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Author: Steven A Carr

Rankings

  • All-time downloads: 72,483 (rank: 3,210 )
  • Categories:
    • biochemistry: 9,672 (rank: 327 )
    • bioengineering: 17,561 (rank: 36 (tie) )
    • bioinformatics: 3,057 (rank: 6,455 )
    • cancer biology: 10,038 (rank: 289 )
    • cell biology: 5,592 (rank: 1,177 )
    • developmental biology: 508 (rank: 15,607 (tie) )
    • genetic and genomic medicine: 853 (rank: 7,670 (tie) )
    • genetics: 72 (rank: 49,876 (tie) )
    • genomics: 270 (rank: 56,590 (tie) )
    • immunology: 3,455 (rank: 4,907 (tie) )
    • microbiology: 5,097 (rank: 4,333 )
    • molecular biology: 6,407 (rank: 637 )
    • neuroscience: 5,607 (rank: 5,123 )
    • physiology: 2,403 (rank: 222 (tie) )
    • systems biology: 1,159 (rank: 5,467 (tie) )

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Preprints

ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling

immunology more details view paper

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Deep proteomics identifies shared molecular pathway alterations in synapses of schizophrenia and bipolar disorder patients and mouse model

neuroscience more details view paper

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Directed evolution of TurboID for efficient proximity labeling in living cells and organisms

bioengineering more details view paper
  • Downloaded 17,632 times
  • Download rankings, all-time:
    • Site-wide: 642
    • In bioengineering: 4
  • Year to date:
    • Site-wide: 8,100
  • Since beginning of last month:
    • Site-wide: 6,884

CRISPR/Cas9-APEX-mediated proximity labeling enables discovery of proteins associated with a predefined genomic locus in living cells

biochemistry more details view paper
  • Downloaded 6,680 times
  • Download rankings, all-time:
    • Site-wide: 2,238
    • In biochemistry: 32
  • Year to date:
    • Site-wide: 48,228
  • Since beginning of last month:
    • Site-wide: 47,932

Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

cancer biology more details view paper
  • Downloaded 5,436 times
  • Download rankings, all-time:
    • Site-wide: 2,974
    • In cancer biology: 36
  • Year to date:
    • Site-wide: 8,179
  • Since beginning of last month:
    • Site-wide: 14,480

RNA-protein interaction mapping via MS2 or Cas13-based APEX targeting

molecular biology more details view paper
  • Downloaded 4,458 times
  • Download rankings, all-time:
    • Site-wide: 3,863
    • In molecular biology: 77
  • Year to date:
    • Site-wide: 80,447
  • Since beginning of last month:
    • Site-wide: None

Split-TurboID enables contact-dependent proximity labeling in cells

cell biology more details view paper
  • Downloaded 3,607 times
  • Download rankings, all-time:
    • Site-wide: 5,250
    • In cell biology: 96
  • Year to date:
    • Site-wide: 53,815
  • Since beginning of last month:
    • Site-wide: None

SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs

immunology more details view paper
  • Downloaded 3,483 times
  • Download rankings, all-time:
    • Site-wide: 5,540
    • In immunology: 219
  • Year to date:
    • Site-wide: 28,569
  • Since beginning of last month:
    • Site-wide: 11,766

A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells

microbiology more details view paper
  • Downloaded 3,455 times
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    • Site-wide: 5,610
    • In microbiology: 368
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 32,627

Proteomics of protein trafficking by in vivo tissue-specific labeling

physiology more details view paper
  • Downloaded 2,409 times
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    • Site-wide: 9,497
    • In physiology: 14
  • Year to date:
    • Site-wide: 91,202
  • Since beginning of last month:
    • Site-wide: 108,927

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers New Wiring Regulators

neuroscience more details view paper
  • Downloaded 2,314 times
  • Download rankings, all-time:
    • Site-wide: 10,088
    • In neuroscience: 946
  • Year to date:
    • Site-wide: 185,749
  • Since beginning of last month:
    • Site-wide: None

Functional proximity mapping of RNA binding proteins uncovers a mitochondrial mRNA anchor that promotes stress recovery

molecular biology more details view paper
  • Downloaded 1,729 times
  • Download rankings, all-time:
    • Site-wide: 15,694
    • In molecular biology: 398
  • Year to date:
    • Site-wide: 130,261
  • Since beginning of last month:
    • Site-wide: 111,621

MONTE enables serial immunopeptidome, ubiquitylome, proteome, phosphoproteome, acetylome analyses of sample-limited tissues

cancer biology more details view paper
  • Downloaded 1,584 times
  • Download rankings, all-time:
    • Site-wide: 17,951
    • In cancer biology: 414
  • Year to date:
    • Site-wide: 6,783
  • Since beginning of last month:
    • Site-wide: 9,710

Specter: linear deconvolution as a new paradigm for targeted analysis of data-independent acquisition mass spectrometry proteomics

bioinformatics more details view paper
  • Downloaded 1,304 times
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    • Site-wide: 24,323
    • In bioinformatics: 2,610
  • Year to date:
    • Site-wide: 158,985
  • Since beginning of last month:
    • Site-wide: 167,373

Avant-garde: An automated data-driven DIA data curation tool.

bioinformatics more details view paper
  • Downloaded 1,185 times
  • Download rankings, all-time:
    • Site-wide: 28,269
    • In bioinformatics: 3,002
  • Year to date:
    • Site-wide: 175,968
  • Since beginning of last month:
    • Site-wide: 159,413

A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

systems biology more details view paper
  • Downloaded 1,168 times
  • Download rankings, all-time:
    • Site-wide: 28,951
    • In systems biology: 522
  • Year to date:
    • Site-wide: 159,255
  • Since beginning of last month:
    • Site-wide: 102,858

A genetic model for in vivo proximity labeling of the mammalian secretome

cell biology more details view paper
  • Downloaded 1,026 times
  • Download rankings, all-time:
    • Site-wide: 35,308
    • In cell biology: 1,456
  • Year to date:
    • Site-wide: 2,663
  • Since beginning of last month:
    • Site-wide: 11,188

Proximity-labeling reveals novel host and parasite proteins at the Toxoplasma parasitophorous vacuole membrane

microbiology more details view paper
  • Downloaded 966 times
  • Download rankings, all-time:
    • Site-wide: 38,718
    • In microbiology: 2,253
  • Year to date:
    • Site-wide: 48,810
  • Since beginning of last month:
    • Site-wide: 52,288

UbiFast, a rapid and deep-scale ubiquitylation profiling approach for biology and translational research

biochemistry more details view paper
  • Downloaded 956 times
  • Download rankings, all-time:
    • Site-wide: 39,349
    • In biochemistry: 957
  • Year to date:
    • Site-wide: 100,076
  • Since beginning of last month:
    • Site-wide: 75,219

Transcription Factor Acj6 Controls Dendrite Targeting via CombinatorialCell-Surface Codes

neuroscience more details view paper
  • Downloaded 907 times
  • Download rankings, all-time:
    • Site-wide: 42,542
    • In neuroscience: 5,617
  • Year to date:
    • Site-wide: 7,621
  • Since beginning of last month:
    • Site-wide: None

Using brain cell-type-specific protein interactomes to interpret genetic data in schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 898 times
  • Download rankings, all-time:
    • Site-wide: 43,183
    • In genetic and genomic medicine: 268
  • Year to date:
    • Site-wide: 12,892
  • Since beginning of last month:
    • Site-wide: 7,338

CBL mutations promote activation of PI3K/AKT signaling via LYN kinase

cancer biology more details view paper
  • Downloaded 861 times
  • Download rankings, all-time:
    • Site-wide: 46,052
    • In cancer biology: 1,285
  • Year to date:
    • Site-wide: 52,570
  • Since beginning of last month:
    • Site-wide: None

Mapping the unique and shared functions of oncogenic KRAS and RIT1 with proteome and transcriptome profiling

cancer biology more details view paper
  • Downloaded 732 times
  • Download rankings, all-time:
    • Site-wide: 58,414
    • In cancer biology: 1,674
  • Year to date:
    • Site-wide: 92,804
  • Since beginning of last month:
    • Site-wide: 138,374

Domain-specific quantification of prion protein in cerebrospinal fluid by targeted mass spectrometry

neuroscience more details view paper
  • Downloaded 718 times
  • Download rankings, all-time:
    • Site-wide: 60,144
    • In neuroscience: 8,220
  • Year to date:
    • Site-wide: 132,608
  • Since beginning of last month:
    • Site-wide: 160,384

A schizophrenia risk gene, NRGN, bidirectionally modulates synaptic plasticity via regulating the neuronal phosphoproteome

neuroscience more details view paper
  • Downloaded 713 times
  • Download rankings, all-time:
    • Site-wide: 60,680
    • In neuroscience: 8,260
  • Year to date:
    • Site-wide: 154,702
  • Since beginning of last month:
    • Site-wide: None

Microscaled Proteogenomic Methods for Precision Oncology

cancer biology more details view paper
  • Downloaded 692 times
  • Download rankings, all-time:
    • Site-wide: 63,351
    • In cancer biology: 1,812
  • Year to date:
    • Site-wide: 175,497
  • Since beginning of last month:
    • Site-wide: 106,688

Dual protease type XIII/pepsin digestion offers superior resolution and overlap for the analysis of histone tails by HX-MS

biochemistry more details view paper
  • Downloaded 670 times
  • Download rankings, all-time:
    • Site-wide: 66,211
    • In biochemistry: 1,741
  • Year to date:
    • Site-wide: 130,440
  • Since beginning of last month:
    • Site-wide: 106,622

Tetracyclines Modify Translation By Targeting Key Human rRNA Substructures.

cell biology more details view paper
  • Downloaded 643 times
  • Download rankings, all-time:
    • Site-wide: 70,051
    • In cell biology: 3,052
  • Year to date:
    • Site-wide: 156,987
  • Since beginning of last month:
    • Site-wide: 101,989

Brain-Specific Deletion of GIT1 Impairs Cognition and Alters Phosphorylation of Synaptic Protein Networks Implicated in Schizophrenia Susceptibility

neuroscience more details view paper
  • Downloaded 601 times
  • Download rankings, all-time:
    • Site-wide: 76,481
    • In neuroscience: 10,944
  • Year to date:
    • Site-wide: 98,021
  • Since beginning of last month:
    • Site-wide: 127,743

Novel antibodies for the simple and efficient enrichment of native O-GlcNAc modified peptides

biochemistry more details view paper
  • Downloaded 546 times
  • Download rankings, all-time:
    • Site-wide: 86,022
    • In biochemistry: 2,420
  • Year to date:
    • Site-wide: 66,481
  • Since beginning of last month:
    • Site-wide: 20,875

Glucocorticoids Induce the Expansion of an Immature Human CFU-E Population

developmental biology more details view paper
  • Downloaded 522 times
  • Download rankings, all-time:
    • Site-wide: 90,876
    • In developmental biology: 2,342
  • Year to date:
    • Site-wide: 129,587
  • Since beginning of last month:
    • Site-wide: 31,199

Automating UbiFast for High-throughput and Multiplexed Ubiquitin Enrichment

biochemistry more details view paper
  • Downloaded 516 times
  • Download rankings, all-time:
    • Site-wide: 91,993
    • In biochemistry: 2,589
  • Year to date:
    • Site-wide: 80,235
  • Since beginning of last month:
    • Site-wide: 54,316

OGT controls mammalian cell viability by regulating the proteasome/mTOR/mitochondrial axis

cell biology more details view paper
  • Downloaded 493 times
  • Download rankings, all-time:
    • Site-wide: 96,865
    • In cell biology: 5,463
  • Year to date:
    • Site-wide: 21,138
  • Since beginning of last month:
    • Site-wide: 1,669

Dual Functions of SPOP and ERG Dictate Androgen Therapy Responses in Prostate Cancer

cancer biology more details view paper
  • Downloaded 475 times
  • Download rankings, all-time:
    • Site-wide: 100,886
    • In cancer biology: 3,001
  • Year to date:
    • Site-wide: 149,414
  • Since beginning of last month:
    • Site-wide: 52,338

A conserved translation factor is required for optimal synthesis of a membrane protein family in mycobacteria

microbiology more details view paper
  • Downloaded 468 times
  • Download rankings, all-time:
    • Site-wide: 102,669
    • In microbiology: 6,523
  • Year to date:
    • Site-wide: 136,080
  • Since beginning of last month:
    • Site-wide: None

PANOPLY: A cloud-based platform for automated and reproducible proteogenomic data analysis

bioinformatics more details view paper
  • Downloaded 448 times
  • Download rankings, all-time:
    • Site-wide: 107,298
    • In bioinformatics: 9,026
  • Year to date:
    • Site-wide: 160,831
  • Since beginning of last month:
    • Site-wide: 147,424

A Bidirectional Switch in the Shank3 Phosphorylation State Biases Synapses toward Up or Down Scaling

neuroscience more details view paper
  • Downloaded 398 times
  • Download rankings, all-time:
    • Site-wide: 119,880
    • In neuroscience: 17,721
  • Year to date:
    • Site-wide: 61,105
  • Since beginning of last month:
    • Site-wide: 55,395

Highly multiplexed quantitative phosphosite assay for biology and preclinical studies

cancer biology more details view paper
  • Downloaded 394 times
  • Download rankings, all-time:
    • Site-wide: 121,006
    • In cancer biology: 3,658
  • Year to date:
    • Site-wide: 110,234
  • Since beginning of last month:
    • Site-wide: 82,879

Biomarkers to distinguish bacterial from viral pediatric clinical pneumonia in a malaria endemic setting

genomics more details view paper
  • Downloaded 270 times
  • Download rankings, all-time:
    • Site-wide: 157,136
    • In genomics: 7,896
  • Year to date:
    • Site-wide: 200,461
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    • Site-wide: None

Optimized liquid and gas phase fractionation increase HLA-peptidome coverage for primary cell and tissue samples

biochemistry more details view paper
  • Downloaded 269 times
  • Download rankings, all-time:
    • Site-wide: 157,294
    • In biochemistry: 4,784
  • Year to date:
    • Site-wide: 145,502
  • Since beginning of last month:
    • Site-wide: 122,834

Identification of a novel regulator of Clostridioides difficile cortex formation

microbiology more details view paper
  • Downloaded 248 times
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    • Site-wide: 163,232
    • In microbiology: 11,849
  • Year to date:
    • Site-wide: 123,840
  • Since beginning of last month:
    • Site-wide: None

TAILS identifies candidate substrates and biomarkers of ADAMTS7, a therapeutic protease target in coronary artery disease

molecular biology more details view paper
  • Downloaded 239 times
  • Download rankings, all-time:
    • Site-wide: 165,748
    • In molecular biology: 4,879
  • Year to date:
    • Site-wide: 62,748
  • Since beginning of last month:
    • Site-wide: 71,681

Cloud-based DIA data analysis module for signal refinement improves accuracy and throughput of large datasets.

bioinformatics more details view paper
  • Downloaded 143 times
  • Download rankings, all-time:
    • Site-wide: 187,909
    • In bioinformatics: 13,788
  • Year to date:
    • Site-wide: 137,092
  • Since beginning of last month:
    • Site-wide: 116,139

Huntingtin turnover: Modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550

biochemistry more details view paper
  • Downloaded 132 times
  • Download rankings, all-time:
    • Site-wide: 189,944
    • In biochemistry: 5,830
  • Year to date:
    • Site-wide: 59,638
  • Since beginning of last month:
    • Site-wide: 54,051

Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset

genetics more details view paper
  • Downloaded 95 times
  • Download rankings, all-time:
    • Site-wide: 195,606
    • In genetics: 6,889
  • Year to date:
    • Site-wide: 79,812
  • Since beginning of last month:
    • Site-wide: 107,436

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