Author: Marcella Rietschel

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,695 times
• Download rankings, all-time:
  • Site-wide: 1,321
  • In genetics: 26
• Year to date:
  • Site-wide: 38,225
• Since beginning of last month:
  • Site-wide: 28,753

The genetic architecture of the human cerebral cortex

• Downloaded 8,426 times
• Download rankings, all-time:
  • Site-wide: 1,582
  • In genetics: 35
• Year to date:
  • Site-wide: 24,828
• Since beginning of last month:
  • Site-wide: 31,052

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,602 times
• Download rankings, all-time:
  • Site-wide: 1,792
  • In genetics: 41
• Year to date:
  • Site-wide: 64,507
• Since beginning of last month:
  • Site-wide: 55,270

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

• Downloaded 4,453 times
• Download rankings, all-time:
  • Site-wide: 3,714
  • In systems biology: 46
• Year to date:
  • Site-wide: 86,623
• Since beginning of last month:
  • Site-wide: 66,389

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

• Downloaded 3,452 times
• Download rankings, all-time:
  • Site-wide: 5,325
  • In psychiatry and clinical psychology: 21
• Year to date:
  • Site-wide: 12,956
• Since beginning of last month:
  • Site-wide: 7,606

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 2,705 times
• Download rankings, all-time:
  • Site-wide: 7,581
  • In genetics: 351
• Year to date:
  • Site-wide: 2,905
• Since beginning of last month:
  • Site-wide: 11,885

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

• Downloaded 2,634 times
• Download rankings, all-time:
  • Site-wide: 7,902
  • In genetics: 339
• Year to date:
  • Site-wide: 9,092
• Since beginning of last month:
  • Site-wide: 28,831

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

• Downloaded 2,063 times
• Download rankings, all-time:
  • Site-wide: 11,361
  • In neurology: 29
• Year to date:
  • Site-wide: 16,769
• Since beginning of last month:
  • Site-wide: 11,690

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

• Downloaded 2,014 times
• Download rankings, all-time:
  • Site-wide: 11,769
  • In genetics: 434
• Year to date:
  • Site-wide: 111,942
• Since beginning of last month:
  • Site-wide: 91,258

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,928 times
• Download rankings, all-time:
  • Site-wide: 12,534
  • In genetics: 470
• Year to date:
  • Site-wide: 154,816
• Since beginning of last month:
  • Site-wide: 125,297

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

• Downloaded 1,861 times
• Download rankings, all-time:
  • Site-wide: 13,220
  • In genetics: 498
• Year to date:
  • Site-wide: 127,008
• Since beginning of last month:
  • Site-wide: 124,938

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

• Downloaded 1,763 times
• Download rankings, all-time:
  • Site-wide: 14,347
  • In genetics: 564
• Year to date:
  • Site-wide: 103,109
• Since beginning of last month:
  • Site-wide: 114,071

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,560 times
• Download rankings, all-time:
  • Site-wide: 17,252
  • In genomics: 1,529
• Year to date:
  • Site-wide: 109,099
• Since beginning of last month:
  • Site-wide: 112,144

Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

• Downloaded 1,426 times
• Download rankings, all-time:
  • Site-wide: 19,785
  • In genetics: 940
• Year to date:
  • Site-wide: 16,802
• Since beginning of last month:
  • Site-wide: 14,221

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

• Downloaded 1,350 times
• Download rankings, all-time:
  • Site-wide: 21,562
  • In genetics: 849
• Year to date:
  • Site-wide: 180,963
• Since beginning of last month:
  • Site-wide: 190,222

Genomic architecture of human neuroanatomical diversity

• Downloaded 1,203 times
• Download rankings, all-time:
  • Site-wide: 25,814
  • In neuroscience: 2,850
• Year to date:
  • Site-wide: 189,712
• Since beginning of last month:
  • Site-wide: 186,601

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 1,020 times
• Download rankings, all-time:
  • Site-wide: 33,118
  • In genetics: 1,534
• Year to date:
  • Site-wide: 30,604
• Since beginning of last month:
  • Site-wide: 33,530

Pharmacogenetics of antidepressant response: a polygenic approach

• Downloaded 958 times
• Download rankings, all-time:
  • Site-wide: 36,362
  • In genetics: 1,431
• Year to date:
  • Site-wide: 165,194
• Since beginning of last month:
  • Site-wide: 100,997

Planar cell polarity pathway and development of the human visual cortex

• Downloaded 952 times
• Download rankings, all-time:
  • Site-wide: 36,703
  • In neuroscience: 4,615
• Year to date:
  • Site-wide: 78,120
• Since beginning of last month:
  • Site-wide: 52,188

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 945 times
• Download rankings, all-time:
  • Site-wide: 37,101
  • In genetics: 1,450
• Year to date:
  • Site-wide: 164,977
• Since beginning of last month:
  • Site-wide: 136,808

Polygenic scores for major depressive disorder and depressive symptoms predict response to lithium in patients with bipolar disorder

• Downloaded 929 times
• Download rankings, all-time:
  • Site-wide: 38,079
  • In genomics: 2,926
• Year to date:
  • Site-wide: 118,784
• Since beginning of last month:
  • Site-wide: 102,226

Generative network models identify biological mechanisms of altered structural brain connectivity in schizophrenia

• Downloaded 852 times
• Download rankings, all-time:
  • Site-wide: 43,230
  • In neuroscience: 5,347
• Year to date:
  • Site-wide: 131,116
• Since beginning of last month:
  • Site-wide: 155,722

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 827 times
• Download rankings, all-time:
  • Site-wide: 45,169
  • In genetics: 1,775
• Year to date:
  • Site-wide: 109,253
• Since beginning of last month:
  • Site-wide: 77,299

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

• Downloaded 781 times
• Download rankings, all-time:
  • Site-wide: 49,151
  • In neuroscience: 6,391
• Year to date:
  • Site-wide: 108,106
• Since beginning of last month:
  • Site-wide: 77,026

Higher genetic risk for schizophrenia is associated with living in urban and populated areas

• Downloaded 722 times
• Download rankings, all-time:
  • Site-wide: 54,952
  • In genetics: 2,118
• Year to date:
  • Site-wide: 155,350
• Since beginning of last month:
  • Site-wide: 182,342

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

• Downloaded 691 times
• Download rankings, all-time:
  • Site-wide: 58,459
  • In genomics: 4,000
• Year to date:
  • Site-wide: 162,078
• Since beginning of last month:
  • Site-wide: 150,682

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 674 times
• Download rankings, all-time:
  • Site-wide: 60,578
  • In genomics: 4,066
• Year to date:
  • Site-wide: 175,514
• Since beginning of last month:
  • Site-wide: 187,348

High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis

• Downloaded 649 times
• Download rankings, all-time:
  • Site-wide: 63,622
  • In genetics: 2,405
• Year to date:
  • Site-wide: 183,990
• Since beginning of last month:
  • Site-wide: 189,594

Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics

• Downloaded 615 times
• Download rankings, all-time:
  • Site-wide: 68,273
  • In genomics: 4,471
• Year to date:
  • Site-wide: 159,749
• Since beginning of last month:
  • Site-wide: 180,442

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 602 times
• Download rankings, all-time:
  • Site-wide: 70,196
  • In genetics: 2,668
• Year to date:
  • Site-wide: 185,637
• Since beginning of last month:
  • Site-wide: 179,979

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

• Downloaded 548 times
• Download rankings, all-time:
  • Site-wide: 78,770
  • In genetics: 3,058
• Year to date:
  • Site-wide: 150,944
• Since beginning of last month:
  • Site-wide: 138,034

Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways

• Downloaded 492 times
• Download rankings, all-time:
  • Site-wide: 89,540
  • In epidemiology: 3,617
• Year to date:
  • Site-wide: 160,924
• Since beginning of last month:
  • Site-wide: 170,448

Characterization of Age and Polarity at Onset in Bipolar Disorder

• Downloaded 455 times
• Download rankings, all-time:
  • Site-wide: 97,633
  • In psychiatry and clinical psychology: 478
• Year to date:
  • Site-wide: 48,317
• Since beginning of last month:
  • Site-wide: 20,882

Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning

• Downloaded 409 times
• Download rankings, all-time:
  • Site-wide: 108,321
  • In psychiatry and clinical psychology: 577
• Year to date:
  • Site-wide: 56,936
• Since beginning of last month:
  • Site-wide: 19,959

Response to Therapeutic Sleep Deprivation: A Naturalistic Study of Clinical and Genetic Factors and Post-Treatment Depressive Symptom Trajectory

• Downloaded 388 times
• Download rankings, all-time:
  • Site-wide: 113,698
  • In epidemiology: 4,535
• Year to date:
  • Site-wide: 174,811
• Since beginning of last month:
  • Site-wide: 164,724

Exemplar Scoring Identifies Genetically Separable Phenotypes of Lithium Responsive Bipolar Disorder

• Downloaded 385 times
• Download rankings, all-time:
  • Site-wide: 114,628
  • In psychiatry and clinical psychology: 524
• Year to date:
  • Site-wide: 113,878
• Since beginning of last month:
  • Site-wide: 116,801

Genetic Contributions to Alcohol Use Disorder Treatment Outcomes: A Genome-wide Pharmacogenomics Study

• Downloaded 380 times
• Download rankings, all-time:
  • Site-wide: 115,910
  • In genetic and genomic medicine: 782
• Year to date:
  • Site-wide: 56,913
• Since beginning of last month:
  • Site-wide: 17,622

Multi-Omics Signatures of Alcohol Use Disorder in the Dorsal and Ventral Striatum

• Downloaded 378 times
• Download rankings, all-time:
  • Site-wide: 116,468
  • In addiction medicine: 89
• Year to date:
  • Site-wide: 29,490
• Since beginning of last month:
  • Site-wide: 38,250

Epigenome-wide Association Study of Alcohol Use Disorder in Five Brain Regions

• Downloaded 360 times
• Download rankings, all-time:
  • Site-wide: 121,356
  • In addiction medicine: 81
• Year to date:
  • Site-wide: 83,542
• Since beginning of last month:
  • Site-wide: 81,035

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

• Downloaded 348 times
• Download rankings, all-time:
  • Site-wide: 124,731
  • In psychiatry and clinical psychology: 683
• Year to date:
  • Site-wide: 56,852
• Since beginning of last month:
  • Site-wide: 21,679

"The Heidelberg Five" Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after Assessment

• Downloaded 279 times
• Download rankings, all-time:
  • Site-wide: 144,817
  • In genomics: 7,314
• Year to date:
  • Site-wide: 163,552
• Since beginning of last month:
  • Site-wide: 133,745

Interplay between the Genetics of Personality Traits, severe Psychiatric Disorders, and COVID-19 Host Genetics in the Susceptibility to SARS-CoV-2 Infection

• Downloaded 237 times
• Download rankings, all-time:
  • Site-wide: 157,149
  • In genetic and genomic medicine: 998
• Year to date:
  • Site-wide: 101,594
• Since beginning of last month:
  • Site-wide: 80,537

Connection Failure: Differences in White Matter Microstructure are associated with 5-HTTLPR but not with Risk-Seeking for Losses

• Downloaded 171 times
• Download rankings, all-time:
  • Site-wide: 174,010
  • In neuroscience: 24,745
• Year to date:
  • Site-wide: 101,145
• Since beginning of last month:
  • Site-wide: 64,446

Psychological, endocrine and polygenic predictors of emotional well-being during the COVID-19 pandemic

• Downloaded 158 times
• Download rankings, all-time:
  • Site-wide: 176,763
  • In psychiatry and clinical psychology: 1,203
• Year to date:
  • Site-wide: 27,725
• Since beginning of last month:
  • Site-wide: 48,830