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Author: Samuli Ripatti

  • ORCiD: http://orcid.org/0000-0002-0504-1202
  • Most recently observed institution: Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland; The Broad Institute of MIT and Harvard, Cambridge, MA, USA

Rankings

  • All-time downloads: 76,794 (rank: 2,125 )
  • Categories:
    • bioinformatics: 2,220 (rank: 7,314 (tie) )
    • cardiovascular medicine: 541 (rank: 1,070 (tie) )
    • cell biology: 168 (rank: 39,068 (tie) )
    • epidemiology: 319 (rank: 23,333 (tie) )
    • genetic and genomic medicine: 2,805 (rank: 1,140 )
    • genetics: 41,528 (rank: 113 )
    • genomics: 25,315 (rank: 476 )
    • infectious diseases: 1,130 (rank: 24,650 (tie) )
    • oncology: 916 (rank: 755 (tie) )
    • sports medicine: 322 (rank: 440 (tie) )
    • systems biology: 1,530 (rank: 2,950 )

Downloads per author, site-wide

Preprints

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 11,087 times
  • Download rankings, all-time:
    • Site-wide: 853
    • In genomics: 61
  • Year to date:
    • Site-wide: 1,347
  • Since beginning of last month:
    • Site-wide: 17,127

Genetics of 38 blood and urine biomarkers in the UK Biobank

genetics more details view paper
  • Downloaded 7,537 times
  • Download rankings, all-time:
    • Site-wide: 1,392
    • In genetics: 38
  • Year to date:
    • Site-wide: 2,435
  • Since beginning of last month:
    • Site-wide: 2,548

A reference panel of 64,976 haplotypes for genotype imputation

genetics more details view paper
  • Downloaded 4,602 times
  • Download rankings, all-time:
    • Site-wide: 2,698
    • In genetics: 90
  • Year to date:
    • Site-wide: 123,215
  • Since beginning of last month:
    • Site-wide: 105,688

Phenome-wide association studies (PheWAS) across large "real-world data" population cohorts support drug target validation

genetics more details view paper
  • Downloaded 3,612 times
  • Download rankings, all-time:
    • Site-wide: 3,801
    • In genetics: 132
  • Year to date:
    • Site-wide: 41,071
  • Since beginning of last month:
    • Site-wide: 14,286

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,216 times
  • Download rankings, all-time:
    • Site-wide: 4,477
    • In genetics: 171
  • Year to date:
    • Site-wide: 37,030
  • Since beginning of last month:
    • Site-wide: 103,740

Polygenic and clinical risk scores and their impact on age at onset of cardiometabolic diseases and common cancers

genomics more details view paper
  • Downloaded 2,917 times
  • Download rankings, all-time:
    • Site-wide: 5,119
    • In genomics: 517
  • Year to date:
    • Site-wide: 24,921
  • Since beginning of last month:
    • Site-wide: 13,467

Genome-wide association study identifies 48 common genetic variants associated with handedness

genetics more details view paper
  • Downloaded 2,711 times
  • Download rankings, all-time:
    • Site-wide: 5,663
    • In genetics: 238
  • Year to date:
    • Site-wide: 23,648
  • Since beginning of last month:
    • Site-wide: 10,533

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

genetics more details view paper
  • Downloaded 2,582 times
  • Download rankings, all-time:
    • Site-wide: 6,103
    • In genetics: 256
  • Year to date:
    • Site-wide: 25,541
  • Since beginning of last month:
    • Site-wide: None

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

genomics more details view paper
  • Downloaded 2,108 times
  • Download rankings, all-time:
    • Site-wide: 8,245
    • In genomics: 852
  • Year to date:
    • Site-wide: 144,327
  • Since beginning of last month:
    • Site-wide: None

Cell specific eQTL analysis without sorting cells

genetics more details view paper
  • Downloaded 2,015 times
  • Download rankings, all-time:
    • Site-wide: 8,806
    • In genetics: 378
  • Year to date:
    • Site-wide: 140,810
  • Since beginning of last month:
    • Site-wide: None

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

genetics more details view paper
  • Downloaded 1,935 times
  • Download rankings, all-time:
    • Site-wide: 9,336
    • In genetics: 396
  • Year to date:
    • Site-wide: 76,705
  • Since beginning of last month:
    • Site-wide: 22,997

Refining fine-mapping: effect sizes and regional heritability

genetics more details view paper
  • Downloaded 1,620 times
  • Download rankings, all-time:
    • Site-wide: 12,148
    • In genetics: 553
  • Year to date:
    • Site-wide: 25,755
  • Since beginning of last month:
    • Site-wide: 7,991

metaCCA: Summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

bioinformatics more details view paper
  • Downloaded 1,611 times
  • Download rankings, all-time:
    • Site-wide: 12,241
    • In bioinformatics: 1,409
  • Year to date:
    • Site-wide: 115,701
  • Since beginning of last month:
    • Site-wide: None

Exome sequencing identifies high-impact trait-associated alleles enriched in Finns

genomics more details view paper
  • Downloaded 1,475 times
  • Download rankings, all-time:
    • Site-wide: 13,905
    • In genomics: 1,418
  • Year to date:
    • Site-wide: 82,846
  • Since beginning of last month:
    • Site-wide: 62,689

FINEMAP: Efficient variable selection using summary data from genome-wide association studies

genetics more details view paper
  • Downloaded 1,271 times
  • Download rankings, all-time:
    • Site-wide: 17,457
    • In genetics: 812
  • Year to date:
    • Site-wide: 138,746
  • Since beginning of last month:
    • Site-wide: None

Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

genomics more details view paper
  • Downloaded 1,238 times
  • Download rankings, all-time:
    • Site-wide: 18,167
    • In genomics: 1,759
  • Year to date:
    • Site-wide: 73,850
  • Since beginning of last month:
    • Site-wide: 13,586

Genetics of human plasma lipidome: Understanding lipid metabolism and its link to diseases beyond traditional lipids

genetics more details view paper
  • Downloaded 1,206 times
  • Download rankings, all-time:
    • Site-wide: 18,871
    • In genetics: 865
  • Year to date:
    • Site-wide: 85,404
  • Since beginning of last month:
    • Site-wide: 62,827

Genomic prediction of coronary heart disease

genomics more details view paper
  • Downloaded 1,181 times
  • Download rankings, all-time:
    • Site-wide: 19,467
    • In genomics: 1,886
  • Year to date:
    • Site-wide: 138,066
  • Since beginning of last month:
    • Site-wide: None

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
  • Downloaded 1,164 times
  • Download rankings, all-time:
    • Site-wide: 19,876
    • In genetics: 912
  • Year to date:
    • Site-wide: 104,635
  • Since beginning of last month:
    • Site-wide: 103,652

Haplotype sharing provides insights into fine-scale population history and disease in Finland

genetics more details view paper
  • Downloaded 1,152 times
  • Download rankings, all-time:
    • Site-wide: 20,200
    • In genetics: 931
  • Year to date:
    • Site-wide: 91,906
  • Since beginning of last month:
    • Site-wide: 105,885

Sleep apnoea is a risk factor for severe COVID-19

infectious diseases more details view paper
  • Downloaded 1,130 times
  • Download rankings, all-time:
    • Site-wide: 20,775
    • In infectious diseases: 1,971
  • Year to date:
    • Site-wide: 19,052
  • Since beginning of last month:
    • Site-wide: 53,129

Geographic variation and bias in polygenic scores of complex diseases and traits in Finland

genetics more details view paper
  • Downloaded 1,051 times
  • Download rankings, all-time:
    • Site-wide: 23,091
    • In genetics: 1,059
  • Year to date:
    • Site-wide: 134,407
  • Since beginning of last month:
    • Site-wide: 78,547

The rate of false polymorphisms introduced when imputing genotypes from global imputation panels

genetics more details view paper
  • Downloaded 988 times
  • Download rankings, all-time:
    • Site-wide: 25,277
    • In genetics: 1,153
  • Year to date:
    • Site-wide: 116,263
  • Since beginning of last month:
    • Site-wide: 105,752

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

genomics more details view paper
  • Downloaded 981 times
  • Download rankings, all-time:
    • Site-wide: 25,536
    • In genomics: 2,360
  • Year to date:
    • Site-wide: 116,029
  • Since beginning of last month:
    • Site-wide: None

Polygenic risk, susceptibility genes, and breast cancer over the life course

oncology more details view paper
  • Downloaded 916 times
  • Download rankings, all-time:
    • Site-wide: 28,188
    • In oncology: 36
  • Year to date:
    • Site-wide: 48,681
  • Since beginning of last month:
    • Site-wide: 70,176

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

genetics more details view paper
  • Downloaded 862 times
  • Download rankings, all-time:
    • Site-wide: 30,784
    • In genetics: 1,415
  • Year to date:
    • Site-wide: 105,062
  • Since beginning of last month:
    • Site-wide: None

Towards a molecular systems model of coronary artery disease

systems biology more details view paper
  • Downloaded 841 times
  • Download rankings, all-time:
    • Site-wide: 31,832
    • In systems biology: 652
  • Year to date:
    • Site-wide: 142,190
  • Since beginning of last month:
    • Site-wide: 114,311

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

genomics more details view paper
  • Downloaded 799 times
  • Download rankings, all-time:
    • Site-wide: 34,183
    • In genomics: 2,911
  • Year to date:
    • Site-wide: 115,435
  • Since beginning of last month:
    • Site-wide: 75,789

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

genetics more details view paper
  • Downloaded 796 times
  • Download rankings, all-time:
    • Site-wide: 34,338
    • In genetics: 1,574
  • Year to date:
    • Site-wide: 25,138
  • Since beginning of last month:
    • Site-wide: 22,620

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 776 times
  • Download rankings, all-time:
    • Site-wide: 35,625
    • In genomics: 2,997
  • Year to date:
    • Site-wide: 117,854
  • Since beginning of last month:
    • Site-wide: 104,863

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

genomics more details view paper
  • Downloaded 745 times
  • Download rankings, all-time:
    • Site-wide: 37,712
    • In genomics: 3,118
  • Year to date:
    • Site-wide: 150,907
  • Since beginning of last month:
    • Site-wide: None

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

genetics more details view paper
  • Downloaded 743 times
  • Download rankings, all-time:
    • Site-wide: 37,821
    • In genetics: 1,709
  • Year to date:
    • Site-wide: 31,821
  • Since beginning of last month:
    • Site-wide: 99,611

Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health

systems biology more details view paper
  • Downloaded 689 times
  • Download rankings, all-time:
    • Site-wide: 41,833
    • In systems biology: 910
  • Year to date:
    • Site-wide: 17,738
  • Since beginning of last month:
    • Site-wide: 14,113

CCR5-del32 is not deleterious in the homozygous state in humans

genetics more details view paper
  • Downloaded 682 times
  • Download rankings, all-time:
    • Site-wide: 42,426
    • In genetics: 1,906
  • Year to date:
    • Site-wide: 121,549
  • Since beginning of last month:
    • Site-wide: None

Polygenic risk score of alcohol consumption predicts alcohol-related morbidity and all-cause mortality

genomics more details view paper
  • Downloaded 666 times
  • Download rankings, all-time:
    • Site-wide: 43,770
    • In genomics: 3,494
  • Year to date:
    • Site-wide: 80,433
  • Since beginning of last month:
    • Site-wide: 41,185

Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

genomics more details view paper
  • Downloaded 652 times
  • Download rankings, all-time:
    • Site-wide: 45,033
    • In genomics: 3,581
  • Year to date:
    • Site-wide: 66,202
  • Since beginning of last month:
    • Site-wide: 41,536

MetaPhat: Detecting and decomposing multivariate associations from univariate genome-wide association statistics

bioinformatics more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 49,049
    • In bioinformatics: 5,041
  • Year to date:
    • Site-wide: 140,761
  • Since beginning of last month:
    • Site-wide: 114,380

Communicating polygenic and non-genetic risk for atherosclerotic cardiovascular disease - An observational follow-up study

genetic and genomic medicine more details view paper
  • Downloaded 605 times
  • Download rankings, all-time:
    • Site-wide: 49,533
    • In genetic and genomic medicine: 199
  • Year to date:
    • Site-wide: 29,101
  • Since beginning of last month:
    • Site-wide: 53,682

Genetic analyses on the health impacts of testosterone highlight effects on female-specific diseases and sex differences

genetic and genomic medicine more details view paper
  • Downloaded 558 times
  • Download rankings, all-time:
    • Site-wide: 54,795
    • In genetic and genomic medicine: 222
  • Year to date:
    • Site-wide: 7,843
  • Since beginning of last month:
    • Site-wide: 90,015

biMM: Efficient estimation of genetic variances and covariances for cohorts with high-dimensional phenotype measurements

genetics more details view paper
  • Downloaded 557 times
  • Download rankings, all-time:
    • Site-wide: 54,914
    • In genetics: 2,421
  • Year to date:
    • Site-wide: 140,824
  • Since beginning of last month:
    • Site-wide: 62,958

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

genetic and genomic medicine more details view paper
  • Downloaded 521 times
  • Download rankings, all-time:
    • Site-wide: 59,522
    • In genetic and genomic medicine: 247
  • Year to date:
    • Site-wide: 8,712
  • Since beginning of last month:
    • Site-wide: 66,504

Whole genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

genetics more details view paper
  • Downloaded 500 times
  • Download rankings, all-time:
    • Site-wide: 62,273
    • In genetics: 2,748
  • Year to date:
    • Site-wide: 142,556
  • Since beginning of last month:
    • Site-wide: 48,827

ANGPTL8 protein-truncating variant and the risk of coronary disease, type 2 diabetes and adverse effects

genetic and genomic medicine more details view paper
  • Downloaded 392 times
  • Download rankings, all-time:
    • Site-wide: 79,927
    • In genetic and genomic medicine: 345
  • Year to date:
    • Site-wide: 69,738
  • Since beginning of last month:
    • Site-wide: 30,773

Association of Structural Variation with Cardiometabolic Traits in Finns

genetics more details view paper
  • Downloaded 368 times
  • Download rankings, all-time:
    • Site-wide: 84,745
    • In genetics: 3,698
  • Year to date:
    • Site-wide: 29,601
  • Since beginning of last month:
    • Site-wide: 97,134

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health

genetics more details view paper
  • Downloaded 358 times
  • Download rankings, all-time:
    • Site-wide: 86,645
    • In genetics: 3,773
  • Year to date:
    • Site-wide: 52,119
  • Since beginning of last month:
    • Site-wide: 21,011

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

genomics more details view paper
  • Downloaded 350 times
  • Download rankings, all-time:
    • Site-wide: 88,350
    • In genomics: 5,620
  • Year to date:
    • Site-wide: 85,614
  • Since beginning of last month:
    • Site-wide: 45,136

High-resolution population-specific recombination rates and their effect on phasing and genotype imputation

genomics more details view paper
  • Downloaded 340 times
  • Download rankings, all-time:
    • Site-wide: 90,444
    • In genomics: 5,705
  • Year to date:
    • Site-wide: 133,232
  • Since beginning of last month:
    • Site-wide: 81,239

Polygenic score for physical activity provides odds for multiple common diseases

sports medicine more details view paper
  • Downloaded 322 times
  • Download rankings, all-time:
    • Site-wide: 94,420
    • In sports medicine: 65
  • Year to date:
    • Site-wide: 17,457
  • Since beginning of last month:
    • Site-wide: 81,447

Coronary artery disease risk and lipidomic profiles are similar in familial and population-ascertained hyperlipidemias

epidemiology more details view paper
  • Downloaded 319 times
  • Download rankings, all-time:
    • Site-wide: 95,188
    • In epidemiology: 4,017
  • Year to date:
    • Site-wide: 103,497
  • Since beginning of last month:
    • Site-wide: 23,007

Loss-of-function of MFGE8 and protection against coronary atherosclerosis

cardiovascular medicine more details view paper
  • Downloaded 272 times
  • Download rankings, all-time:
    • Site-wide: 106,276
    • In cardiovascular medicine: 227
  • Year to date:
    • Site-wide: 22,038
  • Since beginning of last month:
    • Site-wide: 11,725

Clinical conditions and their impact on utility of genetic scores for prediction of acute coronary syndrome

cardiovascular medicine more details view paper
  • Downloaded 269 times
  • Download rankings, all-time:
    • Site-wide: 106,954
    • In cardiovascular medicine: 230
  • Year to date:
    • Site-wide: 69,085
  • Since beginning of last month:
    • Site-wide: 66,844

Genetic associations and architecture of asthma-chronic obstructive pulmonary disease overlap

genetic and genomic medicine more details view paper
  • Downloaded 261 times
  • Download rankings, all-time:
    • Site-wide: 108,809
    • In genetic and genomic medicine: 539
  • Year to date:
    • Site-wide: 44,174
  • Since beginning of last month:
    • Site-wide: 38,419

Mitochondrial genome copy number in human blood-derived DNA is strongly associated with insulin levels and related metabolic traits and primarily reflects cell-type composition differences

genetic and genomic medicine more details view paper
  • Downloaded 244 times
  • Download rankings, all-time:
    • Site-wide: 112,935
    • In genetic and genomic medicine: 577
  • Year to date:
    • Site-wide: 47,537
  • Since beginning of last month:
    • Site-wide: 60,177

Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

genetic and genomic medicine more details view paper
  • Downloaded 224 times
  • Download rankings, all-time:
    • Site-wide: 118,216
    • In genetic and genomic medicine: 625
  • Year to date:
    • Site-wide: 56,369
  • Since beginning of last month:
    • Site-wide: 41,975

Multiparametric profiling of cellular lipid metabolism in hypercholesterolemia

cell biology more details view paper
  • Downloaded 168 times
  • Download rankings, all-time:
    • Site-wide: 131,710
    • In cell biology: 6,053
  • Year to date:
    • Site-wide: 40,299
  • Since beginning of last month:
    • Site-wide: None

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