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Author: Kai Wang

Rankings

  • All-time downloads: 104,251 (rank: 890 )
  • Categories:
    • animal behavior and cognition: 118 (rank: 6,057 (tie) )
    • bioengineering: 641 (rank: 4,836 (tie) )
    • bioinformatics: 12,485 (rank: 472 )
    • cancer biology: 2,217 (rank: 1,957 (tie) )
    • cell biology: 15,746 (rank: 21 )
    • developmental biology: 633 (rank: 6,186 (tie) )
    • epidemiology: 5,915 (rank: 1,756 (tie) )
    • genetics: 5,493 (rank: 3,381 (tie) )
    • genomics: 11,842 (rank: 1,378 )
    • immunology: 3,108 (rank: 2,027 (tie) )
    • infectious diseases: 23,872 (rank: 1,898 )
    • microbiology: 8,992 (rank: 1,299 )
    • molecular biology: 733 (rank: 7,217 (tie) )
    • neuroscience: 8,584 (rank: 1,372 )
    • pediatrics: 235 (rank: 942 (tie) )
    • plant biology: 2,236 (rank: 929 (tie) )
    • systems biology: 1,401 (rank: 2,691 (tie) )

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Preprints

Deficiency of gluconeogenic enzyme PCK1 promotes non-alcoholic steatohepatitis progression by activation of PI3K/AKT/PDGF axis

molecular biology more details view paper

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Recombinant adenovirus causes prolonged mobilization of macrophages in the anterior chamber of mice

physiology more details view paper

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Reinfection with SARS-CoV-2 and Failure of Humoral Immunity: a case report.

infectious diseases more details view paper
  • Downloaded 20,192 times
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    • Site-wide: 297
    • In infectious diseases: 116
  • Year to date:
    • Site-wide: 286
  • Since beginning of last month:
    • Site-wide: 212

Observing the Cell in Its Native State: Imaging Subcellular Dynamics in Multicellular Organisms

cell biology more details view paper
  • Downloaded 13,077 times
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    • Site-wide: 467
    • In cell biology: 2
  • Year to date:
    • Site-wide: 45,116
  • Since beginning of last month:
    • Site-wide: 84,721

The D614G mutation of SARS-CoV-2 spike protein enhances viral infectivity

microbiology more details view paper
  • Downloaded 7,849 times
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    • Site-wide: 950
    • In microbiology: 91
  • Year to date:
    • Site-wide: 1,012
  • Since beginning of last month:
    • Site-wide: 873

Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio)

neuroscience more details view paper
  • Downloaded 3,515 times
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    • Site-wide: 2,875
    • In neuroscience: 230
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    • Site-wide: 31,494
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    • Site-wide: 65,401

Modelling the coronavirus disease (COVID-19) outbreak on the Diamond Princess ship using the public surveillance data from January 20 to February 20, 2020

epidemiology more details view paper
  • Downloaded 3,307 times
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    • Site-wide: 3,155
    • In epidemiology: 299
  • Year to date:
    • Site-wide: 5,746
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    • Site-wide: 8,515

Estimating the serial interval of the novel coronavirus disease (COVID-19): A statistical analysis using the public data in Hong Kong from January 16 to February 15, 2020

epidemiology more details view paper
  • Downloaded 2,608 times
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    • Site-wide: 4,432
    • In epidemiology: 386
  • Year to date:
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    • Site-wide: 31,656

NextSV: a meta-caller for structural variants from low-coverage long-read sequencing data

genomics more details view paper
  • Downloaded 2,457 times
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    • Site-wide: 4,832
    • In genomics: 587
  • Year to date:
    • Site-wide: 29,359
  • Since beginning of last month:
    • Site-wide: 46,552

N6-Methyladenine DNA Modification in Human Genome

genomics more details view paper
  • Downloaded 2,448 times
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    • Site-wide: 4,864
    • In genomics: 591
  • Year to date:
    • Site-wide: 41,258
  • Since beginning of last month:
    • Site-wide: 31,245

Infectivity, susceptibility, and risk factors associated with SARS-CoV-2 transmission under intensive contact tracing in Hunan, China

infectious diseases more details view paper
  • Downloaded 2,349 times
  • Download rankings, all-time:
    • Site-wide: 5,182
    • In infectious diseases: 764
  • Year to date:
    • Site-wide: 4,433
  • Since beginning of last month:
    • Site-wide: 2,098

A variant in TAF1 is associated with a new syndrome with severe intellectual disability and characteristic dysmorphic features

genetics more details view paper
  • Downloaded 2,306 times
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    • Site-wide: 5,333
    • In genetics: 262
  • Year to date:
    • Site-wide: 45,105
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    • Site-wide: 42,741

NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data

bioinformatics more details view paper
  • Downloaded 2,219 times
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    • Site-wide: 5,641
    • In bioinformatics: 685
  • Year to date:
    • Site-wide: 74,686
  • Since beginning of last month:
    • Site-wide: 121,144

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories

immunology more details view paper
  • Downloaded 2,144 times
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    • Site-wide: 5,896
    • In immunology: 152
  • Year to date:
    • Site-wide: 3,829
  • Since beginning of last month:
    • Site-wide: 3,934

Isolation and characterization of extracellular vesicles from Caenorhabditis elegans for multi-omic analysis.

cell biology more details view paper
  • Downloaded 2,021 times
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    • Site-wide: 6,447
    • In cell biology: 135
  • Year to date:
    • Site-wide: 23,909
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    • Site-wide: 15,990

NanoCaller for accurate detection of SNPs and indels in difficult-to-map regions from long-read sequencing by haplotype-aware deep neural networks

bioinformatics more details view paper
  • Downloaded 1,910 times
  • Download rankings, all-time:
    • Site-wide: 7,001
    • In bioinformatics: 891
  • Year to date:
    • Site-wide: 6,235
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    • Site-wide: 4,226

Reduced Default Mode Network Functional Connectivity in Patients with Recurrent Major Depressive Disorder

neuroscience more details view paper
  • Downloaded 1,585 times
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    • Site-wide: 9,298
    • In neuroscience: 1,033
  • Year to date:
    • Site-wide: 12,151
  • Since beginning of last month:
    • Site-wide: 22,873

Deconvolution of Transcriptional Networks Identifies TCF4 as a Master Regulator in Schizophrenia

neuroscience more details view paper
  • Downloaded 1,575 times
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    • Site-wide: 9,382
    • In neuroscience: 1,045
  • Year to date:
    • Site-wide: 34,237
  • Since beginning of last month:
    • Site-wide: 78,641

Molecular and cellular phenotypic differences distinguish murine syngeneic models from human tumors

cancer biology more details view paper
  • Downloaded 1,497 times
  • Download rankings, all-time:
    • Site-wide: 10,103
    • In cancer biology: 200
  • Year to date:
    • Site-wide: 26,187
  • Since beginning of last month:
    • Site-wide: 20,585

Detection of Base Analogs Incorporated During DNA Replication by Nanopore Sequencing

genomics more details view paper
  • Downloaded 1,442 times
  • Download rankings, all-time:
    • Site-wide: 10,668
    • In genomics: 1,215
  • Year to date:
    • Site-wide: 55,658
  • Since beginning of last month:
    • Site-wide: 101,988

VirTect: a computational method for detecting virus species from RNA-Seq and its application in head and neck squamous cell carcinoma

bioinformatics more details view paper
  • Downloaded 1,422 times
  • Download rankings, all-time:
    • Site-wide: 10,917
    • In bioinformatics: 1,389
  • Year to date:
    • Site-wide: 62,559
  • Since beginning of last month:
    • Site-wide: 49,689

Single-molecule optical mapping enables quantitative measurement of D4Z4 repeats in facioscapulohumeral muscular dystrophy (FSHD)

genomics more details view paper
  • Downloaded 1,414 times
  • Download rankings, all-time:
    • Site-wide: 10,994
    • In genomics: 1,248
  • Year to date:
    • Site-wide: 27,048
  • Since beginning of last month:
    • Site-wide: 52,203

Capturing volumetric dynamics at high speed in the brain by confocal light field microscopy

neuroscience more details view paper
  • Downloaded 1,305 times
  • Download rankings, all-time:
    • Site-wide: 12,415
    • In neuroscience: 1,479
  • Year to date:
    • Site-wide: 56,383
  • Since beginning of last month:
    • Site-wide: 59,700

Localization of balanced chromosome translocation breakpoints by long-read sequencing on the Oxford Nanopore platform

genetics more details view paper
  • Downloaded 1,293 times
  • Download rankings, all-time:
    • Site-wide: 12,587
    • In genetics: 648
  • Year to date:
    • Site-wide: 50,719
  • Since beginning of last month:
    • Site-wide: 20,339

LinkedSV for detection of mosaic structural variants from linked-read exome and genome sequencing data

bioinformatics more details view paper
  • Downloaded 1,217 times
  • Download rankings, all-time:
    • Site-wide: 13,820
    • In bioinformatics: 1,738
  • Year to date:
    • Site-wide: 116,076
  • Since beginning of last month:
    • Site-wide: 64,266

HadoopCNV: A Dynamic Programming Imputation Algorithm To Detect Copy Number Variants From Sequencing Data

bioinformatics more details view paper
  • Downloaded 1,148 times
  • Download rankings, all-time:
    • Site-wide: 15,048
    • In bioinformatics: 1,889
  • Year to date:
    • Site-wide: 83,581
  • Since beginning of last month:
    • Site-wide: 80,939

iCAGES: integrated CAncer GEnome Score for comprehensively prioritizing cancer driver genes in personal genomes

genomics more details view paper
  • Downloaded 1,136 times
  • Download rankings, all-time:
    • Site-wide: 15,275
    • In genomics: 1,659
  • Year to date:
    • Site-wide: 51,463
  • Since beginning of last month:
    • Site-wide: 52,519

TNER: A Novel Background Error Suppression Method for Mutation Detection in Circulating Tumor DNA

bioinformatics more details view paper
  • Downloaded 1,103 times
  • Download rankings, all-time:
    • Site-wide: 16,011
    • In bioinformatics: 1,998
  • Year to date:
    • Site-wide: 44,328
  • Since beginning of last month:
    • Site-wide: 58,263

Assessing the measurement transfer function of single-cell RNA sequencing

genomics more details view paper
  • Downloaded 1,094 times
  • Download rankings, all-time:
    • Site-wide: 16,211
    • In genomics: 1,726
  • Year to date:
    • Site-wide: 100,190
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    • Site-wide: 100,372

Detecting differential alternative splicing events in scRNA-seq with or without UMIs

bioinformatics more details view paper
  • Downloaded 1,008 times
  • Download rankings, all-time:
    • Site-wide: 18,350
    • In bioinformatics: 2,272
  • Year to date:
    • Site-wide: 24,222
  • Since beginning of last month:
    • Site-wide: 44,314

precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions

bioinformatics more details view paper
  • Downloaded 997 times
  • Download rankings, all-time:
    • Site-wide: 18,642
    • In bioinformatics: 2,313
  • Year to date:
    • Site-wide: 2,030
  • Since beginning of last month:
    • Site-wide: 1,314

Oligomerization of the NLR immune receptor RPP7 triggered by the atypical resistance protein RPW8/HR as a ligand

plant biology more details view paper
  • Downloaded 967 times
  • Download rankings, all-time:
    • Site-wide: 19,476
    • In plant biology: 318
  • Year to date:
    • Site-wide: 20,232
  • Since beginning of last month:
    • Site-wide: 74,170

Constitutive activation of leucine-rich repeat receptor kinase signaling pathways by BAK1-interacting receptor-like kinase 3 chimera

plant biology more details view paper
  • Downloaded 822 times
  • Download rankings, all-time:
    • Site-wide: 24,618
    • In plant biology: 436
  • Year to date:
    • Site-wide: 37,141
  • Since beginning of last month:
    • Site-wide: 36,078

Gene expression in patient-derived neural progenitors implicates WNT5A signaling in the etiology of schizophrenia

genetics more details view paper
  • Downloaded 741 times
  • Download rankings, all-time:
    • Site-wide: 28,414
    • In genetics: 1,434
  • Year to date:
    • Site-wide: 103,201
  • Since beginning of last month:
    • Site-wide: 39,087

UBE2G1 Governs the Destruction of Cereblon Neomorphic Substrates

molecular biology more details view paper
  • Downloaded 733 times
  • Download rankings, all-time:
    • Site-wide: 28,854
    • In molecular biology: 824
  • Year to date:
    • Site-wide: 54,570
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    • Site-wide: 44,484

Long-read sequencing identified a causal structural variant in an exome-negative case and enabled preimplantation genetic diagnosis

genetics more details view paper
  • Downloaded 709 times
  • Download rankings, all-time:
    • Site-wide: 30,188
    • In genetics: 1,524
  • Year to date:
    • Site-wide: 110,165
  • Since beginning of last month:
    • Site-wide: 82,970

Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

cell biology more details view paper
  • Downloaded 648 times
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    • Site-wide: 34,035
    • In cell biology: 1,385
  • Year to date:
    • Site-wide: 62,179
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    • Site-wide: 55,139

Ligation-anchored PCR unveils immune repertoire of TCR-beta from whole blood

genomics more details view paper
  • Downloaded 646 times
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    • Site-wide: 34,207
    • In genomics: 3,030
  • Year to date:
    • Site-wide: 116,574
  • Since beginning of last month:
    • Site-wide: 65,961

Progression, recovery and fatality in patients with SARS-CoV-2 related pneumonia in Wuhan, China: a single-centered, retrospective, observational study

infectious diseases more details view paper
  • Downloaded 620 times
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    • Site-wide: 36,117
    • In infectious diseases: 2,013
  • Year to date:
    • Site-wide: 40,079
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    • Site-wide: 22,334

Phen2Gene: Rapid Phenotype-Driven Gene Prioritization for Rare Diseases

bioinformatics more details view paper
  • Downloaded 620 times
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    • Site-wide: 36,114
    • In bioinformatics: 4,053
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    • Site-wide: 81,187
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A rapid and efficient screening system for neutralizing antibodies and its application for the discovery of potent neutralizing antibodies to SARS-CoV-2 S-RBD

immunology more details view paper
  • Downloaded 603 times
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    • Site-wide: 37,365
    • In immunology: 986
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    • Site-wide: 8,863
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    • Site-wide: 16,421

ADAMTS-family protease MIG-17 regulates synaptic allometry by modifying the extracellular matrix and modulating glia morphology during growth

neuroscience more details view paper
  • Downloaded 540 times
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    • Site-wide: 42,928
    • In neuroscience: 6,346
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    • Site-wide: 115,969
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    • Site-wide: 64,483

Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1

genetics more details view paper
  • Downloaded 444 times
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    • Site-wide: 53,708
    • In genetics: 2,591
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    • Site-wide: 48,728
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    • Site-wide: 79,117

Mechanistic insights on metabolic dysfunction in PTSD: Role of glucocorticoid receptor sensitivity and energy deficit

systems biology more details view paper
  • Downloaded 429 times
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    • Site-wide: 55,680
    • In systems biology: 1,369
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    • Site-wide: 42,284
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    • Site-wide: 72,767

Genome-wide selection footprints and deleterious variations in young Asian allotetraploid rapeseed

genomics more details view paper
  • Downloaded 420 times
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    • Site-wide: 56,884
    • In genomics: 4,301
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    • Site-wide: 112,192
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    • Site-wide: 63,283

DNA demethylation is a driver for chick retina regeneration

developmental biology more details view paper
  • Downloaded 404 times
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    • Site-wide: 59,198
    • In developmental biology: 1,518
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    • Site-wide: 69,987
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    • Site-wide: 107,168

PSC-RED, an Albumin-Free Robust Erythroid Differentiation Method to Produce Enucleated Red Blood Cells from Human Pluripotent Stem Cells

bioengineering more details view paper
  • Downloaded 404 times
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    • Site-wide: 59,139
    • In bioengineering: 1,073
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    • Site-wide: 49,330
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    • Site-wide: 71,384

A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders

systems biology more details view paper
  • Downloaded 399 times
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    • Site-wide: 59,976
    • In systems biology: 1,485
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    • Site-wide: 38,964
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    • Site-wide: 17,336

Longitudinal dynamics of the neutralizing antibody response to SARS-CoV-2 infection

infectious diseases more details view paper
  • Downloaded 397 times
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    • Site-wide: 60,199
    • In infectious diseases: 2,557
  • Year to date:
    • Site-wide: 85,525
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    • Site-wide: 84,972

A novel phyllosphere resident Protomyces species that interacts with the Arabidopsis immune system

microbiology more details view paper
  • Downloaded 392 times
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    • Site-wide: 60,975
    • In microbiology: 4,098
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    • Site-wide: 51,614
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    • Site-wide: 48,361

MicroRNA-transcriptome networks in whole blood and monocytes of women undergoing preterm labor

systems biology more details view paper
  • Downloaded 387 times
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    • Site-wide: 61,700
    • In systems biology: 1,534
  • Year to date:
    • Site-wide: 44,557
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    • Site-wide: 104,521

A key linear epitope for a potent neutralizing antibody to SARS-CoV-2 S-RBD

immunology more details view paper
  • Downloaded 361 times
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    • Site-wide: 65,860
    • In immunology: 1,741
  • Year to date:
    • Site-wide: 9,393
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    • Site-wide: 15,586

Implications of error-prone long-read whole-genome shotgun sequencing on characterizing reference microbiomes

genomics more details view paper
  • Downloaded 345 times
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    • Site-wide: 68,645
    • In genomics: 4,815
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    • Site-wide: 46,046
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    • Site-wide: 85,483

Characterizing the Cancer-Associated Microbiome with Small RNA Sequencing Data

bioinformatics more details view paper
  • Downloaded 341 times
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    • Site-wide: 69,381
    • In bioinformatics: 6,667
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    • Site-wide: 35,615
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Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia

cancer biology more details view paper
  • Downloaded 327 times
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    • Site-wide: 71,776
    • In cancer biology: 2,097
  • Year to date:
    • Site-wide: 4,920
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    • Site-wide: 1,309

Changes of Humoral Immunity Response in SARS-CoV-2 Convalescent Patients over 8 months

infectious diseases more details view paper
  • Downloaded 314 times
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    • Site-wide: 73,996
    • In infectious diseases: 2,832
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    • Site-wide: 45,119
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    • Site-wide: 16,825

Transcriptional Network Analysis on Brains Reveals a Potential Regulatory Role of PPP1R3F in Autism Spectrum Disorders

bioinformatics more details view paper
  • Downloaded 269 times
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    • Site-wide: 82,777
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MNC-RED a Chemically Defined Method to Produce Enucleated Red Blood Cells from Adult Peripheral Blood Mononuclear Cells

bioengineering more details view paper
  • Downloaded 237 times
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    • Site-wide: 89,470
    • In bioengineering: 1,703
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    • Site-wide: 120,224
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    • Site-wide: 67,043

Improved symptoms following bumetanide treatment in children aged 3 to 6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial

pediatrics more details view paper
  • Downloaded 235 times
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    • Site-wide: 89,956
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    • Site-wide: 16,202

LIQA: Long-read Isoform Quantification and Analysis

bioinformatics more details view paper
  • Downloaded 231 times
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    • Site-wide: 90,877
    • In bioinformatics: 8,036
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The CDK inhibitor SIAMESE targets both CDKA;1 and CDKB1 complexes to establish endoreplication in trichomes

plant biology more details view paper
  • Downloaded 229 times
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    • Site-wide: 91,122
    • In plant biology: 2,455
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Temporal regulation of prenatal embryonic development by paternal imprinted loci

developmental biology more details view paper
  • Downloaded 229 times
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    • In developmental biology: 2,491
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Temporal Small RNA Expression Profiling Under Drought Reveals a Potential Regulatory Role of snoRNAs in Drought Responses of Maize

genomics more details view paper
  • Downloaded 228 times
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Independent parental contributions initiate zygote polarization in Arabidopsis thaliana

plant biology more details view paper
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    • In plant biology: 2,529
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1RS.1BL molecular resolution provides novel contributions to wheat improvement

genomics more details view paper
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    • Site-wide: 94,808
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    • Site-wide: 23,048
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Epidemiology, Microbiology and Therapeutic Consequences of Chronic Osteomyelitis in Northern China: A Retrospective Analysis of 255 Patients

microbiology more details view paper
  • Downloaded 208 times
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    • Site-wide: 95,706
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    • Site-wide: 108,056
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    • Site-wide: 106,499

O-GlcNAcylation of SAMHD1 Indicating a Link between Metabolic Reprogramming and Anti-HBV Immunity

microbiology more details view paper
  • Downloaded 202 times
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    • Site-wide: 97,016
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    • Site-wide: 75,977
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Cell type-specific proteogenomic signal diffusion for integrating multi-omics data predicts novel schizophrenia risk genes

systems biology more details view paper
  • Downloaded 186 times
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    • Site-wide: 100,406
    • In systems biology: 2,344
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    • Site-wide: 100,710
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A novel Arabidopsis phyllosphere resident Protomyces sp. and a re-examination of genus Protomyces based on genome sequence data.

microbiology more details view paper
  • Downloaded 173 times
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    • Site-wide: 102,874
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Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products in vitro

microbiology more details view paper
  • Downloaded 168 times
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CancerVar: a web server for improved evidence-based clinical interpretation of cancer somatic mutations and copy number abnormalities

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Gluconeogenic Enzyme PCK1 Deficiency Is Critical for CHK2 O-GlcNAcylation and Hepatocellular Carcinoma Growth upon Glucose Deprivation

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A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment

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GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis

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Biological Correlations and Confounding Variables for Quantification of Retinal Ganglion Cells Based on Optical Coherence Tomography Using Diversity Outbred Mice

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