Author: Alex Sigal
- ORCiD: http://orcid.org/0000-0001-8571-2004
- Most recently observed institution: Africa Health Research Institute, University of KwaZulu-Natal
Rankings
- All-time downloads: 190,410 (rank: 651 )
- Categories:
- bioinformatics: 638 (rank: 27,261 (tie) )
- epidemiology: 37,667 (rank: 657 )
- evolutionary biology: 4,387 (rank: 1,011 (tie) )
- hiv aids: 2,864 (rank: 17 (tie) )
- immunology: 1,339 (rank: 11,487 (tie) )
- infectious diseases: 100,834 (rank: 517 )
- microbiology: 22,990 (rank: 966 )
- molecular biology: 599 (rank: 15,000 (tie) )
Downloads per author, site-wide
Preprints
HIV skews the SARS-CoV-2 B cell response toward an extrafollicular maturation pathway
immunology more details view paperNo download data for this paper yet.
Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa
epidemiology more details view paper- Downloaded 38,015 times
- Download rankings, all-time:
- Site-wide: 255
- In epidemiology: 56
- Year to date:
- Site-wide: 743
- Since beginning of last month:
- Site-wide: 1,015
SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron
infectious diseases more details view paper- Downloaded 25,081 times
- Download rankings, all-time:
- Site-wide: 415
- In infectious diseases: 159
- Year to date:
- Site-wide: 82
- Since beginning of last month:
- Site-wide: 2,758
The continuous evolution of SARS-CoV-2 in South Africa: a new lineage with rapid accumulation of mutations of concern and global detection
infectious diseases more details view paper- Downloaded 18,092 times
- Download rankings, all-time:
- Site-wide: 605
- In infectious diseases: 223
- Year to date:
- Site-wide: 2,916
- Since beginning of last month:
- Site-wide: 3,789
SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion
microbiology more details view paper- Downloaded 17,673 times
- Download rankings, all-time:
- Site-wide: 620
- In microbiology: 71
- Year to date:
- Site-wide: 91
- Since beginning of last month:
- Site-wide: 1,045
Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity
infectious diseases more details view paper- Downloaded 14,702 times
- Download rankings, all-time:
- Site-wide: 780
- In infectious diseases: 272
- Year to date:
- Site-wide: 4,079
- Since beginning of last month:
- Site-wide: 4,683
SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection
infectious diseases more details view paper- Downloaded 12,822 times
- Download rankings, all-time:
- Site-wide: 932
- In infectious diseases: 352
- Year to date:
- Site-wide: 202
- Since beginning of last month:
- Site-wide: 521
A meta-analysis of Early Results to predict Vaccine efficacy against Omicron
infectious diseases more details view paper- Downloaded 10,480 times
- Download rankings, all-time:
- Site-wide: 1,206
- In infectious diseases: 393
- Year to date:
- Site-wide: 313
- Since beginning of last month:
- Site-wide: 2,141
Omicron sub-lineages BA.4/BA.5 escape BA.1 infection elicited neutralizing immunity
infectious diseases more details view paper- Downloaded 8,756 times
- Download rankings, all-time:
- Site-wide: 1,508
- In infectious diseases: None
- Year to date:
- Site-wide: 107
- Since beginning of last month:
- Site-wide: 9
SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity
infectious diseases more details view paper- Downloaded 6,200 times
- Download rankings, all-time:
- Site-wide: 2,368
- In infectious diseases: 646
- Year to date:
- Site-wide: 2,438
- Since beginning of last month:
- Site-wide: 7,815
Escape of SARS-CoV-2 501Y.V2 variants from neutralization by convalescent plasma
infectious diseases more details view paper- Downloaded 6,136 times
- Download rankings, all-time:
- Site-wide: 2,404
- In infectious diseases: 640
- Year to date:
- Site-wide: 13,881
- Since beginning of last month:
- Site-wide: 13,111
Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant
infectious diseases more details view paper- Downloaded 5,711 times
- Download rankings, all-time:
- Site-wide: 2,634
- In infectious diseases: 754
- Year to date:
- Site-wide: 183
- Since beginning of last month:
- Site-wide: 2,132
Persistent SARS-CoV-2 infection and intra-host evolution in association with advanced HIV infection
infectious diseases more details view paper- Downloaded 5,249 times
- Download rankings, all-time:
- Site-wide: 2,973
- In infectious diseases: 771
- Year to date:
- Site-wide: 1,317
- Since beginning of last month:
- Site-wide: 3,807
Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function
evolutionary biology more details view paper- Downloaded 4,667 times
- Download rankings, all-time:
- Site-wide: 3,472
- In evolutionary biology: 67
- Year to date:
- Site-wide: 212
- Since beginning of last month:
- Site-wide: 2,342
SARS-CoV-2 cell-to-cell spread occurs rapidly and is insensitive to antibody neutralization
microbiology more details view paper- Downloaded 3,192 times
- Download rankings, all-time:
- Site-wide: 5,957
- In microbiology: 373
- Year to date:
- Site-wide: 15,721
- Since beginning of last month:
- Site-wide: 60,375
HIV status alters disease severity and immune cell responses in beta variant SARS-CoV-2 infection wave
hiv aids more details view paper- Downloaded 2,436 times
- Download rankings, all-time:
- Site-wide: 8,832
- In hiv aids: 4
- Year to date:
- Site-wide: 23,128
- Since beginning of last month:
- Site-wide: 34,980
Major new lineages of SARS-CoV-2 emerge and spread in South Africa during lockdown.
infectious diseases more details view paper- Downloaded 1,415 times
- Download rankings, all-time:
- Site-wide: 19,988
- In infectious diseases: 2,160
- Year to date:
- Site-wide: 66,835
- Since beginning of last month:
- Site-wide: 41,390
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
microbiology more details view paper- Downloaded 1,310 times
- Download rankings, all-time:
- Site-wide: 22,522
- In microbiology: 1,428
- Year to date:
- Site-wide: 8,740
- Since beginning of last month:
- Site-wide: 17,278
Naturally-acquired immunity in Syrian Golden Hamsters provides protection from re-exposure to emerging heterosubtypic SARS-CoV-2 variants B.1.1.7 and B.1.351
microbiology more details view paper- Downloaded 830 times
- Download rankings, all-time:
- Site-wide: 44,788
- In microbiology: 2,603
- Year to date:
- Site-wide: 88,409
- Since beginning of last month:
- Site-wide: 56,548
Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains
immunology more details view paper- Downloaded 799 times
- Download rankings, all-time:
- Site-wide: 47,389
- In immunology: 1,517
- Year to date:
- Site-wide: 70,623
- Since beginning of last month:
- Site-wide: 36,505
The importance of time post-vaccination in determining the decrease in vaccine efficacy against SARS-CoV-2 variants of concern
epidemiology more details view paper- Downloaded 752 times
- Download rankings, all-time:
- Site-wide: 51,679
- In epidemiology: 2,467
- Year to date:
- Site-wide: 77,193
- Since beginning of last month:
- Site-wide: 82,394
HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells
microbiology more details view paper- Downloaded 663 times
- Download rankings, all-time:
- Site-wide: 61,605
- In microbiology: 3,640
- Year to date:
- Site-wide: 72,364
- Since beginning of last month:
- Site-wide: 155,002
The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes
microbiology more details view paper- Downloaded 619 times
- Download rankings, all-time:
- Site-wide: 67,340
- In microbiology: None
- Year to date:
- Site-wide: 3,570
- Since beginning of last month:
- Site-wide: 12,901
Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA
molecular biology more details view paper- Downloaded 603 times
- Download rankings, all-time:
- Site-wide: 69,814
- In molecular biology: 1,802
- Year to date:
- Site-wide: 190,491
- Since beginning of last month:
- Site-wide: 189,628
Development of highly potent neutralising nanobodies against multiple SARS-CoV-2 variants including the variant of concern B.1.351
immunology more details view paper- Downloaded 599 times
- Download rankings, all-time:
- Site-wide: 70,432
- In immunology: 2,057
- Year to date:
- Site-wide: 80,636
- Since beginning of last month:
- Site-wide: 109,946
Immunogenicity of the Ad26.CoV2.S vaccine in people living with HIV
hiv aids more details view paper- Downloaded 587 times
- Download rankings, all-time:
- Site-wide: 72,183
- In hiv aids: 43
- Year to date:
- Site-wide: 33,154
- Since beginning of last month:
- Site-wide: 44,473
Beta infection combined with Pfizer BNT162b2 vaccination leads to broadened neutralizing immunity against Omicron
infectious diseases more details view paper- Downloaded 504 times
- Download rankings, all-time:
- Site-wide: 86,758
- In infectious diseases: None
- Year to date:
- Site-wide: 4,867
- Since beginning of last month:
- Site-wide: 24,900
HIV cell-to-cell spread slows evolution of drug resistance
evolutionary biology more details view paper- Downloaded 481 times
- Download rankings, all-time:
- Site-wide: 91,350
- In evolutionary biology: 4,979
- Year to date:
- Site-wide: 32,768
- Since beginning of last month:
- Site-wide: 35,000
Aggregated Mycobacterium tuberculosis enhances the inflammatory response
microbiology more details view paper- Downloaded 396 times
- Download rankings, all-time:
- Site-wide: 111,104
- In microbiology: 8,160
- Year to date:
- Site-wide: 62,730
- Since beginning of last month:
- Site-wide: 20,679
The CNS in the face of ART contains T cell origin HIV which can lead to drug resistance
microbiology more details view paper- Downloaded 383 times
- Download rankings, all-time:
- Site-wide: 114,470
- In microbiology: 7,283
- Year to date:
- Site-wide: 185,337
- Since beginning of last month:
- Site-wide: 175,624
Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death
bioinformatics more details view paper- Downloaded 359 times
- Download rankings, all-time:
- Site-wide: 120,968
- In bioinformatics: 9,395
- Year to date:
- Site-wide: 163,973
- Since beginning of last month:
- Site-wide: 131,156
Interference with HIV infection of the first cell is essential for viral clearance in a pre-exposure prophylaxis model
bioinformatics more details view paper- Downloaded 308 times
- Download rankings, all-time:
- Site-wide: 135,576
- In bioinformatics: 10,275
- Year to date:
- Site-wide: 165,991
- Since beginning of last month:
- Site-wide: 164,663
Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology
microbiology more details view paper- Downloaded 226 times
- Download rankings, all-time:
- Site-wide: 159,894
- In microbiology: 11,311
- Year to date:
- Site-wide: 131,785
- Since beginning of last month:
- Site-wide: 99,755
Complementation can maintain a quasispecies of drug sensitive and resistant HIV
evolutionary biology more details view paper- Downloaded 200 times
- Download rankings, all-time:
- Site-wide: 166,514
- In evolutionary biology: 7,354
- Year to date:
- Site-wide: 158,775
- Since beginning of last month:
- Site-wide: 151,954
Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition
infectious diseases more details view paper- Downloaded 164 times
- Download rankings, all-time:
- Site-wide: 175,257
- In infectious diseases: None
- Year to date:
- Site-wide: 25,490
- Since beginning of last month:
- Site-wide: 37,304
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