Author: Kai Wang

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Preprints

A computational tool for direct inference of cell-specific expression profiles and cellular composition from bulk-tissue RNA-seq in brain disorders

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Cell type-specific proteogenomic signal diffusion for integrating multi-omics data predicts novel schizophrenia risk genes

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Observing the Cell in Its Native State: Imaging Subcellular Dynamics in Multicellular Organisms

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Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio)

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N6-Methyladenine DNA Modification in Human Genome

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NextSV: a meta-caller for structural variants from low-coverage long-read sequencing data

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A variant in TAF1 is associated with a new syndrome with severe intellectual disability and characteristic dysmorphic features

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NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data

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Isolation and characterization of extracellular vesicles from Caenorhabditis elegans for multi-omic analysis.

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Deconvolution of Transcriptional Networks Identifies TCF4 as a Master Regulator in Schizophrenia

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Reduced Default Mode Network Functional Connectivity in Patients with Recurrent Major Depressive Disorder

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VirTect: a computational method for detecting virus species from RNA-Seq and its application in head and neck squamous cell carcinoma

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Single-molecule optical mapping enables quantitative measurement of D4Z4 repeats in facioscapulohumeral muscular dystrophy (FSHD)

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Detection of Base Analogs Incorporated During DNA Replication by Nanopore Sequencing

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Molecular and cellular phenotypic differences distinguish murine syngeneic models from human tumors

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Localization of balanced chromosome translocation breakpoints by long-read sequencing on the Oxford Nanopore platform

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LinkedSV for detection of mosaic structural variants from linked-read exome and genome sequencing data

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iCAGES: integrated CAncer GEnome Score for comprehensively prioritizing cancer driver genes in personal genomes

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Assessing the measurement transfer function of single-cell RNA sequencing

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HadoopCNV: A Dynamic Programming Imputation Algorithm To Detect Copy Number Variants From Sequencing Data

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Capturing volumetric dynamics at high speed in the brain by confocal light field microscopy

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TNER: A Novel Background Error Suppression Method for Mutation Detection in Circulating Tumor DNA

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NanoCaller for accurate detection of SNPs and small indels from long-read sequencing by deep neural networks

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Oligomerization of the NLR immune receptor RPP7 triggered by the atypical resistance protein RPW8/HR as a ligand

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Detecting differential alternative splicing events in scRNA-seq with or without UMIs

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Constitutive activation of leucine-rich repeat receptor kinase signaling pathways by BAK1-interacting receptor-like kinase 3 chimera

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Long-read sequencing identified a causal structural variant in an exome-negative case and enabled preimplantation genetic diagnosis

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UBE2G1 Governs the Destruction of Cereblon Neomorphic Substrates

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Gene expression in patient-derived neural progenitors implicates WNT5A signaling in the etiology of schizophrenia

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Ligation-anchored PCR unveils immune repertoire of TCR-beta from whole blood

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Phen2Gene: Rapid Phenotype-Driven Gene Prioritization for Rare Diseases

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ADAMTS-family protease MIG-17 regulates synaptic allometry by modifying the extracellular matrix and modulating glia morphology during growth

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Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

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Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1

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Genome-wide selection footprints and deleterious variations in young Asian allotetraploid rapeseed

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Mechanistic insights on metabolic dysfunction in PTSD: Role of glucocorticoid receptor sensitivity and energy deficit

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MicroRNA-transcriptome networks in whole blood and monocytes of women undergoing preterm labor

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DNA demethylation is a driver for chick retina regeneration

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PSC-RED, an Albumin-Free Robust Erythroid Differentiation Method to Produce Enucleated Red Blood Cells from Human Pluripotent Stem Cells

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A novel phyllosphere resident Protomyces species that interacts with the Arabidopsis immune system

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Characterizing the Cancer-Associated Microbiome with Small RNA Sequencing Data

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Transcriptional Network Analysis on Brains Reveals a Potential Regulatory Role of PPP1R3F in Autism Spectrum Disorders

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Implications of error-prone long-read whole-genome shotgun sequencing on characterizing reference microbiomes

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Temporal Small RNA Expression Profiling Under Drought Reveals a Potential Regulatory Role of snoRNAs in Drought Responses of Maize

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Temporal regulation of prenatal embryonic development by paternal imprinted loci

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MNC-RED a Chemically Defined Method to Produce Enucleated Red Blood Cells from Adult Peripheral Blood Mononuclear Cells

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Epidemiology, Microbiology and Therapeutic Consequences of Chronic Osteomyelitis in Northern China: A Retrospective Analysis of 255 Patients

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The CDK inhibitor SIAMESE targets both CDKA;1 and CDKB1 complexes to establish endoreplication in trichomes

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A novel Arabidopsis phyllosphere resident Protomyces sp. and a re-examination of genus Protomyces based on genome sequence data.

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O-GlcNAcylation of SAMHD1 Indicating a Link between Metabolic Reprogramming and Anti-HBV Immunity

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