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Author: Chen Chen

Rankings

  • All-time downloads: 48,484 (rank: 4,445 )
  • Categories:
    • biochemistry: 1,489 (rank: 4,359 (tie) )
    • bioinformatics: 5,970 (rank: 2,449 (tie) )
    • biophysics: 543 (rank: 13,417 (tie) )
    • cancer biology: 5,444 (rank: 778 (tie) )
    • cardiovascular medicine: 629 (rank: 1,407 (tie) )
    • cell biology: 4,714 (rank: 1,160 )
    • developmental biology: 647 (rank: 9,911 (tie) )
    • epidemiology: 2,879 (rank: 5,657 )
    • evolutionary biology: 1,011 (rank: 8,726 (tie) )
    • genetics: 599 (rank: 26,950 (tie) )
    • geriatric medicine: 431 (rank: 490 (tie) )
    • immunology: 1,151 (rank: 12,912 (tie) )
    • infectious diseases: 7,438 (rank: 8,180 )
    • microbiology: 4,527 (rank: 4,131 )
    • molecular biology: 4,086 (rank: 1,148 )
    • neurology: 148 (rank: 9,086 (tie) )
    • neuroscience: 1,975 (rank: 15,276 (tie) )
    • plant biology: 3,295 (rank: 822 )
    • public and global health: 1,508 (rank: 3,665 )

Downloads per author, site-wide

Preprints

Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and the potential for differential clinical activity

cancer biology more details view paper
  • Downloaded 4,621 times
  • Download rankings, all-time:
    • Site-wide: 3,151
    • In cancer biology: 38
  • Year to date:
    • Site-wide: 6,779
  • Since beginning of last month:
    • Site-wide: 28,373

MVP: predicting pathogenicity of missense variants by deep learning

bioinformatics more details view paper
  • Downloaded 3,961 times
  • Download rankings, all-time:
    • Site-wide: 3,887
    • In bioinformatics: 337
  • Year to date:
    • Site-wide: 46,380
  • Since beginning of last month:
    • Site-wide: 31,605

Clinical characteristics of 101 non-surviving hospitalized patients with COVID-19: A single center, retrospective study

infectious diseases more details view paper
  • Downloaded 3,954 times
  • Download rankings, all-time:
    • Site-wide: 3,895
    • In infectious diseases: 856
  • Year to date:
    • Site-wide: 12,897
  • Since beginning of last month:
    • Site-wide: 25,963

Estimating the case fatality ratio of the COVID-19 epidemic in China

infectious diseases more details view paper
  • Downloaded 3,484 times
  • Download rankings, all-time:
    • Site-wide: 4,670
    • In infectious diseases: 968
  • Year to date:
    • Site-wide: 18,967
  • Since beginning of last month:
    • Site-wide: 33,208

MINERVA: A facile strategy for SARS-CoV-2 whole genome deep sequencing of clinical samples

molecular biology more details view paper
  • Downloaded 2,022 times
  • Download rankings, all-time:
    • Site-wide: 10,280
    • In molecular biology: 258
  • Year to date:
    • Site-wide: 49,799
  • Since beginning of last month:
    • Site-wide: 50,193

Global Prevalence of Post-Acute Sequelae of COVID-19 (PASC) or Long COVID: A Meta-Analysis and Systematic Review

epidemiology more details view paper
  • Downloaded 1,764 times
  • Download rankings, all-time:
    • Site-wide: 12,570
    • In epidemiology: 952
  • Year to date:
    • Site-wide: 1,009
  • Since beginning of last month:
    • Site-wide: 1,389

High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification

biochemistry more details view paper
  • Downloaded 1,489 times
  • Download rankings, all-time:
    • Site-wide: 16,286
    • In biochemistry: 334
  • Year to date:
    • Site-wide: 24,918
  • Since beginning of last month:
    • Site-wide: 41,132

Life history recorded in the vagino-cervical microbiome

microbiology more details view paper
  • Downloaded 1,302 times
  • Download rankings, all-time:
    • Site-wide: 19,926
    • In microbiology: 1,156
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 81,837

Extension of the in vivo haploid induction system from maize to wheat

plant biology more details view paper
  • Downloaded 1,123 times
  • Download rankings, all-time:
    • Site-wide: 24,981
    • In plant biology: 374
  • Year to date:
    • Site-wide: 135,544
  • Since beginning of last month:
    • Site-wide: 20,886

Cryo-ET reveals nucleosome reorganization in condensed mitotic chromosomes in vivo

cell biology more details view paper
  • Downloaded 1,051 times
  • Download rankings, all-time:
    • Site-wide: 27,632
    • In cell biology: 1,003
  • Year to date:
    • Site-wide: 136,717
  • Since beginning of last month:
    • Site-wide: 155,458

A valid protective immune response elicited in rhesus macaques by an inactivated vaccine is capable of defending against SARS-CoV-2 infection

immunology more details view paper
  • Downloaded 937 times
  • Download rankings, all-time:
    • Site-wide: 32,716
    • In immunology: 1,094
  • Year to date:
    • Site-wide: 38,314
  • Since beginning of last month:
    • Site-wide: 44,744

A VTA GABAergic neural circuit mediates visually evoked innate defensive responses

neuroscience more details view paper
  • Downloaded 933 times
  • Download rankings, all-time:
    • Site-wide: 32,932
    • In neuroscience: 4,255
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 148,286

An Mtb-Human Protein-Protein Interaction Map Reveals that Bacterial LpqN Antagonizes CBL, a Host Ubiquitin Ligase that Regulates the Balance Between Anti-Viral and Anti-Bacterial Responses

microbiology more details view paper
  • Downloaded 918 times
  • Download rankings, all-time:
    • Site-wide: 33,719
    • In microbiology: 1,981
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 159,905

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo

cell biology more details view paper
  • Downloaded 852 times
  • Download rankings, all-time:
    • Site-wide: 37,545
    • In cell biology: 1,443
  • Year to date:
    • Site-wide: 136,304
  • Since beginning of last month:
    • Site-wide: 102,185

Abusers indoors and coronavirus outside: an examination of public discourse about COVID-19 and family violence on Twitter using machine learning

public and global health more details view paper
  • Downloaded 838 times
  • Download rankings, all-time:
    • Site-wide: 38,497
    • In public and global health: 705
  • Year to date:
    • Site-wide: 68,427
  • Since beginning of last month:
    • Site-wide: 34,029

Accelerated Protein Biomarker Discovery from FFPE tissue samples using Single-shot, Short Gradient Microflow SWATH MS

cancer biology more details view paper
  • Downloaded 823 times
  • Download rankings, all-time:
    • Site-wide: 39,541
    • In cancer biology: 1,065
  • Year to date:
    • Site-wide: 75,083
  • Since beginning of last month:
    • Site-wide: 33,439

A collection of yeast cellular electron cryotomography data

cell biology more details view paper
  • Downloaded 799 times
  • Download rankings, all-time:
    • Site-wide: 41,234
    • In cell biology: 1,622
  • Year to date:
    • Site-wide: 134,766
  • Since beginning of last month:
    • Site-wide: 101,508

Combination of deep neural network with attention mechanism enhances the explainability of protein contact prediction

bioinformatics more details view paper
  • Downloaded 781 times
  • Download rankings, all-time:
    • Site-wide: 42,634
    • In bioinformatics: 4,442
  • Year to date:
    • Site-wide: 116,492
  • Since beginning of last month:
    • Site-wide: 90,459

Characterization of glutamatergic VTA neural population responses to aversive and rewarding conditioning in freely-moving mice

neuroscience more details view paper
  • Downloaded 725 times
  • Download rankings, all-time:
    • Site-wide: 47,345
    • In neuroscience: 6,502
  • Year to date:
    • Site-wide: 44,723
  • Since beginning of last month:
    • Site-wide: 69,836

METTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs

molecular biology more details view paper
  • Downloaded 706 times
  • Download rankings, all-time:
    • Site-wide: 49,104
    • In molecular biology: 1,377
  • Year to date:
    • Site-wide: 27,901
  • Since beginning of last month:
    • Site-wide: 14,575

Natural Chromatin Is Heterogeneous And Self Associates In Vitro

cell biology more details view paper
  • Downloaded 687 times
  • Download rankings, all-time:
    • Site-wide: 51,061
    • In cell biology: 2,148
  • Year to date:
    • Site-wide: 136,462
  • Since beginning of last month:
    • Site-wide: 143,277

Pregnancy reprograms the enhancer landscape of mammary epithelial cells and alters the response to cMYC-driven oncogenesis

molecular biology more details view paper
  • Downloaded 676 times
  • Download rankings, all-time:
    • Site-wide: 52,148
    • In molecular biology: 1,483
  • Year to date:
    • Site-wide: 137,751
  • Since beginning of last month:
    • Site-wide: 122,895

The characteristics and death risk factors of 132 COVID-19 pneumonia patients with comorbidities: a retrospective single center analysis in Wuhan, China

public and global health more details view paper
  • Downloaded 670 times
  • Download rankings, all-time:
    • Site-wide: 52,833
    • In public and global health: 876
  • Year to date:
    • Site-wide: 67,855
  • Since beginning of last month:
    • Site-wide: 57,224

A group of nuclear factor Y transcription factors are likely sub-functionalized in the endosperm development of monocot

plant biology more details view paper
  • Downloaded 665 times
  • Download rankings, all-time:
    • Site-wide: 53,369
    • In plant biology: 1,180
  • Year to date:
    • Site-wide: 76,796
  • Since beginning of last month:
    • Site-wide: 101,991

Inflammation Level Severity and Death in Patients With COVID-19: A Rapid Systematic Review and Meta-Analysis

cardiovascular medicine more details view paper
  • Downloaded 629 times
  • Download rankings, all-time:
    • Site-wide: 57,480
    • In cardiovascular medicine: 105
  • Year to date:
    • Site-wide: 90,718
  • Since beginning of last month:
    • Site-wide: 84,088

The female urinary microbiota in relation to the reproductive tract microbiota

microbiology more details view paper
  • Downloaded 619 times
  • Download rankings, all-time:
    • Site-wide: 58,629
    • In microbiology: 3,624
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 99,770

Contrasting determinants of mutation rates in germline and soma

evolutionary biology more details view paper
  • Downloaded 604 times
  • Download rankings, all-time:
    • Site-wide: 60,564
    • In evolutionary biology: 2,922
  • Year to date:
    • Site-wide: 103,435
  • Since beginning of last month:
    • Site-wide: 117,304

Genomic selection to optimize doubled haploid-based hybrid breeding in maize

genetics more details view paper
  • Downloaded 599 times
  • Download rankings, all-time:
    • Site-wide: 61,290
    • In genetics: 2,563
  • Year to date:
    • Site-wide: 25,571
  • Since beginning of last month:
    • Site-wide: 109,766

A multi-scale model of the yeast chromosome-segregation system

cell biology more details view paper
  • Downloaded 555 times
  • Download rankings, all-time:
    • Site-wide: 67,266
    • In cell biology: 2,963
  • Year to date:
    • Site-wide: 136,974
  • Since beginning of last month:
    • Site-wide: 143,080

A genotype independent DMP-HI system in dicot crops

plant biology more details view paper
  • Downloaded 553 times
  • Download rankings, all-time:
    • Site-wide: 67,544
    • In plant biology: 1,637
  • Year to date:
    • Site-wide: 12,346
  • Since beginning of last month:
    • Site-wide: 9,171

Tuning movement for sensing in an uncertain world

bioinformatics more details view paper
  • Downloaded 545 times
  • Download rankings, all-time:
    • Site-wide: 68,787
    • In bioinformatics: 6,507
  • Year to date:
    • Site-wide: 74,228
  • Since beginning of last month:
    • Site-wide: 87,643

Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike protein and the human ACE2 receptor

biophysics more details view paper
  • Downloaded 543 times
  • Download rankings, all-time:
    • Site-wide: 68,979
    • In biophysics: 2,427
  • Year to date:
    • Site-wide: 55,765
  • Since beginning of last month:
    • Site-wide: 25,353

HiAlc Klebsiella pneumonia, one of potential chief culprits of non-alcoholic fatty liver disease: through generation of endogenous ethanol

microbiology more details view paper
  • Downloaded 530 times
  • Download rankings, all-time:
    • Site-wide: 71,065
    • In microbiology: 4,553
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 147,127

Functional divergence of two duplicated Fertilization Independent Endosperm genes in rice with respect to seed development

plant biology more details view paper
  • Downloaded 481 times
  • Download rankings, all-time:
    • Site-wide: 79,328
    • In plant biology: 2,017
  • Year to date:
    • Site-wide: 142,725
  • Since beginning of last month:
    • Site-wide: 81,056

Characterization Of Imprinted Genes In Rice Reveals Post-Fertilization Regulation And Conservation At Some Loci Of Imprinting In Plant Species

plant biology more details view paper
  • Downloaded 473 times
  • Download rankings, all-time:
    • Site-wide: 80,805
    • In plant biology: 2,052
  • Year to date:
    • Site-wide: 104,079
  • Since beginning of last month:
    • Site-wide: 102,005

Genetic effect of type 2 Diabetes to the progression of Neurological Diseases

bioinformatics more details view paper
  • Downloaded 455 times
  • Download rankings, all-time:
    • Site-wide: 84,260
    • In bioinformatics: 7,567
  • Year to date:
    • Site-wide: 80,671
  • Since beginning of last month:
    • Site-wide: 41,078

A cross-sectional analysis of demographic and behavioral risk factors of SARS-CoV-2 antibody positivity among a sample of U.S. college students

epidemiology more details view paper
  • Downloaded 433 times
  • Download rankings, all-time:
    • Site-wide: 88,834
    • In epidemiology: 3,870
  • Year to date:
    • Site-wide: 91,022
  • Since beginning of last month:
    • Site-wide: 142,275

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation.

developmental biology more details view paper
  • Downloaded 408 times
  • Download rankings, all-time:
    • Site-wide: 94,035
    • In developmental biology: 2,507
  • Year to date:
    • Site-wide: 119,049
  • Since beginning of last month:
    • Site-wide: 65,817

One viral sequence for each host? - The neglected within-host diversity as the main stage of SARS-CoV-2 evolution

evolutionary biology more details view paper
  • Downloaded 407 times
  • Download rankings, all-time:
    • Site-wide: 94,448
    • In evolutionary biology: 4,671
  • Year to date:
    • Site-wide: 70,074
  • Since beginning of last month:
    • Site-wide: 39,243

Systems-wide Analysis Revealed Shared and Unique Responses to Moderate and Acute High Temperatures in the Green Alga Chlamydomonas reinhardtii

cell biology more details view paper
  • Downloaded 398 times
  • Download rankings, all-time:
    • Site-wide: 96,435
    • In cell biology: 4,431
  • Year to date:
    • Site-wide: 5,784
  • Since beginning of last month:
    • Site-wide: 32,462

DNA methylation is indispensable for leukemia inhibitory factor dependent embryonic stem cells reprogramming

cell biology more details view paper
  • Downloaded 372 times
  • Download rankings, all-time:
    • Site-wide: 102,322
    • In cell biology: 4,726
  • Year to date:
    • Site-wide: 127,968
  • Since beginning of last month:
    • Site-wide: 137,774

RNA Polymerase II Independent Recruitment of SPT6 at Transcription Start Sites in Arabidopsis

molecular biology more details view paper
  • Downloaded 359 times
  • Download rankings, all-time:
    • Site-wide: 105,515
    • In molecular biology: 3,126
  • Year to date:
    • Site-wide: 148,290
  • Since beginning of last month:
    • Site-wide: 162,748

Aging metrics incorporating cognitive and physical function capture mortality risk: results from three prospective cohort studies

geriatric medicine more details view paper
  • Downloaded 347 times
  • Download rankings, all-time:
    • Site-wide: 108,690
    • In geriatric medicine: 86
  • Year to date:
    • Site-wide: 42,332
  • Since beginning of last month:
    • Site-wide: 53,270

Antimicrobial Efficacy and Safety of a Novel Gas Plasma-Activated Catheter Lock Solution

microbiology more details view paper
  • Downloaded 338 times
  • Download rankings, all-time:
    • Site-wide: 110,848
    • In microbiology: 7,747
  • Year to date:
    • Site-wide: 78,823
  • Since beginning of last month:
    • Site-wide: 125,726

RNF219 interacts with CCR4-NOT in regulating stem cell differentiation

molecular biology more details view paper
  • Downloaded 323 times
  • Download rankings, all-time:
    • Site-wide: 114,877
    • In molecular biology: 3,397
  • Year to date:
    • Site-wide: 123,440
  • Since beginning of last month:
    • Site-wide: 73,610

Identification of a new orthonairovirus associated with human febrile illness in China

microbiology more details view paper
  • Downloaded 318 times
  • Download rankings, all-time:
    • Site-wide: 116,201
    • In microbiology: 8,181
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 128,050

Glutamatergic and GABAergic neuronal populations in the dorsolateral Periacqueductual Gray have different functional roles in fear conditioning

neuroscience more details view paper
  • Downloaded 317 times
  • Download rankings, all-time:
    • Site-wide: 116,425
    • In neuroscience: 17,381
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 131,758

Personalized vagino-cervical microbiome dynamics after oral probiotics

microbiology more details view paper
  • Downloaded 272 times
  • Download rankings, all-time:
    • Site-wide: 128,673
    • In microbiology: 9,245
  • Year to date:
    • Site-wide: 124,143
  • Since beginning of last month:
    • Site-wide: 133,444

Strong reduction of distal colorectal cancer incidence and mortality but no reduction of proximal colon cancer after screening colonoscopy: prospective cohort study

epidemiology more details view paper
  • Downloaded 262 times
  • Download rankings, all-time:
    • Site-wide: 131,346
    • In epidemiology: 5,544
  • Year to date:
    • Site-wide: 19,904
  • Since beginning of last month:
    • Site-wide: 85,787

Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

developmental biology more details view paper
  • Downloaded 239 times
  • Download rankings, all-time:
    • Site-wide: 137,414
    • In developmental biology: 3,710
  • Year to date:
    • Site-wide: 24,186
  • Since beginning of last month:
    • Site-wide: 24,976

Dynamic Changes of G-CSF etc. Nine Cytokines in Mouse Bloodstream Infection Models of Staphylococcus aureus and Klebsiella pneumoniae and their Clinical Performances

microbiology more details view paper
  • Downloaded 230 times
  • Download rankings, all-time:
    • Site-wide: 139,756
    • In microbiology: 10,223
  • Year to date:
    • Site-wide: 137,538
  • Since beginning of last month:
    • Site-wide: 151,922

Generating Ensembles of Gene Regulatory Networks to Assess Robustness of Disease Modules

bioinformatics more details view paper
  • Downloaded 228 times
  • Download rankings, all-time:
    • Site-wide: 140,256
    • In bioinformatics: 10,993
  • Year to date:
    • Site-wide: 115,110
  • Since beginning of last month:
    • Site-wide: 89,685

High-risk alcohol consumption may increase the risk of SARS-CoV-2 seroconversion: a prospective seroepidemiologic cohort study among American college students

epidemiology more details view paper
  • Downloaded 220 times
  • Download rankings, all-time:
    • Site-wide: 142,404
    • In epidemiology: 5,969
  • Year to date:
    • Site-wide: 32,768
  • Since beginning of last month:
    • Site-wide: 78,765

Pre-diabetes increases tuberculosis disease severity, while high body fat without impaired glucose tolerance is protective

immunology more details view paper
  • Downloaded 214 times
  • Download rankings, all-time:
    • Site-wide: 143,959
    • In immunology: 4,386
  • Year to date:
    • Site-wide: 53,929
  • Since beginning of last month:
    • Site-wide: 116,159

Virtual Exam for Parkinson's Disease Enables Frequent and Reliable Measurements of Motor Function

neurology more details view paper
  • Downloaded 148 times
  • Download rankings, all-time:
    • Site-wide: 158,807
    • In neurology: 941
  • Year to date:
    • Site-wide: 1,654
  • Since beginning of last month:
    • Site-wide: 11,140

High blood uric acid is associated with reduced risks of mild cognitive impairment among older adults in China: a 9-year prospective cohort study

epidemiology more details view paper
  • Downloaded 126 times
  • Download rankings, all-time:
    • Site-wide: 162,829
    • In epidemiology: 6,741
  • Year to date:
    • Site-wide: 95,595
  • Since beginning of last month:
    • Site-wide: 42,079

Predictive utility of mortality by aging measures at different hierarchical levels and the response to modifiable lifestyle factors:Implications for geroprotective programs

geriatric medicine more details view paper
  • Downloaded 84 times
  • Download rankings, all-time:
    • Site-wide: 168,474
    • In geriatric medicine: 119
  • Year to date:
    • Site-wide: 24,678
  • Since beginning of last month:
    • Site-wide: 11,058

Does healthy lifestyle attenuate the detrimental effects of urinary polycyclic aromatic hydrocarbons on phenotypic aging? An analysis from NHANES 2001-2010

epidemiology more details view paper
  • Downloaded 74 times
  • Download rankings, all-time:
    • Site-wide: 169,399
    • In epidemiology: 6,942
  • Year to date:
    • Site-wide: 7,066
  • Since beginning of last month:
    • Site-wide: 12,532

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