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Author: Stephen R. Quake

Rankings

  • All-time downloads: 124,261 (rank: 703 )
  • Categories:
    • biochemistry: 261 (rank: 16,967 (tie) )
    • bioengineering: 2,135 (rank: 1,009 (tie) )
    • bioinformatics: 5,269 (rank: 2,122 )
    • biophysics: 511 (rank: 9,262 (tie) )
    • cancer biology: 3,228 (rank: 1,169 (tie) )
    • cell biology: 25,066 (rank: 4 )
    • developmental biology: 2,771 (rank: 714 )
    • genetics: 1,927 (rank: 9,047 (tie) )
    • genomics: 40,068 (rank: 188 )
    • immunology: 14,955 (rank: 494 )
    • microbiology: 7,149 (rank: 1,631 )
    • molecular biology: 427 (rank: 12,939 (tie) )
    • neuroscience: 18,656 (rank: 315 )
    • systems biology: 1,838 (rank: 2,142 (tie) )

Downloads per author, site-wide

Preprints

A molecular cell atlas of the human lung from single cell RNA sequencing

genomics more details view paper
  • Downloaded 18,318 times
  • Download rankings, all-time:
    • Site-wide: 354
    • In genomics: 16
  • Year to date:
    • Site-wide: 547
  • Since beginning of last month:
    • Site-wide: 547

Single-cell transcriptomic characterization of 20 organs and tissues from individual mice creates a Tabula Muris

cell biology more details view paper
  • Downloaded 13,164 times
  • Download rankings, all-time:
    • Site-wide: 504
    • In cell biology: 2
  • Year to date:
    • Site-wide: 14,001
  • Since beginning of last month:
    • Site-wide: 14,001

A Single Cell Transcriptomic Atlas Characterizes Aging Tissues in the Mouse

cell biology more details view paper
  • Downloaded 8,828 times
  • Download rankings, all-time:
    • Site-wide: 881
    • In cell biology: 9
  • Year to date:
    • Site-wide: 3,443
  • Since beginning of last month:
    • Site-wide: 3,443

c-Jun Overexpressing CAR-T Cells are Exhaustion-Resistant and Mediate Enhanced Antitumor Activity

immunology more details view paper
  • Downloaded 3,945 times
  • Download rankings, all-time:
    • Site-wide: 2,587
    • In immunology: 71
  • Year to date:
    • Site-wide: 23,012
  • Since beginning of last month:
    • Site-wide: 23,012

Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ pro-inflammatory macrophages

immunology more details view paper
  • Downloaded 3,455 times
  • Download rankings, all-time:
    • Site-wide: 3,155
    • In immunology: 85
  • Year to date:
    • Site-wide: 5,526
  • Since beginning of last month:
    • Site-wide: 5,526

The murine transcriptome reveals global aging nodes with organ-specific phase and amplitude

genomics more details view paper
  • Downloaded 3,252 times
  • Download rankings, all-time:
    • Site-wide: 3,442
    • In genomics: 395
  • Year to date:
    • Site-wide: 38,989
  • Since beginning of last month:
    • Site-wide: 38,989

Developmental heterogeneity of microglia and brain myeloid cells revealed by deep single-cell RNA sequencing

neuroscience more details view paper
  • Downloaded 3,108 times
  • Download rankings, all-time:
    • Site-wide: 3,674
    • In neuroscience: 303
  • Year to date:
    • Site-wide: 78,952
  • Since beginning of last month:
    • Site-wide: 78,952

Single cell profiling of total RNA using Smart-seq-total

genomics more details view paper
  • Downloaded 2,898 times
  • Download rankings, all-time:
    • Site-wide: 4,020
    • In genomics: 469
  • Year to date:
    • Site-wide: 2,608
  • Since beginning of last month:
    • Site-wide: 2,608

Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-cell RNA Sequencing

genomics more details view paper
  • Downloaded 2,871 times
  • Download rankings, all-time:
    • Site-wide: 4,069
    • In genomics: 472
  • Year to date:
    • Site-wide: 84,444
  • Since beginning of last month:
    • Site-wide: 84,444

Pancreas patch-seq links physiologic dysfunction in diabetes to single-cell transcriptomic phenotypes

genomics more details view paper
  • Downloaded 2,578 times
  • Download rankings, all-time:
    • Site-wide: 4,776
    • In genomics: 555
  • Year to date:
    • Site-wide: 22,472
  • Since beginning of last month:
    • Site-wide: 22,472

Single cell RNAseq provides a molecular and cellular cartography of changes to the human endometrium through the menstrual cycle

genomics more details view paper
  • Downloaded 2,546 times
  • Download rankings, all-time:
    • Site-wide: 4,862
    • In genomics: 567
  • Year to date:
    • Site-wide: 16,203
  • Since beginning of last month:
    • Site-wide: 16,203

Serotonin Neurons in the Dorsal and Medial Raphe Nuclei: from Single-Cell Transcriptomes to Whole-Brain Projections

neuroscience more details view paper
  • Downloaded 2,272 times
  • Download rankings, all-time:
    • Site-wide: 5,787
    • In neuroscience: 561
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: None

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers New Wiring Regulators

neuroscience more details view paper
  • Downloaded 2,202 times
  • Download rankings, all-time:
    • Site-wide: 6,032
    • In neuroscience: 590
  • Year to date:
    • Site-wide: 52,835
  • Since beginning of last month:
    • Site-wide: 52,835

Brain endothelial cells are exquisite sensors of age-related circulatory cues

neuroscience more details view paper
  • Downloaded 2,196 times
  • Download rankings, all-time:
    • Site-wide: 6,053
    • In neuroscience: 592
  • Year to date:
    • Site-wide: 14,017
  • Since beginning of last month:
    • Site-wide: 14,017

Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA

cancer biology more details view paper
  • Downloaded 2,070 times
  • Download rankings, all-time:
    • Site-wide: 6,593
    • In cancer biology: 104
  • Year to date:
    • Site-wide: 32,419
  • Since beginning of last month:
    • Site-wide: 32,419

A mouse tissue atlas of small non-coding RNA

genomics more details view paper
  • Downloaded 1,957 times
  • Download rankings, all-time:
    • Site-wide: 7,146
    • In genomics: 801
  • Year to date:
    • Site-wide: 17,416
  • Since beginning of last month:
    • Site-wide: 17,416

Nonivasive prenatal diagnosis of single-gene disorders using droplet digital PCR

genetics more details view paper
  • Downloaded 1,927 times
  • Download rankings, all-time:
    • Site-wide: 7,311
    • In genetics: 353
  • Year to date:
    • Site-wide: 29,237
  • Since beginning of last month:
    • Site-wide: 29,237

Single-cell analysis identifies EpCAM+/CDH6+/TROP-2- cells as human liver progenitors.

cell biology more details view paper
  • Downloaded 1,917 times
  • Download rankings, all-time:
    • Site-wide: 7,376
    • In cell biology: 173
  • Year to date:
    • Site-wide: 32,446
  • Since beginning of last month:
    • Site-wide: 32,446

Self-assembling Manifolds in Single-cell RNA Sequencing Data

bioinformatics more details view paper
  • Downloaded 1,893 times
  • Download rankings, all-time:
    • Site-wide: 7,496
    • In bioinformatics: 925
  • Year to date:
    • Site-wide: 71,019
  • Since beginning of last month:
    • Site-wide: 71,019

Single cell transcriptome analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns.

genomics more details view paper
  • Downloaded 1,889 times
  • Download rankings, all-time:
    • Site-wide: 7,523
    • In genomics: 835
  • Year to date:
    • Site-wide: 62,799
  • Since beginning of last month:
    • Site-wide: 62,799

Human IgE producing B cells have a unique transcriptional program and generate high affinity, allergen-specific antibodies

immunology more details view paper
  • Downloaded 1,877 times
  • Download rankings, all-time:
    • Site-wide: 7,601
    • In immunology: 205
  • Year to date:
    • Site-wide: 54,638
  • Since beginning of last month:
    • Site-wide: 54,638

Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks

neuroscience more details view paper
  • Downloaded 1,869 times
  • Download rankings, all-time:
    • Site-wide: 7,655
    • In neuroscience: 803
  • Year to date:
    • Site-wide: 5,508
  • Since beginning of last month:
    • Site-wide: 5,508

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set

neuroscience more details view paper
  • Downloaded 1,843 times
  • Download rankings, all-time:
    • Site-wide: 7,824
    • In neuroscience: 822
  • Year to date:
    • Site-wide: 11,999
  • Since beginning of last month:
    • Site-wide: 11,999

Single-cell RNA-seq reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

systems biology more details view paper
  • Downloaded 1,838 times
  • Download rankings, all-time:
    • Site-wide: 7,855
    • In systems biology: 140
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: None

Humans are colonized by many uncharacterized and highly divergent microbes

microbiology more details view paper
  • Downloaded 1,580 times
  • Download rankings, all-time:
    • Site-wide: 9,895
    • In microbiology: 549
  • Year to date:
    • Site-wide: 97,705
  • Since beginning of last month:
    • Site-wide: 97,705

Molecular hallmarks of heterochronic parabiosis at single cell resolution

genomics more details view paper
  • Downloaded 1,492 times
  • Download rankings, all-time:
    • Site-wide: 10,744
    • In genomics: 1,195
  • Year to date:
    • Site-wide: 1,758
  • Since beginning of last month:
    • Site-wide: 1,758

Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples

microbiology more details view paper
  • Downloaded 1,488 times
  • Download rankings, all-time:
    • Site-wide: 10,783
    • In microbiology: 598
  • Year to date:
    • Site-wide: 122,265
  • Since beginning of last month:
    • Site-wide: 122,265

Single-cell transcriptional dynamics of flavivirus infection

microbiology more details view paper
  • Downloaded 1,394 times
  • Download rankings, all-time:
    • Site-wide: 11,902
    • In microbiology: 664
  • Year to date:
    • Site-wide: 70,714
  • Since beginning of last month:
    • Site-wide: 70,714

Discrete and Continuous Cell Identities of the Adult Murine Striatum

neuroscience more details view paper
  • Downloaded 1,361 times
  • Download rankings, all-time:
    • Site-wide: 12,319
    • In neuroscience: 1,440
  • Year to date:
    • Site-wide: 20,583
  • Since beginning of last month:
    • Site-wide: 20,583

Persistent transcriptional programs are associated with remote memory in diverse cells of the medial prefrontal cortex

neuroscience more details view paper
  • Downloaded 1,334 times
  • Download rankings, all-time:
    • Site-wide: 12,715
    • In neuroscience: 1,489
  • Year to date:
    • Site-wide: 27,180
  • Since beginning of last month:
    • Site-wide: 27,180

Transcriptional program of memory B cell activation, broadly binding anti-influenza antibodies, and bystander activation after vaccination revealed by single-cell transcriptomics

immunology more details view paper
  • Downloaded 1,326 times
  • Download rankings, all-time:
    • Site-wide: 12,827
    • In immunology: 348
  • Year to date:
    • Site-wide: 9,288
  • Since beginning of last month:
    • Site-wide: 9,288

Coordinating Receptor Expression and Wiring Specificity in Olfactory Receptor Neurons

neuroscience more details view paper
  • Downloaded 1,318 times
  • Download rankings, all-time:
    • Site-wide: 12,929
    • In neuroscience: 1,513
  • Year to date:
    • Site-wide: 34,354
  • Since beginning of last month:
    • Site-wide: 34,354

Single-Cell RNAseq analysis of infiltrating neoplastic cells at the migrating front of human glioblastoma

cancer biology more details view paper
  • Downloaded 1,158 times
  • Download rankings, all-time:
    • Site-wide: 15,725
    • In cancer biology: 349
  • Year to date:
    • Site-wide: 48,483
  • Since beginning of last month:
    • Site-wide: 48,483

Signatures of Selection in the Human Antibody Repertoire: Selective Sweeps, Competing Subclones, and Neutral Drift

immunology more details view paper
  • Downloaded 1,074 times
  • Download rankings, all-time:
    • Site-wide: 17,632
    • In immunology: 492
  • Year to date:
    • Site-wide: 92,366
  • Since beginning of last month:
    • Site-wide: 92,366

5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

genomics more details view paper
  • Downloaded 1,068 times
  • Download rankings, all-time:
    • Site-wide: 17,760
    • In genomics: 1,843
  • Year to date:
    • Site-wide: 78,575
  • Since beginning of last month:
    • Site-wide: 78,575

PhaMers identifies novel bacteriophage sequences from thermophilic hot springs

bioinformatics more details view paper
  • Downloaded 1,043 times
  • Download rankings, all-time:
    • Site-wide: 18,418
    • In bioinformatics: 2,229
  • Year to date:
    • Site-wide: 61,826
  • Since beginning of last month:
    • Site-wide: 61,826

Molecular and genetic regulation of pig pancreatic islet cell development

developmental biology more details view paper
  • Downloaded 1,040 times
  • Download rankings, all-time:
    • Site-wide: 18,512
    • In developmental biology: 320
  • Year to date:
    • Site-wide: 21,751
  • Since beginning of last month:
    • Site-wide: 21,751

Mapping single-cell atlases throughout Metazoa unravels cell type evolution

bioinformatics more details view paper
  • Downloaded 988 times
  • Download rankings, all-time:
    • Site-wide: 19,915
    • In bioinformatics: 2,403
  • Year to date:
    • Site-wide: 2,630
  • Since beginning of last month:
    • Site-wide: 2,630

Hydrogenotrophic methanogenesis in archaeal phylum Verstraetearchaeota reveals the shared ancestry of all methanogens

microbiology more details view paper
  • Downloaded 949 times
  • Download rankings, all-time:
    • Site-wide: 21,099
    • In microbiology: 1,196
  • Year to date:
    • Site-wide: 119,430
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    • Site-wide: 119,430

Dynamics Of The Human Antibody Repertoire Following B-cell Depletion In Systemic Sclerosis

immunology more details view paper
  • Downloaded 940 times
  • Download rankings, all-time:
    • Site-wide: 21,383
    • In immunology: 595
  • Year to date:
    • Site-wide: 54,767
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    • Site-wide: 54,767

Evolutionary Origin of the Mammalian Hematopoietic System Found in a Colonial Chordate

immunology more details view paper
  • Downloaded 930 times
  • Download rankings, all-time:
    • Site-wide: 21,724
    • In immunology: 607
  • Year to date:
    • Site-wide: 46,083
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    • Site-wide: 46,083

Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infection

immunology more details view paper
  • Downloaded 914 times
  • Download rankings, all-time:
    • Site-wide: 22,285
    • In immunology: 632
  • Year to date:
    • Site-wide: 95,626
  • Since beginning of last month:
    • Site-wide: 95,626

A single-parasite transcriptional atlas of Toxoplasma gondii reveals novel control of antigen expression

bioengineering more details view paper
  • Downloaded 899 times
  • Download rankings, all-time:
    • Site-wide: 22,831
    • In bioengineering: 382
  • Year to date:
    • Site-wide: 73,037
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    • Site-wide: 73,037

Northstar enables automatic classification of known and novel cell types from tumor samples

bioinformatics more details view paper
  • Downloaded 842 times
  • Download rankings, all-time:
    • Site-wide: 25,041
    • In bioinformatics: 2,983
  • Year to date:
    • Site-wide: 44,657
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    • Site-wide: 44,657

A Noninvasive Molecular Clock for Fetal Development Predicts Gestational Age and Preterm Delivery

bioengineering more details view paper
  • Downloaded 798 times
  • Download rankings, all-time:
    • Site-wide: 26,972
    • In bioengineering: 461
  • Year to date:
    • Site-wide: 100,591
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    • Site-wide: 100,591

Nucleic Acid Cleavage with a Hyperthermophilic Cas9 from an Unculturable Ignavibacterium

genomics more details view paper
  • Downloaded 699 times
  • Download rankings, all-time:
    • Site-wide: 32,433
    • In genomics: 2,901
  • Year to date:
    • Site-wide: 53,764
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    • Site-wide: 53,764

Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung revealed at single cell resolution

developmental biology more details view paper
  • Downloaded 698 times
  • Download rankings, all-time:
    • Site-wide: 32,535
    • In developmental biology: 691
  • Year to date:
    • Site-wide: 36,182
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    • Site-wide: 36,182

Latrophilin-2 repels Teneurin-3+ hippocampal axons during target selection

neuroscience more details view paper
  • Downloaded 622 times
  • Download rankings, all-time:
    • Site-wide: 37,933
    • In neuroscience: 5,397
  • Year to date:
    • Site-wide: 22,311
  • Since beginning of last month:
    • Site-wide: 22,311

Single-cell transcriptional atlas of the Chinese horseshoe bat (Rhinolophus sinicus) provides insight into the cellular mechanisms which enable bats to be viral reservoirs

cell biology more details view paper
  • Downloaded 604 times
  • Download rankings, all-time:
    • Site-wide: 39,261
    • In cell biology: 1,614
  • Year to date:
    • Site-wide: 14,151
  • Since beginning of last month:
    • Site-wide: 14,151

Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons

neuroscience more details view paper
  • Downloaded 531 times
  • Download rankings, all-time:
    • Site-wide: 46,129
    • In neuroscience: 6,754
  • Year to date:
    • Site-wide: 21,442
  • Since beginning of last month:
    • Site-wide: 21,442

Functional characterization and lineage analysis of broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics

microbiology more details view paper
  • Downloaded 521 times
  • Download rankings, all-time:
    • Site-wide: 47,194
    • In microbiology: 2,958
  • Year to date:
    • Site-wide: 65,317
  • Since beginning of last month:
    • Site-wide: 65,317

Molecular and Morphological Signatures of Chordate Development: Two Distinct Pathways, One Tunicate

developmental biology more details view paper
  • Downloaded 512 times
  • Download rankings, all-time:
    • Site-wide: 48,124
    • In developmental biology: 1,154
  • Year to date:
    • Site-wide: 65,560
  • Since beginning of last month:
    • Site-wide: 65,560

Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo

biophysics more details view paper
  • Downloaded 511 times
  • Download rankings, all-time:
    • Site-wide: 48,168
    • In biophysics: 1,630
  • Year to date:
    • Site-wide: 72,101
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    • Site-wide: 72,101

Modeling Spatial Correlation of Transcripts With Application to Developing Pancreas

bioinformatics more details view paper
  • Downloaded 503 times
  • Download rankings, all-time:
    • Site-wide: 49,102
    • In bioinformatics: 5,130
  • Year to date:
    • Site-wide: 113,083
  • Since beginning of last month:
    • Site-wide: 113,083

Viral Taxonomy Derived From Evolutionary Genome Relationships

genomics more details view paper
  • Downloaded 500 times
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    • Site-wide: 49,434
    • In genomics: 3,917
  • Year to date:
    • Site-wide: 93,267
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    • Site-wide: 93,267

Matrix-corrected mass spectrometry enables sensitive detection of food allergens and reveals widespread soy contamination of processed foods

immunology more details view paper
  • Downloaded 494 times
  • Download rankings, all-time:
    • Site-wide: 50,148
    • In immunology: 1,369
  • Year to date:
    • Site-wide: 92,154
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    • Site-wide: 92,154

The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection

microbiology more details view paper
  • Downloaded 481 times
  • Download rankings, all-time:
    • Site-wide: 51,720
    • In microbiology: 3,298
  • Year to date:
    • Site-wide: 34,869
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    • Site-wide: 34,869

Single-cell analysis of Schistosoma mansoni reveals a conserved genetic program controlling germline stem cell fate

developmental biology more details view paper
  • Downloaded 438 times
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    • Site-wide: 57,290
    • In developmental biology: 1,435
  • Year to date:
    • Site-wide: 36,597
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    • Site-wide: 36,597

An inexpensive semi-automated sample processing pipeline for cell-free RNA

bioengineering more details view paper
  • Downloaded 438 times
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    • Site-wide: 57,306
    • In bioengineering: 1,054
  • Year to date:
    • Site-wide: 16,470
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    • Site-wide: 16,470

Non-invasive characterization of human bone marrow by cell free messenger-RNA reveals response to growth factor stimulation and hematopoietic reconstitution after transplantation

molecular biology more details view paper
  • Downloaded 427 times
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    • Site-wide: 58,820
    • In molecular biology: 1,690
  • Year to date:
    • Site-wide: 93,601
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    • Site-wide: 93,601

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

microbiology more details view paper
  • Downloaded 372 times
  • Download rankings, all-time:
    • Site-wide: 67,236
    • In microbiology: 4,566
  • Year to date:
    • Site-wide: 88,085
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    • Site-wide: 88,085

Cell-free DNA Reveals Potential Zoonotic Reservoirs in Non-Human Primates

microbiology more details view paper
  • Downloaded 364 times
  • Download rankings, all-time:
    • Site-wide: 68,584
    • In microbiology: 4,670
  • Year to date:
    • Site-wide: 86,129
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    • Site-wide: 86,129

NFIA regulates granule recruitment and exocytosis in the adult pancreas

cell biology more details view paper
  • Downloaded 351 times
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    • Site-wide: 70,828
    • In cell biology: 3,243
  • Year to date:
    • Site-wide: 49,820
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    • Site-wide: 49,820

Kinetics and Fidelity of Psychrophilic DNA Polymerases

biochemistry more details view paper
  • Downloaded 261 times
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    • Site-wide: 88,310
    • In biochemistry: 2,555
  • Year to date:
    • Site-wide: 40,987
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    • Site-wide: 40,987

Single-cell RNA Expression of SARS-CoV-2 Cell Entry Factors in Human Endometrium during Preconception

cell biology more details view paper
  • Downloaded 202 times
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    • Site-wide: 100,981
    • In cell biology: 4,694
  • Year to date:
    • Site-wide: 64,608
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    • Site-wide: 64,608

Global Age-Specific Patterns of Cyclic Gene Expression Revealed by Tunicate Transcriptome Atlas

developmental biology more details view paper
  • Downloaded 83 times
  • Download rankings, all-time:
    • Site-wide: 123,388
    • In developmental biology: 3,275
  • Year to date:
    • Site-wide: 55,842
  • Since beginning of last month:
    • Site-wide: 55,842

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