Author: Jie Xu

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Preprints

An Integrative Framework For Detecting Structural Variations In Cancer Genomes

• Downloaded 4,176 times
• Download rankings, all-time:
  • Site-wide: 3,043
  • In genomics: 313
• Year to date:
  • Site-wide: 82,197
• Since beginning of last month:
  • Site-wide: 72,443

Optimizing diagnostic strategy for novel coronavirus pneumonia, a multi-center study in Eastern China

• Downloaded 4,116 times
• Download rankings, all-time:
  • Site-wide: 3,107
  • In infectious diseases: 664
• Year to date:
  • Site-wide: 15,300
• Since beginning of last month:
  • Site-wide: 107,862

Trends and prediction in daily incidence of novel coronavirus infection in China, Hubei Province and Wuhan City: an application of Farr law

• Downloaded 3,100 times
• Download rankings, all-time:
  • Site-wide: 4,615
  • In epidemiology: 432
• Year to date:
  • Site-wide: 25,111
• Since beginning of last month:
  • Site-wide: 46,260

A descriptive study of the impact of diseases control and prevention on the epidemics dynamics and clinical features of SARS-CoV-2 outbreak in Shanghai, lessons learned for metropolis epidemics prevention

• Downloaded 3,093 times
• Download rankings, all-time:
  • Site-wide: 4,632
  • In infectious diseases: 861
• Year to date:
  • Site-wide: 27,187
• Since beginning of last month:
  • Site-wide: 32,593

Heart injury signs are associated with higher and earlier mortality in coronavirus disease 2019 (COVID-19)

• Downloaded 3,060 times
• Download rankings, all-time:
  • Site-wide: 4,693
  • In respiratory medicine: 20
• Year to date:
  • Site-wide: 24,698
• Since beginning of last month:
  • Site-wide: 21,139

The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions

• Downloaded 3,005 times
• Download rankings, all-time:
  • Site-wide: 4,814
  • In bioinformatics: 473
• Year to date:
  • Site-wide: 55,966
• Since beginning of last month:
  • Site-wide: 3,536

Prevalence and clinical features of 2019 novel coronavirus disease (COVID-19) in the Fever Clinic of a teaching hospital in Beijing: a single-center, retrospective study

• Downloaded 2,847 times
• Download rankings, all-time:
  • Site-wide: 5,206
  • In respiratory medicine: 24
• Year to date:
  • Site-wide: 28,319
• Since beginning of last month:
  • Site-wide: 107,571

Associations of stay-at-home order and face-masking recommendation with trends in daily new cases and deaths of laboratory-confirmed COVID-19 in the United States

• Downloaded 1,733 times
• Download rankings, all-time:
  • Site-wide: 10,812
  • In epidemiology: 797
• Year to date:
  • Site-wide: 51,887
• Since beginning of last month:
  • Site-wide: 33,016

An Integrated Framework for Genome Analysis Reveals Numerous Previously Unrecognizable Structural Variants in Leukemia Patients' Samples

• Downloaded 1,586 times
• Download rankings, all-time:
  • Site-wide: 12,287
  • In genomics: 1,265
• Year to date:
  • Site-wide: 23,563
• Since beginning of last month:
  • Site-wide: 40,068

An integrative ENCODE resource for cancer genomics

• Downloaded 1,344 times
• Download rankings, all-time:
  • Site-wide: 15,763
  • In genomics: 1,570
• Year to date:
  • Site-wide: 69,492
• Since beginning of last month:
  • Site-wide: 87,565

Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence

• Downloaded 1,273 times
• Download rankings, all-time:
  • Site-wide: 17,128
  • In microbiology: 1,004
• Year to date:
  • Site-wide: 75,835
• Since beginning of last month:
  • Site-wide: None

Cryo-EM structure of the receptor-activated TRPC5 ion channel at 2.9 angstrom resolution

• Downloaded 1,141 times
• Download rankings, all-time:
  • Site-wide: 20,129
  • In biophysics: 513
• Year to date:
  • Site-wide: 117,462
• Since beginning of last month:
  • Site-wide: 81,796

Trends and prediction in daily incidence and deaths of COVID-19 in the United States: a search-interest based model

• Downloaded 1,097 times
• Download rankings, all-time:
  • Site-wide: 21,316
  • In epidemiology: 1,287
• Year to date:
  • Site-wide: 67,378
• Since beginning of last month:
  • Site-wide: 32,849

Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia

• Downloaded 973 times
• Download rankings, all-time:
  • Site-wide: 25,408
  • In cancer biology: 622
• Year to date:
  • Site-wide: 24,319
• Since beginning of last month:
  • Site-wide: 12,971

Palmitoylation is critically required for cancer intrinsic PD-1 expression and functions

• Downloaded 934 times
• Download rankings, all-time:
  • Site-wide: 26,971
  • In cancer biology: 669
• Year to date:
  • Site-wide: 51,432
• Since beginning of last month:
  • Site-wide: None

Subtype-specific epigenomic landscape and 3D genome structure in bladder cancer

• Downloaded 878 times
• Download rankings, all-time:
  • Site-wide: 29,382
  • In genomics: 2,616
• Year to date:
  • Site-wide: 37,105
• Since beginning of last month:
  • Site-wide: 95,910

Federated Learning of Electronic Health Records Improves Mortality Prediction in Patients Hospitalized with COVID-19

• Downloaded 859 times
• Download rankings, all-time:
  • Site-wide: 30,344
  • In health informatics: 130
• Year to date:
  • Site-wide: 19,354
• Since beginning of last month:
  • Site-wide: 11,389

Metabolomics and proteomics analyses of grain yield reduction in rice under abrupt drought-flood alternation

• Downloaded 726 times
• Download rankings, all-time:
  • Site-wide: 38,332
  • In plant biology: 771
• Year to date:
  • Site-wide: 83,267
• Since beginning of last month:
  • Site-wide: 78,985

Genome-wide co-localization of RNA-DNA interactions and fusion RNA pairs

• Downloaded 674 times
• Download rankings, all-time:
  • Site-wide: 42,265
  • In genomics: 3,408
• Year to date:
  • Site-wide: 105,960
• Since beginning of last month:
  • Site-wide: 81,917

Increased green autofluorescence is a marker for non-invasive prediction of H2O2-induced cell death and decreases in the intracellular ATP of HaCaT cells

• Downloaded 620 times
• Download rankings, all-time:
  • Site-wide: 47,079
  • In cell biology: 1,978
• Year to date:
  • Site-wide: 59,660
• Since beginning of last month:
  • Site-wide: None

Detecting Large Indels Using Optical Map Data

• Downloaded 490 times
• Download rankings, all-time:
  • Site-wide: 62,465
  • In bioinformatics: 6,157
• Year to date:
  • Site-wide: 118,663
• Since beginning of last month:
  • Site-wide: 71,079

Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM

• Downloaded 468 times
• Download rankings, all-time:
  • Site-wide: 65,684
  • In biophysics: 2,283
• Year to date:
  • Site-wide: 9,424
• Since beginning of last month:
  • Site-wide: 36,371

Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity

• Downloaded 376 times
• Download rankings, all-time:
  • Site-wide: 81,475
  • In cancer biology: 2,393
• Year to date:
  • Site-wide: 44,461
• Since beginning of last month:
  • Site-wide: 70,193

HIFα regulates developmental myelination independent of autocrine Wnt signaling

• Downloaded 359 times
• Download rankings, all-time:
  • Site-wide: 84,817
  • In neuroscience: 12,861
• Year to date:
  • Site-wide: 41,089
• Since beginning of last month:
  • Site-wide: 8,202

Diversity and complexity of the large surface protein family in the compacted genomes of various Pneumocystis species

• Downloaded 329 times
• Download rankings, all-time:
  • Site-wide: 91,155
  • In molecular biology: 2,654
• Year to date:
  • Site-wide: 120,995
• Since beginning of last month:
  • Site-wide: None

State heterogeneity of human mobility and COVID-19 epidemics in the European Union

• Downloaded 301 times
• Download rankings, all-time:
  • Site-wide: 97,500
  • In epidemiology: 4,095
• Year to date:
  • Site-wide: 80,545
• Since beginning of last month:
  • Site-wide: None

Genomic insights into the host specific adaptation of the Pneumocystis genus and emergence of the human pathogen Pneumocystis jirovecii

• Downloaded 266 times
• Download rankings, all-time:
  • Site-wide: 105,660
  • In evolutionary biology: 5,384
• Year to date:
  • Site-wide: 67,107
• Since beginning of last month:
  • Site-wide: 116,283

Role of PARP1 in oligodendrocyte differentiation during developmental myelination and remyelination after myelin damage

• Downloaded 225 times
• Download rankings, all-time:
  • Site-wide: 115,792
  • In neuroscience: 17,717
• Year to date:
  • Site-wide: 26,104
• Since beginning of last month:
  • Site-wide: 36,500

Lateral mechanical impedance rather than frontal, promotes cortical expansion of roots

• Downloaded 205 times
• Download rankings, all-time:
  • Site-wide: 120,821
  • In plant biology: 3,343
• Year to date:
  • Site-wide: 102,745
• Since beginning of last month:
  • Site-wide: None

Machine learning enabled subgroup analysis with real-world data to inform better clinical trial design

• Downloaded 169 times
• Download rankings, all-time:
  • Site-wide: 129,371
  • In health informatics: 526
• Year to date:
  • Site-wide: 36,807
• Since beginning of last month:
  • Site-wide: 36,802

Class II LBD genes ZmLBD5 and ZmLBD33 regulate gibberellin and abscisic acid biosynthesis

• Downloaded 140 times
• Download rankings, all-time:
  • Site-wide: 135,861
  • In plant biology: 3,800
• Year to date:
  • Site-wide: 45,389
• Since beginning of last month:
  • Site-wide: None

Proteasome maturation factor UMP1 confers broad-spectrum disease resistance by modulating H2O2 accumulation in rice

• Downloaded 125 times
• Download rankings, all-time:
  • Site-wide: 139,101
  • In plant biology: 3,898
• Year to date:
  • Site-wide: 51,049
• Since beginning of last month:
  • Site-wide: 115,182

Nasal BCG Exposure Accelerates Dural Lymphatics Development via Macrophages' Role in Newborn Mice

• Downloaded 107 times
• Download rankings, all-time:
  • Site-wide: 142,466
  • In neuroscience: 21,547
• Year to date:
  • Site-wide: 59,257
• Since beginning of last month:
  • Site-wide: None

Dual functions of ZmGI1 in the photoperiodic flowering pathway and salt stress responses in maize

• Downloaded 92 times
• Download rankings, all-time:
  • Site-wide: 145,098
  • In developmental biology: 3,814
• Year to date:
  • Site-wide: 67,905
• Since beginning of last month:
  • Site-wide: 108,431

Development of a federated learning approach to predict acute kidney injury in adult hospitalized patients with COVID-19 in New York City

• Downloaded 18 times
• Download rankings, all-time:
  • Site-wide: 151,797
  • In nephrology: 110
• Year to date:
  • Site-wide: 149,649
• Since beginning of last month:
  • Site-wide: 20,145

Comparative genomic and pan-genomic characteristion of Staphylococcus epidermidis from different sources unveils the molecular basis and potential biomarkers of pathogenic strains

• Downloaded 12 times
• Download rankings, all-time:
  • Site-wide: 152,287
  • In microbiology: 11,921
• Year to date:
  • Site-wide: 152,014
• Since beginning of last month:
  • Site-wide: 6,237

Asymmetrical adaptations to increases and decreases in environmental volatility

• Downloaded 1 times
• Download rankings, all-time:
  • Site-wide: 154,516
  • In neuroscience: 23,083
• Year to date:
  • Site-wide: 154,529
• Since beginning of last month:
  • Site-wide: 54,684