Author: Heather C. Whalley

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Preprints

Sex Differences In The Adult Human Brain: Evidence From 5,216 UK Biobank Participants

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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  • In genetics: 85
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Greater male than female variability in regional brain structure across the lifespan

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Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data

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  • In neuroscience: 2,334
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Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

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Epigenetic prediction of complex traits and death

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  • In genomics: 2,083
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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

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  • In genetics: 1,250
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Associations between vascular risk factors and brain MRI indices in UK Biobank

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  • In neuroscience: 5,043
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10Kin1day: A bottom-up neuroimaging initiative

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  • In neuroscience: 6,222
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A meta-analysis of genome-wide association studies of epigenetic age acceleration

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Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.

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DNA methylation age acceleration and risk factors for Alzheimer's disease

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  • In genomics: 3,647
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Accelerated Epigenetic Ageing in Major Depressive Disorder

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  • In genomics: 3,737
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Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

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  • In neuroscience: 8,469
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Epigenetic prediction of major depressive disorder

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  • In psychiatry and clinical psychology: 204
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Cognitive functioning and lifetime Major Depressive Disorder in UK Biobank

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Psychotic-like experiences, polygenic risk scores for schizophrenia and structural properties of the salience, default mode and central-executive networks in healthy participants from UK Biobank

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  • In neuroscience: 10,586
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Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

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An epigenetic proxy of chronic inflammation outperforms serum levels as a biomarker of brain ageing

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  • In neurology: 192
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Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

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  • Site-wide: 94,415
  • In bioinformatics: 8,238
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Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

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Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

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Associations between alcohol use and accelerated biological ageing

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  • Site-wide: 110,107
  • In psychiatry and clinical psychology: 453
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Associations Between Major Psychiatric Disorder Polygenic Risk Scores and Blood-Based Markers in UK Biobank

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The Influence of Phenotyping Method on Neuroimaging Associations with Depression in UK Biobank

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  • Site-wide: 120,458
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Epigenome-wide association study of self-reported antidepressant use in Generation Scotland implicates the innate immune system

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  • In psychiatry and clinical psychology: 591
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