Site-wide: 3,109 out of 63,093
  • Since beginning of last month:
    • Site-wide: 11,574 out of 63,093

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

genomics more details view paper
  • Downloaded 4,207 times
  • Download rankings, all-time:
    • Site-wide: 573 out of 63,093
    • In genomics: 152 out of 4,333
  • Year to date:
    • Site-wide: 1,155 out of 63,093
  • Since beginning of last month:
    • Site-wide: 1,810 out of 63,093

Cardelino: Integrating whole exomes and single-cell transcriptomes to reveal phenotypic impact of somatic variants

genomics more details view paper
  • Downloaded 3,833 times
  • Download rankings, all-time:
    • Site-wide: 685 out of 63,093
    • In genomics: 181 out of 4,333
  • Year to date:
    • Site-wide: 207 out of 63,093
  • Since beginning of last month:
    • Site-wide: 50 out of 63,093

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types

genomics more details view paper
  • Downloaded 3,470 times
  • Download rankings, all-time:
    • Site-wide: 831 out of 63,093
    • In genomics: 214 out of 4,333
  • Year to date:
    • Site-wide: 2,077 out of 63,093
  • Since beginning of last month:
    • Site-wide: 2,463 out of 63,093

Modelling cell-cell interactions from spatial molecular data with spatial variance component analysis

bioinformatics more details view paper
  • Downloaded 3,035 times
  • Download rankings, all-time:
    • Site-wide: 1,058 out of 63,093
    • In bioinformatics: 216 out of 6,276
  • Year to date:
    • Site-wide: 1,388 out of 63,093
  • Since beginning of last month:
    • Site-wide: 2,578 out of 63,093

Scalable latent-factor models applied to single-cell RNA-seq data separate biological drivers from confounding effects

bioinformatics more details view paper
  • Downloaded 2,770 times
  • Download rankings, all-time:
    • Site-wide: 1,264 out of 63,093
    • In bioinformatics: 258 out of 6,276
  • Year to date:
    • Site-wide: 41,307 out of 63,093
  • Since beginning of last month:
    • Site-wide: 49,916 out of 63,093

Temporal mixture modelling of single-cell RNA-seq data resolves a CD4+ T cell fate bifurcation

systems biology more details view paper
  • Downloaded 2,721 times
  • Download rankings, all-time:
    • Site-wide: 1,299 out of 63,093
    • In systems biology: 28 out of 1,791
  • Year to date:
    • Site-wide: 20,043 out of 63,093
  • Since beginning of last month:
    • Site-wide: 29,960 out of 63,093

Kipoi: accelerating the community exchange and reuse of predictive models for genomics

bioinformatics more details view paper
  • Downloaded 2,695 times
  • Download rankings, all-time:
    • Site-wide: 1,315 out of 63,093
    • In bioinformatics: 266 out of 6,276
  • Year to date:
    • Site-wide: 744 out of 63,093
  • Since beginning of last month:
    • Site-wide: 2,344 out of 63,093

SpatialDE - Identification of spatially variable genes

genomics more details view paper
  • Downloaded 2,685 times
  • Download rankings, all-time:
    • Site-wide: 1,325 out of 63,093
    • In genomics: 305 out of 4,333
  • Year to date:
    • Site-wide: 11,271 out of 63,093
  • Since beginning of last month:
    • Site-wide: 16,181 out of 63,093

Common genetic variation drives molecular heterogeneity in human iPSCs

genomics more details view paper
  • Downloaded 2,572 times
  • Download rankings, all-time:
    • Site-wide: 1,419 out of 63,093
    • In genomics: 325 out of 4,333
  • Year to date:
    • Site-wide: 34,407 out of 63,093
  • Since beginning of last month:
    • Site-wide: 40,735 out of 63,093

A linear mixed model approach to study multivariate gene-environment interactions

genetics more details view paper
  • Downloaded 2,062 times
  • Download rankings, all-time:
    • Site-wide: 2,116 out of 63,093
    • In genetics: 205 out of 3,582
  • Year to date:
    • Site-wide: 4,597 out of 63,093
  • Since beginning of last month:
    • Site-wide: 5,865 out of 63,093

A Pan-Cancer Transcriptome Analysis Reveals Pervasive Regulation through Tumor-Associated Alternative Promoters

genomics more details view paper
  • Downloaded 1,951 times
  • Download rankings, all-time:
    • Site-wide: 2,348 out of 63,093
    • In genomics: 493 out of 4,333
  • Year to date:
    • Site-wide: 2,803 out of 63,093
  • Since beginning of last month:
    • Site-wide: 737 out of 63,093

Single-cell RNA-seq of differentiating iPS cells reveals dynamic genetic effects on gene expression

genomics more details view paper
  • Downloaded 1,764 times
  • Download rankings, all-time:
    • Site-wide: 2,777 out of 63,093
    • In genomics: 563 out of 4,333
  • Year to date:
    • Site-wide: 511 out of 63,093
  • Since beginning of last month:
    • Site-wide: 551 out of 63,093

Assessing the Gene Regulatory Landscape in 1,188 Human Tumors

cancer biology more details view paper
  • Downloaded 1,227 times
  • Download rankings, all-time:
    • Site-wide: 5,070 out of 63,093
    • In cancer biology: 133 out of 2,078
  • Year to date:
    • Site-wide: 17,894 out of 63,093
  • Since beginning of last month:
    • Site-wide: 17,145 out of 63,093

Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

bioinformatics more details view paper
  • Downloaded 1,143 times
  • Download rankings, all-time:
    • Site-wide: 5,716 out of 63,093
    • In bioinformatics: 1,095 out of 6,276
  • Year to date:
    • Site-wide: 10,587 out of 63,093
  • Since beginning of last month:
    • Site-wide: 15,433 out of 63,093

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

developmental biology more details view paper
  • Downloaded 1,119 times
  • Download rankings, all-time:
    • Site-wide: 5,924 out of 63,093
    • In developmental biology: 116 out of 1,878
  • Year to date:
    • Site-wide: 1,231 out of 63,093
  • Since beginning of last month:
    • Site-wide: 334 out of 63,093

Screening for genes that accelerate the epigenetic ageing clock in humans reveals a role for the H3K36 methyltransferase NSD1

genomics more details view paper
  • Downloaded 1,069 times
  • Download rankings, all-time:
    • Site-wide: 6,398 out of 63,093
    • In genomics: 1,055 out of 4,333
  • Year to date:
    • Site-wide: 1,335 out of 63,093
  • Since beginning of last month:
    • Site-wide: 4,957 out of 63,093

Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference

bioinformatics more details view paper
  • Downloaded 1,027 times
  • Download rankings, all-time:
    • Site-wide: 6,819 out of 63,093
    • In bioinformatics: 1,241 out of 6,276
  • Year to date:
    • Site-wide: 1,423 out of 63,093
  • Since beginning of last month:
    • Site-wide: 1,470 out of 63,093

LiMMBo: a simple, scalable approach for linear mixed models in high-dimensional genetic association studies

genomics more details view paper
  • Downloaded 1,001 times
  • Download rankings, all-time:
    • Site-wide: 7,088 out of 63,093
    • In genomics: 1,139 out of 4,333
  • Year to date:
    • Site-wide: 19,164 out of 63,093
  • Since beginning of last month:
    • Site-wide: 19,697 out of 63,093

Population-scale proteome variation in human induced pluripotent stem cells

genomics more details view paper
  • Downloaded 956 times
  • Download rankings, all-time:
    • Site-wide: 7,627 out of 63,093
    • In genomics: 1,208 out of 4,333
  • Year to date:
    • Site-wide: 7,705 out of 63,093
  • Since beginning of last month:
    • Site-wide: 11,368 out of 63,093

Genome-scale oscillations in DNA methylation during exit from pluripotency

genomics more details view paper
  • Downloaded 934 times
  • Download rankings, all-time:
    • Site-wide: 7,920 out of 63,093
    • In genomics: 1,242 out of 4,333
  • Year to date:
    • Site-wide: 27,632 out of 63,093
  • Since beginning of last month:
    • Site-wide: 24,753 out of 63,093

Genome-wide Analysis of Differential Transcriptional and Epigenetic Variability Across Human Immune Cell Types

genomics more details view paper
  • Downloaded 923 times
  • Download rankings, all-time:
    • Site-wide: 8,093 out of 63,093
    • In genomics: 1,259 out of 4,333
  • Year to date:
    • Site-wide: 44,700 out of 63,093
  • Since beginning of last month:
    • Site-wide: 40,057 out of 63,093

Joint genetic analysis using variant sets reveals polygenic gene-context interactions

genetics more details view paper
  • Downloaded 880 times
  • Download rankings, all-time:
    • Site-wide: 8,739 out of 63,093
    • In genetics: 655 out of 3,582
  • Year to date:
    • Site-wide: 56,666 out of 63,093
  • Since beginning of last month:
    • Site-wide: 61,032 out of 63,093

Comparative architectures of direct and social genetic effects from the genome-wide association study of 170 phenotypes in laboratory mice

genetics more details view paper
  • Downloaded 875 times
  • Download rankings, all-time:
    • Site-wide: 8,794 out of 63,093
    • In genetics: 662 out of 3,582
  • Year to date:
    • Site-wide: 5,657 out of 63,093
  • Since beginning of last month:
    • Site-wide: 19,839 out of 63,093

Identifying extrinsic versus intrinsic drivers of variation in cell behaviour in human iPS cell lines from healthy donors

cell biology more details view paper
  • Downloaded 868 times
  • Download rankings, all-time:
    • Site-wide: 8,907 out of 63,093
    • In cell biology: 306 out of 3,016
  • Year to date:
    • Site-wide: 18,087 out of 63,093
  • Since beginning of last month:
    • Site-wide: 31,686 out of 63,093

Genomic determinants of protein abundance variation in colorectal cancer cells

systems biology more details view paper
  • Downloaded 763 times
  • Download rankings, all-time:
    • Site-wide: 10,809 out of 63,093
    • In systems biology: 307 out of 1,791
  • Year to date:
    • Site-wide: 42,584 out of 63,093
  • Since beginning of last month:
    • Site-wide: 45,647 out of 63,093

Genomic Rearrangements Considered as Quantitative Traits

genetics more details view paper
  • Downloaded 705 times
  • Download rankings, all-time:
    • Site-wide: 12,106 out of 63,093
    • In genetics: 855 out of 3,582
  • Year to date:
    • Site-wide: 50,436 out of 63,093
  • Since beginning of last month:
    • Site-wide: 48,573 out of 63,093

Tandem duplications lead to loss of fitness effects in CRISPR-Cas9 data

genomics more details view paper
  • Downloaded 652 times
  • Download rankings, all-time:
    • Site-wide: 13,519 out of 63,093
    • In genomics: 1,810 out of 4,333
  • Year to date:
    • Site-wide: 28,861 out of 63,093
  • Since beginning of last month:
    • Site-wide: 40,669 out of 63,093

Integrative Genome-wide Analysis of the Determinants of RNA Splicing in Kidney Renal Clear Cell Carcinoma

cancer biology more details view paper
  • Downloaded 588 times
  • Download rankings, all-time:
    • Site-wide: 15,613 out of 63,093
    • In cancer biology: 464 out of 2,078
  • Year to date:
    • Site-wide: 56,758 out of 63,093
  • Since beginning of last month:
    • Site-wide: 51,893 out of 63,093

Robustness and applicability of functional genomics tools on scRNA-seq data

bioinformatics more details view paper
  • Downloaded 543 times
  • Download rankings, all-time:
    • Site-wide: 17,356 out of 63,093
    • In bioinformatics: 2,632 out of 6,276
  • Year to date:
    • Site-wide: 4,312 out of 63,093
  • Since beginning of last month:
    • Site-wide: 181 out of 63,093

Multi-Tissue DNA Methylation Age Predictor In Mouse

genomics more details view paper
  • Downloaded 513 times
  • Download rankings, all-time:
    • Site-wide: 18,651 out of 63,093
    • In genomics: 2,216 out of 4,333
  • Year to date:
    • Site-wide: 52,612 out of 63,093
  • Since beginning of last month:
    • Site-wide: 43,660 out of 63,093

Interactions between genetic variation and cellular environment in skeletal muscle gene expression

genetics more details view paper
  • Downloaded 475 times
  • Download rankings, all-time:
    • Site-wide: 20,516 out of 63,093
    • In genetics: 1,382 out of 3,582
  • Year to date:
    • Site-wide: 58,104 out of 63,093
  • Since beginning of last month:
    • Site-wide: 60,976 out of 63,093

Systematic assessment of regulatory effects of human disease variants in pluripotent cells

genomics more details view paper
  • Downloaded 469 times
  • Download rankings, all-time:
    • Site-wide: 20,818 out of 63,093
    • In genomics: 2,370 out of 4,333
  • Year to date:
    • Site-wide: 5,535 out of 63,093
  • Since beginning of last month:
    • Site-wide: 240 out of 63,093

Discovery and Quality Analysis of a Comprehensive Set of Structural Variants and Short Tandem Repeats

genomics more details view paper
  • Downloaded 369 times
  • Download rankings, all-time:
    • Site-wide: 27,159 out of 63,093
    • In genomics: 2,789 out of 4,333
  • Year to date:
    • Site-wide: 8,222 out of 63,093
  • Since beginning of last month:
    • Site-wide: 8,659 out of 63,093

Multi-omics characterization of interaction-mediated control of human protein abundance levels

genomics more details view paper
  • Downloaded 368 times
  • Download rankings, all-time:
    • Site-wide: 27,217 out of 63,093
    • In genomics: 2,797 out of 4,333
  • Year to date:
    • Site-wide: 19,462 out of 63,093
  • Since beginning of last month:
    • Site-wide: 30,783 out of 63,093

Genomic properties of structural variants and short tandem repeats that impact gene expression and complex traits in humans

genomics more details view paper
  • Downloaded 353 times
  • Download rankings, all-time:
    • Site-wide: 28,331 out of 63,093
    • In genomics: 2,870 out of 4,333
  • Year to date:
    • Site-wide: 8,860 out of 63,093
  • Since beginning of last month:
    • Site-wide: 10,225 out of 63,093

In-depth genetic analysis of 6p21.3 reveals insights into associations between HLA types and complex traits and disease

genomics more details view paper
  • Downloaded 202 times
  • Download rankings, all-time:
    • Site-wide: 43,927 out of 63,093
    • In genomics: 3,654 out of 4,333
  • Year to date:
    • Site-wide: 20,027 out of 63,093
  • Since beginning of last month:
    • Site-wide: 23,420 out of 63,093

Using the past to estimate sensory uncertainty

neuroscience more details view paper
  • Downloaded 183 times
  • Download rankings, all-time:
    • Site-wide: 46,420 out of 63,093
    • In neuroscience: 8,186 out of 11,288
  • Year to date:
    • Site-wide: 22,469 out of 63,093
  • Since beginning of last month:
    • Site-wide: 31,712 out of 63,093

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