Author: Marcella Rietschel

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 997
  • In genetics: 26
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  • Site-wide: 41,876

The genetic architecture of the human cerebral cortex

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  • Site-wide: 1,214
  • In genetics: 32
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  • Site-wide: 18,048
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  • Site-wide: 29,495

Genomewide association study identifies 30 loci associated with bipolar disorder

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  • Site-wide: 1,364
  • In genetics: 40
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  • Site-wide: 23,172
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  • Site-wide: 24,602

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

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  • Site-wide: 2,833
  • In systems biology: 40
• Year to date:
  • Site-wide: 68,430
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  • Site-wide: 102,472

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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  • Site-wide: 5,124
  • In psychiatry and clinical psychology: 20
• Year to date:
  • Site-wide: 1,536
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  • Site-wide: 6,250

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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  • Site-wide: 9,210
  • In genetics: 400
• Year to date:
  • Site-wide: 83,860
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  • Site-wide: 59,084

Dynamics of Brain Structure and its Genetic Architecture over the Lifespan

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  • Site-wide: 9,390
  • In genetics: 411
• Year to date:
  • Site-wide: 17,844
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 9,878
  • In genetics: 444
• Year to date:
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  • Site-wide: 83,431

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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  • Site-wide: 10,347
  • In genetics: 465
• Year to date:
  • Site-wide: 73,645
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  • Site-wide: 22,775

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

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  • Site-wide: 11,797
  • In genetics: 540
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  • Site-wide: 20,100
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  • Site-wide: 14,923

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 13,460
  • In genomics: 1,385
• Year to date:
  • Site-wide: 100,914
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  • Site-wide: 105,711

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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  • Site-wide: 15,844
  • In genetics: 733
• Year to date:
  • Site-wide: 5,087
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  • Site-wide: 2,776

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

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  • Site-wide: 16,220
  • In genetics: 757
• Year to date:
  • Site-wide: 126,251
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  • Site-wide: 141,036

Genomic architecture of human neuroanatomical diversity

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  • Site-wide: 18,983
  • In neuroscience: 2,320
• Year to date:
  • Site-wide: 117,280
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  • Site-wide: 143,132

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

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  • Site-wide: 19,392
  • In neurology: 39
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  • Site-wide: 2,348
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  • Site-wide: 3,164

Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

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  • Site-wide: 25,201
  • In genetics: 1,163
• Year to date:
  • Site-wide: 18,196
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Pharmacogenetics of antidepressant response: a polygenic approach

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  • Site-wide: 27,324
  • In genetics: 1,266
• Year to date:
  • Site-wide: 101,945
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  • Site-wide: 92,365

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 866 times
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  • Site-wide: 29,560
  • In genetics: 1,366
• Year to date:
  • Site-wide: 96,961
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  • Site-wide: 78,249

Polygenic scores for major depressive disorder and depressive symptoms predict response to lithium in patients with bipolar disorder

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  • Site-wide: 31,699
  • In genomics: 2,787
• Year to date:
  • Site-wide: 90,004
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  • Site-wide: 59,291

Planar cell polarity pathway and development of the human visual cortex

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  • Site-wide: 32,615
  • In neuroscience: 4,313
• Year to date:
  • Site-wide: 72,575
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  • Site-wide: 141,941

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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  • Site-wide: 34,544
  • In genetics: 1,587
• Year to date:
  • Site-wide: 24,405
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  • Site-wide: 59,369

Generative network models identify biological mechanisms of altered structural brain connectivity in schizophrenia

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  • Site-wide: 35,986
  • In neuroscience: 4,844
• Year to date:
  • Site-wide: 84,135
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  • Site-wide: 106,346

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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  • Site-wide: 37,841
  • In genetics: 1,722
• Year to date:
  • Site-wide: 109,809
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  • Site-wide: 110,924

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

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  • Site-wide: 41,260
  • In neuroscience: 5,708
• Year to date:
  • Site-wide: 59,386
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  • Site-wide: 122,697

Higher genetic risk for schizophrenia is associated with living in urban and populated areas

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  • Site-wide: 41,306
  • In genetics: 1,872
• Year to date:
  • Site-wide: 104,656
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  • Site-wide: 110,979

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

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  • Site-wide: 47,349
  • In genomics: 3,716
• Year to date:
  • Site-wide: 125,551
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  • Site-wide: 41,567

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

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  • Site-wide: 48,336
  • In genomics: 3,762
• Year to date:
  • Site-wide: 73,092
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  • Site-wide: 40,379

High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis

• Downloaded 585 times
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  • Site-wide: 49,914
  • In genetics: 2,234
• Year to date:
  • Site-wide: 128,040
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  • Site-wide: 111,099

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 557 times
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  • Site-wide: 53,053
  • In genetics: 2,365
• Year to date:
  • Site-wide: 100,579
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  • Site-wide: 24,524

Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics

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  • Site-wide: 56,955
  • In genomics: 4,247
• Year to date:
  • Site-wide: 116,486
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  • Site-wide: 79,964

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

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  • Site-wide: 59,947
  • In genetics: 2,675
• Year to date:
  • Site-wide: 142,739
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  • Site-wide: 140,936

Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways

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  • Site-wide: 66,957
  • In epidemiology: 2,919
• Year to date:
  • Site-wide: 116,100
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  • Site-wide: 62,326

Response to Therapeutic Sleep Deprivation: A Naturalistic Study of Clinical and Genetic Factors and Post-Treatment Depressive Symptom Trajectory

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  • Site-wide: 85,449
  • In epidemiology: 3,583
• Year to date:
  • Site-wide: 143,758
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  • Site-wide: 142,509

Exemplar Scoring Identifies Genetically Separable Phenotypes of Lithium Responsive Bipolar Disorder

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  • Site-wide: 97,864
  • In psychiatry and clinical psychology: 391
• Year to date:
  • Site-wide: 75,710
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  • Site-wide: 50,686

Characterization of Age and Polarity at Onset in Bipolar Disorder

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  • Site-wide: 114,544
  • In psychiatry and clinical psychology: 494
• Year to date:
  • Site-wide: 24,550
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  • Site-wide: 43,407

Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning

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  • Site-wide: 114,825
  • In psychiatry and clinical psychology: 495
• Year to date:
  • Site-wide: 24,647
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  • Site-wide: 48,461

"The Heidelberg Five" Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after Assessment

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  • Site-wide: 116,617
  • In genomics: 6,587
• Year to date:
  • Site-wide: 103,084
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  • Site-wide: 144,597

Genetic Contributions to Alcohol Use Disorder Treatment Outcomes: A Genome-wide Pharmacogenomics Study

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  • Site-wide: 121,498
  • In genetic and genomic medicine: 637
• Year to date:
  • Site-wide: 28,861
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  • Site-wide: 27,362

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

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  • Site-wide: 125,107
  • In psychiatry and clinical psychology: 589
• Year to date:
  • Site-wide: 31,820
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  • Site-wide: 63,031

Connection Failure: Differences in White Matter Microstructure are associated with 5-HTTLPR but not with Risk-Seeking for Losses

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  • Site-wide: 147,477
  • In neuroscience: 22,189
• Year to date:
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  • Site-wide: 74,022