Author: Yu Zhang

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Preprints

The respiratory sound features of COVID-19 patients fill gaps between clinical data and screening methods

• Downloaded 35,482 times
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  • Site-wide: 236
  • In infectious diseases: 92
• Year to date:
  • Site-wide: 272
• Since beginning of last month:
  • Site-wide: 462

Clinical observations of low molecular weight heparin in relieving inflammation in COVID-19 patients: A retrospective cohort study

• Downloaded 10,680 times
• Download rankings, all-time:
  • Site-wide: 1,005
  • In pharmacology and therapeutics: 3
• Year to date:
  • Site-wide: 6,593
• Since beginning of last month:
  • Site-wide: 14,350

Transmission of corona virus disease 2019 during the incubation period may lead to a quarantine loophole

• Downloaded 5,529 times
• Download rankings, all-time:
  • Site-wide: 2,320
  • In epidemiology: 268
• Year to date:
  • Site-wide: 17,873
• Since beginning of last month:
  • Site-wide: 24,101

Survival analysis of hospital length of stay of novel coronavirus (COVID-19) pneumonia patients in Sichuan, China

• Downloaded 3,014 times
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  • Site-wide: 5,450
  • In health policy: 27
• Year to date:
  • Site-wide: 6,500
• Since beginning of last month:
  • Site-wide: 7,192

Antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase: pseudouridimycin

• Downloaded 2,841 times
• Download rankings, all-time:
  • Site-wide: 5,925
  • In molecular biology: 133
• Year to date:
  • Site-wide: 86,741
• Since beginning of last month:
  • Site-wide: 87,379

Re-Evaluating One-step Generation of Mice Carrying Conditional Alleles by CRISPR-Cas9-Mediated Genome Editing Technology

• Downloaded 2,811 times
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  • Site-wide: 6,028
  • In genetics: 240
• Year to date:
  • Site-wide: 70,897
• Since beginning of last month:
  • Site-wide: 117,081

Genomic Architecture of Cells in Tissues (GeACT): Study of Human Mid-gestation Fetus

• Downloaded 2,536 times
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  • Site-wide: 7,019
  • In genomics: 720
• Year to date:
  • Site-wide: 24,174
• Since beginning of last month:
  • Site-wide: 16,087

Cross-type Biomedical Named Entity Recognition with Deep Multi-Task Learning

• Downloaded 2,058 times
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  • Site-wide: 9,516
  • In bioinformatics: 1,061
• Year to date:
  • Site-wide: 27,233
• Since beginning of last month:
  • Site-wide: 25,519

The changing mouse embryo transcriptome at whole tissue and single-cell resolution

• Downloaded 2,035 times
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  • Site-wide: 9,682
  • In developmental biology: 122
• Year to date:
  • Site-wide: 25,877
• Since beginning of last month:
  • Site-wide: 122,719

Remdesivir Metabolite GS-441524 Efficiently Inhibits SARS-CoV-2 Infection in Mouse Model

• Downloaded 1,713 times
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  • Site-wide: 12,541
  • In pharmacology and toxicology: 72
• Year to date:
  • Site-wide: 3,716
• Since beginning of last month:
  • Site-wide: 6,754

Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs

• Downloaded 1,493 times
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  • Site-wide: 15,522
  • In developmental biology: 230
• Year to date:
  • Site-wide: 2,986
• Since beginning of last month:
  • Site-wide: 239

Human IL-2 receptor β mutations associated with defects in immunity and peripheral tolerance

• Downloaded 1,304 times
• Download rankings, all-time:
  • Site-wide: 19,060
  • In immunology: 664
• Year to date:
  • Site-wide: 35,611
• Since beginning of last month:
  • Site-wide: 117,635

An atlas of infiltrated B-lymphocytes in breast cancer revealed by paired single-cell RNA-sequencing and antigen receptor profiling

• Downloaded 1,236 times
• Download rankings, all-time:
  • Site-wide: 20,667
  • In immunology: 720
• Year to date:
  • Site-wide: 88,807
• Since beginning of last month:
  • Site-wide: 121,512

Comprehensive mapping of SARS-CoV-2 interactions in vivo reveals functional virus-host interactions

• Downloaded 1,204 times
• Download rankings, all-time:
  • Site-wide: 21,531
  • In genomics: 2,004
• Year to date:
  • Site-wide: 4,042
• Since beginning of last month:
  • Site-wide: 29,338

Multi-omics approach identifies novel age-, time- and treatment-related immunopathological signatures in MIS-C and pediatric COVID-19

• Downloaded 1,188 times
• Download rankings, all-time:
  • Site-wide: 21,965
  • In infectious diseases: 2,154
• Year to date:
  • Site-wide: 4,130
• Since beginning of last month:
  • Site-wide: 1,016

The polyploid state plays a tumor suppressive role in the liver

• Downloaded 1,179 times
• Download rankings, all-time:
  • Site-wide: 22,214
  • In cancer biology: 531
• Year to date:
  • Site-wide: 93,609
• Since beginning of last month:
  • Site-wide: 63,035

Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation

• Downloaded 1,154 times
• Download rankings, all-time:
  • Site-wide: 22,937
  • In neuroscience: 2,813
• Year to date:
  • Site-wide: 103,026
• Since beginning of last month:
  • Site-wide: 124,489

Hierarchical Domain Structure Reveals the Divergence of Activity among TADs and Boundaries

• Downloaded 1,119 times
• Download rankings, all-time:
  • Site-wide: 24,032
  • In bioinformatics: 2,701
• Year to date:
  • Site-wide: 129,658
• Since beginning of last month:
  • Site-wide: 120,575

The origin of domestication genes in goats

• Downloaded 1,110 times
• Download rankings, all-time:
  • Site-wide: 24,374
  • In genomics: 2,225
• Year to date:
  • Site-wide: 70,624
• Since beginning of last month:
  • Site-wide: 123,070

Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns

• Downloaded 1,101 times
• Download rankings, all-time:
  • Site-wide: 24,684
  • In neuroscience: 3,034
• Year to date:
  • Site-wide: 20,247
• Since beginning of last month:
  • Site-wide: 32,604

An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis

• Downloaded 1,067 times
• Download rankings, all-time:
  • Site-wide: 25,890
  • In genomics: 2,334
• Year to date:
  • Site-wide: 59,677
• Since beginning of last month:
  • Site-wide: 54,238

S3norm: simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data

• Downloaded 1,059 times
• Download rankings, all-time:
  • Site-wide: 26,178
  • In bioinformatics: 2,916
• Year to date:
  • Site-wide: 60,827
• Since beginning of last month:
  • Site-wide: 120,706

Structural basis of Mycobacterium tuberculosis transcription and transcription inhibition

• Downloaded 1,036 times
• Download rankings, all-time:
  • Site-wide: 27,047
  • In molecular biology: 723
• Year to date:
  • Site-wide: 138,924
• Since beginning of last month:
  • Site-wide: 135,233

Neurobehavioural Correlates of Obesity are Largely Heritable

• Downloaded 1,034 times
• Download rankings, all-time:
  • Site-wide: 27,126
  • In neuroscience: 3,395
• Year to date:
  • Site-wide: 141,229
• Since beginning of last month:
  • Site-wide: 157,494

QUBIC2: A novel biclustering algorithm for large-scale bulk RNA-sequencing and single-cell RNA-sequencing data analysis

• Downloaded 1,010 times
• Download rankings, all-time:
  • Site-wide: 28,107
  • In bioinformatics: 3,119
• Year to date:
  • Site-wide: 92,537
• Since beginning of last month:
  • Site-wide: 77,936

Gene modules associated with human diseases revealed by network analysis

• Downloaded 995 times
• Download rankings, all-time:
  • Site-wide: 28,707
  • In systems biology: 563
• Year to date:
  • Site-wide: 47,188
• Since beginning of last month:
  • Site-wide: 51,746

First demonstration of the FLASH effect with ultrahigh dose-rate high-energy X-rays

• Downloaded 989 times
• Download rankings, all-time:
  • Site-wide: 28,932
  • In cancer biology: 727
• Year to date:
  • Site-wide: 6,839
• Since beginning of last month:
  • Site-wide: 6,799

Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals

• Downloaded 979 times
• Download rankings, all-time:
  • Site-wide: 29,368
  • In cancer biology: 753
• Year to date:
  • Site-wide: 61,923
• Since beginning of last month:
  • Site-wide: 62,922

"CapZyme-Seq" comprehensively defines promoter-sequence determinants for RNA 5' capping with NAD+

• Downloaded 965 times
• Download rankings, all-time:
  • Site-wide: 30,026
  • In biochemistry: 709
• Year to date:
  • Site-wide: 105,191
• Since beginning of last month:
  • Site-wide: 141,856

Anatomical And Functional Organization Of The Human Substantia Nigra And Its Connections

• Downloaded 961 times
• Download rankings, all-time:
  • Site-wide: 30,177
  • In neuroscience: 3,853
• Year to date:
  • Site-wide: 94,655
• Since beginning of last month:
  • Site-wide: 63,392

A Novel AuNPs-based Glucose Oxidase Mimic with Enhanced Activity and Selectivity Constructed by Molecular Imprinting and O2-Containing Nanoemulsion Embedding

• Downloaded 941 times
• Download rankings, all-time:
  • Site-wide: 31,165
  • In biochemistry: 750
• Year to date:
  • Site-wide: 50,066
• Since beginning of last month:
  • Site-wide: 40,445

Bayesian Modeling of Epigenetic Variation in Multiple Human Cell Types

• Downloaded 908 times
• Download rankings, all-time:
  • Site-wide: 32,858
  • In bioinformatics: 3,583
• Year to date:
  • Site-wide: 117,611
• Since beginning of last month:
  • Site-wide: 91,351

Diffusion Tensor Tractography of Brainstem Fibers and Its Application in Pain

• Downloaded 893 times
• Download rankings, all-time:
  • Site-wide: 33,679
  • In neuroscience: 4,388
• Year to date:
  • Site-wide: 46,821
• Since beginning of last month:
  • Site-wide: 111,767

Progressive domain segregation in early embryonic development and underlying correlation to genetic and epigenetic changes

• Downloaded 876 times
• Download rankings, all-time:
  • Site-wide: 34,560
  • In developmental biology: 691
• Year to date:
  • Site-wide: 49,266
• Since beginning of last month:
  • Site-wide: 54,434

Unraveling reproducible dynamic states of individual brain functional parcellation

• Downloaded 874 times
• Download rankings, all-time:
  • Site-wide: 34,686
  • In neuroscience: 4,540
• Year to date:
  • Site-wide: 126,061
• Since beginning of last month:
  • Site-wide: 136,072

Functional Annotation of Human Cognitive States using Deep Graph Convolution

• Downloaded 848 times
• Download rankings, all-time:
  • Site-wide: 36,199
  • In neuroscience: 4,784
• Year to date:
  • Site-wide: 35,155
• Since beginning of last month:
  • Site-wide: 35,674

Snapshot: clustering and visualizing epigenetic history during cell differentiation

• Downloaded 797 times
• Download rankings, all-time:
  • Site-wide: 39,667
  • In bioinformatics: 4,215
• Year to date:
  • Site-wide: 106,662
• Since beginning of last month:
  • Site-wide: 70,562

LTMG: A novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data

• Downloaded 705 times
• Download rankings, all-time:
  • Site-wide: 47,169
  • In bioinformatics: 4,858
• Year to date:
  • Site-wide: 72,235
• Since beginning of last month:
  • Site-wide: 81,883

Treatment with human umbilical cord-derived mesenchymal stem cells for COVID-19 patients with lung damage: a randomised, double-blind, placebo controlled phase 2 trial

• Downloaded 686 times
• Download rankings, all-time:
  • Site-wide: 48,988
  • In infectious diseases: 3,281
• Year to date:
  • Site-wide: 29,788
• Since beginning of last month:
  • Site-wide: 31,829

Dimensionality reduction by UMAP reinforces sample heterogeneity analysis in bulk transcriptomic data

• Downloaded 680 times
• Download rankings, all-time:
  • Site-wide: 49,565
  • In bioinformatics: 5,037
• Year to date:
  • Site-wide: 9,756
• Since beginning of last month:
  • Site-wide: 49,021

Potent SARS-CoV-2 neutralizing antibodies selected from a human antibody library constructed decades ago

• Downloaded 666 times
• Download rankings, all-time:
  • Site-wide: 51,063
  • In microbiology: 3,108
• Year to date:
  • Site-wide: 29,901
• Since beginning of last month:
  • Site-wide: 57,939

Membrane potential regulates the dynamic localisation of mammalian proteasomes

• Downloaded 659 times
• Download rankings, all-time:
  • Site-wide: 51,792
  • In cell biology: 2,213
• Year to date:
  • Site-wide: 83,191
• Since beginning of last month:
  • Site-wide: 86,100

Prime editing efficiently generates W542L and S621I double mutations in two ALS genes in maize

• Downloaded 658 times
• Download rankings, all-time:
  • Site-wide: 51,858
  • In plant biology: 1,156
• Year to date:
  • Site-wide: 90,723
• Since beginning of last month:
  • Site-wide: 119,115

Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli

• Downloaded 600 times
• Download rankings, all-time:
  • Site-wide: 58,543
  • In biochemistry: 1,547
• Year to date:
  • Site-wide: 11,962
• Since beginning of last month:
  • Site-wide: 69,288

Genetic regulation of OAS1 nonsense-mediated decay underlies association with risk of severe COVID-19

• Downloaded 593 times
• Download rankings, all-time:
  • Site-wide: 59,482
  • In genetic and genomic medicine: 283
• Year to date:
  • Site-wide: 12,182
• Since beginning of last month:
  • Site-wide: 13,083

IAV-CNN: a 2D convolutional neural network model to predict antigenic variants of influenza A virus

• Downloaded 577 times
• Download rankings, all-time:
  • Site-wide: 61,561
  • In bioinformatics: 5,990
• Year to date:
  • Site-wide: 54,365
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  • Site-wide: 67,097

Chromatin Interaction Neural Network (ChINN): A machine learning-based method for predicting chromatin interactions from DNA sequences

• Downloaded 573 times
• Download rankings, all-time:
  • Site-wide: 61,970
  • In bioinformatics: 6,019
• Year to date:
  • Site-wide: 14,055
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  • Site-wide: 68,895

A comprehensive temporal patterning gene network in Drosophila medulla neuroblasts revealed by single-cell RNA sequencing

• Downloaded 567 times
• Download rankings, all-time:
  • Site-wide: 62,780
  • In developmental biology: 1,514
• Year to date:
  • Site-wide: 13,043
• Since beginning of last month:
  • Site-wide: 21,709

Genome-wide RNA structure changes during human neurogenesis drive gene regulatory networks

• Downloaded 548 times
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  • Site-wide: 65,529
  • In molecular biology: 1,877
• Year to date:
  • Site-wide: 13,739
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  • Site-wide: 15,639

The Impact of Psychology Interventions on Changing Mental Health Status and Sleep Quality in University Students during the COVID-19 Pandemic

• Downloaded 541 times
• Download rankings, all-time:
  • Site-wide: 66,601
  • In public and global health: 991
• Year to date:
  • Site-wide: 29,429
• Since beginning of last month:
  • Site-wide: 25,356

Predicting the required pre-surgery blood volume in surgical patients based on machine learning

• Downloaded 534 times
• Download rankings, all-time:
  • Site-wide: 67,709
  • In hematology: 63
• Year to date:
  • Site-wide: 81,799
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  • Site-wide: 45,208

Biogenesis of a young, 22-nt microRNA in Phaseoleae species by precursor-programmed uridylation

• Downloaded 516 times
• Download rankings, all-time:
  • Site-wide: 70,392
  • In plant biology: 1,748
• Year to date:
  • Site-wide: 151,385
• Since beginning of last month:
  • Site-wide: 146,114

Accurate and Reproducible Functional Maps in 127 Human Cell Types via 2D Genome Segmentation

• Downloaded 507 times
• Download rankings, all-time:
  • Site-wide: 71,776
  • In genomics: 4,905
• Year to date:
  • Site-wide: 148,178
• Since beginning of last month:
  • Site-wide: 142,086

IFITM3 restricts human metapneumovirus infection

• Downloaded 501 times
• Download rankings, all-time:
  • Site-wide: 72,794
  • In immunology: 2,225
• Year to date:
  • Site-wide: 128,668
• Since beginning of last month:
  • Site-wide: 137,147

Structural basis for transcription initiation by bacterial ECF σ factors

• Downloaded 500 times
• Download rankings, all-time:
  • Site-wide: 73,006
  • In microbiology: 4,782
• Year to date:
  • Site-wide: 99,685
• Since beginning of last month:
  • Site-wide: 160,530

Circadian control of intrinsic heart rate via a sinus node clock and the pacemaker channel

• Downloaded 492 times
• Download rankings, all-time:
  • Site-wide: 74,297
  • In physiology: 517
• Year to date:
  • Site-wide: 111,307
• Since beginning of last month:
  • Site-wide: 91,280

The Incubation Period of Severe Acute Respiratory Syndrome Coronavirus 2:A Systematic Review

• Downloaded 487 times
• Download rankings, all-time:
  • Site-wide: 75,179
  • In epidemiology: 3,315
• Year to date:
  • Site-wide: 91,992
• Since beginning of last month:
  • Site-wide: 93,373

Decoding transcriptional regulation via a human gene expression predictor

• Downloaded 474 times
• Download rankings, all-time:
  • Site-wide: 77,499
  • In systems biology: 1,734
• Year to date:
  • Site-wide: 70,459
• Since beginning of last month:
  • Site-wide: 94,440

Clinical characteristics of Covid-19 patients with re-positive test results: an observational study

• Downloaded 460 times
• Download rankings, all-time:
  • Site-wide: 80,031
  • In public and global health: 1,144
• Year to date:
  • Site-wide: 89,995
• Since beginning of last month:
  • Site-wide: 64,695

Disrupting myeloid-specific LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation

• Downloaded 431 times
• Download rankings, all-time:
  • Site-wide: 85,752
  • In physiology: 663
• Year to date:
  • Site-wide: 146,366
• Since beginning of last month:
  • Site-wide: 150,216

Single-shot rAAV5-based Vaccine Provides Long-term Protective Immunity against SARS-CoV-2 and Its Variants

• Downloaded 427 times
• Download rankings, all-time:
  • Site-wide: 86,566
  • In immunology: 2,626
• Year to date:
  • Site-wide: 20,175
• Since beginning of last month:
  • Site-wide: 105,874

Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p

• Downloaded 426 times
• Download rankings, all-time:
  • Site-wide: 86,757
  • In microbiology: 5,817
• Year to date:
  • Site-wide: 58,361
• Since beginning of last month:
  • Site-wide: 68,328

Characterization of SARS-CoV-2 variants B.1.617.1 (Kappa), B.1.617.2 (Delta) and B.1.618 on cell entry, host range, and sensitivity to convalescent plasma and ACE2 decoy receptor

• Downloaded 426 times
• Download rankings, all-time:
  • Site-wide: 86,619
  • In microbiology: 5,816
• Year to date:
  • Site-wide: 20,299
• Since beginning of last month:
  • Site-wide: 23,155

The PRMT7-dependent methylation of shank2 modulates invasion-proliferation switching during breast cancer metastasis

• Downloaded 416 times
• Download rankings, all-time:
  • Site-wide: 88,794
  • In cancer biology: 2,643
• Year to date:
  • Site-wide: 87,720
• Since beginning of last month:
  • Site-wide: 124,878

Cancer SIGVAR: A semi-automated interpretation tool for germline variants of hereditary cancer-related genes

• Downloaded 406 times
• Download rankings, all-time:
  • Site-wide: 90,858
  • In genetics: 3,780
• Year to date:
  • Site-wide: 62,823
• Since beginning of last month:
  • Site-wide: 115,206

FPfilter: A false-positive-specific filter for whole-genome sequencing variant calling from GATK

• Downloaded 399 times
• Download rankings, all-time:
  • Site-wide: 92,403
  • In bioinformatics: 8,088
• Year to date:
  • Site-wide: 77,109
• Since beginning of last month:
  • Site-wide: 55,132

Kidney injury molecule-1 is a potential receptor for SARS-CoV-2

• Downloaded 396 times
• Download rankings, all-time:
  • Site-wide: 93,050
  • In cell biology: 4,288
• Year to date:
  • Site-wide: 41,166
• Since beginning of last month:
  • Site-wide: 68,457

Artificial intelligence assisted standard white light endoscopy accurately characters early colorectal cancer: a multicenter diagnostic study

• Downloaded 394 times
• Download rankings, all-time:
  • Site-wide: 93,486
  • In oncology: 189
• Year to date:
  • Site-wide: 76,096
• Since beginning of last month:
  • Site-wide: 67,795

Structural and mechanistic basis of reiterative transcription initiation

• Downloaded 389 times
• Download rankings, all-time:
  • Site-wide: 94,556
  • In molecular biology: 2,789
• Year to date:
  • Site-wide: 23,414
• Since beginning of last month:
  • Site-wide: 36,559

Müllerian-inhibiting substance (MIS) is both necessary and sufficient for testicular differentiation in Chinese soft-shelled turtle Pelodiscus sinensis

• Downloaded 381 times
• Download rankings, all-time:
  • Site-wide: 96,286
  • In developmental biology: 2,607
• Year to date:
  • Site-wide: 131,406
• Since beginning of last month:
  • Site-wide: 121,362

Progressive domain segregation in early embryonic development and underlying correlation to genetic and epigenetic changes

• Downloaded 379 times
• Download rankings, all-time:
  • Site-wide: 96,912
  • In developmental biology: 2,625
• Year to date:
  • Site-wide: 24,270
• Since beginning of last month:
  • Site-wide: 100,941

Transferability of Brain decoding using Graph Convolutional Networks

• Downloaded 376 times
• Download rankings, all-time:
  • Site-wide: 97,494
  • In neuroscience: 14,486
• Year to date:
  • Site-wide: 75,446
• Since beginning of last month:
  • Site-wide: 76,075

Diversity and biogeography of Woesearchaeota: A comprehensive analysis of multi-environment data

• Downloaded 346 times
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  • Site-wide: 104,591
  • In ecology: 3,070
• Year to date:
  • Site-wide: 67,096
• Since beginning of last month:
  • Site-wide: 99,325

Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of mouse hematopoietic cells

• Downloaded 345 times
• Download rankings, all-time:
  • Site-wide: 104,813
  • In genomics: 6,241
• Year to date:
  • Site-wide: 137,868
• Since beginning of last month:
  • Site-wide: 127,509

RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription

• Downloaded 333 times
• Download rankings, all-time:
  • Site-wide: 107,921
  • In biochemistry: 3,170
• Year to date:
  • Site-wide: 149,214
• Since beginning of last month:
  • Site-wide: 126,080

Complete depletion of Arabidopsis linker histones impairs the correlations among chromatin compartmentalization, DNA methylation and gene expression

• Downloaded 311 times
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  • Site-wide: 113,460
  • In plant biology: 3,081
• Year to date:
  • Site-wide: 32,470
• Since beginning of last month:
  • Site-wide: 43,127

A Kozak-related non-coding deletion effectively increases B.1.1.7 transmissibility

• Downloaded 310 times
• Download rankings, all-time:
  • Site-wide: 113,772
  • In evolutionary biology: 5,622
• Year to date:
  • Site-wide: 32,529
• Since beginning of last month:
  • Site-wide: 39,943

Deep learning models of cognitive processes constrained by human brain connectomes

• Downloaded 310 times
• Download rankings, all-time:
  • Site-wide: 113,762
  • In neuroscience: 17,018
• Year to date:
  • Site-wide: 32,572
• Since beginning of last month:
  • Site-wide: 2,484

Synonymous SNPs of viral genes facilitate virus to escape host antiviral RNAi immunity

• Downloaded 309 times
• Download rankings, all-time:
  • Site-wide: 113,897
  • In pathology: 624
• Year to date:
  • Site-wide: 136,776
• Since beginning of last month:
  • Site-wide: 101,613

Direct prediction of regulatory elements from partial data without imputation

• Downloaded 303 times
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  • Site-wide: 115,426
  • In bioinformatics: 9,489
• Year to date:
  • Site-wide: 164,253
• Since beginning of last month:
  • Site-wide: 162,899

Helicobacter pylori-induced adrenomedullin modulates IFN-γ-producing T-cell responses and contribute to gastritis

• Downloaded 291 times
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  • Site-wide: 118,604
  • In immunology: 3,550
• Year to date:
  • Site-wide: 143,945
• Since beginning of last month:
  • Site-wide: 124,572

Integrative framework of cross-module deep biomarker for the prognosis of clear cell renal cell carcinoma: A retrospective TCGA project

• Downloaded 287 times
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  • Site-wide: 119,750
  • In bioinformatics: 9,754
• Year to date:
  • Site-wide: 133,635
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  • Site-wide: 97,493

Uncovering the Genetic Profiles Underlying the Intrinsic Organization of the Human Cerebellum

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Synergistic application of continuous granulation and selective laser sintering 3D printing for the development of pharmaceutical dosage forms with enhanced dissolution rates and physical properties

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Model-based cellular kinetic analysis of SARS-CoV-2 infection: different immune response modes and treatment strategies

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MS2 RNA aptamer enhances prime editing in rice

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The adenosine analogue prodrug ATV006 is orally bioavailable and has potent preclinical efficacy against SARS-CoV-2 and its variants

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Accurate Name Entity Recognition for Biomedical Literatures: A Combined High-quality Manual Annotation and Deep-learning Natural Language Processing Study

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Predicting Collaborative Learning Quality through Physiological Synchrony Recorded by Wearable Biosensors

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Crl activates transcription by stabilizing the active conformation of the master stress factor σS

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Cortical microinfarcts potentiate recurrent ischemic injury through NLRP3-dependent trained immunity

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Chromatin changes in PIF-regulated genes parallel their rapid transcriptional response to light

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The role of swnR gene on the biosynthesis pathway of the swainsonine in Metarhizium anisopliae

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Inhibition of USP4 attenuates epithelial-mesenchymal transition of renal tubular epithelial cells by TβRI

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Netrins and receptors control Drosophila optic lobe organization and transmedullary neuron axon targeting

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S3V2-IDEAS: a package for normalizing, denoising and integrating epigenomic datasets across different cell types

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Potential mechanisms of action of celastrol against rheumatoid arthritis: transcriptomic and proteomic analysis

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Evaluation of azithromycin or hydroxychloroquine plus azithromycin combination therapy on cardiac conduction and function in guinea pigs

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Dysbiotic oral and gut viromes in untreated and treated rheumatoid arthritis patients

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A Potential Novel COVID-19 Vaccine With RBD-HR1/HR2 Hexamer Structure

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The first crested duck genome reveals clues to genetic compensation and crest cushion formation

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BAI-Net: Individualized Anatomical Human Cerebral Cartography using Graph Convolutional Network

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Representational learning of brain responses in executive function and higher-order cognition using deep graph convolutions

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Predicting Axillary Lymph Node Metastasis in Early Breast Cancer Using Deep Learning on Primary Tumor Biopsy Slides

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Genome-wide H3K9 Acetylation Level Increases with Age-Dependent Senescence of Flag Leaf in Rice (Oryza sativa)

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