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Author: Han Chen

Rankings

  • All-time downloads: 14,546 (rank: 10,002 out of 513,978)
  • Categories:
    • bioinformatics: 1,752 (rank: 7,317 (tie) out of 37,097)
    • cancer biology: 87 (rank: 30,292 (tie) out of 31,671)
    • cell biology: 86 (rank: 33,127 (tie) out of 34,140)
    • epidemiology: 265 (rank: 17,358 (tie) out of 23,860)
    • evolutionary biology: 689 (rank: 8,672 (tie) out of 22,356)
    • genetics: 3,185 (rank: 5,390 (tie) out of 38,823)
    • genomics: 1,803 (rank: 11,470 out of 45,850)
    • microbiology: 1,609 (rank: 6,814 (tie) out of 52,513)
    • molecular biology: 968 (rank: 4,739 (tie) out of 24,319)
    • neuroscience: 3,615 (rank: 4,689 (tie) out of 73,739)
    • systems biology: 487 (rank: 7,282 (tie) out of 12,940)

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Preprints

Spatiotemporal limits of optogenetic manipulations in cortical circuits

neuroscience more details view paper
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AnnoTree: visualization and exploration of a functionally annotated microbial tree of life

bioinformatics more details view paper
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    • In bioinformatics: 1,821 out of 9,634
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Single-cell profiling of Ebola virus infection in vivo reveals viral and host transcriptional dynamics

microbiology more details view paper
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Phytophthora methylomes modulated by expanded 6mA methyltransferases are associated with adaptive genome regions

molecular biology more details view paper
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Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

genetics more details view paper
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The non-essentiality of essential genes suggests a loss-of-function therapeutic strategy for loss-of-function human diseases

genetics more details view paper
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Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages

microbiology more details view paper
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    • In microbiology: 2,222 out of 9,410
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    • Site-wide: 90,955 out of 119,207

Multiethnic catalog of structural variants and their translational impact for disease phenotypes across 19,652 genomes

genomics more details view paper
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    • In genomics: 3,251 out of 6,457
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    • Site-wide: 98,373 out of 119,207

Natural selection defines the cellular complexity

evolutionary biology more details view paper
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    • In evolutionary biology: 2,360 out of 6,216
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    • Site-wide: 108,605 out of 119,207

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
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    • In genomics: 3,703 out of 6,457
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    • Site-wide: 62,288 out of 119,207

Principles of studying a cell - a non-boastful paper for all molecular biologists

systems biology more details view paper
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    • In systems biology: 1,105 out of 2,652
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    • Site-wide: 105,446 out of 119,207

The regulator-executor-phenotype architecture shaped by natural selection

genetics more details view paper
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    • In genetics: 2,597 out of 5,153
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    • Site-wide: 96,370 out of 119,207

Whole-Genome Association Analyses of Sleep-disordered Breathing Phenotypes in the NHLBI TOPMed Program

genetics more details view paper
  • Downloaded 394 times
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    • Site-wide: 56,524 out of 119,207
    • In genetics: 2,780 out of 5,153
  • Year to date:
    • Site-wide: 57,723 out of 119,207
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    • Site-wide: 73,759 out of 119,207

Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole Genome Sequencing Studies

genetics more details view paper
  • Downloaded 357 times
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    • Site-wide: 62,053 out of 119,207
    • In genetics: 3,012 out of 5,153
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    • Site-wide: 84,132 out of 119,207

GEM: Scalable and flexible gene-environment interaction analysis in millions of samples

bioinformatics more details view paper
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    • Site-wide: 62,164 out of 119,207
    • In bioinformatics: 6,195 out of 9,634
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    • Site-wide: 16,753 out of 119,207

A unified method for rare variant analysis of gene-environment interactions

genetics more details view paper
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    • In genetics: 3,399 out of 5,153
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Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American specific associations

genomics more details view paper
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    • In genomics: 4,926 out of 6,457
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    • Site-wide: 60,164 out of 119,207

Estimation of Mediation Effect for High-dimensional Omics Mediators with Application to the Framingham Heart Study

genomics more details view paper
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    • In genomics: 5,156 out of 6,457
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    • Site-wide: 74,959 out of 119,207

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

epidemiology more details view paper
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    • In epidemiology: 3,148 out of 4,690
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    • Site-wide: 94,970 out of 119,207

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

bioinformatics more details view paper
  • Downloaded 261 times
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    • Site-wide: 79,174 out of 119,207
    • In bioinformatics: 7,284 out of 9,634
  • Year to date:
    • Site-wide: 31,841 out of 119,207
  • Since beginning of last month:
    • Site-wide: 25,675 out of 119,207

Efficient gene-environment interaction tests for large biobank-scale sequencing studies

genetics more details view paper
  • Downloaded 239 times
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    • Site-wide: 83,634 out of 119,207
    • In genetics: 3,965 out of 5,153
  • Year to date:
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    • Site-wide: 51,698 out of 119,207

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 180 times
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    • Site-wide: 95,453 out of 119,207
    • In genomics: 5,785 out of 6,457
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    • Site-wide: 41,197 out of 119,207

Multi-locus characterization and phylogenetic inference of Leishmania spp. in snakes from Northwest China

evolutionary biology more details view paper
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    • In evolutionary biology: 5,375 out of 6,216
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Efficiency of a Randomized Confirmatory Basket Trial Design Constrained to Control the False Positive Rate by Indication

cancer biology more details view paper
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    • In cancer biology: 3,500 out of 3,772
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    • Site-wide: 114,943 out of 119,207

Extracellular vesicles from retinal pigment epithelial cells expressing R345W-Fibulin-3 induce epithelial-mesenchymal transition in recipient cells

cell biology more details view paper
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    • In cell biology: 5,174 out of 5,459
  • Year to date:
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    • Site-wide: 44,691 out of 119,207

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