Author: Dorret Boomsma

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Preprints

Meta-Analysis of Genome-Wide Association Studies of Hoarding Symptoms in 27 537 Individuals

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

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The genetic architecture of the human cerebral cortex

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A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries

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A reference panel of 64,976 haplotypes for genotype imputation

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Greater male than female variability in regional brain structure across the lifespan

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Investigating the Genetic Architecture of Non-Cognitive Skills Using GWAS-by-Subtraction

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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Within-sibship GWAS improve estimates of direct genetic effects

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Integrative approaches for large-scale transcriptome-wide association studies

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Genome-wide association study identifies 48 common genetic variants associated with handedness

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Large-scale association analyses identify host factors influencing human gut microbiome composition

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

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Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

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Genetic insights into the biological mechanisms governing human ovarian ageing

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Life-span development of functional brain networks as assessed with minimum spanning tree analysis of resting state EEG.

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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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Parental influences on offspring education: indirect genetic effects of non-cognitive skills

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

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Stratified Linkage Disequilibrium Score Regression reveals enrichment of eQTL effects on complex traits is not tissue specific

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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Genetic Association Study of Childhood Aggression across raters, instruments and age

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Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

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Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

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Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

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  • Site-wide: 30,002
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Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

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Planar cell polarity pathway and development of the human visual cortex

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Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

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Genome-wide association study of plasma triglycerides, phospholipids and relation to cardio-metabolic risk factors

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Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

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Predicting biological age based on the BBMRI-NL 1H-NMR metabolomics repository

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Genome-wide association analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people

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Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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Incorporating polygenic scores in the twin model to estimate genotype-environment covariance: exploration of statistical power

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The genomic architecture of blood metabolites based on a decade of genome-wide analyses

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Genome-wide identification of directed gene networks using large-scale population genomics data

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Extending Causality Tests With Genetic Instruments: An Integration Of Mendelian Randomization And The Classical Twin Design

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Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

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Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity

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Genetic overlap between schizophrenia and developmental psychopathology: a longitudinal approach applied to common childhood disorders between age 7 and 15 years

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Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

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Genetic risk for major depressive disorder and loneliness in gender-specific associations with coronary artery disease

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Multivariate GWAS elucidates the genetic architecture of alcohol consumption and misuse, corrects biases, and reveals novel associations with disease

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Intergenerational transmission of education and ADHD: Effects of parental genotypes

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A genome-wide association study of total child psychiatric problems scores

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Genetic variation in the Major Histocompatibility Complex and association with depression

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EEG-based age-prediction models as stable and heritable indicators of brain maturational level in children and adolescents

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Genetics of fasting indices of glucose homeostasis using GWIS unravels tight relationships with inflammatory markers

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Novel polygenic risk score links depression-related cortical transcriptomic changes to brain morphology and symptom severity

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Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

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Contribution of genetic and environmental factors to the onset of preclinical Alzheimer's disease - a monozygotic twin study

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Integrative multi-omics analysis of childhood aggressive behavior

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Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

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Genetic meta-analysis of obsessive-compulsive disorder and self-report compulsive symptoms.

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Correction for both common and rare cell types in blood is important to identify genes that correlate with age

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Ketone body 3-hydroxybutyrate: a biomarker of aggression?

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Genome-wide association study of liking of physical activity in the UK Biobank

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Investigating the relationships between unfavorable sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

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Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study

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Genome-wide Association Study identifies two novel loci for Gilles de la Tourette Syndrome

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Multilevel Twin Models: Geographical Region as a Third Level Variable

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The power to detect cultural transmission in the Nuclear Twin Family design with and without polygenic risk scores and in the Transmitted-Non-transmitted (alleles) design

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Safe linkage of cohort and population-based register data in a genome-wide association study on health care expenditure

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Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

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On the Etiology of Aesthetic Chills: a Behavioral Genetic Study

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Heritability of Urinary Amines, Organic Acids, and Steroid Hormones in Children

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