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Author: Alex Sigal

Rankings

  • All-time downloads: 80,598 (rank: 1,999 )
  • Categories:
    • bioinformatics: 542 (rank: 26,333 (tie) )
    • epidemiology: 34,957 (rank: 523 )
    • evolutionary biology: 454 (rank: 15,831 (tie) )
    • hiv aids: 1,638 (rank: 39 (tie) )
    • immunology: 1,004 (rank: 11,949 (tie) )
    • infectious diseases: 37,175 (rank: 1,484 )
    • microbiology: 4,237 (rank: 3,754 )
    • molecular biology: 591 (rank: 12,077 (tie) )

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Preprints

Divergence of delta and beta variants and SARS-CoV-2 evolved in prolonged infection into distinct serological phenotypes

infectious diseases more details view paper

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Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa

epidemiology more details view paper
  • Downloaded 34,429 times
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    • Site-wide: 218
    • In epidemiology: 46
  • Year to date:
    • Site-wide: 56
  • Since beginning of last month:
    • Site-wide: 151

The continuous evolution of SARS-CoV-2 in South Africa: a new lineage with rapid accumulation of mutations of concern and global detection

infectious diseases more details view paper
  • Downloaded 15,168 times
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    • Site-wide: 551
    • In infectious diseases: 196
  • Year to date:
    • Site-wide: 130
  • Since beginning of last month:
    • Site-wide: 14

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

infectious diseases more details view paper
  • Downloaded 13,609 times
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    • Site-wide: 646
    • In infectious diseases: 221
  • Year to date:
    • Site-wide: 144
  • Since beginning of last month:
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Escape of SARS-CoV-2 501Y.V2 variants from neutralization by convalescent plasma

infectious diseases more details view paper
  • Downloaded 5,362 times
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    • Site-wide: 2,183
    • In infectious diseases: 541
  • Year to date:
    • Site-wide: 412
  • Since beginning of last month:
    • Site-wide: 66,274

SARS-CoV-2 cell-to-cell spread occurs rapidly and is insensitive to antibody neutralization

microbiology more details view paper
  • Downloaded 2,535 times
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    • Site-wide: 6,282
    • In microbiology: 385
  • Year to date:
    • Site-wide: 983
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Persistent SARS-CoV-2 infection and intra-host evolution in association with advanced HIV infection

infectious diseases more details view paper
  • Downloaded 1,850 times
  • Download rankings, all-time:
    • Site-wide: 9,952
    • In infectious diseases: 1,376
  • Year to date:
    • Site-wide: 1,453
  • Since beginning of last month:
    • Site-wide: 578

HIV status alters disease severity and immune cell responses in beta variant SARS-CoV-2 infection wave

hiv aids more details view paper
  • Downloaded 1,638 times
  • Download rankings, all-time:
    • Site-wide: 11,948
    • In hiv aids: 5
  • Year to date:
    • Site-wide: 2,343
  • Since beginning of last month:
    • Site-wide: 49,589

Major new lineages of SARS-CoV-2 emerge and spread in South Africa during lockdown.

infectious diseases more details view paper
  • Downloaded 1,186 times
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    • Site-wide: 19,305
    • In infectious diseases: 1,901
  • Year to date:
    • Site-wide: 6,565
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    • Site-wide: 95,771

Naturally-acquired immunity in Syrian Golden Hamsters provides protection from re-exposure to emerging heterosubtypic SARS-CoV-2 variants B.1.1.7 and B.1.351

microbiology more details view paper
  • Downloaded 675 times
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    • Site-wide: 42,918
    • In microbiology: 2,593
  • Year to date:
    • Site-wide: 5,865
  • Since beginning of last month:
    • Site-wide: 128,401

Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA

molecular biology more details view paper
  • Downloaded 591 times
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    • Site-wide: 50,822
    • In molecular biology: 1,445
  • Year to date:
    • Site-wide: 129,533
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    • Site-wide: 58,424

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

immunology more details view paper
  • Downloaded 573 times
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    • Site-wide: 52,899
    • In immunology: 1,612
  • Year to date:
    • Site-wide: 7,464
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    • Site-wide: 93,915

The importance of time post-vaccination in determining the decrease in vaccine efficacy against SARS-CoV-2 variants of concern

epidemiology more details view paper
  • Downloaded 528 times
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    • Site-wide: 58,429
    • In epidemiology: 2,640
  • Year to date:
    • Site-wide: 8,465
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    • Site-wide: 72,594

Development of highly potent neutralising nanobodies against multiple SARS-CoV-2 variants including the variant of concern B.1.351

immunology more details view paper
  • Downloaded 431 times
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    • Site-wide: 72,906
    • In immunology: 2,189
  • Year to date:
    • Site-wide: 11,403
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    • Site-wide: 131,510

HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells

microbiology more details view paper
  • Downloaded 399 times
  • Download rankings, all-time:
    • Site-wide: 78,492
    • In microbiology: 5,309
  • Year to date:
    • Site-wide: 12,706
  • Since beginning of last month:
    • Site-wide: 119,724

The CNS in the face of ART contains T cell origin HIV which can lead to drug resistance

microbiology more details view paper
  • Downloaded 329 times
  • Download rankings, all-time:
    • Site-wide: 92,778
    • In microbiology: 6,467
  • Year to date:
    • Site-wide: 129,503
  • Since beginning of last month:
    • Site-wide: 102,962

HIV cell-to-cell spread slows evolution of drug resistance

evolutionary biology more details view paper
  • Downloaded 313 times
  • Download rankings, all-time:
    • Site-wide: 96,388
    • In evolutionary biology: 4,956
  • Year to date:
    • Site-wide: 44,967
  • Since beginning of last month:
    • Site-wide: 16,084

Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death

bioinformatics more details view paper
  • Downloaded 304 times
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    • Site-wide: 98,494
    • In bioinformatics: 8,492
  • Year to date:
    • Site-wide: 150,643
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    • Site-wide: None

Interference with HIV infection of the first cell is essential for viral clearance in a pre-exposure prophylaxis model

bioinformatics more details view paper
  • Downloaded 238 times
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    • Site-wide: 114,492
    • In bioinformatics: 9,471
  • Year to date:
    • Site-wide: 149,199
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    • Site-wide: 106,353

Aggregated Mycobacterium tuberculosis enhances the inflammatory response

microbiology more details view paper
  • Downloaded 195 times
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    • Site-wide: 125,081
    • In microbiology: 9,285
  • Year to date:
    • Site-wide: 33,522
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    • Site-wide: 43,671

Complementation can maintain a quasispecies of drug sensitive and resistant HIV

evolutionary biology more details view paper
  • Downloaded 141 times
  • Download rankings, all-time:
    • Site-wide: 137,439
    • In evolutionary biology: 6,756
  • Year to date:
    • Site-wide: 124,454
  • Since beginning of last month:
    • Site-wide: 65,844

Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology

microbiology more details view paper
  • Downloaded 104 times
  • Download rankings, all-time:
    • Site-wide: 144,936
    • In microbiology: 11,054
  • Year to date:
    • Site-wide: 65,418
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