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Author: Wolfgang Huber

Rankings

  • All-time downloads: 64,335 (rank: 504 out of 360,013)
  • Categories:
    • bioengineering: 1,566 (rank: 964 (tie) out of 10,011)
    • bioinformatics: 42,196 (rank: 59 out of 31,165)
    • cancer biology: 2,938 (rank: 890 (tie) out of 24,449)
    • cell biology: 1,328 (rank: 2,831 out of 26,385)
    • genomics: 11,355 (rank: 1,126 out of 39,006)
    • molecular biology: 2,736 (rank: 715 out of 18,289)
    • systems biology: 2,216 (rank: 1,151 out of 10,774)

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Preprints

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

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HTSeq - A Python framework to work with high-throughput sequencing data

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Multi-Omics factor analysis - a framework for unsupervised integration of multi-omic data sets

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Two independent modes of chromosome organization are revealed by cohesin removal

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Orchestrating Single-Cell Analysis with Bioconductor

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Data-driven hypothesis weighting increases detection power in multiple testing

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A user’s guide to the online resources for data exploration, visualization, and discovery for the Pan-Cancer Analysis of Whole Genomes project (PCAWG)

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Condensin II inactivation in interphase does not affect chromatin folding or gene expression

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SomaticSignatures: Inferring Mutational Signatures from Single Nucleotide Variants

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Mutated SF3B1 is associated with transcript isoform changes of the genes UQCC and RPL31 both in CLLs and uveal melanomas

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Transcript Isoform Differences Across Human Tissues Are Predominantly Driven By Alternative Start And Termination Sites Of Transcription

genomics more details view paper
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    • In genomics: 770 out of 5,407
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Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

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    • In systems biology: 122 out of 2,211
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Biological Plasticity Rescues Target Activity in CRISPR Knockouts

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    • In bioengineering: 93 out of 1,810
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The small non-coding vault RNA1-1 acts as a riboregulator of autophagy

molecular biology more details view paper
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    • In molecular biology: 182 out of 2,801
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    • Site-wide: 25,977 out of 83,521

Non-parametric analysis of thermal proteome profiles reveals novel drug-binding proteins

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    • In bioinformatics: 1,094 out of 8,009
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FourCSeq: Analysis of 4C sequencing data

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Neural lineage induction reveals multi-scale dynamics of 3D chromatin organization

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    • In molecular biology: 244 out of 2,801
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Modelling asymmetric count ratios in CRISPR screens to decrease experiment size and improve phenotype detection

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    • In bioinformatics: 1,728 out of 8,009
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    • Site-wide: 19,691 out of 83,521

A combinatorial extracellular code tunes the intracellular signaling network activity to distinct cellular responses

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    • In cell biology: 833 out of 4,242
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Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo

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    • In cell biology: 878 out of 4,242
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Developmental gene expression differences between humans and mammalian models

genomics more details view paper
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    • In genomics: 2,466 out of 5,407
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    • Site-wide: 13,650 out of 83,521

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

systems biology more details view paper
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    • In systems biology: 644 out of 2,211
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Dissecting intratumor heterogeneity of nodal B cell lymphomas on the transcriptional, genetic, and drug response level

cancer biology more details view paper
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    • In cancer biology: 715 out of 2,914
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MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma

cancer biology more details view paper
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    • In cancer biology: 838 out of 2,914
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Computational analysis of ligand dose range thermal proteome profiles

bioinformatics more details view paper
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