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Author: Li Chen

  • ORCiD: http://orcid.org/0000-0001-8685-3466
  • Most recently observed institution: Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

Rankings

  • All-time downloads: 78,050 (rank: 1,968 )
  • Categories:
    • bioinformatics: 6,253 (rank: 1,914 (tie) )
    • biophysics: 743 (rank: 7,668 (tie) )
    • cancer biology: 1,802 (rank: 3,933 (tie) )
    • cell biology: 213 (rank: 35,492 (tie) )
    • developmental biology: 1,872 (rank: 1,877 (tie) )
    • emergency medicine: 2,624 (rank: 80 (tie) )
    • epidemiology: 12,767 (rank: 1,155 )
    • genetic and genomic medicine: 176 (rank: 10,677 (tie) )
    • genetics: 712 (rank: 21,204 (tie) )
    • genomics: 1,379 (rank: 18,031 (tie) )
    • infectious diseases: 39,847 (rank: 1,327 )
    • intensive care and critical care medicine: 2,783 (rank: 432 )
    • microbiology: 2,160 (rank: 7,203 (tie) )
    • molecular biology: 595 (rank: 11,505 (tie) )
    • neuroscience: 802 (rank: 31,724 (tie) )
    • oncology: 315 (rank: 2,798 (tie) )
    • pathology: 760 (rank: 1,836 )
    • physiology: 116 (rank: 11,386 (tie) )
    • systems biology: 1,781 (rank: 2,526 )
    • zoology: 350 (rank: 1,678 (tie) )

Downloads per author, site-wide

Preprints

ARF4-mediated Retrograde Trafficking Drives Chemoresistance in Glioblastoma

cancer biology more details view paper

No download data for this paper yet.

Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)

infectious diseases more details view paper
  • Downloaded 23,041 times
  • Download rankings, all-time:
    • Site-wide: 330
    • In infectious diseases: 124
  • Year to date:
    • Site-wide: 5,560
  • Since beginning of last month:
    • Site-wide: 9,078

The feasibility of convalescent plasma therapy in severe COVID-19 patients: a pilot study

infectious diseases more details view paper
  • Downloaded 15,825 times
  • Download rankings, all-time:
    • Site-wide: 487
    • In infectious diseases: 170
  • Year to date:
    • Site-wide: 3,676
  • Since beginning of last month:
    • Site-wide: 9,301

Diagnosis of Acute Respiratory Syndrome Coronavirus 2 Infection by Detection of Nucleocapsid Protein

epidemiology more details view paper
  • Downloaded 12,492 times
  • Download rankings, all-time:
    • Site-wide: 687
    • In epidemiology: 99
  • Year to date:
    • Site-wide: 2,310
  • Since beginning of last month:
    • Site-wide: 4,298

A Novel Triage Tool of Artificial Intelligence Assisted Diagnosis Aid System for Suspected COVID-19 pneumonia In Fever Clinics

emergency medicine more details view paper
  • Downloaded 2,624 times
  • Download rankings, all-time:
    • Site-wide: 5,729
    • In emergency medicine: 9
  • Year to date:
    • Site-wide: 7,473
  • Since beginning of last month:
    • Site-wide: 9,075

Critical Care for Patients with Severe Covid-2019 in Sichuan Province, China: Provincial Cohort Study

intensive care and critical care medicine more details view paper
  • Downloaded 1,877 times
  • Download rankings, all-time:
    • Site-wide: 9,428
    • In intensive care and critical care medicine: 42
  • Year to date:
    • Site-wide: 34,334
  • Since beginning of last month:
    • Site-wide: 30,204

A two-enzyme adaptive unit within bacterial folate metabolism

systems biology more details view paper
  • Downloaded 1,627 times
  • Download rankings, all-time:
    • Site-wide: 11,637
    • In systems biology: 208
  • Year to date:
    • Site-wide: 77,686
  • Since beginning of last month:
    • Site-wide: 117,078

GMPR: A novel normalization method for microbiome sequencing data

bioinformatics more details view paper
  • Downloaded 1,339 times
  • Download rankings, all-time:
    • Site-wide: 15,526
    • In bioinformatics: 1,822
  • Year to date:
    • Site-wide: 91,184
  • Since beginning of last month:
    • Site-wide: 75,446

Gene flow between divergent cereal- and grass-specific lineages of the rice blast fungus Magnaporthe oryzae

microbiology more details view paper
  • Downloaded 1,289 times
  • Download rankings, all-time:
    • Site-wide: 16,466
    • In microbiology: 951
  • Year to date:
    • Site-wide: 101,600
  • Since beginning of last month:
    • Site-wide: 98,057

Metabolite discovery through global annotation of untargeted metabolomics data

bioinformatics more details view paper
  • Downloaded 1,152 times
  • Download rankings, all-time:
    • Site-wide: 19,428
    • In bioinformatics: 2,262
  • Year to date:
    • Site-wide: 2,295
  • Since beginning of last month:
    • Site-wide: 4,612

Sympathetic Nerve Activity Promotes Cardiomyocyte Cell-Cycle Arrest And Binucleation

developmental biology more details view paper
  • Downloaded 1,122 times
  • Download rankings, all-time:
    • Site-wide: 20,199
    • In developmental biology: 342
  • Year to date:
    • Site-wide: 62,642
  • Since beginning of last month:
    • Site-wide: 62,195

Destin: toolkit for single-cell analysis of chromatin accessibility

bioinformatics more details view paper
  • Downloaded 1,094 times
  • Download rankings, all-time:
    • Site-wide: 20,964
    • In bioinformatics: 2,426
  • Year to date:
    • Site-wide: 133,095
  • Since beginning of last month:
    • Site-wide: 116,703

Longitudinal analysis of laboratory findings during the process of recovery for patients with COVID-19

infectious diseases more details view paper
  • Downloaded 981 times
  • Download rankings, all-time:
    • Site-wide: 24,610
    • In infectious diseases: 2,061
  • Year to date:
    • Site-wide: 50,707
  • Since beginning of last month:
    • Site-wide: 55,715

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

cancer biology more details view paper
  • Downloaded 966 times
  • Download rankings, all-time:
    • Site-wide: 25,206
    • In cancer biology: 617
  • Year to date:
    • Site-wide: 28,387
  • Since beginning of last month:
    • Site-wide: 55,693

MS-PyCloud: An open-source, cloud computing-based pipeline for LC-MS/MS data analysis

bioinformatics more details view paper
  • Downloaded 935 times
  • Download rankings, all-time:
    • Site-wide: 26,392
    • In bioinformatics: 3,010
  • Year to date:
    • Site-wide: 36,892
  • Since beginning of last month:
    • Site-wide: 61,511

Artificial Intelligence Assisted Early Warning System for Acute Kidney Injury Driven by Multi-Center ICU Database

intensive care and critical care medicine more details view paper
  • Downloaded 906 times
  • Download rankings, all-time:
    • Site-wide: 27,536
    • In intensive care and critical care medicine: 95
  • Year to date:
    • Site-wide: 21,398
  • Since beginning of last month:
    • Site-wide: 22,014

Base editing in Streptomyces with Cas9-deaminase fusions

microbiology more details view paper
  • Downloaded 871 times
  • Download rankings, all-time:
    • Site-wide: 29,148
    • In microbiology: 1,725
  • Year to date:
    • Site-wide: 51,355
  • Since beginning of last month:
    • Site-wide: 61,336

Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines

bioinformatics more details view paper
  • Downloaded 832 times
  • Download rankings, all-time:
    • Site-wide: 31,090
    • In bioinformatics: 3,468
  • Year to date:
    • Site-wide: 14,742
  • Since beginning of last month:
    • Site-wide: 17,557

Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord

neuroscience more details view paper
  • Downloaded 802 times
  • Download rankings, all-time:
    • Site-wide: 32,683
    • In neuroscience: 4,338
  • Year to date:
    • Site-wide: 15,385
  • Since beginning of last month:
    • Site-wide: 39,473

The Metabolites NADP+ and NADPH are the Targets of the Circadian Protein Nocturnin (Curled)

biophysics more details view paper
  • Downloaded 743 times
  • Download rankings, all-time:
    • Site-wide: 36,349
    • In biophysics: 1,121
  • Year to date:
    • Site-wide: 107,402
  • Since beginning of last month:
    • Site-wide: 105,297

BAMM-SC: A Bayesian mixture model for clustering droplet-based single cell transcriptomic data from population studies

bioinformatics more details view paper
  • Downloaded 668 times
  • Download rankings, all-time:
    • Site-wide: 41,959
    • In bioinformatics: 4,482
  • Year to date:
    • Site-wide: 94,410
  • Since beginning of last month:
    • Site-wide: 120,101

Correlation of ELISA based with random access serologic immunoassays for identifying adaptive immune response to SARS-CoV-2

pathology more details view paper
  • Downloaded 662 times
  • Download rankings, all-time:
    • Site-wide: 42,381
    • In pathology: 195
  • Year to date:
    • Site-wide: 32,992
  • Since beginning of last month:
    • Site-wide: 37,308

Genomic analyses reveal the origin of domestic ducks and identify different genetic underpinnings of wild ducks

genomics more details view paper
  • Downloaded 529 times
  • Download rankings, all-time:
    • Site-wide: 56,087
    • In genomics: 4,209
  • Year to date:
    • Site-wide: 55,679
  • Since beginning of last month:
    • Site-wide: 55,733

Tbx1 interacts genetically with Vegfr3 to regulate cardiac lymphangiogenesis in mice

developmental biology more details view paper
  • Downloaded 528 times
  • Download rankings, all-time:
    • Site-wide: 56,165
    • In developmental biology: 1,327
  • Year to date:
    • Site-wide: 120,443
  • Since beginning of last month:
    • Site-wide: 104,516

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

genomics more details view paper
  • Downloaded 522 times
  • Download rankings, all-time:
    • Site-wide: 56,964
    • In genomics: 4,244
  • Year to date:
    • Site-wide: 141,510
  • Since beginning of last month:
    • Site-wide: 120,751

MiR-505-3p, a New Repressor of Puberty Onset in Female Mice

genetics more details view paper
  • Downloaded 498 times
  • Download rankings, all-time:
    • Site-wide: 60,127
    • In genetics: 2,679
  • Year to date:
    • Site-wide: 118,516
  • Since beginning of last month:
    • Site-wide: 76,325

Interaction between DNA damage response, translation and apoptosome determines cancer susceptibility to TOP2 poisons

cancer biology more details view paper
  • Downloaded 447 times
  • Download rankings, all-time:
    • Site-wide: 67,566
    • In cancer biology: 1,954
  • Year to date:
    • Site-wide: 90,669
  • Since beginning of last month:
    • Site-wide: 70,051

CD8+ T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomas

cancer biology more details view paper
  • Downloaded 389 times
  • Download rankings, all-time:
    • Site-wide: 77,523
    • In cancer biology: 2,281
  • Year to date:
    • Site-wide: 127,639
  • Since beginning of last month:
    • Site-wide: 121,112

Bacterial fucosidase enables the production of Bombay red blood cells

molecular biology more details view paper
  • Downloaded 373 times
  • Download rankings, all-time:
    • Site-wide: 80,362
    • In molecular biology: 2,359
  • Year to date:
    • Site-wide: 94,273
  • Since beginning of last month:
    • Site-wide: 76,374

Venom Isosolenopsin A Delivers Rapid Knockdown of Fire Ant Competitors

zoology more details view paper
  • Downloaded 350 times
  • Download rankings, all-time:
    • Site-wide: 84,934
    • In zoology: 309
  • Year to date:
    • Site-wide: 143,013
  • Since beginning of last month:
    • Site-wide: 120,381

Transposon-mediated telomere destabilization: a driver of genome evolution in the blast fungus

genomics more details view paper
  • Downloaded 328 times
  • Download rankings, all-time:
    • Site-wide: 89,520
    • In genomics: 5,642
  • Year to date:
    • Site-wide: 119,750
  • Since beginning of last month:
    • Site-wide: 105,662

Toxicities of PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

oncology more details view paper
  • Downloaded 315 times
  • Download rankings, all-time:
    • Site-wide: 92,320
    • In oncology: 172
  • Year to date:
    • Site-wide: 40,389
  • Since beginning of last month:
    • Site-wide: 32,535

Multiplex Fragment Analysis Identifies SARS-CoV-2 Variants

epidemiology more details view paper
  • Downloaded 275 times
  • Download rankings, all-time:
    • Site-wide: 101,383
    • In epidemiology: 4,243
  • Year to date:
    • Site-wide: 18,135
  • Since beginning of last month:
    • Site-wide: 23,274

WEVar: a novel statistical learning framework for predicting noncoding regulatory variants

bioinformatics more details view paper
  • Downloaded 233 times
  • Download rankings, all-time:
    • Site-wide: 111,483
    • In bioinformatics: 9,320
  • Year to date:
    • Site-wide: 57,909
  • Since beginning of last month:
    • Site-wide: 93,052

Exploring differentially expressed key genes related to development of follicle by RNA-seq in Peking ducks (Anas Platyrhynchos)

developmental biology more details view paper
  • Downloaded 222 times
  • Download rankings, all-time:
    • Site-wide: 114,290
    • In developmental biology: 3,082
  • Year to date:
    • Site-wide: 142,825
  • Since beginning of last month:
    • Site-wide: 131,108

FER-mediated tyrosine phosphorylation and PIK3R2/p85β recruitment on IRS4 promotes the PI3K-AKT signaling pathway and tumorigenesis in ovarian cancer

molecular biology more details view paper
  • Downloaded 222 times
  • Download rankings, all-time:
    • Site-wide: 114,246
    • In molecular biology: 3,390
  • Year to date:
    • Site-wide: 54,295
  • Since beginning of last month:
    • Site-wide: 51,123

A missense mutation of Ip3r1 in Dp2 mice leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles

genetics more details view paper
  • Downloaded 214 times
  • Download rankings, all-time:
    • Site-wide: 116,204
    • In genetics: 4,909
  • Year to date:
    • Site-wide: 120,562
  • Since beginning of last month:
    • Site-wide: 120,942

Crif1 Promotes Osteoporosis in Mice after Radiation

cell biology more details view paper
  • Downloaded 213 times
  • Download rankings, all-time:
    • Site-wide: 116,543
    • In cell biology: 5,393
  • Year to date:
    • Site-wide: 124,977
  • Since beginning of last month:
    • Site-wide: 103,135

A Short Plus Long-Amplicon Based Sequencing Approach Improves Genomic Coverage and Variant Detection In the SARS-CoV-2 Genome

genetic and genomic medicine more details view paper
  • Downloaded 176 times
  • Download rankings, all-time:
    • Site-wide: 125,336
    • In genetic and genomic medicine: 665
  • Year to date:
    • Site-wide: 31,985
  • Since beginning of last month:
    • Site-wide: 4,373

Developmental and Intergenerational Landscape of Human Circulatory Lipidome and its Association with Obesity Risk

systems biology more details view paper
  • Downloaded 154 times
  • Download rankings, all-time:
    • Site-wide: 130,328
    • In systems biology: 2,819
  • Year to date:
    • Site-wide: 37,133
  • Since beginning of last month:
    • Site-wide: 36,756

Berberine alleviates adiposity and cardiac dysfunction in offspring exposed to gestational diabetes mellitus

physiology more details view paper
  • Downloaded 116 times
  • Download rankings, all-time:
    • Site-wide: 138,533
    • In physiology: 1,643
  • Year to date:
    • Site-wide: 91,710
  • Since beginning of last month:
    • Site-wide: 46,730

Increased ketohexokinase-A governs fructose-induced podocyte hypertrophy by IL-6/STAT3 signaling activation

pathology more details view paper
  • Downloaded 98 times
  • Download rankings, all-time:
    • Site-wide: 141,785
    • In pathology: 860
  • Year to date:
    • Site-wide: 69,222
  • Since beginning of last month:
    • Site-wide: 119,852

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