Author: Li Chen
- ORCiD: http://orcid.org/0000-0001-9372-5606
- Most recently observed institution: MinSheng Ear-Nose-Throat Hospital, Chengdu, Sichuan, China
Rankings
- All-time downloads: 95,637 (rank: 2,378 )
- Categories:
- biochemistry: 619 (rank: 17,128 (tie) )
- bioinformatics: 10,012 (rank: 1,367 )
- biophysics: 843 (rank: 11,688 (tie) )
- cancer biology: 3,270 (rank: 2,946 )
- cell biology: 697 (rank: 25,410 (tie) )
- developmental biology: 2,267 (rank: 2,541 )
- emergency medicine: 3,204 (rank: 73 (tie) )
- epidemiology: 15,354 (rank: 1,471 )
- genetic and genomic medicine: 598 (rank: 11,621 (tie) )
- genetics: 897 (rank: 23,389 (tie) )
- genomics: 1,765 (rank: 18,902 (tie) )
- health informatics: 269 (rank: 5,122 (tie) )
- immunology: 117 (rank: 54,384 (tie) )
- infectious diseases: 41,882 (rank: 1,850 )
- intensive care and critical care medicine: 3,483 (rank: 485 )
- microbiology: 2,783 (rank: 8,525 (tie) )
- molecular biology: 921 (rank: 11,986 (tie) )
- nephrology: 243 (rank: 1,514 (tie) )
- neuroscience: 962 (rank: 42,339 (tie) )
- obstetrics and gynecology: 272 (rank: 1,983 (tie) )
- oncology: 515 (rank: 4,051 (tie) )
- pathology: 1,044 (rank: 2,031 (tie) )
- physiology: 253 (rank: 13,806 (tie) )
- systems biology: 2,190 (rank: 2,886 )
- zoology: 429 (rank: 2,303 (tie) )
Downloads per author, site-wide
Preprints
Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)
infectious diseases more details view paper- Downloaded 23,844 times
- Download rankings, all-time:
- Site-wide: 473
- In infectious diseases: 182
- Year to date:
- Site-wide: 11,532
- Since beginning of last month:
- Site-wide: 14,941
The feasibility of convalescent plasma therapy in severe COVID-19 patients: a pilot study
infectious diseases more details view paper- Downloaded 16,977 times
- Download rankings, all-time:
- Site-wide: 694
- In infectious diseases: 257
- Year to date:
- Site-wide: 2,632
- Since beginning of last month:
- Site-wide: 6,029
Diagnosis of Acute Respiratory Syndrome Coronavirus 2 Infection by Detection of Nucleocapsid Protein
epidemiology more details view paper- Downloaded 13,904 times
- Download rankings, all-time:
- Site-wide: 910
- In epidemiology: 136
- Year to date:
- Site-wide: 11,647
- Since beginning of last month:
- Site-wide: 20,309
A Novel Triage Tool of Artificial Intelligence Assisted Diagnosis Aid System for Suspected COVID-19 pneumonia In Fever Clinics
emergency medicine more details view paper- Downloaded 3,223 times
- Download rankings, all-time:
- Site-wide: 6,606
- In emergency medicine: 9
- Year to date:
- Site-wide: 20,251
- Since beginning of last month:
- Site-wide: 39,639
Metabolite discovery through global annotation of untargeted metabolomics data
bioinformatics more details view paper- Downloaded 2,551 times
- Download rankings, all-time:
- Site-wide: 9,278
- In bioinformatics: 976
- Year to date:
- Site-wide: 39,153
- Since beginning of last month:
- Site-wide: 18,395
Critical Care for Patients with Severe Covid-2019 in Sichuan Province, China: Provincial Cohort Study
intensive care and critical care medicine more details view paper- Downloaded 2,280 times
- Download rankings, all-time:
- Site-wide: 11,020
- In intensive care and critical care medicine: 50
- Year to date:
- Site-wide: 17,182
- Since beginning of last month:
- Site-wide: 17,173
A two-enzyme adaptive unit within bacterial folate metabolism
systems biology more details view paper- Downloaded 1,768 times
- Download rankings, all-time:
- Site-wide: 16,249
- In systems biology: 258
- Year to date:
- Site-wide: 146,328
- Since beginning of last month:
- Site-wide: 90,528
GMPR: A novel normalization method for microbiome sequencing data
bioinformatics more details view paper- Downloaded 1,439 times
- Download rankings, all-time:
- Site-wide: 22,528
- In bioinformatics: 2,496
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 202,379
Gene flow between divergent cereal- and grass-specific lineages of the rice blast fungus Magnaporthe oryzae
microbiology more details view paper- Downloaded 1,390 times
- Download rankings, all-time:
- Site-wide: 23,812
- In microbiology: 1,374
- Year to date:
- Site-wide: 83,023
- Since beginning of last month:
- Site-wide: 145,580
Sympathetic Nerve Activity Promotes Cardiomyocyte Cell-Cycle Arrest And Binucleation
developmental biology more details view paper- Downloaded 1,288 times
- Download rankings, all-time:
- Site-wide: 26,935
- In developmental biology: 476
- Year to date:
- Site-wide: 84,997
- Since beginning of last month:
- Site-wide: 141,684
Base editing in Streptomyces with Cas9-deaminase fusions
microbiology more details view paper- Downloaded 1,264 times
- Download rankings, all-time:
- Site-wide: 27,688
- In microbiology: 1,647
- Year to date:
- Site-wide: 23,499
- Since beginning of last month:
- Site-wide: 21,529
Artificial Intelligence Assisted Early Warning System for Acute Kidney Injury Driven by Multi-Center ICU Database
intensive care and critical care medicine more details view paper- Downloaded 1,250 times
- Download rankings, all-time:
- Site-wide: 28,201
- In intensive care and critical care medicine: 94
- Year to date:
- Site-wide: 39,707
- Since beginning of last month:
- Site-wide: 34,179
MS-PyCloud: An open-source, cloud computing-based pipeline for LC-MS/MS data analysis
bioinformatics more details view paper- Downloaded 1,249 times
- Download rankings, all-time:
- Site-wide: 28,235
- In bioinformatics: 3,039
- Year to date:
- Site-wide: 116,414
- Since beginning of last month:
- Site-wide: 116,977
Longitudinal analysis of laboratory findings during the process of recovery for patients with COVID-19
infectious diseases more details view paper- Downloaded 1,171 times
- Download rankings, all-time:
- Site-wide: 31,261
- In infectious diseases: 2,916
- Year to date:
- Site-wide: 94,209
- Since beginning of last month:
- Site-wide: 124,941
Destin: toolkit for single-cell analysis of chromatin accessibility
bioinformatics more details view paper- Downloaded 1,146 times
- Download rankings, all-time:
- Site-wide: 32,340
- In bioinformatics: 3,418
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 200,468
Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines
bioinformatics more details view paper- Downloaded 1,090 times
- Download rankings, all-time:
- Site-wide: 34,880
- In bioinformatics: 3,701
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 81,153
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
cancer biology more details view paper- Downloaded 1,054 times
- Download rankings, all-time:
- Site-wide: 36,745
- In cancer biology: 995
- Year to date:
- Site-wide: 116,760
- Since beginning of last month:
- Site-wide: 164,396
Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord
neuroscience more details view paper- Downloaded 967 times
- Download rankings, all-time:
- Site-wide: 42,006
- In neuroscience: 5,467
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 129,126
The Metabolites NADP+ and NADPH are the Targets of the Circadian Protein Nocturnin (Curled)
biophysics more details view paper- Downloaded 843 times
- Download rankings, all-time:
- Site-wide: 51,892
- In biophysics: 1,658
- Year to date:
- Site-wide: 186,860
- Since beginning of last month:
- Site-wide: 200,041
Correlation of ELISA based with random access serologic immunoassays for identifying adaptive immune response to SARS-CoV-2
pathology more details view paper- Downloaded 831 times
- Download rankings, all-time:
- Site-wide: 53,013
- In pathology: 240
- Year to date:
- Site-wide: 133,389
- Since beginning of last month:
- Site-wide: 102,202
BAMM-SC: A Bayesian mixture model for clustering droplet-based single cell transcriptomic data from population studies
bioinformatics more details view paper- Downloaded 818 times
- Download rankings, all-time:
- Site-wide: 54,253
- In bioinformatics: 5,613
- Year to date:
- Site-wide: 5,899
- Since beginning of last month:
- Site-wide: 75,627
Multiplex Fragment Analysis Identifies SARS-CoV-2 Variants
epidemiology more details view paper- Downloaded 775 times
- Download rankings, all-time:
- Site-wide: 58,768
- In epidemiology: 2,833
- Year to date:
- Site-wide: 108,626
- Since beginning of last month:
- Site-wide: 31,311
Genomic analyses reveal the origin of domestic ducks and identify different genetic underpinnings of wild ducks
genomics more details view paper- Downloaded 748 times
- Download rankings, all-time:
- Site-wide: 61,984
- In genomics: 4,378
- Year to date:
- Site-wide: 36,923
- Since beginning of last month:
- Site-wide: 127,165
Tbx1 interacts genetically with Vegfr3 to regulate cardiac lymphangiogenesis in mice
developmental biology more details view paper- Downloaded 660 times
- Download rankings, all-time:
- Site-wide: 73,908
- In developmental biology: 1,819
- Year to date:
- Site-wide: 45,527
- Since beginning of last month:
- Site-wide: 145,142
Addressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via PROTAC-Mediated Degradation
biochemistry more details view paper- Downloaded 630 times
- Download rankings, all-time:
- Site-wide: 78,527
- In biochemistry: 2,153
- Year to date:
- Site-wide: 52,296
- Since beginning of last month:
- Site-wide: 31,016
DeepPHiC: Predicting promoter-centered chromatin interactions using a novel deep learning approach
bioinformatics more details view paper- Downloaded 600 times
- Download rankings, all-time:
- Site-wide: 83,504
- In bioinformatics: 7,756
- Year to date:
- Site-wide: 54,322
- Since beginning of last month:
- Site-wide: 18,921
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors
genomics more details view paper- Downloaded 597 times
- Download rankings, all-time:
- Site-wide: 84,152
- In genomics: 5,389
- Year to date:
- Site-wide: 162,943
- Since beginning of last month:
- Site-wide: 142,584
MiR-505-3p, a New Repressor of Puberty Onset in Female Mice
genetics more details view paper- Downloaded 591 times
- Download rankings, all-time:
- Site-wide: 85,237
- In genetics: 3,277
- Year to date:
- Site-wide: 82,504
- Since beginning of last month:
- Site-wide: 198,478
Interaction between DNA damage response, translation and apoptosome determines cancer susceptibility to TOP2 poisons
cancer biology more details view paper- Downloaded 584 times
- Download rankings, all-time:
- Site-wide: 86,575
- In cancer biology: 2,552
- Year to date:
- Site-wide: 82,772
- Since beginning of last month:
- Site-wide: 181,860
A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression
cancer biology more details view paper- Downloaded 572 times
- Download rankings, all-time:
- Site-wide: 88,858
- In cancer biology: 2,665
- Year to date:
- Site-wide: 98,265
- Since beginning of last month:
- Site-wide: 43,852
Toxicities of PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
oncology more details view paper- Downloaded 521 times
- Download rankings, all-time:
- Site-wide: 99,321
- In oncology: 237
- Year to date:
- Site-wide: 124,869
- Since beginning of last month:
- Site-wide: 100,785
Bacterial fucosidase enables the production of Bombay red blood cells
molecular biology more details view paper- Downloaded 513 times
- Download rankings, all-time:
- Site-wide: 101,292
- In molecular biology: 2,986
- Year to date:
- Site-wide: 80,124
- Since beginning of last month:
- Site-wide: 120,231
Genetic variation within the human papillomavirus type 16 genome is associated with oropharyngeal cancer prognosis
epidemiology more details view paper- Downloaded 488 times
- Download rankings, all-time:
- Site-wide: 107,016
- In epidemiology: 4,658
- Year to date:
- Site-wide: 18,903
- Since beginning of last month:
- Site-wide: 54,991
CD8+ T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomas
cancer biology more details view paper- Downloaded 487 times
- Download rankings, all-time:
- Site-wide: 107,201
- In cancer biology: 3,248
- Year to date:
- Site-wide: 151,206
- Since beginning of last month:
- Site-wide: 149,086
Transposon-mediated telomere destabilization: a driver of genome evolution in the blast fungus
genomics more details view paper- Downloaded 438 times
- Download rankings, all-time:
- Site-wide: 119,539
- In genomics: 6,772
- Year to date:
- Site-wide: 162,810
- Since beginning of last month:
- Site-wide: 211,468
Developmental and Intergenerational Landscape of Human Circulatory Lipidome and its Association with Obesity Risk
systems biology more details view paper- Downloaded 434 times
- Download rankings, all-time:
- Site-wide: 120,475
- In systems biology: 2,463
- Year to date:
- Site-wide: 138,705
- Since beginning of last month:
- Site-wide: 63,096
Venom Isosolenopsin A Delivers Rapid Knockdown of Fire Ant Competitors
zoology more details view paper- Downloaded 431 times
- Download rankings, all-time:
- Site-wide: 121,366
- In zoology: 426
- Year to date:
- Site-wide: 161,548
- Since beginning of last month:
- Site-wide: 179,722
FER-mediated tyrosine phosphorylation and PIK3R2/p85β recruitment on IRS4 promotes the PI3K-AKT signaling pathway and tumorigenesis in ovarian cancer
molecular biology more details view paper- Downloaded 424 times
- Download rankings, all-time:
- Site-wide: 123,252
- In molecular biology: 3,640
- Year to date:
- Site-wide: 64,493
- Since beginning of last month:
- Site-wide: 129,677
DeepPerVar: a multimodal deep learning framework for functional interpretation of genetic variants in personal genome
bioinformatics more details view paper- Downloaded 423 times
- Download rankings, all-time:
- Site-wide: 123,332
- In bioinformatics: 10,509
- Year to date:
- Site-wide: 12,087
- Since beginning of last month:
- Site-wide: 23,136
A Short Plus Long-Amplicon Based Sequencing Approach Improves Genomic Coverage and Variant Detection In the SARS-CoV-2 Genome
genetic and genomic medicine more details view paper- Downloaded 413 times
- Download rankings, all-time:
- Site-wide: 126,277
- In genetic and genomic medicine: 881
- Year to date:
- Site-wide: 42,845
- Since beginning of last month:
- Site-wide: 85,666
Exploiting deep transfer learning for the prediction of functional noncoding variants using genomic sequence
bioinformatics more details view paper- Downloaded 413 times
- Download rankings, all-time:
- Site-wide: 126,336
- In bioinformatics: 11,488
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 19,143
CRISPR-Cas9 Screen Reveals PSMB3 Contributes to Gliomagenesis Through Proteasome-Dependent and Independent Mechanisms
cancer biology more details view paper- Downloaded 401 times
- Download rankings, all-time:
- Site-wide: 129,611
- In cancer biology: 4,063
- Year to date:
- Site-wide: 51,921
- Since beginning of last month:
- Site-wide: 33,699
WEVar: a novel statistical learning framework for predicting noncoding regulatory variants
bioinformatics more details view paper- Downloaded 371 times
- Download rankings, all-time:
- Site-wide: 138,421
- In bioinformatics: 11,108
- Year to date:
- Site-wide: 92,603
- Since beginning of last month:
- Site-wide: 101,018
Exploring differentially expressed key genes related to development of follicle by RNA-seq in Peking ducks (Anas Platyrhynchos)
developmental biology more details view paper- Downloaded 335 times
- Download rankings, all-time:
- Site-wide: 149,554
- In developmental biology: 3,975
- Year to date:
- Site-wide: 147,845
- Since beginning of last month:
- Site-wide: 180,084
A missense mutation of Ip3r1 in Dp2 mice leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles
genetics more details view paper- Downloaded 313 times
- Download rankings, all-time:
- Site-wide: 155,855
- In genetics: 5,749
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 179,894
Crif1 Promotes Osteoporosis in Mice after Radiation
cell biology more details view paper- Downloaded 310 times
- Download rankings, all-time:
- Site-wide: 156,764
- In cell biology: 7,295
- Year to date:
- Site-wide: 188,303
- Since beginning of last month:
- Site-wide: 206,621
Interleukin-33 stimulates stress in the endoplasmic reticulum of the human myometrium via an influx of calcium during initiation of labor
obstetrics and gynecology more details view paper- Downloaded 277 times
- Download rankings, all-time:
- Site-wide: 166,817
- In obstetrics and gynecology: 238
- Year to date:
- Site-wide: 106,173
- Since beginning of last month:
- Site-wide: 97,703
Understanding community level influences on COVID-19 prevalence in England: New insights from comparison over time and space
health informatics more details view paper- Downloaded 273 times
- Download rankings, all-time:
- Site-wide: 167,918
- In health informatics: 794
- Year to date:
- Site-wide: 141,765
- Since beginning of last month:
- Site-wide: 107,175
Berberine alleviates adiposity and cardiac dysfunction in offspring exposed to gestational diabetes mellitus
physiology more details view paper- Downloaded 259 times
- Download rankings, all-time:
- Site-wide: 172,174
- In physiology: 1,909
- Year to date:
- Site-wide: 134,286
- Since beginning of last month:
- Site-wide: 80,870
Pre-clinical Research of Human Amnion-derived Mesenchymal Stem Cells and its First Clinical Treatment for a Severe Uremic Calciphylaxis Patient
nephrology more details view paper- Downloaded 248 times
- Download rankings, all-time:
- Site-wide: 175,154
- In nephrology: 152
- Year to date:
- Site-wide: 139,465
- Since beginning of last month:
- Site-wide: 111,239
THEMIS is a priming substrate of non-receptor tyrosine phosphatase PTPN6/SHP1 and plays dual roles during T cell development
cell biology more details view paper- Downloaded 245 times
- Download rankings, all-time:
- Site-wide: 176,009
- In cell biology: 8,184
- Year to date:
- Site-wide: 178,919
- Since beginning of last month:
- Site-wide: 88,525
Ontogeny of plasma lipid metabolism in pregnancy and early childhood: a longitudinal population study
epidemiology more details view paper- Downloaded 238 times
- Download rankings, all-time:
- Site-wide: 177,758
- In epidemiology: 7,112
- Year to date:
- Site-wide: 97,904
- Since beginning of last month:
- Site-wide: 111,918
Increased ketohexokinase-A governs fructose-induced podocyte hypertrophy by IL-6/STAT3 signaling activation
pathology more details view paper- Downloaded 221 times
- Download rankings, all-time:
- Site-wide: 182,324
- In pathology: 1,072
- Year to date:
- Site-wide: 171,324
- Since beginning of last month:
- Site-wide: 95,515
ARF4-mediated Retrograde Trafficking Drives Chemoresistance in Glioblastoma
cancer biology more details view paper- Downloaded 216 times
- Download rankings, all-time:
- Site-wide: 183,674
- In cancer biology: 5,732
- Year to date:
- Site-wide: 57,252
- Since beginning of last month:
- Site-wide: 99,350
Multi-task deep autoencoder to predict Alzheimer's disease progression using temporal DNA methylation data in peripheral blood
genetic and genomic medicine more details view paper- Downloaded 200 times
- Download rankings, all-time:
- Site-wide: 187,465
- In genetic and genomic medicine: 1,405
- Year to date:
- Site-wide: 141,377
- Since beginning of last month:
- Site-wide: 109,258
New efficient intercellular spread mode of respiratory syncytial virus contributes to neutralization escape and persistence
microbiology more details view paper- Downloaded 176 times
- Download rankings, all-time:
- Site-wide: 192,906
- In microbiology: 14,650
- Year to date:
- Site-wide: 57,295
- Since beginning of last month:
- Site-wide: 167,716
Differential N-terminal processing of beta and gamma actin in vivo
cell biology more details view paper- Downloaded 149 times
- Download rankings, all-time:
- Site-wide: 198,463
- In cell biology: 9,114
- Year to date:
- Site-wide: 143,471
- Since beginning of last month:
- Site-wide: 158,041
Proliferative Exhausted CD8 T Cells Exacerbate Long-lasting Anti-tumor Effects in Human Papillomavirus Positive Head and Neck Squamous Cell Carcinoma
immunology more details view paper- Downloaded 123 times
- Download rankings, all-time:
- Site-wide: 203,298
- In immunology: 6,555
- Year to date:
- Site-wide: 58,805
- Since beginning of last month:
- Site-wide: 46,732
Genome-wide identification and gene expression analysis of clade A protein phosphatase 2C family genes in Brassica juncea var. tumida
bioinformatics more details view paper- Downloaded 118 times
- Download rankings, all-time:
- Site-wide: 204,122
- In bioinformatics: 14,890
- Year to date:
- Site-wide: 174,421
- Since beginning of last month:
- Site-wide: 113,503
TIVAN-indel: A computational framework for annotating and predicting noncoding regulatory small insertion and deletion
bioinformatics more details view paper- Downloaded 75 times
- Download rankings, all-time:
- Site-wide: 212,093
- In bioinformatics: 15,321
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 195,196
PanLingua
News
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
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- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!